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- U & I Nonprofit Corporation
- U S Green Building Council Inc
- U S Green Building Council- Minnesota Chapter Inc
- U S Space Walk of Fame Foundation
- U Turn For Christ Greeneville
- U.S. Capitol Historical Society
- U.S. Veterans Rowing & Kayaking Foundation
- UC Berkeley SAGE Scholars Program
- UCAN
- UCOM UrbanServ Inc
- UCP Central PA
- Udavum Karangal Of Usa
- Udayan Care
- Udyama
- Ugandan Lambs Association USA
- Uja Federation of Greenwich
- Ukraine Orphan Outreach
- Ulman Cancer Fund For Young Adults
- Ulster County SPCA
- Umbrella of the Capital District, Inc.
- Umma-Urban Muslim Minority Alliance
- Umoja Student Development Corporation
- Umps Care Charities Inc
- Unbound
- Uncle Asia
- Under My Wing Avian Refuge AKA Under My Wing AKA UMWAR
- Under One Roof, Inc.
- Undies for Everyone
- Unidos Por La Musica
- Unified Progress International (UPI) Education Inc.
- Uniformed Services Justice & Advocacy Group (USJAG)
- Uniformed Services Peer Council
- Unifour One
- Union County Historical Society
- Union Gospel Mission of Tarrant County
- Union Gospel Mission Sacramento
- Union of Concerned Scientists, Inc.
- Union Project
- Union Rescue Mission
- Union Station Homeless Services
- Unitarian Fellowship for World Peace
- Unite For Her
- Unite Oregon
- Unite to Light
- United Animal Coalition Inc
- United Arts Council of Greensboro Inc
- United Brachial Plexus Network
- United By Friendship Inc
- United Cancer Support Foundation
- United Cerebral Palsy (UCP) of Central Florida, Inc.
- United Cerebral Palsy of Greater Dane County, Inc.
- United Cerebral Palsy of South Carolina Inc
- United Charitable
- United Community Ministries, Inc.
- United Food Bank
- United for a Fair Economy, Inc.
- United for the People
- United Fund Of Cumberland County Inc
- United Global Outreach Inc
- United Horsemens Front
- United in Light, Inc.
- United International Buddha Dhamma Inc
- United Methodist Childrens Home
- United Methodist Childrens Home Of North Georgia Conference Inc
- United Methodist Church & Its Affiliated Organizations
- United Methodist Family Services of Virginia (UMFS)
- United Methodist Neighborhood Centers, Inc.
- UNITED MIDCOAST CHARITIES INC
- United Military Care Inc.
- United Ministries, Inc.
- United Mitochondrial Disease Foundation Inc
- United Muslim Relief Umr
- United Negro College Fund Inc
- United Neighborhood Centers of Northeastern Pennsylvania
- United Planet
- United Playaz Inc
- United Service Organizations
- United Service Organizations Inc
- United Sikhs
- United Soldiers and Sailors of America - USASOA
- United Spinal Association
- United States Catholic Conference
- United States Catholic Conference
- United States Fund For Unicef
- United States Institute for Theatre Technology Inc
- United States Marine Corps Motor Transport Association Inc
- United States Mission Corporation
- United States Olympic Committee
- United States Veterans Initiative
- United States Veterans' Artists Alliance (USVAA)
- UNITED STATES WAR VETERANS PTSD FOUNDATION
- United States Wolf Refuge and Adoption Center
- United States Zoological Association
- United Steelworkers
- United Support Against Multiple Sclerosis
- United Survivors Of Epidermolysisbullosa Corporation
- United To End Genocide
- United Veterans Beacon House Inc
- United War Veterans Council Inc
- United Way Association of South Carolina Inc