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- O'Brien School for the Maasai NFP
- O.A.B.I.: Organization for Abused and Battered Individuals
- O.C. SAFE CATS, INC.
- Oahu Society for the Prevention of Cruelty of Animals
- Oak Creek Zoological Conservatory
- Oak Crest Institute of Science
- Oak Crest Village Inc
- Oak Hill Animal Rescue Inc
- Oak Lake Art Center
- Oak Park River Forest Food Pantry
- Oak Ridge Computer Science Girls
- Oak Tree Corner Inc
- Oakland Asian Cultural Center
- Oakland Digital Arts & Literacy Center (ODALC)
- Oakland Elizabeth House
- Oakland Kids First
- Oakland Livingston Human Service Agency
- Oakland Planning & Development Corporation
- Oakland Youth Chorus
- Oaks Charlotte
- Oaks Family Care Center Inc
- Oaks Recovery
- Oakseed Ministries International
- Oasis Animal Shelter
- Oasis Compassion Agency Inc
- Oasis Counseling For Women And Children
- Oasis Ministries for Spiritual Development
- Oasis Sanctuary Foundation, Ltd.
- OATS, Inc.
- Oaxaca Street Children Grassroots, Inc.
- Obama Academy PTSA (PTA Pennsylvania Congress)
- Obat Helpers Inc
- Objective Zero Foundation
- Ocala Foursquare Church
- OccuPaws Guide Dog Association
- Ocean Blue Project
- Ocean Defenders Alliance
- Ocean Rehab Initiative Inc
- Ocean River Institute Inc
- Ocean Sanctuaries, Inc.
- Ocean State Theatre Company Inc
- Oceana, Inc.
- OceansWatch
- Ochan Self-Help Alliance, Inc.
- Octarium
- Octavio Feline Foundation Corp
- Odd Man Inn Animal Refuge
- Odessa Wildlife Rescue and Sanctuary, Inc
- ODIM - Guatemala
- Odyssey Productions, Inc
- Of One Accord
- Off the Wall Productions
- Offcenter Community Arts Project
- Offender Aid and Restoration of Arlington County (OARA), Inc.
- OfficerDown.US
- Officers' Christian Fellowship
- Ohana Rescue Inc.
- Ohio Alleycat Resource & Spay Neuter Clinic Inc
- Ohio Alliance For Arts Education
- Ohio Citizen Action
- Ohio Environmental Council
- Ohio House Rabbit Rescue Inc
- Ohio Society for the Prevention of Cruelty to Animals Inc.
- Ohio Valley Goodwill Industries Rehabilitation Center Inc
- Ohlone College Foundation
- OIC OF ANNE ARUNDEL COUNTY INC
- Ojai Valley Whale Society
- Ok Adopt A Dog
- OK Save A Dog
- Okaloosa Walton Homeless Continuum of Care Opportunity, Inc.
- Okefenokee Heritage Center Inc
- Okizu
- Oklahoma Arts Institute at Quartz Mountain
- Oklahoma Baptist Homes For Children Inc
- Oklahoma Community-Based Providers Inc
- Oklahoma Family Dog Rescue
- Oklahoma Halfway House
- Oklahoma Humane Society
- Oklahoma Interviewing Services Inc
- Oklahoma Life Skills Association: Special Kids
- Oklahoma Lions Boys Ranch
- Oklahoma Performing Arts
- Oklahomans For Equality Inc
- Olancho Aid Foundation Inc
- OLASTEO
- Olathe Civic Band Inc
- Old Church Ministries, Inc.
- Old Colony Montessori School Inc
- OLD DOG HAVEN
- Old Dominion Performance Arts Studio Inc.
- Old Friends Inc
- Old Guard Riders Inc
- Old Pine Farm Natural Lands TR Inc
- Old Savannah City Mission Inc
- Old Skool Cafe
- Oldies But Goodies (OBG) Cocker Rescue
- Olympia School District Education Foundation
- Olympic Animal Sanctuary
- Olympic Peninsula Alpaca Rescue
- Olympic Peninsula Humane Society
