Updated November 2021 - Coronavirus (COVID-19) Resource Center | JAMA

With the global coronavirus pandemic in its second year governments are still struggling to vaccinate their populations to herd immunity levels. The Delta SARS-CoV-2 variant has been a source of increased case rates and of non-severe breakthrough COVID-19 infections among vaccinated people, and investigators are working to determine if, when, and in whom additional vaccine “booster” doses would be helpful for illness prevention and pandemic control.

Browse the JAMA Network COVID-19 collection below, including Q&A's with NIAID's Anthony Fauci and Patient Information pages.

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Pediatric COVID-19 Vaccines: What Parents, Practitioners, and Policy Makers Need to Know Moss WJ, Gostin LO, Nuzzo JB JAMA November 5, 2021
Antibody Titers Before and After a Third Dose of the SARS-CoV-2 BNT162b2 Vaccine in Adults Aged ≥60 Years Eliakim-Raz N, Leibovici-Weisman Y, Stemmer A, et al. JAMA November 5, 2021
Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity Tenforde MW, Self WH, Adams K, et al. JAMA November 4, 2021
Understanding Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination Klompas M JAMA November 4, 2021
Disparities in Use of Video Telemedicine Among Patients With Limited English Proficiency During the COVID-19 Pandemic JAMA Network Open November 4, 2021
National Retail Sales of Alcohol and Cannabis During the COVID-19 Pandemic in Canada MacKillop J, Cooper A, Costello J JAMA Network Open November 4, 2021
Trials Test Mushrooms and Herbs as Anti–COVID-19 Agents Slomski A JAMA November 3, 2021
Trends in Insulin Prescribing for Patients With Diabetes During the COVID-19 Pandemic in the US Yunusa I, Love BL, Cai C, et al. JAMA Network Open November 3, 2021
Attitudes and Intentions of US Veterans Regarding COVID-19 Vaccination Jasuja GK, Meterko M, Bradshaw LD, et al. JAMA Network Open November 3, 2021
Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2 Conti MG, Terreri S, Piano Mortari E, et al. JAMA Network Open November 3, 2021
COVID-19 Baranow J JAMA November 2, 2021
The Taste of Hope Crowe EH JAMA November 2, 2021
COVID-19 Didn’t Stop Millions of Youth From Continuing to Vape Voelker R JAMA November 2, 2021
Analysis of the Effectiveness of the Ad26.COV2.S Adenoviral Vector Vaccine for Preventing COVID-19 Corchado-Garcia J, Zemmour D, Hughes T, et al. JAMA Network Open November 2, 2021
Single-Dose Ad26.COV2.S Vaccine—Room for Improvement Tehrani ZR, Sajadi MM JAMA Network Open November 2, 2021
Durability of Antibody Levels After Vaccination With mRNA SARS-CoV-2 Vaccine in Individuals With or Without Prior Infection Zhong D, Xiao S, Debes AK, et al. JAMA November 1, 2021
Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar Abu-Raddad LJ, Chemaitelly H, Ayoub HH, et al. JAMA November 1, 2021
Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination Ashrani AA, Crusan DJ, Petterson T, Bailey K, Heit JA JAMA Internal Medicine November 1, 2021
Screen Time Use Among US Adolescents During the COVID-19 Pandemic: Findings From the Adolescent Brain Cognitive Development (ABCD) Study Nagata JM, Cortez CA, Cattle CJ, et al. JAMA Pediatrics November 1, 2021

Coronavirus (COVID-19) Q&A

Conversations with Frontline Clinicians and Experts about the COVID-19 pandemic.

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Coronavirus Video Q&A JAMA Editor Howard Bauchner interviews guests about the latest developments in the global coronavirus outbreak. Watch for updates on COVID-19 diagnosis and treatment.
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Coronavirus Audio Q&A What your doctors are listening to: conversations with frontline clinicians and experts on the frontiers of the global COVID-19 pandemic, hosted by JAMA Network Editor in Chief Howard Bauchner, MD and specialist editors.

Editors' Choice
Association of Receipt of the Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barré Syndrome, February-July 2021 Woo EJ, Mba-Jonas A, Dimova RB, Alimchandani M, Zinderman CE, Nair N JAMA October 7, 2021
Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial Spyropoulos AC, Goldin M, Giannis D, et al. JAMA Internal Medicine October 7, 2021
Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial Writing Committee for the REMAP-CAP Investigators JAMA October 4, 2021
Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group JAMA July 6, 2021
Myocarditis Following Immunization With mRNA COVID-19 Vaccines in Members of the US Military Montgomery J, Ryan M, Engler R, et al. JAMA Cardiology June 29, 2021
US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021 See I, Su JR, Lale A, et al. JAMA April 30, 2021
SARS-CoV-2–Specific Antibodies in Breast Milk After COVID-19 Vaccination of Breastfeeding Women Perl SH, Uzan-Yulzari A, Klainer H, et al. JAMA April 12, 2021
Helping the Public Understand Adverse Events Associated With COVID-19 Vaccinations: Lessons Learned From Functional Neurological Disorder Kim DD, Kung CS, Perez DL JAMA Neurology April 9, 2021
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Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinical Trial INSPIRATION Investigators JAMA March 18, 2021
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Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19: A Randomized Clinical Trial López-Medina E, López P, Hurtado IC, et al. JAMA March 4, 2021
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SARS-CoV-2 Vaccines Creech CB, Walker SC, Samuels RJ JAMA February 26, 2021
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Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19 Feldstein LR, Tenforde MW, Friedman KG, et al. JAMA February 24, 2021
Effectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2 Brooks JT, Butler JC JAMA February 10, 2021
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Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children Ouldali N, Toubiana J, Antona D, et al. JAMA February 1, 2021
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Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial Gottlieb RL, Nirula A, Chen P, et al. JAMA January 21, 2021
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SARS-CoV-2 Transmission From People Without COVID-19 Symptoms Johansson MA, Quandelacy TM, Kada S, et al. JAMA Network Open January 7, 2021
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Genetic Variants of SARS-CoV-2—What Do They Mean? Lauring AS, Hodcroft EB JAMA January 6, 2021
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Therapy for Early COVID-19: A Critical Need Kim PS, Read SW, Fauci AS JAMA November 11, 2020
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COVID-19 and the Path to Immunity Stephens DS, McElrath MJ JAMA September 11, 2020
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Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group JAMA September 2, 2020
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Prevalence of SARS-CoV-2 Infection in Children Without Symptoms of Coronavirus Disease 2019 Sola AM, David AP, Rosbe KW, et al. JAMA Pediatrics August 25, 2020
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Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19) Puntmann VO, Carerj ML, Wieters I, et al. JAMA Cardiology July 27, 2020
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Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19) Wiersinga WJ, Rhodes A, Cheng AC, et al. JAMA July 10, 2020
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Is the Prone Position Helpful During Spontaneous Breathing in Patients With COVID-19? Telias I, Katira BH, Brochard L JAMA May 15, 2020
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Public Health Measures and the Reproduction Number of SARS-CoV-2 Inglesby TV JAMA May 1, 2020
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Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China 中文 (chinese) Wu Z, McGoogan JM JAMA February 24, 2020
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Characteristics of Hospitalized Patients With 2019-nCoV Pneumonia in Wuhan, China 中文 (chinese) Wang D, Hu B, Hu C, et al. JAMA February 7, 2020
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Coronavirus Infections—More Than Just the Common Cold Paules CI, Marston HD, Fauci AS JAMA January 23, 2020

Patient Information

Easy-to-understand information on COVID-19 to share with patients and their families.

Variants of SARS-CoV-2 Lauring AS, Malani PN JAMA August 13, 2021
Olfactory Loss and Olfactory Training Patel ZM JAMA Otolaryngology July 15, 2021
Return to Play After COVID-19 Infection in Children Thompson LA, Kelly MN JAMA Pediatrics June 28, 2021
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Children and COVID-19 Vaccines Thompson LA, Rasmussen SA JAMA Pediatrics June 4, 2021
Monoclonal Antibodies for COVID-19 Lloyd EC, Gandhi TN, Petty LA JAMA February 5, 2021
Necessity of 2 Doses of the Pfizer and Moderna COVID-19 Vaccines Livingston EH JAMA February 3, 2021
One Year Later, How Does COVID-19 Affect Children? Thompson LA, Rasmussen SA JAMA Pediatrics December 28, 2020
Best Practices for COVID-19–Positive or Exposed Mothers—Breastfeeding and Pumping Milk Sullivan SE, Thompson LA JAMA Pediatrics October 26, 2020
What Is Herd Immunity? Desai AN, Majumder MS JAMA October 19, 2020
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Risk of COVID-19 During Air Travel Pombal R, Hosegood I, Powell D JAMA October 1, 2020
See More Patient Information
- Current and COVID-19 Challenges With Childhood and Adolescent Sleep Stern M, Wagner MH, Thompson LA JAMA Pediatrics September 28, 2020
- Prone Positioning for Acute Respiratory Distress Syndrome (ARDS) Hadaya J, Benharash P JAMA August 21, 2020
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  Caring for Someone With COVID-19 Mortenson LY, Malani PN, Ernst RD JAMA August 13, 2020
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  What Is COVID-19? Wiersinga WJ, Prescott HC JAMA July 10, 2020
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  Convalescent Plasma and COVID-19 Malani AN, Sherbeck JP, Malani PN JAMA June 15, 2020
- What Is Anosmia? Huynh PP, Ishii LE, Ishii M JAMA June 18, 2020
- Extracorporeal Membrane Oxygenation Hadaya J, Benharash P JAMA May 28, 2020
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  Masks and Coronavirus Disease 2019 (COVID-19) Desai AN, Aronoff DM JAMA April 17, 2020
- Food Safety and COVID-19 Desai AN, Aronoff DM JAMA April 9, 2020
- Testing Individuals for Coronavirus Disease 2019 (COVID-19) Hadaya J, Schumm M, Livingston EH JAMA April 1, 2020
- Stopping the Spread of COVID-19 Desai AN, Patel P JAMA March 20, 2020
- What Does the Coronavirus Disease 2019 (COVID-19) Mean for Families? Thompson LA, Rasmussen SA JAMA Pediatrics March 13, 2020
- Medical Masks Desai AN, Mehrotra P JAMA March 4, 2020
- Coronavirus Disease 2019 and Influenza Livingston E, Bucher K, Rekito A JAMA February 26, 2020
- What Is a Pandemic? Grennan, D JAMA March 5, 2019

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