Fel d 1
Fel d 1 is a protein that in cats is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes.
Fel d 1, produced largely in cat saliva and sebaceous glands, is the primary allergen present on cats and kittens. Fel d 1 is also produced by cat skin itself. The protein is of an unknown function to the animal but causes an IgG or IgE reaction in sensitive humans (either as an allergic or asthmatic response). Removal of soft surfaces in the home (carpet, furniture), frequent washings of bed linens, HEPA filters and even washing cats has been proven to reduce the amounts of Fel d 1 present in the home.
Neutered males produce Fel d 1 in levels similar to females (both intact and spayed females produce Fel d 1 in similar levels). Even though females and neutered males produce Fel d 1 in lower levels, they still produce enough to cause allergic symptoms in sensitive individuals.
Structure
The complete quaternary structure of Fel d 1 has been determined. The allergen is a tetrameric glycoprotein consisting of two disulfide-linked heterodimers of [chains 1 and 2. Fel d 1 chains 1 and 2 share structural similarity with uteroglobin, a secretoglobin superfamily member; chain 2 is a glycoprotein with N-linked oligosaccharides. Both chains share an all alpha-helical structure.
Fel
Fel is a commune in the Orne department in north-western France.
See also
References
Podcasts:
Fool With You
Verse 1:
At the movies one night,
Sportin apple bottom jeans and them gucci boots,
Saw you walkin my way,
With some M&M;'s and a Mountain Dew,
The way you switch ya booty when you walk by,
Ya handcuffed to a nigga but its alright,
Girl before ya go (go),
Slide ya number on the low,
I wanna-
Chorus*:
Fool With You,
(are you down with that, with no strings attached, I wanna)
Fool With You,
(keep it on the low, he ain't gotta know, I wanna)
Fool With You,
(gotsta put it down, when yo man ain't around, I wanna)
Fool With You
Verse 2:
I see ya sittin real close,
Got ya man on the side but we doin the most,
Put my hand on yo thigh,
So I can feel underneath your clothes,
Ain't nobody knowin and it's so hot,
Got a nigga goin baby don't stop,
You'll be more than just a lover,
But for now we undercover
*Chorus*
Verse 3:
Can sneak out the exit door,
Go to the movies so he won't know,
When we sip on the cris,
I'll give you some of this,
Be back before the credits roll,
You know (you know), I know (I know), that you want me to grab that waist,
'cause I know (I know), you know (you know), that I gotta get a taste
I really really gotta-
*Chorus*
Verse 4:
(Baby tonight I'll freak ya body right), I'm gonna freak ya body right,
(I'm lovin them lips them hips them sexy thighs), Those sexy thighs,
(Meet at my place so we ain't gotta hide), We ain't gotta hide so I can, (Fool With You), Fool With Your body honey