More bad news from their press release unrelated to their vaccine. their trial found 1/3 of South African subjects already had antibodies for the original strain but still got infected and developed symptoms from the new variant. Additional data on natural immunity not being great against E484K mutation (South African strain):

“ approximately 1/3 of the patients enrolled (but not included in the primary analyses described above) were seropositive, demonstrating prior COVID-19 infection at baseline. Based on temporal epidemiology data in the region, the pre-trial infections are thought to have been caused by the original COVID-19 strain (i.e., non-variant), while the subsequent infections during the study were largely variant virus. These data suggest that prior infection with COVID-19 may not completely protect against subsequent infection by the South Africa escape variant”