The GiveWell Blog

Research Strategy: Vaccines

| by Natalie Crispin

GiveWell started supporting vaccines in 2015 and has made over $160 million in grants to date. With strong results from past work in this space, we’re now exploring how to reach more people with vaccines in low- and middle-income countries. This post discusses our current thinking on vaccines grantmaking and our key hypotheses about where to focus our efforts going forward.

Where are we now?

Before this year, our grants for vaccine programs focused on (a) increasing uptake of the vaccines given to children in the first two years of life, and (b) speeding up the rollout of malaria vaccines.

Relative to other global health approaches, vaccines garner a lot of attention. Governments in high-income countries contribute to Gavi, the Vaccine Alliance, which heavily subsidizes the purchasing of vaccines in the world’s poorest countries and provides cash assistance to help these countries deliver them. The Gates Foundation is also a major contributor to vaccine programs. These efforts have been fairly successful—in 2022, 81% of children in the 57 low-income countries supported by Gavi had received the DTP3 vaccine, which protects against diphtheria, tetanus, and pertussis. DTP3 coverage is often used as a benchmark for progress on vaccination.

This provides both a challenge and an opportunity for finding cost-effective giving opportunities. On the one hand, thankfully, the people who are easiest to reach with vaccines are already being reached, which means more expensive or innovative methods are needed to expand coverage. On the other hand, we can build on the extensive knowledge and infrastructure that already exists.

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September 2024 Open Thread

| by GiveWell Staff

Our goal with hosting quarterly open threads is to give blog readers an opportunity to publicly raise comments or questions about GiveWell or related topics (in the comments section below). As always, you’re also welcome to email us at info@givewell.org or to request a call with GiveWell staff if you have feedback or questions you’d prefer to discuss privately. We’ll try to respond promptly to questions or comments.

You can view previous open threads here.

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August 2024 Updates

| by Chandler Brotak

Every month we send an email newsletter to our supporters sharing recent updates from our work. We publish selected portions of the newsletter on our blog to make this news more accessible to people who visit our website. For key updates from the latest installment, please see below!

If you’d like to receive the complete newsletter in your inbox each month, you can subscribe here.

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Raffles, Deworming, and Statistics

| by Jeremy Rehwaldt

Sometimes statistics can help when it’s hard to decide what to do.

You’re at a local art fair, and they’re raffling off a car worth $10,000. Five hundred tickets are being sold, each for $10. Does it make financial sense to buy a ticket? (For the moment, let’s set aside other questions about raffles and just focus on the benefit for you, the potential ticket-buyer.)

You can use a statistical concept called “expected value” to help you decide. Expected value is calculated by multiplying the probability of each potential outcome by its value, then adding these results together to get the average result of an action.

Let’s figure this out—a car is on the line. First, we multiply the probability of each potential outcome by its value.

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Bringing the Economic Benefits of Reading Glasses into Focus

| by Jeremy Rehwaldt

It started in my early forties, and it’s only gotten worse since then. At first, it was a mild annoyance, but now it affects my quality of life and makes it harder to get things done. I’m definitely not alone—almost every middle-aged person I know has the same problem—and maybe you do too: a condition called presbyopia, a type of age-related vision loss that makes it difficult to see things clearly at close distances.

Luckily, the condition is easily and inexpensively treated with reading glasses, widely available at nearly every corner drug store in the United States. Reading glasses work well, and they’re cheap enough that I have them stashed around my house so a pair is always in reach. But an estimated 510 to 826 million people around the world have presbyopia but do not have corrective glasses.

What we know and what we don’t know

We think that providing reading glasses to people who need them is a promising way to improve their employment opportunities and increase their economic well-being. It makes intuitive sense that being able to see better would improve people’s ability to work, particularly for vision-intensive jobs such as crop cultivation and inspection, manufacturing, or retail work.

Since we’re not as confident as we’d like to be in the effect of distributing reading glasses, we’re co-funding a study to find out more before we allocate significant funding to direct delivery of glasses. We’re recommending a $4.8 million grant for the study.

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What If We Have Extra?

| by Jeremy Rehwaldt

What do you do if you’re in the very fortunate position of having more money than you need to meet your own immediate needs? You might find new things to buy. You might stockpile it for a rainy day. You might donate it to cost-effective global health programs. Or you might do some combination of the three.

GiveWell thinks about that same question.

First, a bit of context: All donations made to GiveWell’s Top Charities Fund, All Grants Fund, and recommended organizations go to the programs we recommend. (We do not take a percentage of donations made to recommended organizations through GiveWell’s website, nor do we receive any fees from organizations for being featured on our site.)

Our own organizational needs are met by donors who choose to direct funding to GiveWell’s operations (by giving to our Unrestricted Fund). In other words, we are supported only by donors who explicitly choose to support GiveWell itself through unrestricted donations.

But what happens when we receive more unrestricted donations than we need? We could choose to spend the funds on something new for the organization. We could squirrel those funds away, building an endowment to cover future needs. Or, like you, we could donate to cost-effective global health programs.

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