Ethylone

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Ethylone
Systematic (IUPAC) name
(RS)-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)propan-1-one
Clinical data
Pregnancy cat. N (US)
Legal status Unscheduled
Routes Oral, nasal, IV
Identifiers
ATC code  ?
ChemSpider 21106271
Chemical data
Formula C12H15NO3 
Mol. mass 221.2524 g/mol
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Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, bk-MDEA), is an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone. Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone.

Contents

[edit] Pharmokinetics

Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[1]

  1. N-demethylation to the primary amine.
  2. Reduction of the keto moiety to the respective alcohol.
  3. Oxidation of the tolyl moiety to the corresponding alcohols and carboxylic acid.

[edit] See also

[edit] References

  1. ^ Meyer, Markus R; Jens Wilhelm, Frank T. Peters, Hans H. Maurer (2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". ANALYTICAL AND BIOANALYTICAL CHEMISTRY 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362. Retrieved 19 September 2012. 

[edit] External links