Accepted for Publication: October 19, 2021.
Published Online: November 5, 2021. doi:10.1001/jama.2021.19885
Corresponding Author: Salomon M. Stemmer, MD, Davidoff Cancer Center, Rabin Medical Center, Belinson Hospital, Sackler Faculty of Medicine, Tel Aviv University, 39 Jabotinsky St, Petah Tikva 49100, Israel (salomon.stemmer@gmail.com).
Author Contributions: Dr S. M. Stemmer had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Eliakim-Raz and Leibovici-Weisman contributed equally to this work.
Concept and design: Eliakim-Raz, Leibovici-Weisman, S. M. Stemmer.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: All authors.
Critical revision of the manuscript for important intellectual content: Eliakim-Raz, Leibovici-Weisman, A. Stemmer, S. M. Stemmer.
Statistical analysis: A. Stemmer, S. M. Stemmer.
Obtained funding: S. M. Stemmer.
Administrative, technical, or material support: Eliakim-Raz, Leibovici-Weisman, Ness, Awwad, Ghantous, S. M. Stemmer.
Supervision: Eliakim-Raz, Leibovici-Weisman, S. M. Stemmer.
Conflict of Interest Disclosures: Dr S. M. Stemmer reported receiving research grants (to his institution) from CAN-FITE, AstraZeneca, BioLineRX, BMS, Clovis Oncology, CTG Pharma, Exelixis, GEICAM, Halozyme, Incyte, Lilly, Moderna, Teva Pharmaceuticals, and Roche, and owns stocks and options in CTG Pharma, DocBoxMD, TyrNovo, VYPE, Cytora, and CAN-FITE. No other disclosures were reported.
Data Sharing Statement: The data sets generated during this study are available from the corresponding author on request.
Additional Contributions: We thank Avital Bareket-Samish, PhD, BioInsight Ltd, for medical editing support. She received financial compensation for her contribution.
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