- The San Francisco 49ers’ defense is the NFL’s best, which could be bad news for new Carolina QB Baker Mayfield, who was mocked during and after his first game against the 49ers and now leads an even worse offense. By Eric Branch
- Nick Bosa urged his San Francisco 49ers teammates to play Monday night with the same intensity they did when they met the Rams in January with a trip to the Super Bowl on the line. By Eric Branch
- The San Francisco 49ers got everything they lacked before their Week 4 win over the Rams: big-play offense backed by overwhelming defense delivering drive-killing turnovers and sacks. By Michael Silver
- Deebo Samuel’s 57-yard touchdown catch was the signature play Monday night as the San Francisco 49ers hopped back to life with a 24-9 victory over the Los Angeles Rams. By Ron Kroichick
- The San Francisco 49ers delivered the kind of dominating win against the Rams that they might be used to, just a little earlier in 2022 than 2021. By Ann Killion
- The San Francisco 49ers had plenty of defense and just enough offense to beat the Rams on Monday night, calming nervous fans(if only for a week) and, on a technicality, moving into first place in the NFC West. By Michael Lerseth
- Golden State Warriors guard Stephen Curry indulged the Manning brothers during the San Francisco 49ers’ “Monday Night Football” romp, getting into his football-playing past and explaining why he’s actually kind of flashy. By Scott Ostler
- Nine months after strong safety Jaquiski Tartt dropped a gift-wrapped interception from Rams QB Mathew Stafford with the 49ers leading midway through the fourth quarter of their NFC Championship Game loss, Talanoa Hufanga — Tarrt’s replacement —... By Eric Branch
- San Francisco 49ers defensive tackle Javon Kinlaw, who has only played in seven of 22 games since Dec. 20, 2020, because of knee issues, won’t play Monday night against the Rams because of a knee injury. By Eric Branch
- The San Francisco 49ers took down the Los Angeles Rams with a 24-9 victory that featured big Niners plays on offense and seven sacks, two turnovers and a TD from the defense. By Chronicle staff
- Question everything. That mind-set, along with a tireless work ethic, has lifted San Francisco 49ers safety Talanoa Hufanga from fifth on the USC depth chart to the fifth-round of the NFL draft to a starting role in his second pro season. By Eric Branch
- San Francisco 49ers’ head coach Kyle Shanahan has dominated the Rams’ Sean McVay in head-to-head matchups, but McVay’s Super Bowl win tops everything else. They meet again Monday with the 49ers seeking a season turnaround. By Ann Killion
- When the 49ers stunned the Rams in November 2020, each coach was fed up with his starting quarterback and daydreaming about various replacement scenarios. Less than two years later, only one of them has managed to pull it off. By Michael Silver
- The Leals and Hartlaubs have been going to San Francisco 49ers games since 1947, but like many they’re finding that pro sports tickets, especially season tickets, are no longer a luxury middle-class families can afford. By Peter Hartlaub
- Head coach Kyle Shanahan said 49ers defensive tackle Javon Kinlaw was sidelined for the first two practices of the week because his knee was “flaring up on him.” Kinlaw underwent ACL reconstruction surgery last October. By Eric Branch
- With All-Pro Trent Williams sidelined, Colton McKivitz will again replace him against the Rams. Last season, with McKivitz pressed into action, the 49ers beat the Rams, 27-24, in overtime to secure the NFC’s final playoff spot. By Eric Branch
- After the San Francisco 49ers’ 11-10 loss in Denver, QB Jimmy Garoppolo cited his odd offseason for at least part of the offense’s poor performance. On Friday, Garoppolo was asked about accountability as a player. By Eric Branch
- It won’t be a surprise if San Francisco 49ers cornerback Deommodore Lenoir has an early wake-up call Monday. His task later that night will be lining up against Rams All-Pro wideout Cooper Kupp. By Eric Branch
- Rookie wide receiver Danny Gray might be able to jolt the San Francisco 49ers’ offense out of its doldrums, but that would require the ball to be thrown to him — something that has yet to happen. By Michael Silver
- San Francisco 49ers head coach Kyle Shanahan was asked Thursday about a social-media controversy involving Jimmy Garoppolo after the QB was captured yelling in frustration in a 11-10 loss in Denver on Sunday. By Eric Branch
- The San Francisco 49ers’ 1-2 start has inspired some harsh responses from readers. And a loss to the Rams on Monday night would give rise to this question: Can the 49ers overcome a stumbling start for a second straight season? By Eric Branch
- When San Francisco 49ers QB Jimmy Garoppolo accidentally stepped out of the back of the end zone for a safety Sunday night, it overshadowed this: He lost his composure on a play in which he lost his bearings. By Eric Branch
- The San Francisco 49ers likely will be without All-Pro left tackle Trent Williams for 4-6 weeks because of a high ankle sprain, head coach Kyle Shanahan told reporters Monday. By Eric Branch
- The San Francisco 49ers entered this year expecting big things from an offense loaded with talent, turned back to veteran QB Jimmy Garoppolo. After losing to the beatable Broncos, nobody should be so sure. By Michael Silver
- San Francisco 49ers’ All-Pro left tackle Trent Williams suffered a high ankle sprain when a defender was blocked into his right leg in the third quarter of Sunday’s 11-10 loss to the Broncos. By Eric Branch
- The San Francisco 49ers fell to 1-2 on the season despite playing strong defense against familiar foe Russell Wilson. Guess which unit didn’t do so well in Jimmy Garoppolo’s first start of the season? By Michael Lerseth
- The San Francisco 49ers losing a defensive battle to the Broncos and Russell Wilson doesn’t hide an offense struggling to get going under Jimmy Garoppolo and a team already beset by key injuries. By Ann Killion
- The San Francisco 49ers couldn’t survive a weak offensive effort and earn a win on defense after the Broncos’ fourth-quarter comeback behind Russell Wilson led to an 11-10 win that survived late Niners opportunities. By Eric Branch
- The San Francisco 49ers will face a formidable rushing attack without one of their best run-stuffers. Defensive tackle Arik Armstead is inactive for Sunday’s night meeting against the Broncos due to a foot injury. By Eric Branch
- Russell Wilson steered the Broncos to a hard-fought 11-10 win over the 49ers while Jimmy Garoppolo presided over an offense that committed a trio of turnovers to undermine a late comeback bid. By Chronicle Staff
- The San Francisco 49ers’ defense, off to a dominating start, draws a familiar foe Sunday in Russell Wilson, who is struggling with the Broncos. Could this set up some Niners vengeance, or will Wilson torment them yet again? By Michael Silver
- San Francisco 49ers QB Jimmy Garoppolo compared last Sunday’s relief win to his arrival on the team in 2017. Going up against the Broncos with tight end George Kittle back, he might get to sustain that free-flinging vibe. By Eric Branch
- San Francisco 49ers tight end George Kittle was officially cleared to play Friday after missing the season’s first two games with a groin injury and he’ll make his 2022 debut Sunday night against the Broncos, a team that inspires fond memories. By Eric Branch
- Guided by faith and the memory of a crushing setback that became a blessing, San Francisco 49ers linebackers coach Johnny Holland has maintained his trademark optimism during his three-year battle with cancer. By Eric Branch
- The San Francisco 49ers have lost their mobile quarterback for the season and are already running low on running backs. But they do have a healthy wide back, Deebo Samuel. By Eric Branch
- The early results from the San Francisco 49ers’ interior line are encouraging as the trio of right guard Spencer Burford, left guard Aaron Banks and center Jake Brendel have yet to allow a sack. By Eric Branch
- You can add booming voice to the list of attributes possessed by Jimmy Garoppolo, an asset that likely will come in handy when the San Francisco 49ers play at typically rowdy Denver on Sunday. By Eric Branch
- A month ago, the San Francisco 49ers didn’t see Jimmy Garoppolo in their plans for this season. But now, with Trey Lance out until 2023, Garoppolo is in a position of power and headed for a possible financial windfall. By Michael Silver
- 49ers game review: Five years later, the script was eerily similar Sunday for Jimmy Garoppolo as he came off the bench to take over as the San Francisco 49ers’ starting quarterback. By Eric Branch
- Two days after a broken ankle ended Trey Lance’s season, the San Francisco 49ers signed QB Kurt Benkert to their practice squad to serve as their de facto No. 3 behind Jimmy Garoppolo and rookie Brock Purdy, a league source said. By Eric Branch
- Dr. Kenneth Yung, a foot and ankle surgeon who is a consultant to the Los Angeles Rams, said the broken ankle suffered by 49ers quarterback Trey Lance, as it was described by the team in a statement Monday, could be fully healed within 10 to 12... By Eric Branch
- The season-ending broken ankle suffered by 49ers QB Trey Lance in their 27-7 win over the Seahawks on Sunday not only carries obvious short-term implications, but it also could have a potential longer-term impact at the position. By Eric Branch
- San Francisco 49ers QB Trey Lance had surgery Monday morning at Stanford Hospital to repair the broken ankle he suffered in the first quarter of Sunday’s 27-7 win over the Seahawks on Sunday. By Eric Branch
- San Francisco 49ers running back Ty Davis-Price suffered a high ankle sprain in a 27-7 win over Seattle on Sunday that will sideline him for a “few weeks,” head coach Kyle Shanahan said. By Eric Branch
- The San Francisco 49ers are about to reap the full benefit of retaining Jimmy Garoppolo, and there might be more than a few players happy that he’s back in action as their starting quarterback. By Michael Silver
- After Trey Lance suffered a season-ending broken ankle Sunday, the 49ers San Francisco 49ers went from having the NFL’s best backup QB, Jimmy Garoppolo, to perhaps its shakiest: rookie Brock Purdy, the 262nd and final pick of the 2022 draft. By Eric Branch
- When Trey Lance returns to the San Francisco 49ers next season, it might be wise for head coach Kyle Shanahan to modify the type of running plays he calls for the young quarterback. By Scott Ostler
- Disappointment over the San Francisco 49ers losing Trey Lance for the season in their 27-7 win over the Seahawks is mitigated by the knowledge that they’re turning to Jimmy Garoppolo, owner of their third-best record all-time. By Ann Killion
- With the loss of Trey Lance for the rest of the season in Sunday’s 27-7 throttling of Seattle, the future success of the San Francisco 49ers will be dictated by the steady hand of Jimmy Garoppolo and a shutdown defense. By Michael Lerseth
- Quarterback Trey Lance was carted off the field Sunday with an air cast on his right leg after he was injured late in the first quarter of the San Francisco 49ers’ game against the Seahawks at Levi’s Stadium. By Eric Branch
- The San Francisco 49ers earned their first win of the season, beating the Seattle Seahawks 27-7 behind QB Jimmy Garoppolo’s solid performance coming on in relief of injured starter Trey Lance. By Eric Branch, Eric Branch
- The San Francisco 49ers’ third-round picks will play in their first NFL game Sunday, but George Kittle’s 2022’s debut remains on hold. By Eric Branch
- Latest updates and analysis on the San Francisco 49ers as they overcame a season-ending injury to QB Trey Lance to beat the Seahawks behind backup Jimmy Garoppolo 27-7 in their home opener. By Chronicle Staff
- In one week, San Francisco 49ers quarterback Trey Lance apparently moved up from one of the worst current NFL QBs to one of the worst of all time. By Scott Ostler
- The San Francisco 49ers may not have to worry about Russell Wilson under center for the Seahawks, but Seattle just beat its former QB and Trey Lance will be trying to get the Niners in the win column on another rainy day. By Eric Branch
- The San Francisco 49ers listed George Kittle as questionable to play in Sunday’s home opener against the Seahawks, but the All-Pro tight end is considered unlikely to make his 2022 debut, according to a source. By Eric Branch
- Trey Lance’s first start for the San Francisco 49ers at home this season is a great opportunity to redeem himself after a lackluster initial loss, because the alternatives could amp up a real quarterback controversy. By Michael Silver
- San Francisco 49ers defensive tackle Javon Kinlaw finished Sunday’s season opener without a sack or a tackle, but more meaningful was that the oft-injured 2020 draft pick also ended the game without any pain. By Eric Branch
- The San Francisco 49ers will be without Elijah Mitchell for two months, but as Jeff Wilson steps in as the team’s lead running back, he has wisdom for rookie reserves Ty Davis-Price and Jordan Mason. By Eric Branch
- The San Francisco 49ers are pouring money into Santa Clara’s political races to solidify their control of the city, but companies owned by Stephen Ross of the Dolphins are backing Mayor Lisa Gillmor’s re-election campaign. By Lance Williams and Ron Kroichick