Moderna Covid vaccine candidate almost 95% effective, trials show

Demandedace · 2020-11-16T14:36:58+00:00

For a bit of perspective, the Measles vaccine is 93% effective. This is huge.

StevenSanders90210 · 2020-11-16T12:52:07+00:00

While Pfizer’s vaccine requires ultracold freezing between -70C and -80C from production facility to patient, Moderna said it had improved the shelf life and stability of its own vaccine, meaning that it can be stored at standard refrigeration temperatures of 2C to 8C for 30 days. It can be stored for six months at -20C for shipping and long-term storage, the company said.

This is also very promising news. Getting it to everyone will be much easier.

suchascenicworld · 2020-11-16T13:42:17+00:00

According to a CNN article:

"In Moderna's trial, 15,000 study participants were given a placebo, which is a shot of saline that has no effect. Over several months, 90 of them developed Covid-19, with 11 developing severe forms of the disease. Another 15,000 participants were given the vaccine, and only five of them developed Covid-19. None of the five became severely ill."

I do not know much about about vaccines, but that seems absolutely amazing.

Source: https://www.cnn.com/2020/11/16/health/moderna-vaccine-results-coronavirus/index.html

therealsix · 2020-11-16T12:56:58+00:00

Very promising. I really like the fact that the storage and life of the vaccine is more manageable. Please please please work.

DuxofOregon · 2020-11-16T14:26:12+00:00

God, I hope this works. Need to get back to licking door handles ASAP.

Pahasapa66 · 2020-11-16T12:48:14+00:00

Excellent news. Moderna’s vaccine is being co-developed with Fauci’s NIAID institute, and being tested in 30,000 people.

gmil3548 · 2020-11-16T14:35:46+00:00

My dad is in the Astra-Zeneca trial that’s also supposedly about this effective. I think there may be multiple vaccines finished in the next couple months.

2tidderevoli · 2020-11-16T12:10:29+00:00

Two very effective vaccines. Maybe more to come. Very promising. 2021 might be the antidote to 2020

wicktus · 2020-11-16T13:45:19+00:00

This is a really great news.

The 5% also did not develop serious complications of COVID. What will be important once vaccines are out is the number of patients going into ICU/hospitals, if we are ALL either asymptomatic or have mild symptoms, there is no need to worry anymore, it's really the number of hospital entries/death/long-term complications that will be the benchmark, not the number of positive cases imo.

S1NN1ST3R · 2020-11-16T14:05:40+00:00

Wow I haul pharmaceuticals, crazy to think I'll probably be delivering vaccines all over North America.

DarkStarStorm · 2020-11-16T13:47:07+00:00

I never thought I could get this excited about a shot.

Gig4t3ch · 2020-11-16T12:31:23+00:00

According to the guy in charge of the Operation Warp Speed Program, Moncef Slaoui, all of the vaccine candidates for Operation Warp Speed have around 80% efficacy:

My expectation is really something between 80% and 90% efficacy

There hasn't really been much negative news about vaccines coming from Western countries, so things look pretty good for a summer where most people in the Western world will be vaccinated.

Butagami · 2020-11-16T14:32:45+00:00

2021 has the easiest job ever to be remembered as an incredible year. All it has to do is not be 2020 and it’ll be looked upon with great favor lol

Joebebs · 2020-11-16T14:28:20+00:00

I love this competition. Hearing a second company having similar -if not better- results are promising

Baptism-Of-Fire · 2020-11-16T15:24:07+00:00

Give it to me now, I’ll inject it straight into my asshole. I don’t care. I’m sick of this fearful year.

Bobaximus · 2020-11-16T14:00:56+00:00

The fact that it doesn’t need the same level of refrigeration is very important.

citygirldc · 2020-11-16T14:15:56+00:00

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FaceInTheSpace · 2020-11-16T14:19:36+00:00

Russian announcement tomorrow: our vaccine is 97% effective

2020-11-16T15:48:34+00:00

I’m sure this is disappointing all the fans of end times movies

imapilotaz · 2020-11-16T13:24:34+00:00

Wonder if I was part of the placebo group or not. 95% sounds pretty good though.

Razzlesdazzle · 2020-11-16T14:41:09+00:00

I'm excited to help contribute to this study! My doctor said new data might be available around the 22nd, since most of the participants have gone in for their third blood draw. Next one will be in 5/6? months.

Pfizer data came out earlier because there is 3 weeks in between those shots versus 4 for the Moderna. Each time we went in we also had our blood drawn so they could check out antibody levels and all that other science-y type stuff.

boogi3woogie · 2020-11-16T13:50:11+00:00

Stonks going up today

TerminusFox · 2020-11-16T13:21:36+00:00

Got a question for those in virology, epidemiology, etc.

With just how “fast” these vaccines are being made, is this evidence that the time we spent on other vaccines wasn’t warranted and they technically could’ve been made faster if a company wanted to or is this simply a unique situation?

Is there any promising biotechnology coming up that will help us produce vaccines for viruses much quicker in the coming decades?

jamesda123 · 2020-11-16T14:24:30+00:00

Hopefully the immunity is long-lived. Moderna's mRNA platform seems to cause a lot of limiting toxicities with repeated dosing.

Moderna’s promise — and the more than $2 billion it raised before going public in 2018 — hinged on creating a fleet of mRNA medicines that could be safely dosed over and over. But behind the scenes the company’s scientists were running into a familiar problem. In animal studies, the ideal dose of their leading mRNA therapy was triggering dangerous immune reactions — the kind for which Karikó had improvised a major workaround under some conditions — but a lower dose had proved too weak to show any benefits.

Moderna had to pivot. If repeated doses of mRNA were too toxic to test in human beings, the company would have to rely on something that takes only one or two injections to show an effect. Gradually, biotech’s self-proclaimed disruptor became a vaccines company, putting its experimental drugs on the back burner and talking up the potential of a field long considered a loss-leader by the drug industry.

chezmanny · 2020-11-16T14:26:06+00:00

I am in the Moderna trial, and got the injections about 4 months ago.

I am 90% sure I received the vaccine, not the placebo. Side effects were very mild, and I drive Uber. So if I didn't get the real thing, I would have probably caught the virus by now.

k_ironheart · 2020-11-16T15:08:54+00:00

The fact that we have not one, but two potential vaccines that are potentially hitting the 90+% efficiency mark is some of the best medical news all year.

That said, though, I'm afraid of what the next few months are going to bring. People are going to see that we have a vaccine coming, and not understand that it's probably a half a year or more away from wide distribution. Meanwhile, we have record deaths and new cases every single day.

The best thing we could do right now is another shutdown with meaningful social safety nets to try to slow the spread of the virus so our medical staff don't get overwhelmed, but our current leadership in the US doesn't give a fuck about anything right now, except for working one last scam on their voters.

AllenMcnabb · 2020-11-16T14:06:30+00:00

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