On the one-hour seventh season premiere, Sheldon and Penny bond in Leonard's absence, but it's Sheldon's feelings that are crushed when Leonard returns from the North Sea. Guest star REGINA KING returns as Mrs. Davis, the University's Director of Employee Relations.

On the second part of the one-hour seventh season premiere, Raj gets consoled about his ex-girlfriend and Howard's relationship with his mother causes an unusual threat to his masculinity. KEVIN SUSSMAN returns as Stuart, the comic book store owner.

When the entire gang competes in a cutthroat scavenger hunt designed by Raj that tests their science knowledge and street smarts, it brings out the best -- and worst -- in everyone.

After Amy ruins one of Sheldon's favorite movies -- Raiders of the Lost Ark -- he gets defensive, seeking revenge. Meanwhile, Leonard discovers a way to get Penny to do anything; and Raj and Stuart create online dating profiles.

Sheldon must decide how much "Amy time" is too much after she takes a job at his university, and their relationship is put to the test. Meanwhile, Howard finds himself sleeping on Raj's couch after a fight with Bernadette.

Sheldon's latest scientific breakthrough makes him feel like a fraud -- and threatens to haunt him forever. Meanwhile, Howard's romantic gesture to Bernadette causes Penny to step up her game with Leonard.

Sheldon feels slighted when Professor Proton (recurring guest star BOB NEWHART) seeks advice from Leonard instead of him, and he seeks revenge by befriending a rival science TV host, BILL NYE (guest starring as Himself). Meanwhile, Raj gets jealous when Howard crashes "girls' night."

Leonard tries to keep Sheldon from overreacting when a past mistake comes to light, but Sheldon punishes Leonard by making him "walk a mile in his shoes." Meanwhile, Penny confronts Raj's ex-girlfriend, Lucy (guest star KATE MICUCCI).

An upset Sheldon protests when the entire gang drags him to Mrs. Wolowitz's house for Thanksgiving. Meanwhile, Penny and Leonard must deal with a mistake from her past.

Leonard and Amy help Sheldon cope with the shame he's feeling after his accidental contribution to science is disproved. Meanwhile, Raj must stay with Howard and Bernadette for a week. IRA FLATOW guest stars as Himself.

While Sheldon is away in Texas, everyone gathers to decorate the apartment Christmas tree, and imagines what their lives would be like if they had never met Sheldon.

When Penny's big acting break on NCIS is a bust, Leonard struggles to help her, which results in Penny asking Leonard a bold relationship question. Meanwhile, Sheldon tries to learn how to be funny and Raj tries to work on his "game" before talking to girls.

When Sheldon is forced to take a vacation, he tries to relax, but instead spends a lot of time with Penny after she quits her job. Meanwhile, Leonard struggles to be supportive of Penny and Bernadette seeks Stuart's help in replacing one of Howard's comic books.

After they guys can't get Comic-Con tickets, Sheldon decides to hold his own convention, and winds up spending a wild night with JAMES EARL JONES (guest starring as himself). Meanwhile, the girls see if they can act like "grown-ups." Star Wars icon CARRIE FISHER makes a cameo appearance as well.

Love is in the air when Amy convinces Sheldon to join her (as well as Howard and Bernadette) for a romantic weekend in Napa Valley to celebrate Valentine's Day. Meanwhile, Leonard and Penny must rush Raj's dog to the vet.

When Leonard buys a dining room table, it causes Sheldon to reevaluate the changes in his life. Meanwhile, Wolowitz is offered a chance to go back to space and Bernadette struggles with whether or not to encourage him.

Howard invites Sheldon to travel to Houston with him in an attempt to improve their friendship, while Penny's offered an embarrassing role and Raj asks Amy for help with a girl.

When Sheldon visits his mom (recurring guest star LAURIE METCALF) in Houston, he is forced to confront a new reality. Meanwhile, Raj's "Murder Mystery" party starts some fights within the gang.

While Raj is wracked with guilt over dating two women at the same time and Penny is wrestling with whether to take a role in a cheesy movie, Amy must help Sheldon through the even greater hell of choosing between two gaming systems.

Sheldon faces a personal crisis after deciding he's wasting his time with String Theory. Meanwhile, a double date between Raj, Emily and the Wolowitzes ends in embarrassment for Howard.

Leonard tries to help Sheldon free his mind by reinstating "Anything Can Happen Thursday," but when Sheldon tries to be spontaneous, it leads to unexpected friction between Penny, Amy and Bernadette. Meanwhile, Raj seeks Howard's help in preparing for a date with Emily.

May the "Fourth" Be With You! Professor Proton helps Sheldon cope with grief, while Leonard turns a relationship milestone into a competition with Penny. Meanwhile Amy and Bernadette make a "Star Wars Day gift for the guys.

A horrible day at work prompts Penny to evaluate her life choices -- including taking a big step with Leonard. Meanwhile, Howard and Bernadette struggle to care for Mrs. Wolowitz, and Raj gets relationship advice from Sheldon.

With his entire world changing around him, Sheldon is forced to confront an uncertain future and considers a major move in the seventh season finale. Meanwhile, Raj and Emily take it to the next level, and Mrs. Wolowitz's injury is a major headache for Howard and Bernadette. Recurring guest star CHRISTINE BARANSKI returns as Leonard's mother, Beverly Hofstadter.

Highlights of the Q&A with the cast and creators

Cast members discuss the best romantic moments from Season 6.

Join The Big Bang Theory's executive producers and writers at the Comic Con 2013 Panel, discussing the creative process for the first time.

On the sixth season premiere, Howard discovers that he can't escape his mother -- even in space! Caught in an argument between Bernadette and his mom (recurring guest voice CAROL ANN SUSI), Howard deals with woman trouble from the International Space Station. Back on earth, meanwhile, Raj faces his loneliness, by turning his existence as a third wheel into an art form.

When Sheldon learns that Penny is thinking about breaking up with Leonard, he tries to intervene. But Sheldon is no good at keeping secrets. Meanwhile, Howard is being picked on in space by the other astronauts (guest stars PASHA LYCHNIKOFF and MIKE MASSIMINO).

While the pressures of being in space starts to take its toll on Howard, Amy feels threatened when Sheldon hires a young female assistant, Alex (guest star MARGO HARSHMAN).

When Howard returns from space, he doesn't get the hero's welcome he expected. Meanwhile, Game Night turns into a battle of the sexes.

The gang celebrates Halloween at Stuart's comic book store. Meanwhile Leonard and Penny discover a new spark in their relationship when he seduces her with science. And while Howard can't stop talking about space, it takes iconic astronaut BUZZ ALDRIN (guest starring as himself) to get him grounded again.

Sheldon's tenuous relationship with renowned scientist STEPHEN HAWKING is threatened by a game of "Words with Friends," while Penny secretly enrolls in a class at the local college.

Pressured by Bernadette, Howard comes to terms with moving out of his mother's house. Meanwhile, Sheldon, who's caught in the middle of a feud between his "girlfriend" Amy and good friend WIL WHEATON, goes to Penny for advice. Star Trek's LeVAR BURTON guest stars.

Howard and Raj try to get to the bottom of why Sheldon disappears every afternoon at 2:45. Meanwhile, Leonard and Penny wrestle with jealousy in their relationship.

When the University reassigns Sheldon's (unused) parking spot to Howard, the ensuing turf battle affects the whole gang.

Sheldon plays nursemaid to a sick Amy, while Howard attempts to bond with his father-in-law (guest star CASEY SANDER) on an upcoming fishing trip.

Sheldon unwillingly revisits some Christmas memories during a lively game of Dungeons and Dragons, while Penny, Bernadette and Amy try to find the perfect girl for Raj when he joins the girls for ladies night.

Sheldon is accused of sexual harassment at the Univesity and winds up dragging Leonard, Raj and Howard into the fray. Southland's REGINA KING guest stars as the University's Director of Employee Relations.

While the guys take a road trip to a comic book convention in Bakersfield dressed as characters from Star Trek: The Next Generation, Leonard's car is stolen. Meanwhile, the girls stay home and try to appreciate the world of comics.

Outraged that he's being forced to work with his university nemesis, Barry Kripke (guest star JOHN ROSS BOWIE), Sheldon faces a crisis of conscience. Meanwhile, Howard and Raj spend a thousand dollars on action figures of themselves.

A fight between Leonard and Sheldon drives Leonard to finally move in with Penny -- not realizing how the shift will affect Penny and Amy's living arrangements. Meanwhile, Raj takes care of Mrs. Wolowitz while Howard is away.

While the guys try to give their significant others the perfect Valentine's Day, Raj and Stuart throw a lonely people party at the comic book store.

After a terrible date, Raj vows to never leave his apartment again. Meanwhile, Penny actually impresses Sheldon with her acting skills.

Back to school! Leonard, Sheldon and Howard try to advance the cause of women in science by speaking with junior high girls about their future careers, while Raj plans his date with Lucy (guest star KATE MICUCCI).

When Howard finds a letter from his father, he's forced to confront his past, struggling with whether or not he should open it. And Leonard and Penny throw a "grown-up" cocktail party at the apartment.

Let the battle begin! Leonard, Sheldon and Raj fight for tenure at the University -- and the competition heats up when the girls get involved!

Sheldon feels lost after one of his favorite TV shows gets canceled too soon, so Amy tries to help him get over his compulsive need for closure. Meanwhile, Raj discovers a secret about his new love interest, Lucy.

Sheldon and Leonard hire Professor Proton (guest star BOB NEWHART), the host of their favorite childhood TV show, to perform. Also, Howard and Bernadette run into trouble babysitting Raj's dog.

When the girls' trip to Vegas falls through, the guys invite them to play Dungeons & Dragons -- causing Sheldon and Amy's relationship to take an unexpected turn. Meanwhile, Raj and Lucy go on a very awkward date.

When Leonard is offered an exciting new job opportunity overseas, Sheldon grows very jealous and Penny is thrown for a loop. Meanwhile, Raj pushes Lucy a little too far in their relationship on the sixth season finale.

The fifth season premiere picks up where the fourth season finale left off as the gang deals with the aftermath of Penny and Raj's night together. While Penny worries that she's screwed things up permanently with her friends, Sheldon takes command of the paintball team. Emmy® nominee CHRISTINE BARANSKI (The Good Wife) reprises her role as Leonard's emotionally distant mother.

A battle of wills between Sheldon and Penny leaves Amy caught in the middle, while Leonard tries to spice up his long-distance relationship with Priya (recurring guest star AARTI MANN), who has moved back to India.

Leonard attends a co-worker's wedding as Amy's date. Meanwhile, Howard tries to convince Bernadette to live with his mom after they get married by suggesting a trial run with the two of them staying with his mom over the weekend.

When Raj is upset he's the only one of the four guys who is not in a relationship, Penny sets out to find the perfect date, introducing him to Emily (guest star KATIE LeCLERC -- Switched at Birth) a girl he can actually talk to!

Sheldon's old nemesis, WIL WHEATON (guest starring as Himself), returns and invites everyone to a housewarming party. Sheldon threatens to "defriend" Leonard if he attends. But when he hears that BRENT SPINER (guest starring as Himself), the actor who played Commander Data, will be there, Sheldon decides to go to the party after all... only to discover new levels of treachery. Meanwhile, Howard gets an out-of-this-world opportunity that Bernadette reacts to strongly.

Craving a little motherly love, Sheldon competes with the gang for his mother's attention when she comes to visit. LAURIE METCALF reprises her role as Sheldon's mother, Mary.

A cute comic book artist (guest star COURTNEY FORD) puts Leonard's relationship with Priya to the test; while Sheldon, getting into the spirit of Halloween, tries to scare the guys.

Amy is heartbroken when Bernadette and Penny go shopping for wedding dresses without her.

Can friends with benefits still be friends without? Leonard and Penny try hanging out alone, while Sheldon must overcome his fear of birds.

Sheldon becomes jealous and considers taking his relationship with Amy to the next level when Stuart (guest star KEVIN SUSSMAN) from the comic book store asks her out on a date.

Leonard must face his fears after being contacted by his high school tormentor (guest star LANCE BARBER), while Penny realizes that she might have been a bully herself.

Sheldon gets in trouble with Amy when he isn't impressed by her recent accomplishment, and it's up to Penny to teach him how to be a better boyfriend. Howard, meanwhile, must come to grips with Bernadette's dislike of children.

The possibility of Leonard and Penny getting back together could prove disastrous when Leonard offers Penny a spur of the moment invitation to a romantic dinner for two on the 100th episode of the series.

Leonard and Penny experiment with dating again by "beta testing" their relationship, while Raj develops a peculiar relationship with his phone's virtual assistant.

Sheldon's selfish demands force Leonard to reconsider their friendship. Could this be the end of The Roommate Agreement? Meanwhile, Howard tries to pick his astronaut nickname, but NASA astronaut MIKE MASSIMINO (guest starring as himself) has other ideas.

When Sheldon is forced to take a vacation by the university, he goes to work with Amy in her neurobiology lab. Meanwhile, Bernadette wants Howard to sign a pre-nuptial agreement.

When a corner office at the University opens up, Sheldon must compete for it with his office nemesis, Barry Kripke. Meanwhile, a personal gift from Amy makes Penny uncomfortable.

Sheldon's life is turned upside-down after his barber becomes hospitalized. Now, that there's been a change in his routine, Sheldon finds himself re-evaluating his entire life. Meanwhile, astronaut training causes Howard to rethink his decision to go into space.

It's on...like Alderaan, when the guys plan a weekend Star Wars gaming marathon! But when Sheldon chooses the guys-only weekend over a weekend with Amy to visit her aunt, he is destined to feel the force!

It's a dream come true for Sheldon when he has a close encounter with his hero, Mr. Spock. Legendary sci-fi icon LEONARD NIMOY guest stars, lending his voice to a unique reprisal of his three-time Emmy®-nominated Star Trek role.

When Wolowitz gets tow work with world-renowned scientist STEPHEN HAWKING (guest starring as Himself), Sheldon is willing to do anything to meet his hero.

Howard's wedding plans are in jeopardy after the guys (and Wil Wheaton) throw him a bachelor party. After details of his sexual history are leaked online, Bernadette reconsiders marrying Howard.

When NASA reschedules Howard's mission and puts his wedding plans in jeopardy, he's forced to face his fears and Bernadette's dad (guest star CASEY SANDER). Meanwhile, Leonard says something surprising to Penny in the bedroom.

Howard Wolowitz crosses over into the final frontiers of space...and marriage on the fifth season finale. When Howard and Bernadette decide they want to be married before his NASA space launch, the gang rushes to put on a wedding. NASA Astronaut Mike Massimino guest stars as Himself.

On the fourth season premiere, Penny (series star KALEY CUOCO) finds herself along for the ride on Sheldon's (series star JIM PARSONS) first date ever. Meanwhile, Wolowitz (series star SIMON HELBERG) finds a new use for a robotic arm. MAYIM BIALIK guest stars as Sheldon's date, Amy Fowler.

When Sheldon realizes he won't live long enough to download his consciousness into a robot body, he attempts to extend his lifespan. Apple Co-Founder STEVE WOZNIAK guest stars as Himself.

The guys are concerned as Sheldon searches for an alternative to human companionship after he and Amy (MAYIM BIALIK) break up. LAURIE METCALF reprises her role as Sheldon's mother.

An embarrassing secret of Wolowitz's comes to light, while Sheldon and Raj have a small war at work. Battlestar Galactica's KATEE SACKHOFF and Star Trek's GEORGE TAKEI guest star as themselves as Wolowitz's love gurus. MELISSA RAUCH reprises her role as Howard's girlfriend, Bernadette.

Leonard realizes he's the only one without a girlfriend, while Sheldon wants to get rid of his.

A visit from Raj's sister (guest star AARTI MANKAD) creates tension among the guys -- especially when Leonard keeps an affair secret from Sheldon, Howard and Raj.

When an FBI agent (guest star ELIZA DUSHKU) interviews the guys for Wolowitz's security clearance, Sheldon's answers during the screening, put Wolowitz's clearance in jeopardy.

When the guys camp in line for a screening, their plans are thwarted by Sheldon's greatest nemesis, WIL WHEATON (guest starring as himself). Meanwhile, Penny and Bernadette invite Amy to her first slumber party.

Penny asks Leonard to lie to her father, Wyatt (guest star KEITH CARRADINE), while Howard, Raj and Bernadette pull an all-nighter at a telescope.

Amy finds she has sexual feelings for Penny's ex, Zack (guest star BRIAN THOMAS SMITH) while Koothrappali and Wolowitz try to prove who would be the better superhero.

The guys find a "super" use for Penny's new boyfriend, Zack, when they enter a costume contest as the Justice League.

Leonard's idea for a smartphone app derails his friendship with Sheldon as they fight for control of the project.

Tension runs high when everyone is staying at the same hotel for a science event and Bernadette runs into her ex-boyfriend (guest star RICK FOX, three-time NBA champion with the Los Angeles Lakers).

Sheldon wants Penny to give him acting lessons, hoping that they will help him become a better teacher. Meanwhile, Koothrappali fantasizes about his best friend's girlfriend.

A wealthy donor to the university makes Leonard consider how far he's willing to go for the sake of science. JESSICA WALTER (Arrested Development) guest stars as the widowed benefactress and JOSHUA MALINA (The West Wing) guest stars as the University President.

As Wolowitz contemplates taking things with Bernadette to the next level, he must choose between his girlfriend and his mother. Meanwhile, Leonard rekindles his relationship with Raj's sister, Priya.

When the gang starts hanging out at Raj's and Sheldon realizes it's actually Leonard who is the center of their social group, Sheldon decides to get a new group of friends.

Leonard must choose between his new girlfriend, Priya, and his friendship with Penny. Meanwhile, Howard drives Sheldon crazy with a magic trick.

When someone hacks Sheldon's online gaming account, the guys go on a quest to find the culprit.

Sheldon and Amy experiment on their friends by spreading gossip, while Howard takes a big step in his relationship with Bernadette.

Priya uses her lawyer skills to pick apart the roommate agreement...and put Sheldon in his place. Meanwhile, the girls take Sheldon dancing.

Raj attempts to cure his social anxiety disorder of talking to women, while Penny uses Bernadette to spy on Leonard and his girlfriend.

When Howard finally breaks the news to his mom that he's engaged to Bernadette, it lands her in the hospital.

When Bernadette receives her Ph.D., the guys take joy in reminding an emasculated Wolowitz that he is the only one in their group who isn't a doctor. Meanwhile, Koothrappali becomes Sheldon's new roommate after hearing Leonard and Priya engaging in a Star Trek bedroom fantasy, on the fourth season finale.

On the third season premiere, Sheldon (series star JIM PARSONS) flees back to Texas in disgrace when he learns that the guys tampered with his arctic expedition data -- forcing his friends to follow him, and threatening Leonard's (series star JOHNNY GALECKI) hopes for a romantic encounter with Penny (series star KALEY CUOCO).

Leonard and Penny struggle to recover from an awkward first hookup, while Sheldon and Howard (series star SIMON HELBERG) stake their best comic books on a bet to determine the species of a cricket. LEWIS BLACK guest stars as an entymologist who settles the high-stakes bet.

Howard and Raj (series star KUNAL NAYYAR) visit a Goth nightclub to pick up women, while Sheldon attempts to build a better Penny using chocolate-based behavior modification.

Raj must find a new job or be sent back to India. Sheldon, however, has a solution -- which leaves Leonard and Penny dealing with Howard as third wheel.

While Sheldon settles a score with his nemesis, Star Trek: The Next Generation's WIL WHEATON (guest starring as himself), Wolowitz begs Leonard to get Penny to set him up with one of her friends.

Sheldon teaches Leonard how to understand football, while a kite-fighting incident threatens Howard and Raj's friendship.

Sheldon plays the peacemaker when an argument between Leonard and Penny proves "inconvenient" to him.

With Leonard, Howard and Raj away camping in the desert, an injured Penny has only Sheldon to rely on.

After he's humiliated on National Public Radio, Sheldon vows to destroy Kripke (guest star JOHN ROSS BOWIE), and the guys help Sheldon exact his revenge. Meanwhile, Wolowitz tries not to destroy his new relationship with Bernadette (guest star MELISSA RAUCH). KATEE SACKHOFF (Battlestar Galactica) makes a cameo as Wolowitz's dream girl.

Sheldon takes on his greatest challenge when he attempts to help Penny understand physics, and Wolowitz becomes jealous when Leonard starts hanging out with his new girlfriend.

A visit from Leonard's mother (guest star CHRISTINE BARANSKI) delights Sheldon and horrifies Leonard.

While Sheldon and Koothrappali attend a university mixer, Leonard is upset to discover that Penny believes in psychics. DANICA McKELLAR (The Wonder Years) guest stars as the object of Raj's attraction.

When their apartment is robbed, Leonard and Sheldon turn to their friends to create a state-of-the-art security system -- and Sheldon struggles to cope.

Suffering from a case of "physicist's block," Sheldon's search for the answer to a physics problem leads him to work at the Cheesecake Factory with Penny.

It's Valentine's Day, and Leonard can only bring one guest on a trip to see CERN's Large Hadron Collider (the world's largest and highest energy particle accelerator) in Switzerland. Will it be Sheldon or Penny?

Sheldon misses his chance to meet comic book legend STAN LEE (as himself) when he winds up in traffic court after he gets a ticket because of Penny.

When the guys find a rare movie prop ring from The Lord of the Rings at a garage sale, it threatens to tear them apart -- forcing them to choose the ring or their friendship.

Sheldon's friends come to his aid when his fear of public speaking stands between him and a coveted award.

A fight between Leonard and Penny threatens their relationship, while Sheldon battles WIL WHEATON (guest starring as Himself) in bowling.

When Leonard and Penny aren't speaking, Sheldon goes to extremes to keep them both happy and gets caught in a lie.

Leonard and Sheldon compete for the attention of a famous female physicist -- Dr. Elizabeth Plimpton (guest star JUDY GREER).