Tazolol

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Tazolol


Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	39832-48-9
ATC code	?
PubChem	CID 71721
ChemSpider	64770
UNII	B64Q38TX4G^Y
Chemical data
Formula	C₉H₁₆N₂O₂S

Tazolol is a beta blocker with some utility in the treatment of heart disease.^[1]

Chemical synthesis[edit]

Tazolol synthesis.png

References[edit]

^ Strosberg AM. (1976). "The cardiovascular pharmacology and hemodynamic activity of tazolol, a selective myocardial beta-stimulant". Arch Int Pharmacodyn Ther. 222 (2): 200–15.

Sympatholytic (and closely related) antihypertensives (C02)

Sympatholytics
(antagonize α-adrenergic
vasoconstriction)

Central

α₂ agonist	Clonidine Guanfacine Methyldopa #

Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guanethidine Guanoclor Guanoxan Guanazodine Guanoxabenz Guanoxan

Imidazoline receptor agonist	Moxonidine Rilmenidine

Ganglion-blocking/nicotinic antagonist	Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

MAOI	Pargyline

Adrenergic uptake inhibitor	Bietaserpine Deserpidine Methoserpidine Rescinnamine Reserpine

Tyrosine hydroxylase inhibitor	Metirosine

Direct

α₁ blockers	Prazosin Indoramin Trimazosin Doxazosin Urapidil

Non-selective α blocker	Phentolamine

Other antagonists

Serotonin antagonist	Ketanserin Lidanserin

Endothelin antagonist (for PH)	dual (Bosentan) selective (Ambrisentan, Sitaxentan)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug (C2s+n/3/4/5/7/8/9)

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