Infectious Disease CME & MOC Cases from JAMA Network

CME 1.0

Perforating Papules in a Patient With Acute Myeloid Leukemia
A woman in her 50s with relapsed refractory acute myeloid leukemia and a remote history of breast cancer was admitted for treatment of presumed fungal pneumonia based on new pulmonary nodules on imaging and elevated serum β-D-glucan levels.
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CME 1.0

Fever, Rash, and Migratory Polyarthralgias
A 24-year-old woman who worked on a farm in Connecticut developed fever, chills, vomiting, and a truncal maculopapular rash 3 weeks before presentation.
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CME 1.0

Bilateral Blurry Vision in a Human Leukocyte Antigen B27–Positive Man
A 43-year-old healthy human leukocyte antigen (HLA) B27–positive man was referred to the retina clinic with progressively worsening blurry vision in both of his eyes.
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CME 1.0

A Unified Cause of Cranial Polyneuropathy
A healthy man in his mid 30s residing in the northeastern United States was seen by his primary care physician in mid-June with a 2-week history of flulike symptoms.
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CME 1.0

Bilateral Lower Extremity Skin Eruptions in an HIV-Positive Man Receiving Pembrolizumab Monotherapy for Non–Small Cell Lung Cancer
A black man in his 30s presented for evaluation of papules and plaques on his bilateral lower extremities. Nine months before the current presentation, he was treated with intramuscular penicillin for syphilis.
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CME 1.0

Optic Nerve Swelling in a Patient With Cancer
A woman in her 60s with diffuse large B-cell lymphoma was admitted for fevers, sepsis, and Enterococcus faecalis urinary tract infection in the context of bilateral malignant ureteral obstruction.
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CME 1.0

An Erysipeloid Cutaneous Eruption in a Woman With Advanced Breast Cancer
A woman in her 60s presented with a 3-month history of a progressive, asymptomatic cutaneous eruption on her chest and back.
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CME 1.0

A Teenage Girl With Aseptic Meningitis and Unilateral Blurry Vision
A 14-year-old girl presented to the emergency department after experiencing 2 weeks of fever, malaise, photophobia, phonophobia, headache, nausea, vomiting, and neck stiffness.
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CME 1.0

Gray-Violet Plaque in an Immunocompromised Girl
A 4-year-old girl with newly diagnosed acute lymphocytic leukemia, receiving her initial course of chemotherapy with vincristine, daunorubicin, and methotrexate, developed a painful lesion on her left triceps.
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CME 1.0

A Woman With Purple Macules on the Legs
A 30-year-old woman presented with widespread, erythematous, purpuric macules and papules on the abdomen and extremities. The eruption had been present for approximately 8 months and consisted of asymptomatic, self-resolving, and continuously appearing macules and papules.
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