A power supply unit (PSU) converts mains AC to low-voltage regulated DC power for the internal components of the computer. Modern personal computers universally use a switched-mode power supply. Some power supplies have a manual selector for input voltage, while others automatically adapt to the supply voltage.

Most modern desktop personal computer power supplies conform to the ATX form factor. ATX power supplies are turned on and off by a signal from the motherboard. They also provide a signal to the motherboard to indicate when the DC power lines are correct so that the computer is able to boot up. While an ATX power supply is connected to the mains supply it provides a 5 V stand-by (5VSB) line so that the standby functions on the computer and certain peripherals are powered. The most recent ATX PSU standard is version 2.31 of mid-2008.

The desktop computer power supply changes alternating current from a wall socket to low-voltage direct current to operate the processor and peripheral devices. Several direct-current voltages are required, and they must be regulated with some accuracy to provide stable operation of the computer. A power supply rail or voltage rail refers to a single voltage provided by a power supply unit (PSU). Although the term is generally used in electronic engineering, many people, especially computer enthusiasts, encounter it in the context of personal computer power supplies.

A power supply is a device that supplies electric power to one or more electric loads. The term is most commonly applied to devices that convert one form of electrical energy to another, though it may also refer to devices that convert another form of energy (mechanical, chemical, solar) to electrical energy. A regulated power supply is one that controls the output voltage or current to a specific value; the controlled value is held nearly constant despite variations in either load current or the voltage supplied by the power supply's energy source.

Every power supply must obtain the energy it supplies to its load, as well as any energy it consumes while performing that task, from an energy source. Depending on its design, a power supply may obtain energy from:

A power supply may be implemented as a discrete, stand-alone device or as an integral device that is hardwired to its load. Examples of the latter case include the low voltage DC power supplies that are part of desktop computers and consumer electronics devices.