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Appendix 1. Data table for Figure 1. Age-adjusted cancer death rates, by sex and year: United States, 1999 to 2018
Year Total Male Female
Number Deaths per 100,000 Number Deaths per 100,000 Number Deaths per 100,000
1999 549,838 200.8 285,832 251.9 264,006 167.6
2000 553,091 199.6 286,082 248.9 267,009 167.6
2001 553,768 196.5 287,075 244.5 266,693 165.1
2002 557,271 194.3 288,768 240.9 268,503 163.7
2003 556,902 190.9 287,990 235.1 268,912 161.5
2004 553,888 186.8 286,830 229.5 267,058 158.2
2005 559,312 185.1 290,422 227.2 268,890 156.7
2006 559,888 181.8 290,069 221.7 269,819 154.7
2007 562,875 179.3 292,857 218.8 270,018 152.3
2008 565,469 176.4 295,259 214.9 270,210 149.6
2009 567,628 173.5 296,763 210.9 270,865 147.4
2010 574,743 172.8 301,037 209.9 273,706 146.7
2011 576,691 169.0 302,231 204.0 274,460 144.0
2012 582,623 166.5 305,670 200.3 276,953 142.1
2013 584,881 163.2 307,559 196.0 277,322 139.5
2014 591,700 161.2 311,296 192.9 280,404 138.1
2015 595,930 158.5 313,818 189.2 282,112 135.9
2016 598,038 155.8 314,571 185.4 283,467 134.0
2017 599,108 152.5 315,147 181.1 283,961 131.4
2018 599,274 149.1 315,553 176.8 283,721 128.6

NOTES: Deaths were classified using the International Classification of Diseases, 10th Revision. Cancer deaths were identified using underlying cause-of-death codes C00-C97 (malignant neoplasms). Rates were age-adjusted to the 2000 US standard population. Healthy People objectives are available at www.healthypeople.gov.external icon

SOURCE: National Center for Health Statistics, National Vital Statistics System, Mortality Data.

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Appendix 2. Data table for Figure 2. Age-adjusted cancer death rates and change in rates, by cancer type: United States, 1999 to 2018
Type 1999 2018 [Period of Trend] and Annual Percent Change Total Percent Change Average Annual Percent Change
Number % Deaths per 100,000 Number % Deaths per 100,000 1 2 3 4 1999–2018 1999–2018 2014–2018
All cancers 549,838 100% 200.8 599,274 100% 149.1 [1999–2015]
-1.5		 [2015–2018]
-2.1		 -26% -1.6 -1.9
Oral cavity and pharynx 7,486 1% 2.7 10,158 2% 2.5 [1999–2009]
-1.2		 [2009–2018]
0.5		 -7% -0.4 0.5
Esophagus 11,918 2% 4.4 15,419 3% 3.8 [1999–2005]
0.1 NS		 [2005–2018]
-1.1		 -14% -0.7 -1.1
Stomach 12,711 2% 4.6 11,043 2% 2.8 [1999–2006]
-3.3		 [2006–2018]
-2.2		 -39% -2.6 -2.2
Colon and rectum 57,222 10% 20.9 52,163 9% 13.1 [1999–2002]
-2.0		 [2002–2005]
-3.8		 [2005–2013]
-2.5		 [2013–2018]
-1.8		 -38% -2.4 -1.8
Liver and intrahepatic bile duct 12,382 2% 4.5 27,686 5% 6.7 [1999–2008]
2.3		 [2008–2012]
3.5		 [2012–2016]
1.3		 [2016–2018]
-0.3 NS		 49% 2.0 0.5 NS
Pancreas 29,082 5% 10.6 44,915 7% 11.0 [1999–2018]
0.3		 4% 0.2 0.2
Larynx 3,815 1% 1.4 3,777 1% 0.9 [1999–2018]
-2.2		 -36% -2.2 -2.2
Lung and bronchus 152,063 28% 55.4 142,081 24% 34.8 [1999–2002]
-0.3 NS		 [2002–2010]
-1.8		 [2010–2015]
-3.2		 [2015–2018]
-5.1		 -37% -2.5 -4.6
Melanoma of Skin 7,215 1% 2.6 8,199 1% 2.1 [1999–2013]
0.1 NS		 [2013–2018]
-5.9		 -19% -1.5 -5.9
Female breast 41,144 7% 26.6 42,466 7% 19.7 [1999–2002]
-1.3		 [2002–2007]
-2.2		 [2007–2015]
-1.6		 [2015–2018]
-0.9		 -26% -1.6 -1.1
Cervix uteri 4,205 1% 2.8 4,138 1% 2.2 [1999–2004]
-3.2		 [2004–2018]
-0.8		 -21% -1.4 -0.8
Corpus uteri and uterus, not otherwise specified 6,468 1% 4.1 11,238 2% 5.0 [1999–2008]
0.3 NS		 [2008–2018]
2.0		 22% 1.2 2.0
Ovary 13,627 2% 8.8 13,748 2% 6.3 [1999–2004]
0.0 NS		 [2004–2018]
-2.4		 -28% -1.7 -2.3
Prostate 31,729 6% 31.3 31,489 5% 18.8 [1999–2013]
-3.5		 [2013–2018]
-0.5 NS		 -40% -2.7 -0.5 NS
Kidney and renal pelvis 11,116 2% 4.1 14,134 2% 3.5 [1999–2001]
2.1 NS		 [2001–2015]
-0.9		 [2015–2018]
-2.4		 -15% -0.8 -2.0
Bladder 11,911 2% 4.4 16,641 3% 4.2 [1999–2013]
0.1 NS		 [2013–2018]
-1.1		 -5% -0.2 -1.1
Brain and other nervous system 12,765 2% 4.6 17,127 3% 4.4 [1999–2006]
-1.2		 [2006–2018]
0.4		 -4% -0.2 NS 0.4
Non-Hodgkin lymphoma 22,802 4% 8.3 20,287 3% 5.1 [1999–2005]
-3.3		 [2005–2018]
-2.3		 -39% -2.6 -2.3
Leukemia 21,014 4% 7.6 23,359 4% 6.0 [1999–2012]
-1.0		 [2012–2018]
-2.2		 -21% -1.3 -2.2
Myeloma 10,565 2% 3.9 12,471 2% 3.1 [1999–2009]
-1.6		 [2009–2014]
0.1 NS		 [2014–2018]
-2.1		 -20% -1.2 -2.1

NOTES: Deaths were classified using the International Classification of Diseases, 10th Revision. Cancer deaths were identified using underlying cause-of-death codes C00-C97 (malignant neoplasms). Rates were age-adjusted to the 2000 US standard population. Annual percentage change and average annual percentage change in rates were estimated with Joinpoint regression. Up to 3 joinpoints could be specified, for a maximum of 4 trend periods. Trends were significantly different than zero (P<.05) unless indicated as not significant (NS), i.e., the trend was stable.

SOURCE: National Center for Health Statistics, National Vital Statistics System, Mortality Data.

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Appendix 3. Data table for Figure 3. Age-adjusted cancer death rates, by characteristics and cancer type: United States, 2018
Characteristic All cancers combined Lung and bronchus Female breast Colorectal Prostate
Number Deaths per 100,000 Number Deaths per 100,000 Number Deaths per 100,000 Number Deaths per 100,000 Number Deaths per 100,000
Overall 599,274 149.1 142,081 34.8 42,466 19.7 52,163 13.1 31,489 18.8
Sex
Male 315,553 176.8 76,234 41.7 27,964 15.8 31,489 18.8
Female 283,721 128.6 65,847 29.3 42,466 19.7 24,199 11.0
Race/ethnicity
non-Hispanic white 463,971 154.4 116,646 38.0 31,242 19.9 38,723 13.2 23,218 17.8
non-Hispanic black 70,014 173.8 15,025 36.9 6,453 27.6 6,924 17.3 5,214 37.3
American Indian/Alaska Native (non-Hispanic) 3,305 128.1 798 30.6 198 14.0 329 13.1 161 16.4
Asian/Pacific Islander (non-Hispanic) 18,643 93.4 3,760 19.1 1,420 12.3 1,796 8.9 704 9.2
Hispanic 42,066 107.4 5,545 15.1 3,072 13.4 4,264 10.8 2,115 15.1
Census Region
Northeast 107,182 144.6 24,906 33.3 7,675 19.0 9,025 12.3 5,391 17.6
Midwest 136,455 157.8 34,321 39.1 9,303 20.3 11,798 13.8 6,953 19.3
South 233,223 153.9 58,825 38.0 16,484 20.4 20,627 13.8 11,628 18.5
West 122,414 136.2 24,029 26.5 9,004 18.8 10,713 12.0 7,517 19.8
Rural/urban status
Urban 489,633 145.8 112,947 33.2 35,759 19.7 42,162 12.7 25,931 18.7
Rural 109,641 166.2 29,134 42.9 6,707 20.0 10,001 15.5 5,558 19.2

NOTES: Deaths were classified using the International Classification of Diseases, 10th Revision. Cancer deaths were identified using underlying cause-of-death codes C00-C97 (malignant neoplasms). Rates were age-adjusted to the 2000 US standard population. Rural/urban status was based on county of residence, classified using the 2013 NCHS Urban-Rural Classification Scheme for Counties. Healthy People objectives are available at www.healthypeople.gov.external icon

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Appendix 4. Data table for Figure 4. Age-specific cancer death rates: United States, 2018
Age Group Number Rate
<15 1,220 2.0
15–19 621 2.9
20–24 750 3.4
25–29 1,297 5.5
30–34 2,387 10.8
35–39 4,153 19.3
40–44 6,487 32.9
45–49 12,908 62.2
50–54 24,393 116.8
55–59 46,603 212.4
60–64 67,344 331.2
65–69 80,591 471.7
70–74 88,465 659.9
75–79 84,340 910.1
80–84 74,454 1,215.1
≥85 103,252 1,577.7
Unknown age 9

NOTES: Deaths were classified using the International Classification of Diseases, 10th Revision. Cancer deaths were identified using underlying cause-of-death codes C00-C97 (malignant neoplasms).

SOURCE: National Center for Health Statistics, National Vital Statistics System, Mortality Data.

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Page last reviewed: May 29, 2020
Content source: Division of Cancer Prevention and Control, Centers for Disease Control and Prevention