Mark Horowitz

All Publications

• A Fast Large-Integer Extended GCD Algorithm and Hardware Design for Verifiable Delay Functions and Modular Inversion Cryptology ePrint Archive Sreedhar, K., Horowitz, M., Torng, C. 2022
• Automating System Configuration CONFERENCE ON FORMAL METHODS IN COMPUTER-AIDED DESIGN–FMCAD 2021 Tsiskaridze, N., Strange, M., Mann, M., Sreedhar, K., Liu, Q., Horowitz, M., Barrett, C. 2021

  View details for DOI 10.48550/arXiv.2108.05987

• Online, Interactive Tool for Studying How Students Troubleshoot Circuits 2021 ASEE Virtual Annual Conference Fritz, A., Horowitz, M., Jha, A. 2021
• Compiling Halide Programs to Push-Memory Accelerators arXiv.org (https://arxiv.org/abs/2105.12858) Liu, Q., Huff, D., Setter, J., Strange, M., Feng, K., Sreedhar, K., Wang, Z., Zhang, K., Horowitz, M., Raina, P., Kjolstad, F. 2021
• Automated Design Space Exploration of CGRA Processing Element Architectures using Frequent Subgraph Analysis arXiv.org (https://arxiv.org/abs/2104.14155) Melchert, J., Feng, K., Donovick, C., Daly, R., Barrett, C., Horowitz, M., Hanrahan, P., Raina, P. 2021
• Enabling Reusable Physical Design Flows with Modular Flow Generators arXiv.org Carsello, A., Thomas, J., Nayak, A., Chen, P., Horowitz, M., Raina, P., Torng, C. 2021

  View details for DOI 10.48550/arXiv.2111.14535

• Fast Validation of Mixed-Signal SoCs IEEE Open Journal of the Solid-State Circuits Society Stanley, D., Wang, C., Kim, S., Herbst, S., Kim, J., Horowitz, M. 2021; 1: 184 - 195

  View details for DOI 10.1109/OJSSCS.2021.3122397

• fault: A Python Embedded Domain-Specific Language for Metaprogramming Portable Hardware Verification Components International Conference on Computer Aided Verification Truong, L., Herbst, S., Setaluri, R., Mann, M., Daly, R., Zhang, K., Donovick, C., Stanley, D., Horowitz, M., Barrett, C., Hanrahan, P. 2020

  View details for DOI 10.1007/978-3-030-53288-8_19

• Interstellar: Using Halide's Scheduling Language to Analyze DNN Accelerators Yang, X., Gao, M., Liu, Q., Setter, J., Pu, J., Nayak, A., Bell, S., Cao, K., Ha, H., Raina, P., Kozyrakis, C., Horowitz, M., ACM ASSOC COMPUTING MACHINERY. 2020: 369–83

  View details for DOI 10.1145/3373376.3378514

  View details for Web of Science ID 000541369300024

• 20-GS/s 8-bit Analog-to-Digital Converter and 5-GHz Phase Interpolator for Open-Source Synthesizable High-Speed Link Applications IEEE Solid-State Circuits Letters Kim, S., Myers, Z., Herbst, S., Lim, B., Horowitz, M. 2020; 3: 518 - 521

  View details for DOI 10.1109/LSSC.2020.3037823

• SegAlign: A Scalable GPU-Based Whole Genome Aligner International Conference for High Performance Computing, Networking, Storage and Analysis (SC) Goenka, S., Turakhia, Y., Paten, B., Horowitz, M. 2020: 540–552

  View details for DOI 10.1109/SC41405.2020.00043

• Creating an Agile Hardware Design Flow 2020 57th ACM/IEEE Design Automation Conference (DAC) Bahr, R., Barrett, C., Bhagdikar, N., Carsello, A., Daly, R., Donovick, C., Durst, D., Fatahalian, K., Feng, K., Hanrahan, P., Hofstee, T., Horowitz, M., Huff, D., Kjolstad, F., Kong, T., Liu, Q., Mann, M., Melchert, J., Nayak, A., Niemetz, A., Nyengele, G., Raina, P., Richardson, S., Setaluri, R., Setter, J., et al 2020

  View details for DOI 10.1109/DAC18072.2020.9218553

• A Framework for Adding Low-Overhead, Fine-Grained Power Domains to CGRAs Nayak, A., Zhang, K., Setaluri, R., Carsello, A., Mann, M., Richardson, S., Bahr, R., Hanrahan, P., Horowitz, M., Raina, P. Design, Automation and Test in Europe Conference (DATE). 2020
• Open-Source Synthesizable Analog Blocks for High-Speed Link Designs: 20-GS/s 5b ENOB Analog-to-Digital Converter and 5-GHz Phase Interpolator 2020 IEEE Symposium on VLSI Circuits Kim, S., Myers, Z., Herbst, S., Lim, B., Horowitz, M. 2020

  View details for DOI 10.1109/VLSICircuits18222.2020.9162800

• An Analog Model Template Library: Simplifying Chip-Level, Mixed-Signal Design Verification IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS Lim, B., Horowitz, M. 2019; 27 (1): 193–204

  View details for DOI 10.1109/TVLSI.2018.2873387

  View details for Web of Science ID 000455117600019

• TANGRAM: Optimized Coarse-Grained Dataflow for Scalable NN Accelerators ASPLOS '19: Proceedings of the Twenty-Fourth International Conference on Architectural Support for Programming Languages and Operating Systems Gao, M., Yang, X., Pu, J., Horowitz, M., Kozyrakis, C. 2019: 807–20

  View details for DOI 10.1145/3297858.3304014

• StartupBR: Higher Education's Influence on Social Networks and Entrepreneurship in Brazil arXiv:1904.12026 Reddy, M., Nardelli, J. C., Pereira, Y. L., Vasconcelos, M., Silva, T. H., Oliveira, L. B., Horowitz, M. 2019
• DATASET CULLING: TOWARDS EFFICIENT TRAINING OF DISTILLATION-BASED DOMAIN SPECIFIC MODELS Yoshioka, K., Lee, E., Wong, S., Horowitz, M., IEEE IEEE. 2019: 3237–41

  View details for Web of Science ID 000521828603075

• Trapped Ion Quantum Computers QUANTUM COMPUTING: PROGRESS AND PROSPECTS Grumbling, E., Horowitz, M., Comm Tech Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies Boa, Div Engn Phys Sci, Natl Acad Sci Engn Med, Grumbling, E., Horowitz, M. 2019: 196–204

  View details for Web of Science ID 000574896500011

• Feasibility and Time Frames of Quantum Computing QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 156–92

  View details for Web of Science ID 000574896500009

• Progress in Computing QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 12–23

  View details for Web of Science ID 000574896500003

• QUANTUM COMPUTING Progress and Prospects Preface QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Tech Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: XI-XV

  View details for Web of Science ID 000574896500001

• Superconducting Quantum Computers QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 205–11

  View details for Web of Science ID 000574896500012

• Quantum Computing's Implications for Cryptography QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 95–112

  View details for Web of Science ID 000574896500006

• Quantum Algorithms and Applications QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 57–94

  View details for Web of Science ID 000574896500005

• QUANTUM COMPUTING Progress and Prospects Summary QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Tech Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 1–11

  View details for Web of Science ID 000574896500002

• Other Approaches to Building Qubits QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 212–25

  View details for Web of Science ID 000574896500013

• Statement of Task QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 195

  View details for Web of Science ID 000574896500010

• Essential Hardware Components of a Quantum Computer QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 113–34

  View details for Web of Science ID 000574896500007

• Essential Software Components of a Scalable Quantum Computer QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 135–55

  View details for Web of Science ID 000574896500008

• Global R&D Investment QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 226–29

  View details for Web of Science ID 000574896500014

• Quantum Computing: A New Paradigm QUANTUM COMPUTING: PROGRESS AND PROSPECTS Horowitz, M. A., Aspuru-Guzik, A., Awschalom, D. D., Blakley, B., Boneh, D., Coppersmith, S. N., Kim, J., Martinis, J. M., Martonosi, M., Mosca, M., Oliver, W. D., Svore, K., Vazirani, U. V., Jahanian, F., Barroso, L., Bellovin, S. M., Brammer, R. F., Culler, D., Frank, E., Haas, L., Horowitz, M., Horvitz, E., Kumar, V., Mynatt, B., Partridge, C., Rus, D., Schneider, F. B., Seltzer, M., Vardi, M., Comm Techn Assessment Feasibility, Comp Sci Telecommun Board, Intelligence Community Studies, Div Engn Phys Sci, Natl Acad Sci, Natl Acad Engn, Natl Acad Med, Grumbling, E., Horowitz, M. 2019: 24–56

  View details for Web of Science ID 000574896500004

• Falcon — A Flexible Architecture For Accelerating Cryptography 2019 IEEE 16th International Conference on Mobile Ad Hoc and Sensor Systems (MASS) Kiningham, K., Levis, P., Anderson, M., Boneh, D., Horowitz, M., Shih, M. 2019

  View details for DOI 10.1109/MASS.2019.00025

• Mapping Histological Slice Sequences to the Allen Mouse Brain Atlas Without 3D Reconstruction. Frontiers in neuroinformatics Xiong, J., Ren, J., Luo, L., Horowitz, M. 2018; 12: 93

  Abstract

  Histological brain slices are widely used in neuroscience to study the anatomical organization of neural circuits. Systematic and accurate comparisons of anatomical data from multiple brains, especially from different studies, can benefit tremendously from registering histological slices onto a common reference atlas. Most existing methods rely on an initial reconstruction of the volume before registering it to a reference atlas. Because these slices are prone to distortions during the sectioning process and often sectioned with non-standard angles, reconstruction is challenging and often inaccurate. Here we describe a framework that maps each slice to its corresponding plane in the Allen Mouse Brain Atlas (2015) to build a plane-wise mapping and then perform 2D nonrigid registration to build a pixel-wise mapping. We use the L2 norm of the histogram of oriented gradients difference of two patches as the similarity metric for both steps and a Markov random field formulation that incorporates tissue coherency to compute the nonrigid registration. To fix significantly distorted regions that are misshaped or much smaller than the control grids, we train a context-aggregation network to segment and warp them to their corresponding regions with thin plate spline. We have shown that our method generates results comparable to an expert neuroscientist and is significantly better than reconstruction-first approaches. Code and sample dataset are available at sites.google.com/view/brain-mapping.

  View details for DOI 10.3389/fninf.2018.00093

  View details for PubMedID 30618698

  View details for PubMedCentralID PMC6297281

• Mapping Histological Slice Sequences to the Allen Mouse Brain Atlas Without 3D Reconstruction FRONTIERS IN NEUROINFORMATICS Xiong, J., Ren, J., Luo, L., Horowitz, M. 2018; 12

  View details for DOI 10.3389/fninf.2018.00093

  View details for Web of Science ID 000452913600001

• The Interaction Engine DESIGN THINKING RESEARCH: MAKING DISTINCTIONS: COLLABORATION VERSUS COOPERATION Martelaro, N., Ju, W., Horowitz, M., Plattner, H., Meinel, C., Leifer, L. 2018: 147–69

  View details for DOI 10.1007/978-3-319-60967-6_8

  View details for Web of Science ID 000432741300009

• Tethys: Collecting Sensor Data without Infrastracture or Trust 2018 IEEE/ACM Third International Conference on Internet-of-Things Design and Implementation (IoTDI) Chiang, H., Hong, J., Kiningham, K., Riliskis, L., Levis, P., Horowitz, M. 2018: 249–54

  View details for DOI 10.1109/IoTDI.2018.00032

• Rethinking Non-major Circuits Pedagogy for Improved Motivation Bell, S., Horowitz, M. 2018 ASEE Annual Conference & Exposition (https://peer.asee.org/30936). 2018
• DNN Dataflow Choice Is Overrated arXiv:1809.04070 Yang, X., Gao, M., Pu, J., Nayak, A., Liu, Q., Bell, S. E., Setter, J. O., Cao, K., Ha, H., Kozyrakis, C., Horowitz, M. 2018
• Training Domain Specific Models for Energy-Efficient Object Detection arXiv:1811.02689 Yoshioka, K., Lee, E., Horowitz, M. 2018
• Compiling Algorithms for Heterogeneous Systems Synthesis Lectures on Computer Architecture Bell, S., Pu, J., Hegarty, J., Horowitz, M. 2018: 105

  View details for DOI 10.2200/S00816ED1V01Y201711CAC043

• Mapping Mouse Brain Slice Sequence to a Reference Brain Without 3D Reconstruction bioRxiv Xiong, J., Ren, J., Luo, L., Horowitz, M. 2018

  View details for DOI 10.1101/357475

• Fast FPGA Emulation of Analog Dynamics in Digitally-Driven Systems Herbst, S., Lim, B., Horowitz, M., Assoc Comp Machinery ASSOC COMPUTING MACHINERY. 2018

  View details for DOI 10.1145/3240765.3240808

  View details for Web of Science ID 000494640800129

• Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems. Cell Ren, J. n., Friedmann, D. n., Xiong, J. n., Liu, C. D., Ferguson, B. R., Weerakkody, T. n., DeLoach, K. E., Ran, C. n., Pun, A. n., Sun, Y. n., Weissbourd, B. n., Neve, R. L., Huguenard, J. n., Horowitz, M. A., Luo, L. n. 2018

  Abstract

  The dorsal raphe (DR) constitutes a major serotonergic input to the forebrain and modulates diverse functions and brain states, including mood, anxiety, and sensory and motor functions. Most functional studies to date have treated DR serotonin neurons as a single population. Using viral-genetic methods, we found that subcortical- and cortical-projecting serotonin neurons have distinct cell-body distributions within the DR and differentially co-express a vesicular glutamate transporter. Further, amygdala- and frontal-cortex-projecting DR serotonin neurons have largely complementary whole-brain collateralization patterns, receive biased inputs from presynaptic partners, and exhibit opposite responses to aversive stimuli. Gain- and loss-of-function experiments suggest that amygdala-projecting DR serotonin neurons promote anxiety-like behavior, whereas frontal-cortex-projecting neurons promote active coping in the face of challenge. These results provide compelling evidence that the DR serotonin system contains parallel sub-systems that differ in input and output connectivity, physiological response properties, and behavioral functions.

  View details for PubMedID 30146164

• Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform. ACS synthetic biology Madison, A. C., Royal, M. W., Vigneault, F., Chen, L., Griffin, P. B., Horowitz, M., Church, G. M., Fair, R. B. 2017; 6 (9): 1701-1709

  Abstract

  Electrowetting-on-dielectric (EWD) digital microfluidic laboratory-on-a-chip platforms demonstrate excellent performance in automating labor-intensive protocols. When coupled with an on-chip electroporation capability, these systems hold promise for streamlining cumbersome processes such as multiplex automated genome engineering (MAGE). We integrated a single Ti:Au electroporation electrode into an otherwise standard parallel-plate EWD geometry to enable high-efficiency transformation of Escherichia coli with reporter plasmid DNA in a 200 nL droplet. Test devices exhibited robust operation with more than 10 transformation experiments performed per device without cross-contamination or failure. Despite intrinsic electric-field nonuniformity present in the EP/EWD device, the peak on-chip transformation efficiency was measured to be 8.6 ± 1.0 × 108 cfu·μg-1 for an average applied electric field strength of 2.25 ± 0.50 kV·mm-1. Cell survival and transformation fractions at this electroporation pulse strength were found to be 1.5 ± 0.3 and 2.3 ± 0.1%, respectively. Our work expands the EWD toolkit to include on-chip microbial electroporation and opens the possibility of scaling advanced genome engineering methods, like MAGE, into the submicroliter regime.

  View details for DOI 10.1021/acssynbio.7b00007

  View details for PubMedID 28569062

• Programming Heterogeneous Systems from an Image Processing DSL ACM TRANSACTIONS ON ARCHITECTURE AND CODE OPTIMIZATION Pu, J., Bell, S., Yang, X., Setter, J., Richardson, S., Ragan-Kelley, J., Horowitz, M. 2017; 14 (3)

  View details for DOI 10.1145/3107953

  View details for Web of Science ID 000423744000006

• Dynamic structure of locomotor behavior in walking fruit flies ELIFE Katsov, A. Y., Freifeld, L., Horowitz, M., Kuehn, S., Clandinin, T. R. 2017; 6

  Abstract

  The function of the brain is unlikely to be understood without an accurate description of its output, yet the nature of movement elements and their organization remains an open problem. Here, movement elements are identified from dynamics of walking in flies, using unbiased criteria. On one time scale, dynamics of walking are consistent over hundreds of milliseconds, allowing elementary features to be defined. Over longer periods, walking is well described by a stochastic process composed of these elementary features, and a generative model of this process reproduces individual behavior sequences accurately over seconds or longer. Within elementary features, velocities diverge, suggesting that dynamical stability of movement elements is a weak behavioral constraint. Rather, long-term instability can be limited by the finite memory between these elementary features. This structure suggests how complex dynamics may arise in biological systems from elements whose combination need not be tuned for dynamic stability.

  View details for PubMedID 28742018

• Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples ELIFE Yu, F., Blainey, P. C., Schulz, F., Woyke, T., Horowitz, M. A., Quake, S. R. 2017; 6

  Abstract

  Metagenomics and single-cell genomics have enabled genome discovery from unknown branches of life. However, extracting novel genomes from complex mixtures of metagenomic data can still be challenging and represents an ill-posed problem which is generally approached with ad hoc methods. Here we present a microfluidic-based mini-metagenomic method which offers a statistically rigorous approach to extract novel microbial genomes while preserving single-cell resolution. We used this approach to analyze two hot spring samples from Yellowstone National Park and extracted 29 new genomes, including three deeply branching lineages. The single-cell resolution enabled accurate quantification of genome function and abundance, down to 1% in relative abundance. Our analyses of genome level SNP distributions also revealed low to moderate environmental selection. The scale, resolution, and statistical power of microfluidic-based mini-metagenomics make it a powerful tool to dissect the genomic structure of microbial communities while effectively preserving the fundamental unit of biology, the single cell.

  View details for PubMedID 28678007

• Why Design Must Change: Rethinking Digital Design Micro, IEEE Shacham, O., Azizi, O., Wachs, M., Richardson, S., Horowitz, M. ; PP (99): 1-1

  View details for DOI 10.1109/MM.2010.81

• Measurement of Supply Pin Current Distributions in Integrated Circuit Packages Weaver, James, A., Horowitz, Mark, A.
• Analyzing CMOS Power Supply Networks Using Ariel, ACM/IEEE Stark, D., Horowitz, M.
• Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution NATURE COMMUNICATIONS Yogev, S., Maeder, C. I., Cooper, R., Horowitz, M., Hendricks, A. G., Shen, K. 2017; 8

  Abstract

  Abnormal axonal transport is associated with neuronal disease. We identified a role for DHC-1, the C. elegans dynein heavy chain, in maintaining neuronal cargo distribution. Surprisingly, this does not involve dynein's role as a retrograde motor in cargo transport, hinging instead on its ability to inhibit microtubule (MT) dynamics. Neuronal MTs are highly static, yet the mechanisms and functional significance of this property are not well understood. In disease-mimicking dhc-1 alleles, excessive MT growth and collapse occur at the dendrite tip, resulting in the formation of aberrant MT loops. These unstable MTs act as cargo traps, leading to ectopic accumulations of cargo and reduced availability of cargo at normal locations. Our data suggest that an anchored dynein pool interacts with plus-end-out MTs to stabilize MTs and allow efficient retrograde transport. These results identify functional significance for neuronal MT stability and suggest a mechanism for cellular dysfunction in dynein-linked disease.

  View details for DOI 10.1038/ncomms15063

  View details for Web of Science ID 000399053800001

  View details for PubMedID 28406181

• Dark Memory and Accelerator-Rich System Optimization in the Dark Silicon Era IEEE DESIGN & TEST Pedram, A., Richardson, S., Horowitz, M., Galal, S., Kvatinsky, S. 2017; 34 (2): 39-50

  View details for DOI 10.1109/MDAT.2016.2573586

  View details for Web of Science ID 000396240300006

• TETRIS: Scalable and Efficient Neural Network Acceleration with 3D Memory ACM SIGPLAN NOTICES Gao, M., Pu, J., Yang, X., Horowitz, M., Kozyrakis, C. 2017; 52 (4): 751-764

  View details for DOI 10.1145/3037697.3037702

  View details for Web of Science ID 000401540000053

• Long-term microfluidic tracking of coccoid cyanobacterial cells reveals robust control of division timing BMC BIOLOGY Yu, F. B., Willis, L., Chau, R. M., Zambon, A., Horowitz, M., Bhaya, D., Huang, K. C., Quake, S. R. 2017; 15

  Abstract

  Cyanobacteria are important agents in global carbon and nitrogen cycling and hold great promise for biotechnological applications. Model organisms such as Synechocystis sp. and Synechococcus sp. have advanced our understanding of photosynthetic capacity and circadian behavior, mostly using population-level measurements in which the behavior of individuals cannot be monitored. Synechocystis sp. cells are small and divide slowly, requiring long-term experiments to track single cells. Thus, the cumulative effects of drift over long periods can cause difficulties in monitoring and quantifying cell growth and division dynamics.To overcome this challenge, we enhanced a microfluidic cell-culture device and developed an image analysis pipeline for robust lineage reconstruction. This allowed simultaneous tracking of many cells over multiple generations, and revealed that cells expand exponentially throughout their cell cycle. Generation times were highly correlated for sister cells, but not between mother and daughter cells. Relationships between birth size, division size, and generation time indicated that cell-size control was inconsistent with the "sizer" rule, where division timing is based on cell size, or the "timer" rule, where division occurs after a fixed time interval. Instead, single cell growth statistics were most consistent with the "adder" rule, in which division occurs after a constant increment in cell volume. Cells exposed to light-dark cycles exhibited growth and division only during the light period; dark phases pause but do not disrupt cell-cycle control.Our analyses revealed that the "adder" model can explain both the growth-related statistics of single Synechocystis cells and the correlation between sister cell generation times. We also observed rapid phenotypic response to light-dark transitions at the single cell level, highlighting the critical role of light in cyanobacterial cell-cycle control. Our findings suggest that by monitoring the growth kinetics of individual cells we can build testable models of circadian control of the cell cycle in cyanobacteria.

  View details for DOI 10.1186/s12915-016-0344-4

  View details for Web of Science ID 000394057800001

  View details for PubMedID 28196492

• Microtubule Organization Determines Axonal Transport Dynamics. Neuron Yogev, S., Cooper, R., Fetter, R., Horowitz, M., Shen, K. 2016; 92 (2): 449-460

  Abstract

  Axonal microtubule (MT) arrays are the major cytoskeleton substrate for cargo transport. How MT organization, i.e., polymer length, number, and minus-end spacing, is regulated and how it impinges on axonal transport are unclear. We describe a method for analyzing neuronal MT organization using light microscopy. This method circumvents the need for electron microscopy reconstructions and is compatible with live imaging of cargo transport and MT dynamics. Examination of a C. elegans motor neuron revealed how age, MT-associated proteins, and signaling pathways control MT length, minus-end spacing, and coverage. In turn, MT organization determines axonal transport progression: cargoes pause at polymer termini, suggesting that switching MT tracks is rate limiting for efficient transport. Cargo run length is set by MT length, and higher MT coverage correlates with shorter pauses. These results uncover the principles and mechanisms of neuronal MT organization and its regulation of axonal cargo transport.

  View details for DOI 10.1016/j.neuron.2016.09.036

  View details for PubMedID 27764672

• Rigel: Flexible Multi-Rate Image Processing Hardware ACM TRANSACTIONS ON GRAPHICS Hegarty, J., Daly, R., DeVito, Z., Ragan-Kelley, J., Horowitz, M., Hanrahan, P. 2016; 35 (4)

  View details for DOI 10.1145/2897824.2925892

  View details for Web of Science ID 000380112400055

• Tomographic Reconstruction and Alignment Using Matrix Norm Minimization IEEE JOURNAL OF SELECTED TOPICS IN SIGNAL PROCESSING Song, K., Horowitz, M. 2016; 10 (1): 47-60

  View details for DOI 10.1109/JSTSP.2015.2510163

  View details for Web of Science ID 000369495900004

• Error Control and Limit Cycle Elimination in Event-Driven Piecewise Linear Analog Functional Models IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS Lim, B. C., Horowitz, M. 2016; 63 (1): 23-33

  View details for DOI 10.1109/TCSI.2015.2512699

  View details for Web of Science ID 000372001500003

• Convolution Engine: Balancing Efficiency and Flexibility in Specialized Computing COMMUNICATIONS OF THE ACM Qadeer, W., Hameed, R., Shacham, O., Venkatesan, P., Kozyrakis, C., Horowitz, M. 2015; 58 (4): 85-93

  View details for DOI 10.1145/2735841

  View details for Web of Science ID 000351734500024

• Building Conflict-Free FFT Schedules IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS Richardson, S., Markovic, D., Danowitz, A., Brunhaver, J., Horowitz, M. 2015; 62 (4): 1146-1155

  View details for DOI 10.1109/TCSI.2015.2402935

  View details for Web of Science ID 000352288800024

• Digital Analog Design: Enabling Mixed-Signal System Validation IEEE DESIGN & TEST Lim, B. C., Mao, J., Horowitz, M., Jang, J., Kim, J. 2015; 32 (1): 44-52

  View details for DOI 10.1109/MDAT.2014.2361718

  View details for Web of Science ID 000348097200007

• Enhancing the performance of the light field microscope using wavefront coding OPTICS EXPRESS Cohen, N., Yang, S., Andalman, A., Broxton, M., Grosenick, L., Deisseroth, K., Horowitz, M., Levoy, M. 2014; 22 (20): 24817-24839

  Abstract

  Light field microscopy has been proposed as a new high-speed volumetric computational imaging method that enables reconstruction of 3-D volumes from captured projections of the 4-D light field. Recently, a detailed physical optics model of the light field microscope has been derived, which led to the development of a deconvolution algorithm that reconstructs 3-D volumes with high spatial resolution. However, the spatial resolution of the reconstructions has been shown to be non-uniform across depth, with some z planes showing high resolution and others, particularly at the center of the imaged volume, showing very low resolution. In this paper, we enhance the performance of the light field microscope using wavefront coding techniques. By including phase masks in the optical path of the microscope we are able to address this non-uniform resolution limitation. We have also found that superior control over the performance of the light field microscope can be achieved by using two phase masks rather than one, placed at the objective's back focal plane and at the microscope's native image plane. We present an extended optical model for our wavefront coded light field microscope and develop a performance metric based on Fisher information, which we use to choose adequate phase masks parameters. We validate our approach using both simulated data and experimental resolution measurements of a USAF 1951 resolution target; and demonstrate the utility for biological applications with in vivo volumetric calcium imaging of larval zebrafish brain.

  View details for DOI 10.1364/OE.22.024817

  View details for Web of Science ID 000342757000104

  View details for PubMedCentralID PMC4247191

• A Verilog Piecewise-Linear Analog Behavior Model for Mixed-Signal Validation IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS Liao, S., Horowitz, M. 2014; 61 (8): 2229-2235

  View details for DOI 10.1109/TCSI.2014.2332265

  View details for Web of Science ID 000341593000003

• Darkroom: Compiling High-Level Image Processing Code into Hardware Pipelines ACM TRANSACTIONS ON GRAPHICS Hegarty, J., Brunhaver, J., DeVito, Z., Ragan-Kelley, J., Cohen, N., Bell, S., Vasilyev, A., Horowitz, M., Hanrahan, P. 2014; 33 (4)

  View details for DOI 10.1145/2601097.2601174

  View details for Web of Science ID 000340000100111

• Large-scale mapping of transposable element insertion sites using digital encoding of sample identity. Genetics Gohl, D. M., Freifeld, L., Silies, M., Hwa, J. J., Horowitz, M., Clandinin, T. R. 2014; 196 (3): 615-623

  Abstract

  Determining the genomic locations of transposable elements is a common experimental goal. When mapping large collections of transposon insertions, individualized amplification and sequencing is both time consuming and costly. We describe an approach in which large numbers of insertion lines can be simultaneously mapped in a single DNA sequencing reaction by using digital error-correcting codes to encode line identity in a unique set of barcoded pools.

  View details for DOI 10.1534/genetics.113.159483

  View details for PubMedID 24374352

  View details for PubMedCentralID PMC3948795

• Large-scale mapping of transposable element insertion sites using digital encoding of sample identity. Genetics Gohl, D. M., Freifeld, L., Silies, M., Hwa, J. J., Horowitz, M., Clandinin, T. R. 2014; 196 (3): 615-623

  View details for DOI 10.1534/genetics.113.159483

  View details for PubMedID 24374352

• Forwarding Metamorphosis: Fast Programmable Match-Action Processing in Hardware for SDN SIGCOMM Conference Bosshart, P., Gibb, G., Kim, H., Varghese, G., McKeown, N., Izzard, M., Mujica, F., Horowitz, M. ASSOC COMPUTING MACHINERY. 2013: 99–110

  View details for DOI 10.1145/2534169.2486011

  View details for Web of Science ID 000327465900016

• GABAergic Lateral Interactions Tune the Early Stages of Visual Processing in Drosophila NEURON Freifeld, L., Clark, D. A., Schnitzer, M. J., Horowitz, M. A., Clandinin, T. R. 2013; 78 (6): 1075-1089

  Abstract

  Early stages of visual processing must capture complex, dynamic inputs. While peripheral neurons often implement efficient encoding by exploiting natural stimulus statistics, downstream neurons are specialized to extract behaviorally relevant features. How do these specializations arise? We use two-photon imaging in Drosophila to characterize a first-order interneuron, L2, that provides input to a pathway specialized for detecting moving dark edges. GABAergic interactions, mediated in part presynaptically, create an antagonistic and anisotropic center-surround receptive field. This receptive field is spatiotemporally coupled, applying differential temporal processing to large and small dark objects, achieving significant specialization. GABAergic circuits also mediate OFF responses and balance these with responses to ON stimuli. Remarkably, the functional properties of L2 are strikingly similar to those of bipolar cells, yet emerge through different molecular and circuit mechanisms. Thus, evolution appears to have converged on a common strategy for processing visual information at the first synapse.

  View details for DOI 10.1016/j.neuron.2013.04.024

  View details for Web of Science ID 000321026900013

  View details for PubMedID 23791198

  View details for PubMedCentralID PMC3694283

• Microfluidic serial digital to analog pressure converter for arbitrary pressure generation and contamination-free flow control LAB ON A CHIP Yu, F., Horowitz, M. A., Quake, S. R. 2013; 13 (10): 1911-1918

  Abstract

  Multilayer microfluidics based on PDMS (polydimethylsiloxane) soft lithography have offered parallelism and integration for biological and chemical sciences, where reduction in reaction volume and consistency of controlled variables across experiments translate into reduced cost, increased quantity and quality of data. One issue with push up or push down microfluidic control concept is the inability to provide multiple control pressures without adding more complex and expensive external pressure controls. We present here a microfluidic serial DAC (Digital to Analog Converter) that can be integrated with any PDMS device to expand the device's functionality by effectively adding an on-chip pressure regulator. The microfluidic serial DAC can be used with any incompressible fluids and operates in a similar fashion compared to an electronic serial DAC. It can be easily incorporated into any existing multilayer microfluidic devices, and the output pressure that the device generates could be held for extensive times. We explore in this paper various factors that affect resolution, speed, and linearity of the DAC output. As an application, we demonstrate microfluidic DAC's ability for on-chip manipulation of flow resistance when integrated with a simple flow network. In addition, we illustrate an added advantage of using the microfluidic serial DAC in preventing back flow and possible contamination.

  View details for DOI 10.1039/c3lc41394b

  View details for Web of Science ID 000317937300011

  View details for PubMedID 23529280

• A Verilog Piecewise-Linear Analog Behavior Model for Mixed-Signal Validation 35th Annual IEEE Custom Integrated Circuits Conference (CICC) - The Showcase for Circuit Design in the Heart of Silicon Valley Liao, S., Horowitz, M. IEEE. 2013

  View details for Web of Science ID 000350887800060

• Design Principles for Packet Parsers 9th ACM/IEEE Symposium on Architectures for Networking and Communications Systems (ANCS) Gibb, G., Varghese, G., Horowitz, M., McKeown, N. IEEE. 2013: 13–24

  View details for Web of Science ID 000345909600002

• An Area-Efficient Minimum-Time FFT Schedule Using Single-Ported Memory IFIP/IEEE 21st International Conference on Very Large Scale Integration (VLSI-SoC) Richardson, S., Shacham, O., Markovic, D., Horowitz, M. IEEE. 2013: 39–44

  View details for Web of Science ID 000332046100008

• FPU Generator for Design Space Exploration 21st IEEE Symposium on Computer Arithmetic (ARITH) Galal, S., Shacham, O., Brunhaver, J. S., Pu, J., Vassiliev, A., Horowitz, M. IEEE. 2013: 25–34

  View details for DOI 10.1109/ARITH.2013.27

  View details for Web of Science ID 000326337100004

• The Frankencamera: An Experimental Platform for Computational Photography COMMUNICATIONS OF THE ACM Adams, A., Jacobs, D. E., Dolson, J., Tico, M., Pulli, K., Talvala, E., Ajdin, B., Vaquero, D., Lensch, H. P., Horowitz, M., Park, S. H., Gelfand, N., Baek, J., Matusik, W., Levoy, M. 2012; 55 (11): 90-98

  View details for DOI 10.1145/2366316.2366339

  View details for Web of Science ID 000311293300029

• Bringing Up a Chip on the Cheap IEEE DESIGN & TEST OF COMPUTERS Wachs, M., Shacham, O., Asgar, Z., Firoozshahian, A., Richardson, S., Horowitz, M. 2012; 29 (6): 57-65

  View details for DOI 10.1109/MDT.2011.2179849

  View details for Web of Science ID 000318544300008

• Removing high contrast artifacts via digital inpainting in cryo-electron tomography: An application of compressed sensing JOURNAL OF STRUCTURAL BIOLOGY Song, K., Comolli, L. R., Horowitz, M. 2012; 178 (2): 108-120

  Abstract

  To cope with poor quality in cryo-electron tomography images, electron-dense markers, such as colloidal goldbeads, are often used to assist image registration and analysis algorithms. However, these markers can create artifacts that occlude a specimen due to their high contrast, which can also cause failure of some image processing algorithms. One way of reducing these artifacts is to replace high contrast objects with pixel densities that blend into the surroundings in the projection domain before volume reconstruction. In this paper, we propose digital inpainting via compressed sensing (CS) as a new method to achieve this goal. We show that cryo-ET projections are sparse in the discrete cosine transform (DCT) domain, and, by finding the sparsest DCT domain decompositions given uncorrupted pixels, we can fill in the missing pixel values that are occluded by high contrast objects without discontinuities. Our method reduces visual artifacts both in projections and in tomograms better than conventional algorithms, such as polynomial interpolation and random noise inpainting.

  View details for DOI 10.1016/j.jsb.2012.01.003

  View details for Web of Science ID 000304287400006

  View details for PubMedID 22248454

• CMOS Image Sensors With Multi-Bucket Pixels for Computational Photography IEEE JOURNAL OF SOLID-STATE CIRCUITS Wan, G., Li, X., Agranov, G., Levoy, M., Horowitz, M. 2012; 47 (4): 1031-1042

  View details for DOI 10.1109/JSSC.2012.2185189

  View details for Web of Science ID 000302494700022

• CPU DB: Recording Microprocessor History COMMUNICATIONS OF THE ACM Danowitz, A., Kelley, K., Mao, J., Stevenson, J. P., Horowitz, M. 2012; 55 (4): 55-63

  View details for DOI 10.1145/2133806.2133822

  View details for Web of Science ID 000302915000023

• Avoiding Game Over: Bringing Design to the Next Level 49th ACM/EDAC/IEEE Design Automation Conference (DAC) Shacham, O., Galal, S., Sankaranarayanan, S., Wachs, M., Brunhaver, J., Vassiliev, A., Horowitz, M., Danowitz, A., Qadeer, W., Richardson, S. IEEE. 2012: 623–629

  View details for Web of Science ID 000309256800089

• A New IC with Level-Crossing ADC Readout Architecture for PET Detector Signals IEEE Nuclear Science Symposium / Medical Imaging Conference Record (NSS/MIC) / 19th Room-Temperature Semiconductor X-ray and Gamma-ray Detector Workshop Lau, F. W., Choi, H. H., Horowitz, M. A., Levin, C. S. IEEE. 2012: 2486–2488

  View details for Web of Science ID 000326814202127

• Design Automation Framework for Application-Specific Logic-in-Memory Blocks 23rd IEEE International Conference on Application-Specific Systems, Architectures and Processors (ASAP) Zhu, Q., Vaidyanathan, K., Shacham, O., Horowitz, M., Pileggi, L., Franchetti, F. IEEE. 2012: 125–132

  View details for Web of Science ID 000312737700018

• Rethinking DRAM Power Modes for Energy Proportionality 45th IEEE/ACM Annual International Symposium on Microarchitecture (MICRO) Malladi, K. T., Shaeffer, I., Gopalakrishnan, L., Lo, D., Lee, B. C., Horowitz, M. IEEE COMPUTER SOC. 2012: 131–142

  View details for DOI 10.1109/MICRO.2012.21

  View details for Web of Science ID 000319333900012

• Removing Overhead From High-Level Interfaces 49th ACM/EDAC/IEEE Design Automation Conference (DAC) Kelly, K., Wachs, M., Stevenson, J., Richardson, S., Horowitz, M. IEEE. 2012: 783–789

  View details for Web of Science ID 000309256800112

• Towards Energy-Proportional Datacenter Memory with Mobile DRAM 39th Annual International Symposium on Computer Architecture (ISCA) Malladi, K. T., Nothaft, F. A., Periyathambi, K., Lee, B. C., Kozyrakis, C., Horowitz, M. IEEE. 2012: 37–48

  View details for Web of Science ID 000309010000004

• Understanding Sources of Inefficiency in General-Purpose Chips COMMUNICATIONS OF THE ACM Hameed, R., Qadeer, W., Wachs, M., Azizi, O., Solomatnikov, A., Lee, B. C., Richardson, S., Kozyrakis, C., Horowitz, M. 2011; 54 (10): 85-93

  View details for DOI 10.1145/2001269.2001291

  View details for Web of Science ID 000296022500021

• Energy-Efficient Floating-Point Unit Design IEEE TRANSACTIONS ON COMPUTERS Galal, S., Horowitz, M. 2011; 60 (7): 913-922

  View details for DOI 10.1109/TC.2010.121

  View details for Web of Science ID 000290867300001

• Defining the Computational Structure of the Motion Detector in Drosophila NEURON Clark, D. A., Bursztyn, L., Horowitz, M. A., Schnitzer, M. J., Clandinin, T. R. 2011; 70 (6): 1165-1177

  Abstract

  Many animals rely on visual motion detection for survival. Motion information is extracted from spatiotemporal intensity patterns on the retina, a paradigmatic neural computation. A phenomenological model, the Hassenstein-Reichardt correlator (HRC), relates visual inputs to neural activity and behavioral responses to motion, but the circuits that implement this computation remain unknown. By using cell-type specific genetic silencing, minimal motion stimuli, and in vivo calcium imaging, we examine two critical HRC inputs. These two pathways respond preferentially to light and dark moving edges. We demonstrate that these pathways perform overlapping but complementary subsets of the computations underlying the HRC. A numerical model implementing differential weighting of these operations displays the observed edge preferences. Intriguingly, these pathways are distinguished by their sensitivities to a stimulus correlation that corresponds to an illusory percept, "reverse phi," that affects many species. Thus, this computational architecture may be widely used to achieve edge selectivity in motion detection.

  View details for DOI 10.1016/j.neuron.2011.05.023

  View details for Web of Science ID 000292410700014

  View details for PubMedID 21689602

  View details for PubMedCentralID PMC3121538

• Cortical representations of olfactory input by trans-synaptic tracing NATURE Miyamichi, K., Amat, F., Moussavi, F., Wang, C., Wickersham, I., Wall, N. R., Taniguchi, H., Tasic, B., Huang, Z. J., He, Z., Callaway, E. M., Horowitz, M. A., Luo, L. 2011; 472 (7342): 191-196

  Abstract

  In the mouse, each class of olfactory receptor neurons expressing a given odorant receptor has convergent axonal projections to two specific glomeruli in the olfactory bulb, thereby creating an odour map. However, it is unclear how this map is represented in the olfactory cortex. Here we combine rabies-virus-dependent retrograde mono-trans-synaptic labelling with genetics to control the location, number and type of 'starter' cortical neurons, from which we trace their presynaptic neurons. We find that individual cortical neurons receive input from multiple mitral cells representing broadly distributed glomeruli. Different cortical areas represent the olfactory bulb input differently. For example, the cortical amygdala preferentially receives dorsal olfactory bulb input, whereas the piriform cortex samples the whole olfactory bulb without obvious bias. These differences probably reflect different functions of these cortical areas in mediating innate odour preference or associative memory. The trans-synaptic labelling method described here should be widely applicable to mapping connections throughout the mouse nervous system.

  View details for DOI 10.1038/nature09714

  View details for Web of Science ID 000289469100036

  View details for PubMedID 21179085

  View details for PubMedCentralID PMC3073090

• Latency Sensitive FMA Design 20th IEEE Symposium on Computer Arithmetic (ARITH) Galal, S., Horowitz, M. IEEE COMPUTER SOC. 2011: 129–138

  View details for DOI 10.1109/ARITH.2011.26

  View details for Web of Science ID 000296333300016

• Joint DAC/IWBDA Special Session Design and Synthesis of Biological Circuits 48th ACM/IEEE/EDAC Design Automation Conference (DAC) Densmore, D., Horowitz, M., Krishnaswamy, S., Shen, X., Arkin, A., Winfree, E., Voigt, C. ASSOC COMPUTING MACHINERY. 2011: 114–115

  View details for Web of Science ID 000297360000020

• Global Convergence Analysis of Mixed-Signal Systems 48th ACM/IEEE/EDAC Design Automation Conference (DAC) Youn, S., Kim, J., Horowitz, M. ASSOC COMPUTING MACHINERY. 2011: 498–503

  View details for Web of Science ID 000297360000093

• Global convergence analysis of mixed-signal systems Design Automation Conference (DAC) Youn, S., Kim, J., Horowitz, M. 2011: 498-503
• Energy-efficient floating point unit design Computers, IEEE Transactions on Galal, S., Horowitz, M. 2011; 99: 1-1
• Analog signal multiplexing for PSAPD-based PET detectors: simulation and experimental validation PHYSICS IN MEDICINE AND BIOLOGY Lau, F. W., Vandenbroucke, A., Reynolds, P. D., Olcott, P. D., Horowitz, M. A., Levin, C. S. 2010; 55 (23): 7149-7174

  Abstract

  A 1 mm(3) resolution clinical positron emission tomography (PET) system employing 4608 position-sensitive avalanche photodiodes (PSAPDs) is under development. This paper describes a detector multiplexing technique that simplifies the readout electronics and reduces the density of the circuit board design. The multiplexing scheme was validated using a simulation framework that models the PSAPDs and front-end multiplexing circuits to predict the signal-to-noise ratio and flood histogram performance. Two independent experimental setups measured the energy resolution, time resolution, crystal identification ability and count rate both with and without multiplexing. With multiplexing, there was no significant degradation in energy resolution, time resolution and count rate. There was a relative 6.9 ± 1.0% and 9.4 ± 1.0% degradation in the figure of merit that characterizes the crystal identification ability observed in the measured and simulated ceramic-mounted PSAPD module flood histograms, respectively.

  View details for DOI 10.1088/0031-9155/55/23/001

  View details for Web of Science ID 000284261000015

  View details for PubMedID 21081831

• Analysis of the Intact Surface Layer of Caulobacter crescentus by Cryo-Electron Tomography JOURNAL OF BACTERIOLOGY Amat, F., Comolli, L. R., Nomellini, J. F., Moussavi, F., Downing, K. H., Smit, J., Horowitz, M. 2010; 192 (22): 5855-5865

  Abstract

  The surface layers (S layers) of those bacteria and archaea that elaborate these crystalline structures have been studied for 40 years. However, most structural analysis has been based on electron microscopy of negatively stained S-layer fragments separated from cells, which can introduce staining artifacts and allow rearrangement of structures prone to self-assemble. We present a quantitative analysis of the structure and organization of the S layer on intact growing cells of the Gram-negative bacterium Caulobacter crescentus using cryo-electron tomography (CET) and statistical image processing. Instead of the expected long-range order, we observed different regions with hexagonally organized subunits exhibiting short-range order and a broad distribution of periodicities. Also, areas of stacked double layers were found, and these increased in extent when the S-layer protein (RsaA) expression level was elevated by addition of multiple rsaA copies. Finally, we combined high-resolution amino acid residue-specific Nanogold labeling and subtomogram averaging of CET volumes to improve our understanding of the correlation between the linear protein sequence and the structure at the 2-nm level of resolution that is presently available. The results support the view that the U-shaped RsaA monomer predicted from negative-stain tomography proceeds from the N terminus at one vertex, corresponding to the axis of 3-fold symmetry, to the C terminus at the opposite vertex, which forms the prominent 6-fold symmetry axis. Such information will help future efforts to analyze subunit interactions and guide selection of internal sites for display of heterologous protein segments.

  View details for DOI 10.1128/JB.00747-10

  View details for Web of Science ID 000283559300001

  View details for PubMedID 20833802

  View details for PubMedCentralID PMC2976456

• RETHINKING DIGITAL DESIGN: WHY DESIGN MUST CHANGE IEEE MICRO Shacham, O., Azizi, O., Wachs, M., Qadeer, W., Asgar, Z., Kelley, K., Stevenson, J. P., Richardson, S., Horowitz, M., Lee, B., Solomatnikov, A., Firoozshahian, A. 2010; 30 (6): 9-24

  View details for Web of Science ID 000285609700003

• Subtomogram alignment by adaptive Fourier coefficient thresholding JOURNAL OF STRUCTURAL BIOLOGY Amat, F., Comolli, L. R., Moussavi, F., Smit, J., Downing, K. H., Horowitz, M. 2010; 171 (3): 332-344

  Abstract

  In the past few years, three-dimensional (3D) subtomogram alignment has become an important tool in cryo-electron tomography (CET). This technique allows one to produce higher resolution images of structures which can not be reconstructed using single-particle methods. Building on previous work, we present a new dissimilarity measure between subtomograms that works well for the noisy images that often occur in CET images. A technique that is more robust to noise provides the ability to analyze macromolecules in thicker samples such as whole cells or lower the defocus in thinner samples to push the first zero of the Contrast Transfer Function (CTF). Our method, Threshold Constrained Cross-Correlation (TCCC), uses statistics of the noise to automatically select only a small percentage of the Fourier coefficients to compute the cross-correlation, which has two main advantages: first, it reduces the influence of the noise by looking at only those peaks dominated by signal; and second, it avoids the missing wedge normalization problem since we consider the same number of coefficients for all possible pairs of subtomograms. We present results with synthetic and real data to compare our approach with other existing methods under different SNR and missing wedge conditions, and show that TCCC improves alignment results for datasets with SNR<0.1. We have made our source code freely available for the community.

  View details for DOI 10.1016/j.jsb.2010.05.013

  View details for Web of Science ID 000280680100010

  View details for PubMedID 20621702

• The Frankencamera: An Experimental Platform for Computational Photography ACM TRANSACTIONS ON GRAPHICS Adams, A., Jacobs, D. E., Dolson, J., Tico, M., Pulli, K., Talvala, E., Ajdin, B., Vaquero, D., Lensch, H. P., Horowitz, M., Park, S. H., Gelfand, N., Baek, J., Matusik, W., Levoy, M. 2010; 29 (4)

  View details for DOI 10.1145/1778765.1778766

  View details for Web of Science ID 000279806600001

• Fast, Non-Monte-Carlo Estimation of Transient Performance Variation Due to Device Mismatch IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS Kim, J., Jones, K. D., Horowitz, M. A. 2010; 57 (7): 1746-1755

  View details for DOI 10.1109/TCSI.2009.2035418

  View details for Web of Science ID 000282562000030

• 3D segmentation of cell boundaries from whole cell cryogenic electron tomography volumes JOURNAL OF STRUCTURAL BIOLOGY Moussavi, F., Heitz, G., Amat, F., Comolli, L. R., Koller, D., Horowitz, M. 2010; 170 (1): 134-145

  Abstract

  Cryogenic electron tomography (cryo-ET) has gained increasing interest in recent years due to its ability to image whole cells and subcellular structures in 3D at nanometer resolution in their native environment. However, due to dose restrictions and the inability to acquire high tilt angle images, the reconstructed volumes are noisy and have missing information. Thus, features are unreliable, and precision extraction of the cell boundary is difficult, manual and time intensive. This paper presents an efficient recursive algorithm called BLASTED (Boundary Localization using Adaptive Shape and Texture Discovery) to automatically extract the cell boundary using a conditional random field (CRF) framework in which boundary points and shape are jointly inferred. The algorithm learns the texture of the boundary region progressively, and uses a global shape model and shape-dependent features to propose candidate boundary points on a slice of the membrane. It then updates the shape of that slice by accepting the appropriate candidate points using local spatial clustering, the global shape model, and trained boosted texture classifiers. The BLASTED algorithm segmented the cell membrane over an average of 93% of the length of the cell in 19 difficult cryo-ET datasets.

  View details for DOI 10.1016/j.jsb.2009.12.015

  View details for Web of Science ID 000276329600016

  View details for PubMedID 20035877

• Static control logic for microfluidic devices using pressure-gain valves NATURE PHYSICS Weaver, J. A., Melin, J., Stark, D., Quake, S. R., Horowitz, M. A. 2010; 6 (3): 218-223

  View details for DOI 10.1038/NPHYS1513

  View details for Web of Science ID 000275024000024

• Timing Robustness in the Budding and Fission Yeast Cell Cycles PLOS ONE Mangla, K., Dill, D. L., Horowitz, M. A. 2010; 5 (2)

  Abstract

  Robustness of biological models has emerged as an important principle in systems biology. Many past analyses of Boolean models update all pending changes in signals simultaneously (i.e., synchronously), making it impossible to consider robustness to variations in timing that result from noise and different environmental conditions. We checked previously published mathematical models of the cell cycles of budding and fission yeast for robustness to timing variations by constructing Boolean models and analyzing them using model-checking software for the property of speed independence. Surprisingly, the models are nearly, but not totally, speed-independent. In some cases, examination of timing problems discovered in the analysis exposes apparent inaccuracies in the model. Biologically justified revisions to the model eliminate the timing problems. Furthermore, in silico random mutations in the regulatory interactions of a speed-independent Boolean model are shown to be unlikely to preserve speed independence, even in models that are otherwise functional, providing evidence for selection pressure to maintain timing robustness. Multiple cell cycle models exhibit strong robustness to timing variation, apparently due to evolutionary pressure. Thus, timing robustness can be a basis for generating testable hypotheses and can focus attention on aspects of a model that may need refinement.

  View details for DOI 10.1371/journal.pone.0008906

  View details for Web of Science ID 000274209700002

  View details for PubMedID 20126540

  View details for PubMedCentralID PMC2813865

• Energy-Performance Tradeoffs in Processor Architecture and Circuit Design: A Marginal Cost Analysis 37th International Symposium on Computer Architecture Azizi, O., Mahesri, A., Lee, B. C., Patel, S. J., Horowitz, M. ASSOC COMPUTING MACHINERY. 2010: 26–36

  View details for Web of Science ID 000287049300004

• Chapter Thirteen-Alignment of Cryo-Electron Tomography Datasets Methods in enzymology Amat, F., Castaño-Diez, D., Lawrence, A., Moussavi, F., Winkler, H., Horowitz, M. Elsevier. 2010: 343–367
• 2010 Timing Robustness in the Budding and Fission Yeast Cell Cycles.  PLoS ONE K, M., DL, D., A, H. M. 2010; 2 (5): e8906

  View details for DOI 10.1371/journal.pone.0008906

• An integrated framework for joint design space exploration of microarchitecture and circuits Azizi, O., Mahesri, A., Stevenson, J., P., Patel, S., J., Horowitz, M. 2010
• An efficient test vector generation for checking analog/mixed-signal functional models Lim, B., C., Kim, J., Horowitz, M., A. 2010

  View details for DOI 10.1145/1837274.1837468

• Intent-leveraged optimization of analog circuits via homotopy Jeeradit, M., Kim, J., Horowitz, M. 2010
• Fortifying analog models with equivalence checking and coverage analysis Horowitz, M., Jeeradit, M., Lau, F., Liao, S., Lim, B., Mao, J. 2010

  View details for DOI 10.1145/1837274.1837381

• ALIGNMENT OF CRYO-ELECTRON TOMOGRAPHY DATASETS METHODS IN ENZYMOLOGY, VOL 482: CRYO-EM, PART B: 3-D RECONSTRUCTION Amat, F., Castano-Diez, D., Lawrence, A., Moussavi, F., Winkler, H., Horowitz, M. 2010; 482: 343-367

  Abstract

  Data acquisition of cryo-electron tomography (CET) samples described in previous chapters involves relatively imprecise mechanical motions: the tilt series has shifts, rotations, and several other distortions between projections. Alignment is the procedure of correcting for these effects in each image and requires the estimation of a projection model that describes how points from the sample in three-dimensions are projected to generate two-dimensional images. This estimation is enabled by finding corresponding common features between images. This chapter reviews several software packages that perform alignment and reconstruction tasks completely automatically (or with minimal user intervention) in two main scenarios: using gold fiducial markers as high contrast features or using relevant biological structures present in the image (marker-free). In particular, we emphasize the key decision points in the process that users should focus on in order to obtain high-resolution reconstructions.

  View details for DOI 10.1016/S0076-6879(10)82014-2

  View details for Web of Science ID 000283462200013

  View details for PubMedID 20888968

• Understanding Sources of Inefficiency in General-Purpose Chips 37th International Symposium on Computer Architecture Hameed, R., Qadeer, W., Wachs, M., Azizi, O., Solomatnikov, A., Lee, B. C., Richardson, S., Kozyrakis, C., Horowitz, M. ASSOC COMPUTING MACHINERY. 2010: 37–47

  View details for Web of Science ID 000287049300005

• Energy-Performance Tunable Logic IEEE JOURNAL OF SOLID-STATE CIRCUITS Nezamfar, B., Alon, E., Horowitz, M. 2009; 44 (9): 2554-2567

  View details for DOI 10.1109/JSSC.2009.2025344

  View details for Web of Science ID 000269390700027

• On-Die Power Supply Noise Measurement Techniques IEEE TRANSACTIONS ON ADVANCED PACKAGING Alon, E., Abramzon, V., Nezamfar, B., Horowitz, M. 2009; 32 (2): 248-259

  View details for DOI 10.1109/TADVP.2009.2012521

  View details for Web of Science ID 000266778000003

• 1 mm(3) Resolution Breast-Dedicated PET System IEEE Nuclear Science Symposium/Medical Imaging Conference Lau, F. W., Fang, C., Reynolds, P. D., Olcott, P. D., Vandenbroucke, A., Spanoudaki, V. C., Olutade, F., Horowitz, M. A., Levin, C. S. IEEE. 2009: 5378–5381

  View details for Web of Science ID 000268656002327

• Using a configurable processor generator for computer architecture prototyping Solomatnikov, A., Firoozshahian, A., Shacham, O., Asgar, Z., Wachs, M., Qadeer, W., Horowitz, M. A. 2009

  View details for DOI 10.1145/1669112.1669159

• Area-efficiency in CMP core design: co-optimization of microarchitecture and physical design SIGARCH Comput. Archit. New Azizi, O., Mahesri, A., Patel, S., J., Horowitz, M. 2009; 37 (2): 56-65

  View details for DOI 10.1145/1577129.1577138

• Energy-Performance Tunable Logic IEEE Custom Integrated Circuits Conference Nezamfar, B., Horowitz, M. IEEE. 2009: 183–186

  View details for Web of Science ID 000275926300039

• A Memory System Design Framework: Creating Smart Memories 36th Annual International Symposium on Computer Architecture Firoozshahian, A., Solomatnikov, A., Shacham, O., Asgar, Z., Richardson, S., Kozyrakis, C., Horowitz, M. ASSOC COMPUTING MACHINERY. 2009: 406–417

  View details for Web of Science ID 000268225000037

• Front-End Electronics for a 1 mm(3) Resolution Avalanche Photodiode-Based PET System with Analog Signal Multiplexing IEEE Nuclear Science Symposium/Medical Imaging Conference Lau, F. W., Vandenbroucke, A., Reynolds, P. D., Olcott, P. D., Horowitz, M. A., Levin, C. S. IEEE. 2009: 3146–3149

  View details for Web of Science ID 000268656001256

• IN FIELD, ENERGY-PERFORMANCE TUNABLE FPGA ARCHITECTURES 19th International Conference on Field Programmable Logic and Applications Nezamfar, B., Horowitz, M. IEEE. 2009: 262–267

  View details for Web of Science ID 000277506300040

• Stochastic Steady-State and AC Analyses of Mixed-Signal Systems 46th ACM/IEEE Design Automation Conference (DAC 2009) Kim, J., Ren, J., Horowitz, M. A. IEEE. 2009: 376–381

  View details for Web of Science ID 000279394200077

• Leveraging Designer's Intent: A Path Toward Simpler Analog CAD Tools IEEE Custom Integrated Circuits Conference Kim, J., Jeeradit, M., Lim, B., Horowitz, M. A. IEEE. 2009: 613–620

  View details for Web of Science ID 000275926300133

• Comparative Evaluation of Memory Models for Chip Multiprocessors ACM TRANSACTIONS ON ARCHITECTURE AND CODE OPTIMIZATION Leverich, J., Arakida, H., Solomatnikov, A., Firoozshahian, A., Horowitz, M., Kozyrakis, C. 2008; 5 (3)

  View details for DOI 10.1145/1455650.1455651

  View details for Web of Science ID 000261844300001

• Architecture and inherent robustness of a bacterial cell-cycle control system PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Shen, X., Collier, J., Dill, D., Shapiro, L., Horowitz, M., McAdams, H. H. 2008; 105 (32): 11340-11345

  Abstract

  A closed-loop control system drives progression of the coupled stalked and swarmer cell cycles of the bacterium Caulobacter crescentus in a near-mechanical step-like fashion. The cell-cycle control has a cyclical genetic circuit composed of four regulatory proteins with tight coupling to processive chromosome replication and cell division subsystems. We report a hybrid simulation of the coupled cell-cycle control system, including asymmetric cell division and responses to external starvation signals, that replicates mRNA and protein concentration patterns and is consistent with observed mutant phenotypes. An asynchronous sequential digital circuit model equivalent to the validated simulation model was created. Formal model-checking analysis of the digital circuit showed that the cell-cycle control is robust to intrinsic stochastic variations in reaction rates and nutrient supply, and that it reliably stops and restarts to accommodate nutrient starvation. Model checking also showed that mechanisms involving methylation-state changes in regulatory promoter regions during DNA replication increase the robustness of the cell-cycle control. The hybrid cell-cycle simulation implementation is inherently extensible and provides a promising approach for development of whole-cell behavioral models that can replicate the observed functionality of the cell and its responses to changing environmental conditions.

  View details for DOI 10.1073/pnas.0805258105

  View details for Web of Science ID 000258560700056

  View details for PubMedID 18685108

  View details for PubMedCentralID PMC2516238

• Integrated regulation for energy-efficient digital circuits IEEE Custom Integrated Circuits Conference Alon, E., Horowitz, M. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2008: 1795–1807

  View details for DOI 10.1109/JSSC.2008.925403

  View details for Web of Science ID 000257950800009

• A 90 nm CMOS 16 Gb/s transceiver for optical interconnects IEEE Radio Frequency Integrated Circuits Symposium (RFIC) Palermo, S., Emami-Neyestanak, A., Horowitz, M. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2008: 1235–46

  View details for DOI 10.1109/JSSC.2008.920330

  View details for Web of Science ID 000255354300019

• Digital circuit design trends 20th Symposium on VLSI Circuits Horowitz, M., Stark, D., Alon, E. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2008: 757–61

  View details for DOI 10.1109/JSSC.2008.917523

  View details for Web of Science ID 000254560300002

• A 24 Gb/s software programmable analog multi-tone transmitter 20th Symposium on VLSI Circuits Amirkhany, A., Abbasfar, A., Savoj, J., Jeeradit, M., Garlepp, B., Kollipara, R. T., Stojanovic, V., Horowitz, M. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2008: 999–1009

  View details for DOI 10.1109/JSSC.2008.917520

  View details for Web of Science ID 000254560300029

• Markov random field based automatic image alignment for electron tomography 4th International Conference on Electron Tomography Amat, F., Moussavi, F., Comolli, L. R., Elidan, G., Downing, K. H., Horowitz, M. ACADEMIC PRESS INC ELSEVIER SCIENCE. 2008: 260–75

  Abstract

  We present a method for automatic full-precision alignment of the images in a tomographic tilt series. Full-precision automatic alignment of cryo electron microscopy images has remained a difficult challenge to date, due to the limited electron dose and low image contrast. These facts lead to poor signal to noise ratio (SNR) in the images, which causes automatic feature trackers to generate errors, even with high contrast gold particles as fiducial features. To enable fully automatic alignment for full-precision reconstructions, we frame the problem probabilistically as finding the most likely particle tracks given a set of noisy images, using contextual information to make the solution more robust to the noise in each image. To solve this maximum likelihood problem, we use Markov Random Fields (MRF) to establish the correspondence of features in alignment and robust optimization for projection model estimation. The resulting algorithm, called Robust Alignment and Projection Estimation for Tomographic Reconstruction, or RAPTOR, has not needed any manual intervention for the difficult datasets we have tried, and has provided sub-pixel alignment that is as good as the manual approach by an expert user. We are able to automatically map complete and partial marker trajectories and thus obtain highly accurate image alignment. Our method has been applied to challenging cryo electron tomographic datasets with low SNR from intact bacterial cells, as well as several plastic section and X-ray datasets.

  View details for DOI 10.1016/j.jsb.2007.07.007

  View details for Web of Science ID 000254349100006

  View details for PubMedID 17855124

• Verification of Chip Multiprocessor Memory Systems Using A Relaxed Scoreboard 41st Annual IEEE/ACM International Symposium on Microarchitecture Shacham, O., Wachs, M., Solomatnikov, A., Firoozshahian, A., Richardson, S., Horowitz, M. IEEE COMPUTER SOC. 2008: 294–305

  View details for Web of Science ID 000264849800026

• Circuit-Level Requirements for MOSFET-Replacement Devices IEEE International Electron Devices Meeting Kam, H., King-Liu, T., Alon, E., Horowitz, M. IEEE. 2008: 427–427

  View details for Web of Science ID 000265829300100

• The case for simple, visible cache coherency Kunz, R., Horowitz, M. 2008

  View details for DOI 10.1145/1353522.1353532

• Circuit-level requirements for MOSFET-replacement devices Electron Devices Meeting, 2008. IEDM 2008. IEEE International Kam, H., King-Liu, T., Alon, E., Horowitz, M. 2008: 1-1
• Markov random field based automatic image alignment for electron tomography Journal of Structural Biology Amat, F., Moussavi, F., Comolli, L., R., Elidan, G., Downing et al, K., H. 2008; 161 (3): 260-75
• A High-speed, Low-power 3D-SRAM Architecture IEEE Custom Integrated Circuits Conference Nho, H. H., Horowitz, M., Wong, S. S. IEEE. 2008: 201–204

  View details for Web of Science ID 000262643900045

• Processor performance modeling using symbolic simulation IEEE International Symposium on Performance Analysis of Systems and Software Azizi, O., Collins, J., Patil, D., Wang, H., Horowitz, M. IEEE COMPUTER SOC. 2008: 127–138

  View details for Web of Science ID 000255984000013

• A 14-mW 6.25-Gb/s transceiver in 90-nm CMOS IEEE International Solid-State Circuits Conference (ISSCC) Poulton, J., Palmer, R., Fuller, A. M., Greer, T., Eyles, J., Dally, W. J., Horowitz, M. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2007: 2745–57

  View details for DOI 10.1109/JSSC.2007.908692

  View details for Web of Science ID 000251292000012

• An optical interconnect transceiver at 1550 nm using low-voltage electroabsorption modulators directly integrated to CMOS JOURNAL OF LIGHTWAVE TECHNOLOGY Roth, J. E., Palermo, S., Helman, N. C., Bour, D. P., Miller, D. A., Horowitz, M. 2007; 25 (12): 3739-3747

  View details for DOI 10.1109/JLT.2007.909334

  View details for Web of Science ID 000251943600011

• A heuristic for optimizing stochastic activity networks with applications to statistical digital circuit sizing OPTIMIZATION AND ENGINEERING Kim, S., Boyd, S. P., Yun, S., Patil, D. D., Horowitz, M. A. 2007; 8 (4): 397-430

  View details for DOI 10.1007/s11081-007-9011-5

  View details for Web of Science ID 000249952000003

• Veiling glare in high dynamic range imaging ACM SIGGRAPH 2007 Conference Talvala, E., Adams, A., Horowitz, M., Levoy, M. ASSOC COMPUTING MACHINERY. 2007

  View details for DOI 10.1145/1239451.1239488

  View details for Web of Science ID 000248914000040

• Power optimization for SRAM and its scaling IEEE TRANSACTIONS ON ELECTRON DEVICES Morifuji, E., Patil, D., Horowitz, M., Nishi, Y. 2007; 54 (4): 715-722

  View details for DOI 10.1109/TED.2007.891869

  View details for Web of Science ID 000245327900014

• Chip multi-processor generator 44th ACM/IEEE Design Automation Conference Solomatnikov, A., Firoozshahian, A., Qadeer, W., Shacham, O., Kelley, K., Asgar, Z., Wachs, M., Hameed, R., Horowitz, M. IEEE. 2007: 262–263

  View details for Web of Science ID 000249725800052

• Variable domain transformation for linear PAC analysis of mixed-signal systems IEEE/ACM International Conference on Computer-Aided Design Kim, J., Jones, K. D., Horowitz, M. A. IEEE. 2007: 887–894

  View details for Web of Science ID 000253303700142

• Fast, non-monte-carlo estimation of transient performance variation due to device mismatch 44th ACM/IEEE Design Automation Conference Kim, J., Jones, K. D., Horowitz, M. A. IEEE. 2007: 440–443

  View details for Web of Science ID 000249725800092

• Integrated regulation for energy-efficient digital circuits IEEE Custom Integrated Circuits Conference Alon, E., Horowitz, M. IEEE. 2007: 389–392

  View details for Web of Science ID 000252233200090

• Variable domain transformation for linear PAC analysis of mixed-signal systems Kim, J., Jones, K., D., Horowitz, M., A. 2007
• Fast, Non-Monte-Carlo Estimation of Transient Performance Variation Due to Device Mismatch Kim, J., Jones, K., D., Horowitz, M., A. 2007
• 1550nm Optical Interconnect Transceiver with Low Voltage Electroabsorption Modulators Flip-Chip Bonded to 90nm CMOS Roth, J., E., Palermo, S., Helman, N., C., Bour, D., P., Miller, D., A. B., Horowitz, M. 2007
• Chip Multi-Processor Generator. DAC Solomatnikov, A., Firoozshahian, A., Qadeer, W., Shacham, O., Kelley, K., Asgar, Z., Horowitz, M. A. 2007
• Integrated Regulation for Energy-Efficient Digital Circuits Alon, E., Horowitz, M. 2007
• A 24Gbps Software Programmable Multi-Channel Transmitter Amirkhany, A., Abbasfar, A., Savoj, J., Jeeradit, M., Garlepp, B., Stojanovic, V., Horowitz, M. A. 2007
• A 12GS/S Phase-Calibrated CMOS Digital-to-Analog Coverter Savoj, J., Abbasfar, A., Amirkhany, A., Garlepp, B., Jeeradit, M. 2007
• A 14mW 6.25Gb/s Transceiver in 90nm CMOS for Serial Chip-to-Chip Communications Palmer, R., Poulton, J., Dally, W., J., Eyles, J., Fuller, A., M., Greer, T., Horowitz, M. A. 2007
• Synthetic aperture focusing using dense camera arrays Workshop on Advanced 3D Imaging for Safety and Security held in Conjunction with the International Conference on Computer Vision and Pattern Recognition Vaish, V., Garg, G., Talvala, E., Antunez, E., Wilburn, B., Horowitz, M., Levoy, M. SPRINGER. 2007: 159-?

  View details for Web of Science ID 000250475200007

• A new technique for characterization of digital-to-analog converters in high-speed systems Design, Automation and Test in Europe Conference and Exhibition (DATE 07) Savoj, J., Abbasfar, A., Amirkhany, A., Garlepp, B. W., Horowitz, M. A. IEEE. 2007: 433–438

  View details for Web of Science ID 000252175700073

• A 24Gb/s software programmable multi-channel transmitter 20th Symposium on VLSI Circuits Amirkhany, A., Abbasfar, A., Savoj, J., Jeeradit, M., Garlepp, B., Stoianovic, V., Horowitz, M. JAPAN SOCIETY APPLIED PHYSICS. 2007: 38–39

  View details for Web of Science ID 000250541000014

• Comparing Memory Systems for Chip Multiprocessors 34th Annual International Symposium on Computer Architecture Leverich, J., Arakida, H., Solomatnikov, A., Firoozshahian, A., Horowitz, M., Kozyrakis, C. ASSOC COMPUTING MACHINERY. 2007: 358–368

  View details for Web of Science ID 000265786200032

• Noise analysis of LSO-PSAPD PET detector front-end multiplexing circuits IEEE Nuclear Science Symposium/Medical Imaging Conference Lau, F. W., Olcott, P. D., Horowitz, M. A., Peng, H., Levin, C. S. IEEE. 2007: 3212–3219

  View details for Web of Science ID 000257380402138

• Practical limits of multi-tone signaling over high-speed backplane electrical links IEEE International Conference on Communications (ICC 2007) Amirkhany, A., Abbasfar, A., Stojanovic, V., Horowitz, M. A. IEEE. 2007: 2693–2698

  View details for Web of Science ID 000257882501208

• Time-variant characterization and compensation of wideband circuits IEEE Custom Integrated Circuits Conference Amirkhany, A., Abbasfar, A., Savoj, J., Horowitz, M. A. IEEE. 2007: 487–490

  View details for Web of Science ID 000252233200109

• Robust energy-efficient adder topologies 18th IEEE Symposium on Computer Arithmetic Patil, D., Azizi, O., Horowitz, M., Ho, R., Ananthraman, R. IEEE COMPUTER SOC. 2007: 16–25

  View details for Web of Science ID 000248520400003

• Measurement of supply pin current distributions in integrated circuit packages 16th IEEE Topical Meeting on Electrical Performance of Electronic Packaging Weaver, J. A., Horowitz, M. A. IEEE. 2007: 7–10

  View details for Web of Science ID 000251017800002

• Light field microscopy ACM TRANSACTIONS ON GRAPHICS Levoy, M., Ng, R., Adams, A., Footer, M., Horowitz, M. 2006; 25 (3): 924-934

  View details for Web of Science ID 000239817400054

• Replica compensated linear regulators for supply-regulated phase-locked loops IEEE JOURNAL OF SOLID-STATE CIRCUITS Alon, E., Kim, J., Pamarti, S., Chang, K., Horowitz, M. 2006; 41 (2): 413-424

  View details for DOI 10.1109/JSSC.2005.862347

  View details for Web of Science ID 000235372800011

• Analog Multi-Tone Signaling for High-Speed Backplane Electrical Links IEEE Global Telecommunications Conference (GLOBECOM 06) Amirkhany, A., Abbasfar, A., Stojanovic, V., Horowitz, M. A. IEEE. 2006

  View details for Web of Science ID 000288765602170

• High-speed transmitters in 90nm CMOS for high-density optical interconnects 32nd European Solid-State Circuits Conference Palermo, S., Horowitz, M. IEEE. 2006: 508–511

  View details for Web of Science ID 000245212800122

• The implementation of a 2-core, multi-threaded Itanium family processor IEEE International Solid-State Circuits Conference (ISSCC 2005) Naffziger, S., Stackhouse, B., Grutkowski, T., Josephson, D., Desai, J., Alon, E., Horowitz, M. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2006: 197–209

  View details for DOI 10.1109/JSSC.2005.859894

  View details for Web of Science ID 000234305600022

• Measurement of via currents in printed circuit boards using inductive loops 15th IEEE Topical Meeting on Electrical Performance of Electronic Packaging Weaver, J. A., Horowitz, M. A. IEEE. 2006: 37–40

  View details for Web of Science ID 000243330600009

• A heuristic method for statistical digital circuit sizing 4th Conference on Design and Process Integration for Microelectronic Manufacturing Boyd, S., Kim, S., Patil, D., Horowitz, M. SPIE-INT SOC OPTICAL ENGINEERING. 2006

  View details for DOI 10.1117/12.657499

  View details for Web of Science ID 000238444200008

• Compensation for multimode fiber dispersion by adaptive optics OPTICS LETTERS Shen, X. L., Kahn, J. M., Horowitz, M. A. 2005; 30 (22): 2985-2987

  Abstract

  Adaptive optics is used to compensate for modal dispersion in digital transmission through multimode fiber (MMF). At the transmitter, a spatial light modulator (SLM) controls the launched field pattern. An estimate of intersymbol interference (ISI) caused by modal dispersion is formed at the receiver and fed back to the transmitter, where the SLM is adjusted to minimize ISI. Error-free transmission of 10 Gbit/s non-return-to-zero signals through standard 50 microm graded-index MMFs up to 11.1 km long is demonstrated. It is shown that a single SLM can compensate for modal dispersion across a 600 GHz bandwidth.

  View details for Web of Science ID 000233258800005

  View details for PubMedID 16315696

• Digital circuit optimization via geometric programming OPERATIONS RESEARCH Boyd, S. P., Kim, S. J., Patil, D. D., Horowitz, M. A. 2005; 53 (6): 899-932

  View details for DOI 10.1287/opre.1050.0254

  View details for Web of Science ID 000234756000002

• False coupling exploration in timing analysis IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS Tseng, K., Horowitz, M. 2005; 24 (11): 1795-1805

  View details for DOI 10.1109/TCAD.2005.852435

  View details for Web of Science ID 000232971600012

• Dual photography ACM SIGGRAPH 2005 Conference Sen, P., Chen, B., Garg, G., Marschner, S. R., Horowitz, M., Levoy, M., Lensch, H. P. ASSOC COMPUTING MACHINERY. 2005: 745–55

  View details for Web of Science ID 000231223700045

• High performance imaging using large camera arrays ACM SIGGRAPH 2005 Conference Wilburn, B., Joshi, N., Vaish, V., Talvala, E. V., Antunez, E., Barth, A., Adams, A., Horowitz, M., Levoy, M. ASSOC COMPUTING MACHINERY. 2005: 765–76

  View details for Web of Science ID 000231223700047

• On task mapping optimization for parallel decoding of low-density parity-check codes on message-passing architectures PARALLEL COMPUTING Al-Rawi, G., Cioffi, J., Horowitz, M. 2005; 31 (5): 462-490

  View details for DOI 10.1016/j.parco.2004.12.009

  View details for Web of Science ID 000230195500003

• A 20-Gb/s 0.13-mu m CMOS serial link transmitter using an LC-PLL to directly drive the output multiplexer Symposium on VLSI Circuits Chiang, P., Dally, W. J., Lee, M. J., Senthinathan, R., Oh, Y., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2005: 1004–11

  View details for DOI 10.1109/JSSC.2004.842841

  View details for Web of Science ID 000228564400025

• Autonomous dual-mode (PAM2/4) serial link transceiver with adaptive equalization and data recovery Symposium on VLSI Circuits Stojanovic, V., Ho, A., Garlepp, B. W., Chen, F., Wei, J., Tsang, G., Alon, E., Kollipara, R. T., Werner, C. W., Zerbe, J. L., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2005: 1012–26

  View details for DOI 10.1109/JSSC.2004.842863

  View details for Web of Science ID 000228564400026

• Circuits and techniques for high-resolution measurement of on-chip power supply noise Symposium on VLSI Circuits Alon, E., Stojanovic, V., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2005: 820–28

  View details for DOI 10.1109/JSSC.2004.842853

  View details for Web of Science ID 000228564400003

• Architecture and circuit techniques for a 1.1-GHz 16-kb reconfigurable memory in 0.18-mu m CMOS IEEE International Solid-State Circuits Conference Mai, K., Ho, R., Alon, E., Liu, D., Kim, Y., Patil, D., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2005: 261–75

  View details for Web of Science ID 000226124500027

• Clocking and circuit design for a parallel I/O on a first-generation CELL processor Chang, K., Pamarti, S., Kaviani, K., Alon, E., Xudong, S., Chin, T., J., Horowitz, M. A. 2005
• A new method for design of robust digital circuits. Patil, D., Yun, S., Kim, S., J, Cheung, A., Horowitz, M., Boyd, S. 2005
• Opportunities for optics in integrated circuits applications. Solid-State Circuits Conference Miller, D., A. B., Bhatnagar, A., Palermo, S., Emami-Neyestanak, A., Horowitz, M., A. 2005
• High-speed videography using a dense camera array 26th International Congress on High-Speed Photography and Photonics Wilburn, B., Joshi, N., Vaish, V., Levoy, M., Horowitz, M. SPIE-INT SOC OPTICAL ENGINEERING. 2005: 913–920

  View details for Web of Science ID 000228994200101

• A new method for design of robust digital circuits 6th International Symposium on Quality Electronic Design Patil, D., Yun, S. H., Kim, S. J., Cheung, A., Horowitz, M., Boyd, S. IEEE COMPUTER SOC. 2005: 676–681

  View details for Web of Science ID 000228486600110

• Scaling, power, and the future of CMOS IEEE International Electron Devices Meeting Horowitz, M., Alon, E., Patil, D., Naffziger, S., Kumar, R., Bernstein, K. IEEE. 2005: 11–17

  View details for Web of Science ID 000236225100002

• Scalable circuits for supply noise measurement 31st European Solid-State Circuits Conference Abramzon, V., Alon, E., Nezamfar, B., Horowitz, M. IEEE. 2005: 463–466

  View details for Web of Science ID 000235469600109

• Synthetic aperture confocal imaging Annual Symposium of the ACM SIGGRAPH Levoy, M., Chen, B., Vaish, V., Horowitz, M., McDowall, I., Bolas, M. ASSOC COMPUTING MACHINERY. 2004: 825–34

  View details for Web of Science ID 000222972600083

• Methods for true energy-performance optimization IEEE JOURNAL OF SOLID-STATE CIRCUITS Markovic, D., Stojanovic, V., Nikolic, B., Horowitz, M. A., Brodersen, R. W. 2004; 39 (8): 1282-1293

  View details for DOI 10.1109/JSSC.2004.831796

  View details for Web of Science ID 000222902600007

• The stream virtual machine 13th International Conference on Parallel Architecture and Compilation Techniques Labonte, F., Mattson, P., Thies, W., Buck, I., Kozyrakis, C., Horowitz, M. IEEE COMPUTER SOC. 2004: 267–277

  View details for Web of Science ID 000224469900025

• Adaptive equalization and data recovery in a dual-mode (PAM2/4) serial link transceiver Symposium on VLSI Circuits Stojanovic, V., Ho, A., Garlepp, B., Chen, F., Wei, J., Alon, E., Werner, C., Zerbe, J., Horowitz, M. A. IEEE. 2004: 348–351

  View details for Web of Science ID 000224752900085

• Common-mode backchannel signaling system for differential high-speed links Symposium on VLSI Circuits Ho, A., Stojanovic, V., Chen, F., Werner, C., Tsang, G., Alon, E., Kollipara, R., Zerbe, J., Horowitz, M. A. IEEE. 2004: 352–355

  View details for Web of Science ID 000224752900086

• Burst mode packet receiver using a second order DLL Symposium on VLSI Circuits LEE, H., YUE, C. H., Palermo, S., Mai, K. W., Horowitz, M. IEEE. 2004: 264–267

  View details for Web of Science ID 000224752900064

• Circuits and techniques for high-resolution measurement of on-chip power supply noise Alon, E., Stojanovic, V., Horowitz, M. 2004
• Adaptive equalization and data recovery in a dual-mode (PAM2/4) serial link transceiver Stojanovic, V., Ho, A., Garlepp, B., Chen, F., Wei, J., Alon, E., Horowitz, M. A. 2004
• Equalization of modal dispersion in multimode fiber using spatial light modulators IEEE Global Telecommunications Conference (GLOBECOM 04) Alon, E., Stojanovic, V., Kahn, J. M., Boyd, S., Horowitz, M. IEEE. 2004: 1023–1029

  View details for Web of Science ID 000226689900195

• 20Gb/s 0.13 mu m CMOS serial link transmitter using an LC-PLL to directly drive the output multiplexer Chiang, P., Dally, W., J., Lee, M., J. E., Senthinathan, R., Yangjin, O., Horowitz, M. 2004
• Burst mode packet receiver using a second order DLL Lee, H., C., Yue, C., H., Palermo, S., Mai, K., W., Horowitz, M. 2004
• Common-mode backchannel signaling system for differential high-speed links Ho, A., Stojanovic, V., Chen, F., Werner, C., Tsang, G., Alon, E., Horowitz, M. A. 2004
• Optimal linear precoding with theoretical and practical data rates in high-speed serial-link backplane communication IEEE International Conference on Communications (ICC 2004) Stojanovic, V., Amirkhany, A., Horowitz, M. A. IEEE. 2004: 2799–2806

  View details for Web of Science ID 000223459600546

• Multi-tone signaling for high-speed backplane electrical links IEEE Global Telecommunications Conference (GLOBECOM 04) Amirkhany, A., Stojanovic, V., Horowitz, M. A. IEEE. 2004: 1111–1117

  View details for Web of Science ID 000226689900212

• CMOS transceiver with baud rate clock recovery for optical interconnects Symposium on VLSI Circuits Emami-Neyestanak, A., Palermo, S., Lee, H. C., Horowitz, M. IEEE. 2004: 410–413

  View details for Web of Science ID 000224752900101

• High-speed videography using a dense camera array Conference on Computer Vision and Pattern Recognition Wilburn, B., Joshi, N., Vaish, V., Levoy, M., Horowitz, M. IEEE COMPUTER SOC. 2004: 294–301

  View details for Web of Science ID 000223605500039

• Architecture and circuit techniques for a reconfigurable memory block IEEE International Solid-State Circuits Conference Mai, K., Ho, R., Alon, E., Liu, D., Kim, Y., Patil, D., Horowitz, M. IEEE. 2004: 500–501

  View details for Web of Science ID 000221633800210

• How scaling will change processor architecture IEEE International Solid-State Circuits Conference Horowitz, M., Daily, W. IEEE. 2004: 132–133

  View details for Web of Science ID 000221633800047

• Equalization and clock recovery for a 2.5-10-Gb/s 2-PAM/4-PAM backplane transceiver cell IEEE International Solid-State Circuits Conference Zerbe, J. L., Werner, C. W., Stojanovic, V., Chen, F., Wei, J., Tsang, G., Kim, D., Stonecypher, W. F., Ho, A., Thrush, T. P., Kollipara, R. T., Horowitz, M. A., Donnelly, K. S. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2003: 2121–30

  View details for DOI 10.1109/JSSC.2003.818572

  View details for Web of Science ID 000187569900013

• A 10-GHz global clock distribution using coupled standing-wave oscillators IEEE International Solid-State Circuits Conference O'Mahony, F., Yue, C. P., Horowitz, M. A., Wong, S. S. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2003: 1813–20

  View details for DOI 10.1109/JSSC.2003.818299

  View details for Web of Science ID 000186249100004

• Design of CMOS adaptive-bandwidth PLL/DLLs: A general approach IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS II-EXPRESS BRIEFS Kim, J., Horowitz, M. A., Wei, G. Y. 2003; 50 (11): 860-869

  View details for DOI 10.1109/TCSII.2003.819120

  View details for Web of Science ID 000186646500010

• Scaling Internet routers using optics SIGCOMM 2003 Conference Keslassy, I., Chuang, S. T., Yu, K., Miller, D., Horowitz, M., Solgaard, O., McKeown, N. ASSOC COMPUTING MACHINERY. 2003: 189–200

  View details for Web of Science ID 000188215800017

• Efficient on-chip global interconnects Symposium on VLSI Circuits Ho, R., Mai, K., Horowitz, M. JAPAN SOCIETY APPLIED PHYSICS. 2003: 271–274

  View details for Web of Science ID 000185582200075

• Implementing an untrusted operating system on trusted hardware. Operating Systems Review Lie, D., Thekkath, C. A., Horowitz, M. 2003; 37 (5): 178-92
• A framework for designing reusable analog circuits Liu, D., Sidiropoulos, S., Horowitz, M. 2003
• Equalization and clock recovery for a 2.5-10-Gb/s 2-PAM/4-PAM backplane transceiver cell. IEEE Journal of Solid-State Circuits Zerbe, J., L., Werner, C., W., Stojanovic, V., Chen, F., Wei, J., Tsang, G., Horowitz, M. A. 2003; 38 (12): 2121 - 2130
• Design of CMOS adaptive-bandwidth PLL/DLLs: a general approach. Circuits and Systems II: Analog and Digital Signal Processing IEEE Transactions on [see also Circuits and Systems II: Express Briefs, IEEE Transactions on] Kim, J., Horowitz, M., A., Wei, G. 2003; 50 (11): 860-869
• A 10-GHz global clock distribution using coupled standing-wave oscillators Solid-State Circuits IEEE Journal of O'Mahony, F., Yue, C., P., Horowitz, M., A., Wong, S., S. 2003; 38 (11): 1813-1820
• Modeling and analysis of high-speed links Stojanovic, V., Horowitz, M. 2003
• A 0.4-4-Gb/s CMOS quad transceiver cell using on-chip regulated dual-loop PLLs. IEEE Journal of Solid-State Circuits Chang, K.-Y., K., Wei, J., Huang, C., Li, S., Donnelly, K., Horowitz, M. 2003; 38 (5): 747-54
• Specifying and verifying hardware for tamper-resistant software 2003 IEEE Symposium on Security and Privacy Lie, D., Mitchell, J., Thekkath, C. A., Horowitz, M. IEEE COMPUTER SOC. 2003: 166–177

  View details for Web of Science ID 000183375200012

• 10GHz clock distribution using coupled standing-wave oscillators IEEE International Solid-State Circuits Conference O'Mahony, F., Yue, C. P., Horowitz, M., Wong, S. S. IEEE. 2003: 428-?

  View details for Web of Science ID 000185583300183

• Design of a 10GHz clock distribution network using coupled standing-wave oscillators 40th Design Automation Conference O'Mahony, F., Yue, C. P., Horowitz, M. A., Wong, S. S. ASSOC COMPUTING MACHINERY. 2003: 682–687

  View details for Web of Science ID 000184080900125

• Managing wire scaling: A circuit perspective 6th Annual International Interconnect Technology Conference Ho, R., Mai, K., Horowitz, M. IEEE. 2003: 177–179

  View details for Web of Science ID 000184465800053

• Adaptive supply serial links with sub-I-V operation and per-pin clock recovery IEEE International Solid State Circuits Conference Kim, J., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2002: 1403–13

  View details for DOI 10.1109/JSSC.2002.803937

  View details for Web of Science ID 000179027300005

• High-frequency characterization of on-chip digital interconnects IEEE JOURNAL OF SOLID-STATE CIRCUITS Kleveland, B., Qi, X. N., Madden, L., Furusawa, T., DUTTON, R. W., Horowitz, M. A., Wong, S. S. 2002; 37 (6): 716-725

  View details for Web of Science ID 000175929500006

• An efficient digital sliding controller for adaptive power-supply regulation Symposium on VLSI Circuits Kim, J., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2002: 639–47

  View details for Web of Science ID 000175198900015

• 1.6 Gb/s, 3 mW CMOS receiver for optical communication Emami-Neyestanak, A., Liu, D., Keeler, G., Helman, N., Horowitz, M., A. 2002
• Transmit pre-emphasis for high-speed time-division-multiplexed serial-link transceiver Stojanovic, V., Ginis, G., Horowitz, M., A. 2002
• Methods for true power minimization Brodersen, R., W., Horowitz, M., A., Markovic, D., Nikolic, B., Stojanovic, V. 2002
• Energy-delay tradeoffs in combinational logic using gate sizing and supply voltage optimization. ESSCIRC 2002 Stojanovic, V., Markovic, D., Nikolic, B., Horowitz, M., A., Brodersen, R., W. 2002
• Power Aware Design Methodologies. Pedram, M. 2002
• A serial-link transceiver based on 8-GSamples/s A/D and D/A converters in 0.25-mu m CMOS IEEE JOURNAL OF SOLID-STATE CIRCUITS Yang, C. K., Stojanovic, V., Modjtahedi, S., Horowitz, M. A., Ellersick, W. F. 2001; 36 (11): 1684-1692

  View details for Web of Science ID 000171893000010

• Fast low-power decoders for RAMs IEEE JOURNAL OF SOLID-STATE CIRCUITS Amrutur, B. S., Horowitz, M. A. 2001; 36 (10): 1506-1515

  View details for Web of Science ID 000171192400009

• The future of wires PROCEEDINGS OF THE IEEE Ho, R., Mai, K. W., Horowitz, M. A. 2001; 89 (4): 490-504

  View details for Web of Science ID 000168465500005

• Light field video camera Wilburn, B., S., Smulski, M., Lee, H., K., Horowitz, M., A. 2001
• Using texture mapping with mipmapping to render a VLSI layout Solomon, J., Horowitz, M. 2001
• Sampling-rate optimization of an interleaved-sampling front-end. ISCAS 2001 H., M., O., Johansson 2001
• Optimizing iterative decoding of low-density parity check codes on programmable pipelined parallel architectures Al-Rawi, G., Cioffi, J., Motwani, R., Horowitz, M. 2001
• A serial-link transceiver based on 8 GSample/s A/D and D/A converters in 0.25 mu m CMOS Ellersick, W., Yang, C., K. K., Stojanovic, V., Modjtahedi, S., Horowitz, M., A. 2001
• High-Speed Electrical Signaling in Design of High-Performance Microprocessor Circuits Horowitz, M., A. 2001
• Optimizing the mapping of low-density parity check codes on parallel decoding architectures Al-Rawi, G., Cioffi, J., Horowitz, M. 2001
• Architectural support for copy and tamper resistant software 9th International Conference on Architectural Support for Programming Languages and Operating Systems (ASPLOS_IX) Lie, D., Thekkath, C., Mitchell, M., Lincoln, P., Boneh, D., Mitchell, J., Horowitz, M. ASSOC COMPUTING MACHINERY. 2000: 168–77

  View details for Web of Science ID 000165257200017

• FLASH vs. (Simulated) FLASH: Closing the simulation loop 9th International Conference on Architectural Support for Programming Languages and Operating Systems (ASPLOS_IX) Gibson, J., Kunz, R., Ofelt, D., Horowitz, M., Hennessy, J., Heinrich, M. ASSOC COMPUTING MACHINERY. 2000: 49–58

  View details for Web of Science ID 000165257200006

• A 2.4 gb/s/pin simultaneous bidirectional parallel link with per-pin skew compensation International Solid-State Circuits Conference Yeung, E., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2000: 1619–28

  View details for Web of Science ID 000165222500012

• A variable-frequency parallel I/O interface with adaptive power-supply regulation International Solid-State Circuits Conference Wei, G. Y., Kim, J., Liu, D., Sidiropoulos, S., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2000: 1600–1610

  View details for Web of Science ID 000165222500010

• A 0.3-mu m CMOS 8-Gb/s 4-PAM serial link transceiver Symposium on VLSI Circuits Farjad-Rad, R., Yang, C. K., Horowitz, M. A., Lee, T. H. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 2000: 757–64

  View details for Web of Science ID 000087046400013

• Speed and power scaling of SRAM's IEEE JOURNAL OF SOLID-STATE CIRCUITS Amrutur, B. S., Horowitz, M. A. 2000; 35 (2): 175-185

  View details for Web of Science ID 000085393200005

• M. FLASH vs. (simulated) FLASH: closing the simulation loop Operating Systems Review Gibson, J., Kunz, R., Ofelt, D., Horowitz, M., Hennessy, J., Heinrich, M., FLASH 2000; 34 (5): 49-58
• Adaptive bandwidth DLLs and PLLs using regulated supply CMOS buffers Sidiropoulos, S., Liu, D., Kim, J., Wei, G., Horowitz, M. 2000
• Smart Memories: a modular reconfigurable architecture Mai, K., Paaske, T., Jayasena, N., Ho, R., Dally, W., J., Horowitz, M. 2000
• An eight channel 35 GSample/s CMOS timing analyzer Weinlader, D., Ron, H., Yang, C. K., Horowitz, M. 2000
• A 2.4 Gb/s/pin simultaneous bidirectional parallel link with per pin skew compensation Yeung, E., Horowitz, M. 2000
• A variable-frequency parallel I/O interface with adaptive power-supply regulation. IEEE Journal of Solid-State Circuits Wei, G., Kim, J., Liu, D., Sidiropoulos, S., Horowitz, M., A. 2000; 35 (11): 1600-10
• 64 Mbit mesochronous hybrid wave pipelined multibank DRAM macro Intelligent Memory Systems. Second International Workshop, IMS 2000. Revised Papers, Cambridge, MA, USA. Ogawa, J., Horowitz, M., A. 2000
• Timing analysis including clock skew IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS Harris, D., Horowitz, M., Liu, D. 1999; 18 (11): 1608-1618

  View details for Web of Science ID 000084031600007

• A 0.4-mu m CMOS 10-Gb/s 4-PAM pre-emphasis serial link transmitter Symposium on VLSI Circuits Farjad-Rad, R., Yang, C. K., Horowitz, M. A., Lee, T. H. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 1999: 580–85

  View details for Web of Science ID 000080039500003

• A portable digital DLL for high-speed CMOS interface circuits Symposium on VLSI Circuits Garlepp, B. W., Donnelly, K. S., Kim, J., Chau, P. S., Zerbe, J. L., Huang, C., Tran, C. V., Portmann, C. L., Stark, D., Chan, Y. F., Lee, T. H., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 1999: 632–44

  View details for Web of Science ID 000080039500010

• A fully digital, energy-efficient, adaptive power-supply regulator IEEE JOURNAL OF SOLID-STATE CIRCUITS Wei, G. Y., Horowitz, M. 1999; 34 (4): 520-528

  View details for Web of Science ID 000079369400011

• Using Partitioning to Help Convergence in the Standard-Cell Design Automation Methodology Kapadia, H., Horowitz, M. 1999
• A 50 Gb/s 32*32 CMOS crossbar chip using asymmetric serial links Chang, K. K., Chuang, S., McKeown, N., Horowitz, M. 1999
• A 0.3- mu m CMOS 8-Gb/s 4-PAM serial link transceiver Farjad-Rad, R., Yang, C. K., Horowitz, M., Lee, T. 1999
• Using partitioning to help convergence in the standard-cell design automation methodology Kapadia, H., Horowitz, M. 1999
• Scaling implications for CAD Ho, R., Mai, K., Horowitz, M. 1999
• Improving Coverage Analysis and Test Generation for Large Designs Bergmann, J., Horowitz, M. 1999
• GAD: A 12-GS/s CMOS 4-bit A/D converter for an equalized multi-level link Ellersick, W., Yang, C. K., Horowitz, M., Dally, W. 1999
• Vex - A CAD Toolbox Bergmann, J., P., Horowitz, M., A. 1999
• Low-power dividerless frequency synthesis using aperture phase detection IEEE JOURNAL OF SOLID-STATE CIRCUITS Shahani, A. R., Shaeffer, D. K., Mohan, S. S., Samavati, H., Rategh, H. R., Hershenson, M. D., Xu, M., Yue, C. P., Eddleman, D. J., Horowitz, M. A., Lee, T. N. 1998; 33 (12): 2232-2239

  View details for Web of Science ID 000077298100043

• Low-power SRAM design using half-swing pulse-mode techniques IEEE JOURNAL OF SOLID-STATE CIRCUITS Mai, K. W., Mori, T., Amrutur, B. S., Ho, R., Wilburn, B., Horowitz, M. A., Fukushi, I., Izawa, T., Mitarai, S. 1998; 33 (11): 1659-1671

  View details for Web of Science ID 000076702900010

• A replica technique for wordline and sense control in low-power SRAM's IEEE JOURNAL OF SOLID-STATE CIRCUITS Amrutur, B. S., Horowitz, M. A. 1998; 33 (8): 1208-1219

  View details for Web of Science ID 000075185400010

• A 0.5-mu m CMOS 4.0-Gbit/s serial link transceiver with data recovery using oversampling 1997 Symposium on VLSI Circuits Yang, C. K., Farjad-Rad, R., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 1998: 713–22

  View details for Web of Science ID 000073300400007

• Informing memory operations: Memory performance feedback mechanisms and their applications ACM TRANSACTIONS ON COMPUTER SYSTEMS Horowitz, M., Martonosi, M., Mowry, T. C., Smith, M. D. 1998; 16 (2): 170-205

  View details for Web of Science ID 000074989800003

• High-speed electrical signaling: Overview and limitations IEEE MICRO Horowitz, M., Yang, C. K., Sidiropoulos, S. 1998; 18 (1): 12-24

  View details for Web of Science ID 000071906600005

• A 2Gb/s Asymmetric Serial Link for High-bandwidth Packet Switches Chang, K., K.-Y, Ellersick, W., Chuang, T., S., Sidiropoulos, S., Horowitz, M., McKeown, N. 1998
• Approximate reachability with BDDs using overlapping projections 35th Design Automation Conference Govindaraju, S. G., Dill, D. L., Hu, A. J., Horowitz, M. A. ASSOC COMPUTING MACHINERY. 1998: 451–456

  View details for Web of Science ID 000077273700081

• Applications of On-Chip Samplers for Test and Measurement of Integrated Circuits Ho, R., Amrutur, B., Mai, K., Wilburn, B., Mori 1998
• A 0.4-µm CMOS 10-Gb/s 4-PAM Pre-Emphasis Serial Link Transmitter Farjad-Rad, R., Yang, C-K, K., Horowitz, M. 1998
• A semidigital dual delay-locked loop IEEE JOURNAL OF SOLID-STATE CIRCUITS Sidiropoulos, S., Horowitz, M. A. 1997; 32 (11): 1683-1692

  View details for Web of Science ID A1997YE47600008

• Skew-tolerant domino circuits IEEE JOURNAL OF SOLID-STATE CIRCUITS Harris, D., Horowitz, M. A. 1997; 32 (11): 1702-1711

  View details for Web of Science ID A1997YE47600010

• Circuit techniques for 1.5-V power supply flash memory IEEE JOURNAL OF SOLID-STATE CIRCUITS Otsuka, N., Horowitz, M. A. 1997; 32 (8): 1217-1230

  View details for Web of Science ID A1997XL40400007

• Supply and threshold voltage scaling for low power CMOS IEEE JOURNAL OF SOLID-STATE CIRCUITS GONZALEZ, R., Gordon, B. M., Horowitz, M. A. 1997; 32 (8): 1210-1216

  View details for Web of Science ID A1997XL40400006

• Optimization of hybrid JJ/CMOS memory operating temperatures 1996 Applied Superconductivity Conference Gupta, D., Amrutur, B., Terzioglu, E., Ghoshal, U., Beasley, M. R., Horowitz, M. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 1997: 3307–10

  View details for Web of Science ID A1997XH86700251

• A 700-Mb/s/pin CMOS signaling interface wing current integrating receivers IEEE JOURNAL OF SOLID-STATE CIRCUITS Sidiropoulos, S., Horowitz, M. 1997; 32 (5): 681-690

  View details for Web of Science ID A1997WV64100010

• Hardware/software co-design of the Stanford FLASH multiprocessor PROCEEDINGS OF THE IEEE Heinrich, M., Ofelt, D., Horowitz, M. A., Hennessy, J. 1997; 85 (3): 455-466

  View details for Web of Science ID A1997WN92900007

• Skew-tolerant domino circuits 1997 IEEE International Solid-State Circuits Conference Harris, D., Horowitz, M. A. I E E E. 1997: 422–423

  View details for Web of Science ID A1997BH40E00172

• Hardware fault containment in scalable shared-memory multiprocessors 24th Annual International Symposium on Computer Architecture Teodosiu, D., Baxter, J., Govil, K., Chapin, J., Rosenblum, M., Horowitz, M. ASSOC COMPUTING MACHINERY. 1997: 73–84

  View details for Web of Science ID A1997BH95B00007

• A 0.6u CMOS 4.0Gbps Transceiver with Data Recovery using Oversampling Yang, C., K, Farjad-Rad, R., Horowitz, M. 1997
• An Equalization Scheme for 10Gb/s 4-PAM Signaling over Long Cables Farjad-Rad, K., Yu, Yang, C., K., Ellersick, W., Horowitz, M., Lee, T., H. 1997
• SRT Division Architectures and Implementations Harris, D., L., Oberman, S., F., Horowitz, M., A. 1997
• A 0.6 mu m CMOS 4Gb/s transceiver with data recovery using oversampling 1997 Symposium on VLSI Circuits Yang, C. K., FarjadRad, R., Horowitz, M. JAPAN SOCIETY APPLIED PHYSICS. 1997: 71–72

  View details for Web of Science ID A1997BJ59E00031

• A semi-digital DLL with unlimited phase shift capability and 0.08-400MHz operating range 1997 IEEE International Solid-State Circuits Conference Sidiropoulos, S., Horowitz, M. I E E E. 1997: 332–333

  View details for Web of Science ID A1997BH40E00132

• Tiny Tera: A packet switch core 4th Annual Hot Interconnects Symposium McKeown, N., IZZARD, M., Mekkittikul, A., Ellersick, W., Horowitz, M. IEEE COMPUTER SOC. 1997: 26–33

  View details for Web of Science ID A1997WF58800009

• A 0.8-mu m CMOS 2.5 Gb/s oversampling receiver and transmitter for serial links 1996 International Solid-State Circuits Conference (ISSCC) Yang, C. K., Horowitz, M. A. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. 1996: 2015–23

  View details for Web of Science ID A1996VX90200023

• Energy dissipation in general purpose microprocessors IEEE JOURNAL OF SOLID-STATE CIRCUITS GONZALEZ, R., Horowitz, M. 1996; 31 (9): 1277-1284

  View details for Web of Science ID A1996VE60100006

• A 0.8 mu m CMOS 2.5Gb/s oversampled receiver for serial links 1996 IEEE International Solid-State Circuits Conference Yang, C. K., Horowitz, M. A. I E E E. 1996: 200–201

  View details for Web of Science ID A1996BF43W00077

• Validation Coverage Analysis for Complex Digital Designs Ho, R., C., Horowitz, M., A. 1996
• Informing Memory Operations: Providing Memory Performance Feedback in Modern Processors Horowitz, M., Martonosi, M., Mowry, T., C., Smith, M., D. 1996
• A 50% Noise Reduction Interface Using Low-Weight Coding Nakamura, K., Horowitz, M., A. 1996
• Informing memory operations: Providing memory performance feedback in modem processors 23rd Annual International Symposium on Computer Architecture Horowitz, M., Martonosi, M., Mowry, T. C., Smith, M. D. ASSOC COMPUTING MACHINERY. 1996: 260–270

  View details for Web of Science ID A1996BF68U00024

• A 700 Mbps/pin CMOS signalling interface using current integrating receivers 1996 Symposium on VLSI Circuits Sidiropoulos, S., Horowitz, M. I E E E. 1996: 142–143

  View details for Web of Science ID A1996BF78R00053

• A low power switching power supply for self-clocked systems 1996 International Symposium on Low Power Electronics and Design (1996 ISLPED) Wei, G. Y., Horowitz, M. I E E E. 1996: 313–317

  View details for Web of Science ID A1996BG22B00062

• Regenerative feedback repeaters for programmable interconnections IEEE JOURNAL OF SOLID-STATE CIRCUITS Dobbelaere, I., Horowitz, M., Elgamal, A. 1995; 30 (11): 1246-1253

  View details for Web of Science ID A1995TM39100013

• REGENERATIVE FEEDBACK REPEATERS FOR PROGRAMMABLE INTERCONNECTIONS 1995 IEEE International Solid-State Circuits Conference Dobbelaere, I., Horowitz, M., Elgamal, A. I E E E. 1995: 116–117

  View details for Web of Science ID A1995BD33W00041

• Array-of-arrays Architecture for Parallel Floating Point Multiplication Advanced Research in VLSI Dhanesha, H., Falakshahi, K., Horowitz, M. 1995: 150-157
• Clustered Voltage Scaling Technique for Low-Power Design Usami, K., Horowitz, M. 1995
• Informing Loads: Enabling Software to Observe and React to Memory Behavior Stanford University, Technical Report Horowitz, M., Martonosi, M., Mowry, T., C., Smith, M., D. 1995: CSL-TR-95-673
• Architecture validation for processors 22nd Annual International Symposium on Computer Architecture Ho, R. C., Yang, C. H., Horowitz, M. A., Dill, D. L. ASSOC COMPUTING MACHINERY. 1995: 404–413

  View details for Web of Science ID A1995BE13F00036

• Current integrating receivers for high speed system interconnects IEEE 1995 Custom Integrated Circuits Conference Sidiropoulos, S., Horowitz, M. I E E E. 1995: 107–110

  View details for Web of Science ID A1995BD31E00023

• TIMING ANALYSIS FOR PIECEWISE-LINEAR RSIM IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS Kao, R., Horowitz, M. 1994; 13 (12): 1498-1512

  View details for Web of Science ID A1994PT59100007

• THE PERFORMANCE IMPACT OF FLEXIBILITY IN THE STANFORD FLASH MULTIPROCESSOR 6th International Conference on Architectural Support for Programming Languages and Operating Systems Heinrich, M., KUSKIN, J., Ofelt, D., Heinlein, J., Baxter, J., Singh, J. P., Simoni, R., Gharachorloo, K., NAKAHIRA, D., Horowitz, M., Gupta, A., Rosenblum, M., Hennessy, J. ASSOC COMPUTING MACHINERY. 1994: 274–85

  View details for Web of Science ID A1994PX02700026

• INTERLEAVING - A MULTITHREADING TECHNIQUE TARGETING MULTIPROCESSORS AND WORKSTATIONS 6th International Conference on Architectural Support for Programming Languages and Operating Systems LAUDON, J., Gupta, A., Horowitz, M. ASSOC COMPUTING MACHINERY. 1994: 308–18

  View details for Web of Science ID A1994PX02700029

• SELF-TIMED LOGIC USING CURRENT-SENSING COMPLETION DETECTION (CSCD) JOURNAL OF VLSI SIGNAL PROCESSING Dean, M. E., Dill, D. L., Horowitz, M. 1994; 7 (1-2): 7-16

  View details for Web of Science ID A1994NA69100002

• THE STANFORD FLASH MULTIPROCESSOR 21st Annual International Symposium on Computer Architecture KUSKIN, J., Ofelt, D., Heinrich, M., Heinlein, J., Simoni, R., Gharachorloo, K., Chapin, J., NAKAHIRA, D., Baxter, J., Horowitz, M., Gupta, A., Rosenblum, M., Hennessy, J. I E E E, COMPUTER SOC PRESS. 1994: 302–313

  View details for Web of Science ID A1994BA93B00027

• Techniques to Reduce Power in Fast Wide Memories (CMOS SRAMS) Amrutur, B., S., Horowitz, M. 1994
• Using Partitioning to Help Convergence in the Standard-cell Design Automation Methodology Kapadia, H., Horowitz, M. 1994
• Techniques for Characterizing DRAMS with a 500 MHZ Interface Gasbarro, J., A., Horowitz, M., A. 1994
• Low-Power Digital Design Horowitz et al, M. 1994
• Evaluation of Charge Recovery Circuits and Adiabatic Switching for Low Power CMOS Design Indermaur, T., Horowitz, M. 1994
• Architectural and Implementation Tradeoffs in the Design of Multiple-Context Processors Multithreaded Computer Architectures Laudon, J., Gupta, A., Horowitz, M. Kluwer Academic Publishers. 1994: 1
• WHO WILL WIN THE WINDOWS NT SILICON SWEEPSTAKES 1994 IEEE International Solid-State Circuits Conference Horowitz, M., Slager, J., Heller, A., Tredennick, N., Riordan, T., Dobberpuhl, D., DHAM, V., MOTHERSOLE, D. I E E E. 1994: 234–235

  View details for Web of Science ID A1994BA99E00093

• A CMOS 500-MBPS PIN SYNCHRONOUS POINT-TO-POINT LINK INTERFACE 1994 Symposium on VLSI Circuits Sidiropoulos, S., Yang, C. K., Horowitz, M. I E E E. 1994: 43–44

  View details for Web of Science ID A1994BB60F00019

• PRECISE DELAY GENERATION USING COUPLED OSCILLATORS IEEE JOURNAL OF SOLID-STATE CIRCUITS Maneatis, J. G., Horowitz, M. A. 1993; 28 (12): 1273-1282

  View details for Web of Science ID A1993MX67800012

• THE DESIGN OF A HIGH-PERFORMANCE CACHE CONTROLLER - A CASE-STUDY IN ASYNCHRONOUS SYNTHESIS INTEGRATION-THE VLSI JOURNAL Nowick, S. M., Dean, M. E., Dill, D. L., Horowitz, M. 1993; 15 (3): 241-262

  View details for Web of Science ID A1993MK62900002

• NONDESTRUCTIVE READOUT ARCHITECTURE FOR A KINETIC INDUCTANCE MEMORY CELL IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY Chen, G. J., Beasley, M. R., Horowitz, M., Rosenthal, P., Whiteley, S. 1993; 3 (1): 2702-2705

  View details for Web of Science ID 000209703300218

• NONDESTRUCTIVE READOUT ARCHITECTURE FOR A KINETIC INDUCTANCE MEMORY CELL 1992 Applied Superconductivity Conference Chen, G. J., Beasley, M. R., Horowitz, M., Rosenthal, P., Whiteley, S. I E E E. 1993: 2702–2705

  View details for Web of Science ID A1993BZ49H00633

• Piecewise Linear Models for Rsim Kao, R., Horowitz, M. 1993
• PLL Design for a 500 MB/s Interface Horowitz et al, M. 1993
• Performance Analysis of a Kinetic Inductance Memory Array Chen, G., J., Beasley, M., R., Horowitz, M. 1993
• EFFICIENT SUPERSCALAR PERFORMANCE THROUGH BOOSTING SIGPLAN NOTICES Smith, M. D., Horowitz, M., Lam, M. S. 1992; 27 (9): 248-259

  View details for Web of Science ID A1992JT83700021

• CIRCUIT TECHNIQUES FOR LARGE CSEA SRAMS IEEE JOURNAL OF SOLID-STATE CIRCUITS WINGARD, D. E., Stark, D. C., Horowitz, M. A. 1992; 27 (6): 908-919

  View details for Web of Science ID A1992HV42000007

• THE STANFORD DASH MULTIPROCESSOR COMPUTER Lenoski, D., LAUDON, J., Gharachorloo, K., Weber, W. D., Gupta, A., Hennessy, J., Horowitz, M., Lam, M. S. 1992; 25 (3): 63-79

  View details for Web of Science ID A1992HH04100006

• Circuit Techniques for Large CSEA SRAM's IEEE Journal of Solid-State Circuits Wingard, D., E., Stark, D., C., Horowitz, M., A. 1992; 27 (6): 908-919
• A 500-Megabyte/s Data-Rate 4.5M DRAM Kushiyama et al, N. 1992
• Nondestructive Readout Architecture for a Kinetic Inductance Memory Cell Chen, G., J., Beasley, M., R., Rosenthal, P., R., Horowitz, M., Whiteley, S. 1992, 1993
• Clocking Strategies in High Performance Processors Horowitz et al., M. 1992
• Architectural and Implementation Tradeoffs in the Design of Multiple-Context Processors Laudon et al., J. 1992
• 500 Mbyte/sec Data-Rate 512 Kbits*9 DRAM Using a Novel I/O Interface Kushiyama et al., N. 1992
• A ZERO-OVERHEAD SELF-TIMED 160-NS 54-B CMOS DIVIDER IEEE JOURNAL OF SOLID-STATE CIRCUITS Williams, T. E., Horowitz, M. A. 1991; 26 (11): 1651-1661

  View details for Web of Science ID A1991GL70900026

• Dynamic Pointer Allocation for Scalable Cache Coherence Directories Simoni, R., Horowitz, M. 1991
• A 160NS 54BIT CMOS DIVISION IMPLEMENTATION USING SELF-TIMING AND SYMMETRICALLY OVERLAPPED SRT STAGES 10TH IEEE SYMP ON COMPUTER ARITHMETIC Williams, T. E., Horowitz, M. A. I E E E, COMPUTER SOC PRESS. 1991: 210–217

  View details for Web of Science ID A1991BT73A00028

• Asymptotic Waveform Evaluation for Circuits With Redundant DC Equations Stanford University, Technical Report Kao, R., Horowitz, M. 1991: CSL-TR-91-478
• A 160nS 54bit CMOS Division Implementation Using Self-Timing and Symmetrically Overlapped SRT Stages Williams, T., E., Horowitz, M., A. 1991
• Efficient Moment-Based Timing Analysis for Variable Accuracy Switch Level Simulation Stanford University, Technical Report Kao, R., Horowitz, M. 1991: CSL-TR-91-468
• Dynamic Pointer Allocation for Scalable Cache Coherence Directories Stanford University, Technical Report Simoni, R., Horowitz, M. 1991: CSL-TR-91-491
• Modeling the Performance of Limited Pointers Directories for Cache Coherence Simoni, R., Horowitz, M. 1991
• A 4-NS BICMOS TRANSLATION-LOOKASIDE BUFFER IEEE JOURNAL OF SOLID-STATE CIRCUITS TAMURA, L. R., Yang, T. S., WINGARD, D. E., Horowitz, M. A., Wooley, B. A. 1990; 25 (5): 1093-1101

  View details for Web of Science ID A1990EA15600008

• TECHNIQUES FOR CALCULATING CURRENTS AND VOLTAGES IN VLSI POWER-SUPPLY NETWORKS IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS Stark, D., Horowitz, M. 1990; 9 (2): 126-132

  View details for Web of Science ID A1990CJ15600002

• A Single-Chip, Functional Tester for VLSI Circuits Gasbarro, J., Horowitz, M., A., Testarossa, M. 1990
• BOOSTING BEYOND STATIC SCHEDULING IN A SUPERSCALAR PROCESSOR 17TH ANNUAL INTERNATIONAL SYMP ON COMPUTER ARCHITECTURE Smith, M. D., Lam, M. S., Horowitz, M. A. I E E E, COMPUTER SOC PRESS. 1990: 344–354

  View details for Web of Science ID A1990BQ97U00032

• Boosting Beyond Static Scheduling in a Superscalar Processor Stanford University, Technical Report Smith, M., D., Lam, M., S., Horowitz, M., A. 1990: CSL-TR-90-434
• Design of Scalable Shared-Memory Multiprocessors: the DASH Approach, Held: San Francisco, CA Lenoski et al., D. 1990
• Boosting Beyond Static Scheduling in a Superscalar Processor Horowitz, M., D. 1990
• BiCMOS Circuit Design Horowitz et al., M. 1990
• A 3.5ns, 1 Watt, ECL Register File Horowitz, M., Slamowitz, M., Rose, B., Johnson, M. 1990
• Limits on Multiple Instruction Issue Stanford University, Technical Report Smith, M., D., Johnson, M., Horowitz, M., A. 1990: CSL-TR-90-433
• AN ANALYTICAL CACHE MODEL ACM TRANSACTIONS ON COMPUTER SYSTEMS Agarwal, A., Horowitz, M., Hennessy, J. 1989; 7 (2): 184-215

  View details for Web of Science ID A1989U462500003

• SPIM - A PIPELINED 64 X 64-BIT ITERATIVE MULTIPLIER IEEE JOURNAL OF SOLID-STATE CIRCUITS Santoro, M. R., Horowitz, M. A. 1989; 24 (2): 487-493

  View details for Web of Science ID A1989T854100037

• Design of the Stanford Dash Multiprocessor Stanford University, Technical Report Lenoski, D., Laudon, J., Gharachorloo, K., Gupta, A., Hennessy, J., Horowitz, M. 1989: CSL-TR-89-403
• Limits on Multiple Instruction Issue Smith, M., Johnson, M., Horowitz, M. 1989, 1990
• IRSIM: An Incremental MOS Switch-Level Simulator, IEEE/ACM Salz, A., Horowitz, M. 1989
• Rounding Algorithms for IEEE Multipliers Santoro, M., Bewick, G., Horowitz, M. 1989
• Characteristics of Performance-Optimal Multi-Level Cache Hierarchies Przybylski, S., Horowitz, M., Hennessy, J. 1989
• SPIM: A Pipelined 64 x 64 Bit Iterative Multiplier Santoro, M., Horowitz, M. 1989, 1988
• A Single-Ended BiCMOS Sense Circuit for Digital Circuit Rosseel, G., Horowitz, M., Cline, R., Dutton, R. 1989
• The MIPS-X RISC Microprocessor Acken, J., Agarwal, A., Gulak, G., Horowitz, M., McFarling, S., Richardson, S. Kluwer Academic Publishers. 1989
• Integrated Pin Electronics for VLSI Functional Testers Gasbarro, J., Horowitz, M. 1989
• CACHE PERFORMANCE OF OPERATING SYSTEM AND MULTIPROGRAMMING WORKLOADS ACM TRANSACTIONS ON COMPUTER SYSTEMS Agarwal, A., Hennessy, J., Horowitz, M. 1988; 6 (4): 393-431

  View details for Web of Science ID A1988Q844600003

• A 4-NS 4K X 1-BIT 2-PORT BICMOS SRAM IEEE JOURNAL OF SOLID-STATE CIRCUITS Yang, T. S., Horowitz, M. A., Wooley, B. A. 1988; 23 (5): 1030-1040

  View details for Web of Science ID A1988Q243900002

• SPECIAL ISSUE ON LOGIC AND MEMORY - FOREWORD IEEE JOURNAL OF SOLID-STATE CIRCUITS Shah, A. H., Horowitz, M. A. 1988; 23 (5): 1028-1029

  View details for Web of Science ID A1988Q243900001

• Bisim: A Simulator for Custom ECL Circuits Kao, R., Alverson, R., Horowitz, M., Stark, D. 1988
• Performance Tradeoffs in Cache Design, IEEE Przybylski, S., Horowitz, M., Hennessy, J. 1988
• Scalable Directory Schemes for Cache Consistency Agarwal, A., Simoni, R., Hennessy, J., Horowitz, M. 1988
• A 4nsec 4Kx1bit Two-Port BiCMOS SRAM Yang, T. S., Horowitz, M., Wooley, B. 1988
• The Design and Testing of MIPS-X Advanced Research in VLSI, Cambridge, MA Chow, P., Horowitz, M. MIT Press. 1988: 95–114
• Generalization in Digital Functions International Neural Network Society 1988 First Annual Meeting, Boston, MA, Neural Networks Horowitz, M., Huyser et al, Karen, A. 1988; 1 (1): 101
• CHARGE-SHARING MODELS FOR SWITCH-LEVEL SIMULATION IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS Chu, C. Y., Horowitz, M. A. 1987; 6 (6): 1053-1061

  View details for Web of Science ID A1987K634400013

• MIPS-X - A 20-MIPS PEAK, 32-BIT MICROPROCESSOR WITH ON-CHIP CACHE IEEE JOURNAL OF SOLID-STATE CIRCUITS Horowitz, M., Chow, P., Stark, D., SIMONI, R. T., SALZ, A., PRZYBYLSKI, S., Hennessy, J., Gulak, G., Agarwal, A., Acken, J. M. 1987; 22 (5): 790-799

  View details for Web of Science ID A1987K182100024

• A SINGLE-CHIP LSI HIGH-SPEED FUNCTIONAL TESTER IEEE JOURNAL OF SOLID-STATE CIRCUITS MIYAMOTO, J. I., Horowitz, M. A. 1987; 22 (5): 820-828

  View details for Web of Science ID A1987K182100027

• Architectural Tradeoffs in the Design of MIPS-X Chow, P., Horowitz, M. 1987
• Toriodal Compaction of Symbolic Layouts for Regular Structures Eichenberger, P., Horowitz, M. 1987
• On-Chip Instruction Caches for High Performance Processors Horowitz, M., Agarwal et al, A. 1987
• A Static RAM as a Fault Model Evaluator Acken, J., Horowitz, M. 1987
• A Self Timing SRT Division Chip Advanced Research in VLSI, Stanford, CA Williams, T., E., Horowitz, M., Alverson, R., L., Yang, T., S. MIT Press. 1987: 75–95
• REDS: Resistance Extraction for Digital Stimulation, ACM/IEEE Stark, D., Horowitz, M. 1987
• Generating Incremental VLSI Compaction Spacing Constraints, ACM/IEEE Carpenter, C., Horowitz, M. 1987
• Active Substrate System Integration Wooley, B., Horowitz, M., Pease, R., Yang, T. 1987
• An Overview of the MIPS-X-MP Project Stanford University, Technical Report Hennessy, J., Horowitz, M. 1986: CSL-TR-86-300
• An Analytical Cache Model Stanford University, Technical Report Agarwal, A., Horowitz, M., Hennessy, J. 1986: CSL-TR-86-304
• ATUM: A New Technique for Capturing Address Traces Using Microcode Agarwal, A., Sites, R., Horowitz, M. 1986
• SRT Division Diagrams and Their Usage in Designing Custom Integrated Circuits for Division Stanford University, Technical Report Williams, T., Horowitz, M. 1986: CSL-TR-87-326
• The MIPS-X Microprocessor WESCON 1985, San Francisco, CA Horowitz, M., Chow, P. Published by Electronic Conventions Management, USA, Distributed by Western Periodicals Co, North Hollywood, CA. 1985: 6. 1
• An Automated Pressure Regulator Review of Scientific Instruments Waxman, M., Davis, H., A., Horowitz, M., Everhart, B. 1984; 55 (9): 1467-1470
• A Low Cost Laser Interferometer System for Machine Tool Applications Precision Engineering Dorsey, A., Hocken, R. 1983; 5 (1): 29-31
• Timing Models for MOS Pass Nets Horowitz, M. 1983
• Resistance Extraction from Mask Layout Data IEEE Transactions on Computer-Aided Design Horowitz, M., Dutton, R. 1983; CAD-2 (3): 145-150
• Timing Models for MOS Circuits Stanford University, Ph.D. Thesis, Dec. 1983. Also appears as Stanford University, Technical Report Horowitz, M. 1983: SEL-83-003
• Signal Delay in RC Tree Networks IEEE Transactions on Computer-Aided Design Rubinstein, J., Penfield, P., Horowitz, M. 1983; CAD-2 (3): 202-211
• A 14 BIT DUAL-RAMP DAC FOR DIGITAL-AUDIO SYSTEMS IEEE JOURNAL OF SOLID-STATE CIRCUITS Mack, W. D., Horowitz, M., BLAUSCHILD, R. A. 1982; 17 (6): 1118-1126

  View details for Web of Science ID A1982QA62700020

• A 14B PCM DAC ISSCC DIGEST OF TECHNICAL PAPERS Mack, B., Horowitz, M., BLAUSCHILD, R. 1982; 25: 86-?

  View details for Web of Science ID A1982NY99400032

• MEASUREMENT OF SERIES COLLECTOR RESISTANCE IN BIPOLAR-TRANSISTORS IEEE JOURNAL OF SOLID-STATE CIRCUITS Mack, W. D., Horowitz, M. 1982; 17 (4): 767-773

  View details for Web of Science ID A1982PB83700019

• A 14 Bit Dual Ramp DAC for Digital Audio IEEE Journal of Solid-State Circuits, Shorter version in Proceedings of International Solid-State Circuits Conference (ISSCC), San Francisco, CA Mack, W., Horowitz, M., Blauschild, R. 1982; SC-17 (6): 86-87
• Critical Anomaly in the Dielectric Constant of a Non-polar Pure Fluid Phy Rev Letters Hocken, R., Horowitz, M., Greer, S. 1976; 37 (15): 964-967