SENS Research Foundation was established in 2009; over 10 years later and we are leading the charge to Reimagine Aging.
Our annual conference gathers together scientists and startups from around the globe who are accelerating rejuvenation therapies to repair the damage of aging.
May 13-15, Berlin
Listen to Edward James Olmos describe why SENS is invaluable to defeating aging.
Dr. Aubrey de Grey and SRF have joined Instagram @sensresearchfoundation
SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. We are redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists.
May 13-15, Berlin.
The conference is focused on the cellular and molecular repair of age-related damage as the basis of therapies to bring aging under full medical control.
2019’s event attracted nearly 500 participants from over 30 countries. Undoing Aging 2021 will once again bring together global pioneers who are leading the charge in maintaining and restoring full health in old age.
To accommodate the exciting growth of the rejuvenation biotechnology industry, Undoing Aging 2021 will host a dedicated forum and exhibition space for startups to present themselves to prospective investors and partners — while a special “Rejuvenation Now” session will highlight the human rejuvenation therapies that are currently in clinical trials or are available today.
Nearly half of the mammalian genome is long and short interspersed virus-like repetitive elements (LINEs and SINEs), which spread through the process of retrotransposition.
SRF is funding a study to test the impact of the removal of cells damaged by LINE/SINE reactivation on healthspan and lifespan, via the creation of a special transgenic mouse in the lab of Dr. Andrei Gudkov at the Roswell Park Comprehensive Cancer Center.
Recognizing the challenges that will face high school biology teachers in the upcoming academic year, SRF has launched the Research Integrated Science Education (RISE) Program to provide distance-friendly lessons that integrate experimental design and data interpretation concepts into the high school biology curriculum.
SRF spin-off Revel Pharmaceuticals, a privately held biotechnology company creating therapeutics to reverse and repair damage that results from aging – particularly extracellular crosslinks – has announced recent additions to its Board of Directors and Scientific Advisory Board.
The removal of damaged material from within atherosclerotic plaques (“fatty streaks”) to restore cardiovascular health is a key component of SENS, now being developed for the clinic by SRF ally Underdog Pharmaceuticals. Exciting new preclinical results from another group using this strategy have recently been published in ACS Nano.
Dr. Jonathan Clark’s SRF-funded group at the Babraham Institute have published two new papers showing that the current model in which aging tissues lose elasticity due to the accumulation of stable crosslinks is not the full story – results which will be crucial to reversing that deterioration.
“Senescent” cells progressively restrict the body’s capacity for tissue renewal and secrete factors that disrupt local tissue homeostasis. A new study provides proof-of-concept that ablation of these cells can delay — and potentially contribute to the reversal of — age-related tissue dysfunction and disease.
In conversation with Adam Ford, Dr. Aubrey de Grey explains how recent extraordinary results with senolytic drugs suggest that the milestone of “Robust Mouse Rejuvenation” – a key step towards comprehensively undoing human aging – could be as little as three years away.
SENS Research Foundation is now able to accept donations in Zcash (ZEC), in addition to eight other major cryptocurrencies: Bitcoin, Bitcoin Cash, Ethereum, Ethereum Classic, Litecoin, 0x (ZRX), USD Coin, and BAT. Visit the donate page for more information!
We’re grateful to cryptocurrency pioneer Vitalik Buterin for once again choosing to support SENS Research Foundation, with a generous donation of $350,000 in Ethereum towards our End of Year campaign to Reimagine Aging.
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