In a blog post on Wednesday, Neuralink said its second human recipient is using the brain chip to play Counter-Strike 2 and develop 3D designs in CAD software. "Alex" was given the brain chip last month to help restore his autonomy after a spinal cord injury. PCMag reports: Like the first Neuralink patient, Noland Arbaugh, Alex has also been using the brain chip to play his favorite computer games, such as Counter-Strike 2. Before, Alex had to use a mouth-operated controller, called a QuadStick, to play the first-person shooter. But even then, the controller limited him to only moving or aiming his weapon at a single time, never simultaneously like a normal Counter-Strike player. In other words, Alex had to essentially switch back and forth between the mouse and keyboard functions while playing the game. But thanks to Neuralink, he can now aim with the implant, and simultaneously move while using the QuadStick. [...]

In the blog post, Neuralink also addressed a problem the company faced when placing the chip in Arbaugh, the first patient. Despite a successful surgery, about 85% of the thread-based electrodes attached to his brain later became displaced, undermining the full potential of the chip to read neural signals. Although Arbaugh can still use his implant effectively, Neuralink wanted to avoid a repeat with Alex. In response, the company developed several "mitigations," which include reducing the chance of an air pocket forming during surgery and placing the implant deeper into the brain tissue. "Promisingly, we have observed no thread retraction in our second participant," the company said of Alex.

Whether Alex's implant outperforms the brain chip in Arbaugh was left unclear. In the meantime, Neuralink says it's working on ways to enhance the controls on the technology "to deliver full mouse and video game controller functionality." "Additionally, we plan to enable the Link [brain chip] to interact with the physical world, allowing users to feed themselves and move more independently by controlling a robotic arm or their wheelchair," the company said. You can watch Alex playing Counter-Strike 2 on YouTube.

A growing body of scientific evidence shows that microplastics are accumulating in critical human organs, including the brain, leading researchers to call for more urgent actions to rein in plastic pollution. From a report: Studies have detected tiny shards and specks of plastics in human lungs, placentas, reproductive organs, livers, kidneys, knee and elbow joints, blood vessels and bone marrow. Given the research findings, "it is now imperative to declare a global emergency" to deal with plastic pollution, said Sedat Gundogdu, who studies microplastics at Cukurova University in Turkey. Humans are exposed to microplastics -- defined as fragments smaller than 5mm in diameter -- and the chemicals used to make plastics from widespread plastic pollution in air, water and even food.

The health hazards of microplastics within the human body are not yet well-known. Recent studies are just beginning to suggest they could increase the risk of various conditions such as oxidative stress, which can lead to cell damage and inflammation, as well as cardiovascular disease. Animal studies have also linked microplastics to fertility issues, various cancers, a disrupted endocrine and immune system, and impaired learning and memory.

NASA astronauts Butch Wilmore and Suni Williams are facing challenges returning to Earth due to compatibility issues between their Boeing-designed spacesuits and SpaceX's Dragon spacecraft. Inc. Magazine reports: The space suits in question are the "intra-vehicular activity" outfits now worn by astronauts. They're simpler than the bulky extra-vehicular space suits used on space walks, and are designed to keep astronauts safe in the capsule in the very unlikely case there's a problem that causes the capsule's atmosphere to be lost. The problem is simple: Should Butch and Suni need to fly back aboard SpaceX's vehicle, their suits won't fit in Dragon's seats. [...]

Boeing and SpaceX suits evolved under totally different design sensibilities. If Boeing and NASA deem Starliner unsafe for humans to fly home in, Butch and Suni must head earthward aboard a SpaceX Dragon, but their suits won't be able to plug into Dragon's systems. Like trying to plug an essentially outdated USB A socket into an iPhone's charge port, the suit connectors have different shapes, styles, and functions. The suits themselves have different systems that integrate with their own capsules for purposes like air leak checks during pre-flight testing.

So if an emergency situation presents itself and astronauts have to come back to Earth before proper plans are finalized, Butch and Suni will have to return inside the cargo section of a Dragon space capsule "unsuited," according to NASA leadership who spoke on the matter in a press conference last week. Other plans include flying up suitable Dragon-connecting space suits for the two astronauts on a later mission, should Starliner be deemed incapable of bringing them back.

"A new front has opened in the longstanding debate over how fast the universe is expanding," writes Science magazine: For years astronomers have argued over a gulf between the expansion rate as measured from galaxies in the local universe and as calculated from studies of the cosmic microwave background (CMB), the afterglow of the Big Bang. The disparity was so large and persistent that some astronomers thought the standard theory of the universe might have to be tweaked. But over the past week, results from NASA's new James Webb Space Telescope orbiting observatory suggest the problem may be more mundane: some systematic error in the strategies used to measure the distance to nearby galaxies.

"The evidence based on these data does not suggest the need for additional physics," says Wendy Freedman of the University of Chicago, who leads [the Carnegie-Chicago Hubble Program, or CCHP] that calculated the expansion rate from JWST data using three different galactic distance measurements and released the results on the arXiv preprint server. (The papers have not yet been peer reviewed.) The methods disagreed about the expansion rate, known as the Hubble constant, or H0, and two were close to the CMB prediction.
Specifically, the team used JWST to measure the distance to 10 local galaxies using three stars with a predictable brightness: Cepheids, the brightest red giant stars, and carbon stars. Science notes that the last two methods "agreed to about 1%, but differed from the Cepheid-based distance by 2.5% to 4%." Combining all three methods the team derived a value "just shy of 70 km/s per Mpc," according to the article — leading the University of Chicago's Freedman to say "There's something systematic in the measurements. Until we can establish unambiguously where the issue lies in the nearby universe, we can't be claiming that there's additional physics in the distant universe."

But the controversy continues, according to Adam Riess of Johns Hopkins University (leader of a team of Hubble Constant researchers known as SH0ES). Riess points out that other teams have used JWST to measure distances with all three methods separately and have come up with values closer to the original SH0ES result. He also questions why CCHP excluded data from telescopes other than JWST. "I don't see a compelling justification for excluding the data they do," he says.
Thanks to long-time Slashdot reader sciencehabit for sharing the article.

Citizen scientists from NASA's Backyard Worlds: Planet 9 project discovered a hypervelocity object, CWISE J1249, moving fast enough to escape the Milky Way. "This hypervelocity object is the first such object found with the mass similar to or less than that of a small star," reports NASA's Science Editorial Team, suggesting the object may have originated from a binary star system or a globular cluster. From the report: A few years ago, longtime Backyard Worlds citizen scientists Martin Kabatnik, Thomas P. Bickle, and Dan Caselden spotted a faint, fast-moving object called CWISE J124909.08+362116.0, marching across their screens in the WISE images. Follow-up observations with several ground-based telescopes helped scientists confirm the discovery and characterize the object. These citizen scientists are now co-authors on the team's study about this discovery published in the Astrophysical Journal Letters (a pre-print version is available here). CWISE J1249 is zooming out of the Milky Way at about 1 million miles per hour. But it also stands out for its low mass, which makes it difficult to classify as a celestial object. It could be a low-mass star, or if it doesn't steadily fuse hydrogen in its core, it would be considered a brown dwarf, putting it somewhere between a gas giant planet and a star.

Ordinary brown dwarfs are not that rare. Backyard Worlds: Planet 9 volunteers have discovered more than 4,000 of them! But none of the others are known to be on their way out of the galaxy. This new object has yet another unique property. Data obtained with the W. M. Keck Observatory in Maunakea, Hawaii, show that it has much less iron and other metals than other stars and brown dwarfs. This unusual composition suggests that CWISE J1249 is quite old, likely from one of the first generations of stars in our galaxy. Why does this object move at such high speed? One hypothesis is that CWISE J1249 originally came from a binary system with a white dwarf, which exploded as a supernova when it pulled off too much material from its companion. Another possibility is that it came from a tightly bound cluster of stars called a globular cluster, and a chance meeting with a pair of black holes sent it soaring away.

America's top colleges and finance-industry recruiters have long had their eye on teenage whiz-kids who compete in a prestigious high-school math contest. Now, allegations of cheating are threatening to disrupt it. WSJ: Online leaks of tests for the country's best-known math contest -- the 74-year-old American Mathematics Competition -- are upsetting students who have spent years preparing for the exams. Ahead of the coming school year and test season, angry parents and math coaches have pushed the contest's administrator to tighten controls. The incident is the latest byproduct of a high-pressure college-admissions race that can lead students to look for any edge to get ahead.

[...] As early as elementary school, students interested in flexing their math knowledge beyond what is taught in school can participate in math clubs and competitions. Each year, more than 300,000 students through high school participate in the AMC's first round of multiple-choice tests. Several thousand top performers are invited to sit for a higher-level test, and from there, around 600 compete in national "math olympiads." The top six math students in the nation then represent the U.S. internationally; the U.S. won its ninth International Mathematical Olympiad title this summer.

Murmurs about cheating in the AMC have circulated for a few years, participants say, but reached critical levels during the past school year. The entirety of exams at each level of the competition were available online hours or days before students sat for the tests, a spokeswoman for the Mathematical Association of America confirmed. Testing sites in the U.S. and abroad receive the questions online early to give proctors time to print them out for the in-person exams.

NASA chief Bill Nelson didn't mince words about the agency's budget crunch. "You can't put 10 pounds of potatoes in a five-pound sack," he told ArsTechnica in an interview, addressing $4.7 billion in cuts over two years.

To scientists fretting over axed missions, Nelson offered a frank "I feel your pain." The Mars Sample Return's ballooning $11 billion price tag and 2040 timeline forced a reset. "We pulled the plug," Nelson admitted, but he's banking on cheaper, creative alternatives emerging by year's end.

The moon rover Viper got the chop too, blowing its budget by 40%. "There comes a limit," Nelson said, defending the tough call. Viper lunar rover project was "running 40 percent over budget." He defended these decisions as necessary given the $2 billion cut to science funding alone. The cuts stem from the Fiscal Responsibility Act. Nelson expressed hope for a "reprieve" in fiscal year 2026, but noted uncertainty due to another looming debt ceiling issue.

AT&T and Verizon are urging the FCC to reject SpaceX's plan to offer cellular service with T-Mobile, arguing that it would cause harmful interference to terrestrial mobile networks. Ars Technica reports: Filings urging the Federal Communications Commission to deny SpaceX's request for a waiver were submitted by AT&T and Verizon this week. The plan by SpaceX's Starlink division also faces opposition from satellite companies EchoStar (which owns Dish and Hughes) and Omnispace. SpaceX and T-Mobile plan to offer Supplemental Coverage from Space (SCS) for T-Mobile's cellular network using SpaceX satellites. As part of that plan, SpaceX is seeking a waiver of FCC rules regarding out-of-band emission limits.

AT&T's petition to deny the SpaceX waiver request said the FCC's "recent SCS order appropriately recognized that SCS deployments should not present any risk to the vital terrestrial mobile broadband networks upon which millions of Americans rely today. The Commission authorized SCS as secondary to terrestrial mobile service, correctly explaining that the SCS framework must 'retain service quality of terrestrial networks, protect spectrum usage rights, and minimize the risk of harmful interference.'" AT&T said SpaceX's requested "ninefold increase" to the allowable power flux-density limits for out-of-band emissions "would cause unacceptable harmful interference to incumbent terrestrial mobile operations. Specifically, AT&T's technical analysis shows that SpaceX's proposal would cause an 18% average reduction in network downlink throughput in an operational and representative AT&T PCS C Block market deployment." Verizon's opposition to the waiver request similarly said that SpaceX's proposal "would subject incumbent, primary terrestrial licensee operations in adjacent bands to harmful interference." Wireless phone performance will suffer, Verizon said [...]. SpaceX and T-Mobile told FCC staff that their plan will not harm other wireless operations and predicted that competitors will make misleading claims. SpaceX also argued that the FCC's emissions limit is too strict and should be changed.

An anonymous reader quotes a report from the New York Times: Melted capsules. Cloudy insulin. Pills that may no longer work. Doctors and pharmacists say the scorching temperatures enveloping the country could be endangering people's health in an unexpected way: by overheating their medications. Millions of Americans now receive their prescription medications through mail-order shipments, either for convenience or because their health plans require it. But the temperatures inside the cargo areas of delivery trucks can reach 150 degrees Fahrenheit in the summer, according to drivers -- far exceeding the range of 68 to 77 degrees recommended by the national organization that sets standards for drug handling.

Mail-order pharmacies say that their packaging is weather resistant and that they take special precautions when medication "requires specific temperature control." But in a study published last year, independent pharmaceutical researchers who embedded data-logging thermometers inside simulated shipments found that the packages had spent more than two-thirds of their transit time outside the appropriate temperature range, "regardless of the shipping method, carrier, or season." Extreme temperatures can alter the components in many medications, from pancreatic enzymes to the thyroid replacement drug levothyroxine to oral contraceptives, medical experts say.

Dr. Mike Ren, a primary care physician and an assistant professor in the department of family and community medicine at the Baylor College of Medicine, said that liquid medications like insulin or AUVI-Q, the epinephrine injection for allergic reactions, are often at heightened risk of degradation because excessive heat exposure can cause the evaporation of liquid components that were compounded at precise ratios. Aerosolized medications, too, are uniquely vulnerable because of the risk of pressure changes in the canister. "Doctors recommend picking up your prescriptions at a local pharmacy whenever possible during hot summer months, particularly if your medication is liquid or aerosolized," notes the report. "If you are enrolled in an insurance program that requires using a mail-order pharmacy, ask for an exception during the summer or, at the very least, contact the on-call pharmacist at the mail-order company to get more information about shipping practices and to ask for temperature-controlled packaging. You should do this even if the drug does not require refrigeration."

Once you do get your medication, you should make sure to preserve it in a cool, dry environment, away from direct sunlight. If you're flying, your prescriptions should be stored in your carry-on bag. They should never be left in a parked car.

sciencehabit shares a report from Science Magazine: A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far. The DNA of Lepidosiren paradoxa comprises a staggering 91 billion chemical letters or "bases," 30 times as many as the human genome, researchers report today in Nature. However, those 91 billion bases of DNA only contain about the same number of genes that humans have -- roughly 20,000 -- with the rest consisting of noncoding, perhaps even "junk" DNA. By comparing this genome with those of other lungfishes, the researchers determined that L. paradoxa adds the equivalent of a human genome to its DNA every 10 million years.

Ars Technica's John Timmer reports: [T]he International Astronomical Union has a resolution that calls for a "Lunar Celestial Reference System" and "Lunar Coordinate Time" to handle things there. On Monday, two researchers at the National institute of Standards and Technology, Neil Ashby and Bijunath Patla, did the math to show how this might work. [...] Ashby and Patla worked on developing a system where anything can be calculated in reference to the center of mass of the Earth/Moon system. Or, as they put it in the paper, their mathematical system "enables us to compare clock rates on the Moon and cislunar Lagrange points with respect to clocks on Earth by using a metric appropriate for a locally freely falling frame such as the center of mass of the Earth-Moon system in the Sun's gravitational field." What does this look like? Well, a lot of deriving equations. The paper's body has 55 of them, and there are another 67 in the appendices. So, a lot of the paper ends up looking like this.

Things get complicated because there are so many factors to consider. There are tidal effects from the Sun and other planets. Anything on the surface of the Earth or Moon is moving due to rotation; other objects are moving while in orbit. The gravitational influence on time will depend on where an object is located. So, there's a lot to keep track of. Ashby and Patla don't have to take everything into account in all circumstances. Some of these factors are so small they'll only be detectable with an extremely high-precision clock. Others tend to cancel each other out. Still, using their system, they're able to calculate that an object near the surface of the Moon will pick up an extra 56 microseconds every day, which is a problem in situations where we may be relying on measuring time with nanosecond precision. And the researchers say that their approach, while focused on the Earth/Moon system, is still generalizable. Which means that it should be possible to modify it and create a frame of reference that would work on both Earth and anywhere else in the Solar System. Which, given the pace at which we've sent things beyond low-Earth orbit, is probably a healthy amount of future-proofing. The findings have been published in the Astronomical Journal. A National Institute of Standards and Technology (NIST) press release announcing the work can be found here.

An anonymous reader quotes a report from The Guardian: The study, which tracked thousands of different molecules in people aged 25 to 75, detected two major waves of age-related changes at around ages 44 and again at 60. The findings could explain why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages. [...] The research tracked 108 volunteers, who submitted blood and stool samples and skin, oral and nasal swabs every few months for between one and nearly seven years. Researchers assessed 135,000 different molecules (RNA, proteins and metabolites) and microbes (the bacteria, viruses and fungi living in the guts and on the skin of the participants).

The abundance of most molecules and microbes did not shift in a gradual, chronological fashion. When the scientists looked for clusters of molecules with the largest shifts, they found these transformations tended to occur when people were in their mid-40s and early 60s. The mid-40s aging spike was unexpected and initially assumed to be a result of perimenopausal changes in women skewing results for the whole group. But the data revealed similar shifts were happening in men in their mid-40s, too. "This suggests that while menopause or perimenopause may contribute to the changes observed in women in their mid-40s, there are likely other, more significant factors influencing these changes in both men and women," said Dr Xiaotao Shen, a former postdoctoral scholar at Stanford medical school and first author of the study who is now based at Nanyang Technological University Singapore.

The first wave of changes included molecules linked to cardiovascular disease and the ability to metabolize caffeine, alcohol and lipids. The second wave of changes included molecules involved in immune regulation, carbohydrate metabolism and kidney function. Molecules linked to skin and muscle ageing changed at both time points. Previous research suggested that a later spike in aging may occur around the age of 78, but the latest study could not confirm this because the oldest participants were 75. The pattern fits with previous evidence that the risk of many age-related diseases does not increase incrementally, with Alzheimer's and cardiovascular disease risk showing a steep uptick after 60. It is also possible that some of the changes could be linked to lifestyle or behavioral factors. For instance, the change in alcohol metabolism could result from an uptick in consumption in people's mid-40s, which can be a stressful period of life. The findings have been published in the journal Nature Aging.

An anonymous reader quotes a report from Wired: Florida's ban on cultivated meat is being challenged in federal court in a lawsuit that was filed yesterday. The case is being brought by the cultivated meat firm Upside Foods and the Institute of Justice (IJ), a nonprofit public interest law firm. Florida governor Ron DeSantis signed the legislation making the sale of cultivated meat illegal in Florida on May 1, and the bill came into effect on July 1. Alabama passed a similar bill banning cultivated meat that will come into effect from October 1. The case brought by Upside Foods and the IJ argues that Florida's ban is unconstitutional in three different ways. First, they argue, the ban violates theSupremacy Clause that gives federal law priority over state law in certain instances. The court case argues that the Florida ban violates two different provisions in the Federal Meat Inspection Act and Poultry Products Inspection Act.

The legal complaint (PDF) also alleges that the ban violates theCommerce Clause, which gives the US Congress exclusive power to regulate interstate commerce. The IJ argues that the Commerce Clause restricts states from enacting laws that unduly restrict interstate commerce, and that Florida's ban in its current form has the effect of discriminating against it. "Florida's law has nothing to do with protecting health and safety," said IJ senior attorney Paul Sherman in a press conference today. "It is a transparent example of economic protectionism." Sherman said that Upside Foods and the IJ would also apply for a preliminary injunction that would allow the company to sell cultivated meat in Florida while the legal challenge is still ongoing. The complaint says that Upside had planned to distribute its cultivated chicken at Art Basel in Miami in early December 2024. The company protested the Florida ban by holding a tasting of its chicken on June 27 in Miami, shortly before the ban came into effect. Sherman said that the Alabama ban was also "in our sights" but that the IJ had targeted the Florida law as it came into effect before the Alabama ban. "We're hoping we'll be able to get a quick ruling [in Florida] on a preliminary injunction there," and use that as a precedent to challenge the Alabama ban, he said. "Consumers should decide what kind of meat they want to buy and feed their families -- not politicians," said the Good Food Institute (GFI), a nonprofit focused on advancing alternative proteins and which is serving as a consulting consul in this case. "This lawsuit seeks to protect these consumer rights, along with the rights of companies to compete in a fair and open marketplace."

An anonymous reader quotes a report from The Guardian: The World Health Organization (WHO) is poised to scrap controversial drinking water guidelines proposed for two toxic PFAS "forever chemicals." The move follows allegations that the process of developing the figures was corrupted by industry-linked researchers aiming to undercut strict new US PFAS limits and weaken standards in the developing world. Many independent scientists charged that the proposed WHO drinking water guidelines for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) were weak, did not fully protect human health, ignored credible research, and were far above limits set by regulators in the US and EU. The guidelines would have allowed far more PFAS in drinking water than what is allowed by the US Environmental Protection Agency.

Though the earlier guidelines were drafts, and proposed rules all go through a revision process, the WHO is conducting an entirely new review of scientific literature and disbanded the panel of scientists who developed the draft guidelines. It established a new panel with fewer industry-linked scientists and more regulatory officials, moves that have not happened in other revisions, said Betsy Southerland, a former EPA manager in the agency's water division. "This is unprecedented, but the WHO got unprecedented criticism," Southerland said. The WHO told the Guardian in a statement that the moves are part of "an ongoing process" and will include guidelines for other PFAS compounds.

Scientists critical of the limits charged that the WHO ignored high-quality research to create a sense of doubt about the science around PFAS. EPA and EU regulators carried out an exhaustive literature review to find all human and animal studies, and used the best of those papers to establish their limits, Southerland said. The WHO, however, ignored all human studies and determined most animal studies were "too flawed" to use, Southerland said. The organization concluded there was not enough research to set health-based guidelines, which she called a "shocking decision." "There is far more health data for these chemicals than has ever been available for any pollutant in the history of the WHO," Southerland said. Instead, the WHO largely based its guidelines on its review of technological research, but ignored most of those studies as well, Southerland said. The body concluded filtration systems could reliably remove PFOA and PFOS at 100ppt, even though US water utilities remove it below four ppt. The decisions bear industry's prints, researchers say.

An anonymous reader quotes a report from Ars Technica: SpaceX will fly the first-ever human spaceflight over the Earth's poles, possibly before the end of this year, the company announced Monday. The private Crew Dragon mission will be led by a Chinese-born cryptocurrency entrepreneur named Chun Wang, and he will be joined by a polar explorer, a roboticist, and a filmmaker whom he has befriended in recent years. The "Fram2" mission, named after the Norwegian research ship Fram, will launch into a polar corridor from SpaceX's launch facilities in Florida and fly directly over the north and south poles. The three-to-five day mission is being timed to fly over Antarctica near the summer solstice in the Southern Hemisphere, to afford maximum lighting.

The four-person crew will fly, fittingly, aboard Crew Dragon Endurance, which is named after Ernest Shackleton's famous ship that was trapped in the Antarctic ice and eventually sunk there about a century ago. The spacecraft will be fitted with a cupola for both photography and filming. This will be SpaceX's third free-flying mission aboard Crew Dragon, following the Inspiration4 mission funded and commanded by US entrepreneur Jared Isaacman in 2021, and his forthcoming Polaris Dawn mission which may launch later this month. In an interview, Wang said he modeled the Fram2 mission's crew and public outreach programs on the template established by Isaacman.