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Good NewsOxford COVID-19 vaccine prompts immune response among adults old and young, AstraZeneca says (reuters.com)

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[–]Hundsheimer_Berge 358 points359 points  (306 children)

Assuming we go forward with this, (and other vaccines) I can't help but wonder what the normalization metrics will be.

When can social distancing go away, when can masks come off. etc

[–]spidereater 136 points137 points  (40 children)

It probably depends on the data on the ground. Once you vaccinate the elderly/vulnerable and healthcare workers you probably start working down the demographics. We should see hospitalizations and deaths begin to drop. That likely causes governments to begin opening things up. If illness continues to drop they will continue to open things up. Once things like theatres are open it will be more a matter of personal comfort. I probably won’t be going to the movies in 2021 but some people will. Case numbers that we are uncomfortable with today may be common once deaths have dropped dramatically.

[–]Hundsheimer_Berge 93 points94 points  (20 children)

what I find peculiar is nobody is talking hard numbers. "When daily infection rates drop to XX"
"When daily deaths are down to YY"

Nobody seems to want to define those thresholds.

[–]spidereater 63 points64 points  (0 children)

Originally the threat was about overwhelming the hospitals. It seems like hospitalizations and deaths as a fraction of cases have dropped as we’ve gotten better at testing and better at treating the illness and also reallocated resources to shift hospital capacity. So a problematic case rate April becomes a manageable case rate in October. Once people over 80 are vaccinated the manageable case rate will change again. I’m sure nobody wants to commit to a number only to be criticized later when that number actually becomes manageable.

[–]TheCookie_Momster 33 points34 points  (3 children)

Our school district won’t go back to in person until the weekly average cases is less than 7 per 100,000. We were recently in the 20s

[–][deleted] 8 points9 points  (0 children)

That sounds very reasonable. I’m not thrilled with our district’s plan. Our school district is in hybrid when weekly average cases are 50-200 per 100,000. Under 50 it’s full-time, in-person. They barely made it to switch from remote to hybrid last week and the numbers shot up so they have to return to remote this week.

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    [–]ronreadingpa 9 points10 points  (2 children)

    The goalposts keep moving. Shutdowns were only to be for a couple of weeks to allow the medical system to catch up; flatten the curve.

    While many will justify the various changes along the way, it's still frustrating for many who want a definitive answer as to what everything will reopen again without restrictions...

    Truth is no one really knows. Some areas continue to open while others are locking down again. My view is 2021 may be an improvement over 2020, but don't count on full opening until 2022 at the earliest.

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      [–]TonyNickels 11 points12 points  (3 children)

      Are you not expecting to have access to the vaccine in 2021? I see no reason to not go to large gatherings if you are vaccinated.

      [–]lynypixie 5 points6 points  (0 children)

      My husband and I both work in a hospital, so we will be in the first wave of vaccination (especially me, as I work directly with patients). We might loosen up faster. But right now, that day looks very far because of the chaos of health care. The second wave is hitting us like a brick because we didn’t get to relax much from the first one. We are now super understaffed and overcrowded with patients. I came home crying this weekend. And I work in a green unit, not even a covid infested one.

      [–]agoddamnlegend 11 points12 points  (11 children)

      You plan to avoid crowds for all of 2021? That seems kind of crazy tbh. No way it takes that long to get a vaccine if you’re in a “major” country.

      [–]spidereater 5 points6 points  (3 children)

      There are plenty of things less crowded than a movie theatre. I got through the summer without feeling too stifled.

      [–]agoddamnlegend 16 points17 points  (2 children)

      Movie theater, bar, concert, sporting event... whatever your hobby is. No reason we can’t get back to normal at some point in 2021 once you get the vaccine. To say in October 2020, with a couple vaccines on the horizon, that you already plan to avoid crowds all of next year is being really over cautious imo

      [–]princessjemmy 9 points10 points  (0 children)

      You don't know him or her. They might have many reasons why they're being overly cautious.

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            [–][deleted] 24 points25 points  (1 child)

            Once it gets down to the same fatality rate as cars (35,000/year in the US) or the regular flu (56,000/year) I think you just have to bite the bullet and go with it. People need to get used to the idea that we're never going to get rid of it fully. Like Influenza, it will persist.

            ​

            Even if the vaccine is effective in 30% of the population, we'd be near there. So basically, once the older population is vaccinated, we should be good to go.

            ​

            If we get down to those numbers, and we still have to live like this, there will be a massive backlash. People are not going to want to live like this for something that is as dangerous as the seasonal flu (with a vaccine)

            [–]corporate_shill721 177 points178 points  (143 children)

            Spring 2021

            Compliance is already falling even without a vaccine. People aren’t going to sacrifice another round of proms/weddings/football/getting together with friends and family.

            [–][deleted] 62 points63 points  (23 children)

            I've bern saying this for a while. There's simply no way in hell that people will tolerate another year of no fun and events

            [–]corporate_shill721 55 points56 points  (21 children)

            And at some point it doesn’t become those people’s fault and it becomes the fault of never mounting an effective response.

            You can’t ask people to give up a year of their lives.

            [–]mattikus94 27 points28 points  (12 children)

            Why can't we ask people that? Rather give up a year of my life than potentially dying or causing others death, resulting in them losing the rest of their lives.

            One year is a small price to pay in comparison to the latter.

            [–]corporate_shill721 42 points43 points  (9 children)

            You try asking 365 million people to do that:) I wait for the response.

            [–]mattikus94 12 points13 points  (7 children)

            Of course they won't, but you're saying that we can't ask, when that is simply false. But yeah, people are done. Selfishness and lack of empathy for our species in combination of our governments response will just continue to kill more people.

            "It is what it is"

            [–]corporate_shill721 29 points30 points  (6 children)

            I think it’s clear from a global perspective that the only countries that are really succeeding here are countries that 1)locked down hard managed to eliminate it ie New Zealand and AU or 2) countries that instituted a MASSIVE test trace system (most Asian countries). The EU/US strategy of managing it through restrictions/social distancing/masks isn’t working. And probably inevitably, never really was going to work very well.

            [–]fastidiousavocado 14 points15 points  (1 child)

            Japan is managing through mask use. Masks are very important to success in Asian countries.

            [–][deleted] 4 points5 points  (0 children)

            Doesn't Japan actually do contact tracing? As opposed to US.

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              [–]NoGiNoProblem 1 point2 points  (0 children)

              365 million people

              7.5 billion. The world is bigger than America

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                    [–]PatsonicalBoosted! ✨💉✅ 86 points87 points  (39 children)

                    Spring is optimistic imo, I think it'll be closer to summer/early-autumn

                    [–]corporate_shill721 66 points67 points  (3 children)

                    Spring will be the a combination of a social ending meeting with vaccines. I’m sure it’ll lead to spikes, but hopefully they won’t be as big as the ones we are experiencing now

                    [–][deleted] 12 points13 points  (1 child)

                    Experiencing now, ftfy

                    [–]corporate_shill721 11 points12 points  (0 children)

                    Thank you!

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                      [–][deleted] 14 points15 points  (3 children)

                      Once older populations are vaccinated, the death rate will fall (HOPEFULLY) below the flu.

                      ​

                      We don't need everyone to be vaccinated to get to that point. 95% of the hospitalizations and deaths are from people 50 and over

                      [–][deleted] 59 points60 points  (28 children)

                      Summer/Fall 2021 is when the public health experts would end masks and distancing, if they had their way. But the public is going to end it themselves once the vaccine is out in the Spring, and I’m honestly going to be with them at that point.

                      If I’ve isolated for a year and I have the shot in my arm, what more can you expect from me? I’m moving on after that point, and I suspect 95% of people will too.

                      [–]MrPotatoFingers 28 points29 points  (18 children)

                      The question is whether you will have your shot at that point. How quickly can they vaccinate the entire population?

                      [–]PM_UR_FELINES 19 points20 points  (9 children)

                      The important people will be vaccinated first, the people we’re all concerned over (grandma, the immune compromised, etc).

                      If you’re worried about yourself, you can still isolate and take precautions.

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                        [–]anglophile20Boosted! ✨💉✅ 2 points3 points  (0 children)

                        i think they're still aiming to get the important people vaccinated before year end, regular people without extra risk maybe in spring

                        [–][deleted] 6 points7 points  (0 children)

                        There's going to be a lot of people that once a vaccine is approved will just figure that the health crisis is over and will go back to business as usual, even though they haven't personally been vaccinated.

                        [–]Not_as_witty_as_u 4 points5 points  (3 children)

                        Agree but I'll still probs wear a mask but let my guard down otherwise

                        [–]anglophile20Boosted! ✨💉✅ 5 points6 points  (0 children)

                        that's reasonable, it's been common in a lot of countries even before this to wear masks in high traffic places like airports

                        [–]ColonelBy 9 points10 points  (1 child)

                        While I can't expect everyone to keep wearing them as a matter of routine after all of this, I do hope the experience has at least normalized the idea of temporarily wearing one if you have a cold or something similar and still have to go out. We could really make a dent in future cold and flu seasons if people change their thinking about this somewhat.

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                            [–]DunkFaceKilla 19 points20 points  (26 children)

                            Once I get Vaccinated I see zero reason to follow the restrictions

                            [–]corporate_shill721 45 points46 points  (8 children)

                            I see more and more people saying that ON THIS REDDIT

                            So people are out of their mind if they think the average population will follow them

                            [–][deleted] 13 points14 points  (0 children)

                            You’re right, the average population is not following them currently.

                            [–]robots-dont-say-ye 4 points5 points  (6 children)

                            Sorry if I’m stupid but, why would you follow those precautions if you’re vaccinated?

                            [–]DeezNeezutsBoosted! ✨💉✅ 25 points26 points  (0 children)

                            Once I see community spread drop down to almost zero I will take mine off.

                            [–][deleted] 5 points6 points  (4 children)

                            Once I caught it and developed antibodies I’ve been wearing a mask in public and that’s it. Everything else I haven’t been doing.

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                              [–]gannerBoosted! ✨💉✅ 2 points3 points  (0 children)

                              What I keep saying every time one of these threads pops up is that "normal" isn't a switch we flip to from one state to another. It's gradual progress. Indoor concerts? Not happening in spring. Mask mandates, at least in most major cities? Not gone by spring. But the way many people are living their lives? The amount of personal social interactions, the fraction of people eating in restaurants? Those things will be increasing. Outdoor concerts and events? Probably happening late spring/summer next year. Full on thousands of people music festivals where people travel from around the country to congregate? Probably not happening before fall.

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                                [–][deleted] 51 points52 points  (16 children)

                                People will tough it out for the winter but that’ll be it. Next March will be a year since “two weeks to flatten the curve” and people will not be willing to sacrifice another spring/summer.

                                [–]mmmegan6 14 points15 points  (13 children)

                                Some of us will (the ones who are determined to make it out of this without getting covid)

                                [–]Westcoastchi 41 points42 points  (0 children)

                                You may be waiting forever.

                                [–]theshindy 33 points34 points  (3 children)

                                If you want to stay in and live in fear even after getting your vaccine shot and there being other solutions widely available, that’s your own prerogative. But don’t push for or demand blanket restrictions from the government for everyone else when we want to live the life we once had again.

                                [–]hectorse2011 13 points14 points  (3 children)

                                At that point that will be like refusing to live without ever getting the flu. The virus will continue to mutate and become more virulent but less deadly.

                                At that point that's your call, but the question would be "why?"

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                                    [–]mr_quincy27 54 points55 points  (42 children)

                                    I think by Spring/Summer 2021 maybe...

                                    [–]xansllcureya 58 points59 points  (7 children)

                                    Yeah, wouldn’t summer be nice as people are gradually getting vaccinated? Maybe we could even have a tracker for that, or there’s like a new category on Worldometer for prevented infections so we can view the progress.

                                    [–]macnbloo 61 points62 points  (0 children)

                                    Like the blue cured metric in plague inc

                                    [–]mojo276 21 points22 points  (1 child)

                                    You'll see it because all of the numbers would drop (numbers, hospitalizations, deaths, etc.).

                                    [–]xansllcureya 12 points13 points  (0 children)

                                    Yeah that’s true eventually, but at first for some more instant gratification.

                                    [–]Turniphead92 9 points10 points  (3 children)

                                    It will be a summer of decadence.. people are going to go wild!

                                    [–]Necropolis750 2 points3 points  (0 children)

                                    Then it'll truly be the new Roaring Twenties.

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                                      [–]BlazingSaint 6 points7 points  (0 children)

                                      I'd say Spring. It'd be a whole year by then.

                                      [–]Tekki777 4 points5 points  (0 children)

                                      Something tells me by next the two years instead, especially in America

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                                        [–]Wild_Hunt 5 points6 points  (0 children)

                                        Realistically how long will compliance last? Christmas and New Year will be the real test.

                                        [–]tqbBoosted! ✨💉✅ 3 points4 points  (0 children)

                                        I think they’ll gradually go away over a year or so once a vaccine comes out

                                        [–]DrDerpberg 3 points4 points  (0 children)

                                        It will probably be gradual, but I think we can expect deaths and hospitalizations to get better much more quickly as health care workers and vulnerable people get vaccinated first.

                                        It all boils down to the effective R0 - it was ~5.7 in the early days of the pandemic before any social distancing, meaning you need ~80% immunity to go back to that kind of lifestyle without cases going up. But masks and distancing change that drastically, and as immunity creeps up you'll start to see more and more "normal" without a corresponding increase.

                                        [–]Sn1peBoosted! ✨💉✅ 36 points37 points  (19 children)

                                        I feel this will honestly depend on who wins in about a week. If Trump’s still in office, the whole distribution of the vaccine will probably be a shit show but will eventually get done months and months down the road, but if Biden wins everything will possibly go smoothly and may come out sooner since there will probably be a plan in place.

                                        If the distribution goes well, the quicker we can rip off those masks and go back to normal, but if there are any hiccups or any issues like we’ve had with testing, PPE, stay-at-home orders (issued way later than they should have), it’s going to be a long ride.

                                        [–]ChicagoComedianI'm fully vaccinated! 💉💪🩹 29 points30 points  (4 children)

                                        Despite what they say the President has a minimal role in “distributing” the vaccine.

                                        [–]corporate_shill721 18 points19 points  (2 children)

                                        Even WITH Trump, I actually think distributing the vaccine will to pretty smoothly, because it’s basically on autopilot.

                                        Now Trump May say some BS that will discredit the vaccines or we may see some of the same petty bullshit we saw with PPE and ventilators, but I mean, the President is pretty minimal in the whole vaccine thing

                                        [–]captainslowww 9 points10 points  (0 children)

                                        If he's still in office by then, he will absolutely do the same profiteering shit they did with the PPE. There is no doubt of that in my mind whatsoever. Like, it's not even a question.

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                                          [–]TheRatKingXIV 7 points8 points  (0 children)

                                          Yeah, but every problem we've been running into with this crisis is centered around "No Centralized, Effective Federal Plan." Instead, we have 50 scatological responses of varying success all crippled by lacking the resources and ability to take on debt as a federal government can. Not to mention that the aforementioned federal government has been actively fighting any mitigation efforts. To put it mildly, they can, and almost certainly will, fuck this up if given the chance.

                                          [–]dvoecks 30 points31 points  (9 children)

                                          I'm a little pessimistic about how smoothly anything can be transitioned. The Trump team was completely disinterested in transitioning in smoothly. I can't imagine how few shits they're going to give on their way out the door.

                                          [–]FockerCRNA 22 points23 points  (3 children)

                                          Biden et al surely know this and will essentially clean house with the exception of career trustworthy fed employees. The smoothest transition might just be to start with a clean slate, or mirror what they had in place just 4 years ago. I'm obviously ignorant of the inner workings of government at that level, but from my layperson perspective, that would make sense.

                                          [–]likeahurricane 17 points18 points  (2 children)

                                          There is a whole army of political agency leadership that is only 3.5 years out of experience, and they actually take governance very seriously. If Biden wins, I suspect there will be 1) a national response strategy (finally!), 2) a vaccine rollout strategy, and 3) a stimulus/coronavirus response bill ready to go by January in agencies and Congress respectively.

                                          [–]tomoldbury 8 points9 points  (0 children)

                                          The one thing that could stall Biden's response here is if they don't get a Senate majority. If Mitch still pulls the strings, who knows?

                                          538 puts them at about an 80% chance which is good odds, but still very realistically a Biden pres + Repub. senate, which will be a difficult situation for any COVID response.

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                                                [–][deleted] 2 points3 points  (0 children)

                                                As soon as hospitals are consistently below capacity, which could theoretically happen without a vaccine too via herd immunity.

                                                [–]gilman3 7 points8 points  (1 child)

                                                During the last American presidential debate, it was mentioned that '21 would be masks and distancing with a '22 sunset. However, that was also before this news. So here's to hoping.

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                                                  [–]BenzamineFranklin 346 points347 points  (40 children)

                                                  Good news! Has the data review process begun for this vaccine?

                                                  [–]MR-DEDPUL 233 points234 points  (6 children)

                                                  Under rolling review in the EU, alongside Pfizer.

                                                  Phase III data is expected sometime next month.

                                                  [–]RannashaBoosted! ✨💉✅ 128 points129 points  (0 children)

                                                  Under rolling review in the EU

                                                  Also Canada.

                                                  [–]BenzamineFranklin 17 points18 points  (0 children)

                                                  Nice.

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                                                    [–]DaveInLondon89 35 points36 points  (32 children)

                                                    followup; could the vaccine go into production while the data review is taking place?

                                                    [–]anillop 123 points124 points  (1 child)

                                                    Yes they are taking the risk (backed by govt money) and producing doses on spec of being approved that way they can cut out a lot of time between approval and distribution.

                                                    [–]RonaldoNazario 45 points46 points  (0 children)

                                                    Already is.

                                                    [–]canseco-fart-box 66 points67 points  (22 children)

                                                    It already is and has been since April. The US ordered 300 million doses to be delivered by EOY

                                                    [–]stillusesAOL 32 points33 points  (19 children)

                                                    First people to receive it? Everyone who’s been wearing masks in public to the front of the line! That isn’t the most effective way to do it, ironically.

                                                    [–]petarisawesomeo 51 points52 points  (14 children)

                                                    Frontline medical workers and the elderly will probably be first in line

                                                    [–]danfoofoo 47 points48 points  (9 children)

                                                    You misspelled "rich people"

                                                    [–][deleted] 42 points43 points  (4 children)

                                                    Not really, medical staff will be first. It all goes to shit without them. Rich will of course get it too one way or another, but docs and nurses will be the first in line out of the general public.

                                                    [–][deleted] 14 points15 points  (2 children)

                                                    And they absolutely deserve it. It’s insane how many healthcare workers we’ve lost to Covid. And it’s incredible that they continue to treat people when one, their lives are on the line, and two, a lot of the people they are helping have most likely been ignorant to safety guideline concerning the virus.

                                                    [–]you_me_fivedollars 2 points3 points  (0 children)

                                                    As a healthcare worker with a crappy immune system, I would feel so much better working after getting this shot!

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                                                        [–]Vricrolatious 2 points3 points  (0 children)

                                                        Right?!

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                                                          [–]stillusesAOL 4 points5 points  (0 children)

                                                          Fer Sher. And people with connections to private doctors. You know, “connections”.

                                                          [–]Pentt4 5 points6 points  (2 children)

                                                          Medical workers and Military first. Now the second group is def the more interesting question. You go two different routes. The most productive per dosage which would be towards the far more mobile youth who are far more likely for spreading or you give it to the most at risk which are the elderly. The issue with the at risk is that its for the least mobile so itll be for the least impactful for minimizing spread.

                                                          [–]stillusesAOL 1 point2 points  (0 children)

                                                          That is interesting, giving it to the people who are most likely to spread it, most likely to have complications from it… How about a well-reasoned proportion of both!

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                                                                [–][deleted] 6 points7 points  (0 children)

                                                                I think so

                                                                [–]burkey347 6 points7 points  (4 children)

                                                                Is the vaccine already in production tough?

                                                                [–]hammer-2-6 31 points32 points  (0 children)

                                                                Yes. India is producing a few million doses of the Oxford candidate with expectation of ramping up as soon as supporting data/ required clearance is obtained.

                                                                [–]ifly4funn 1 point2 points  (0 children)

                                                                Affirm. They have contracts with several manufacturers all over the world, including in Russia and China.

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                                                                  [–]Grilledcheesedr 282 points283 points  (63 children)

                                                                  The end has been approaching at a painfully slow speed but at least the end is finally in sight.

                                                                  This is wonderful news.

                                                                  [–]desenagrator_2 135 points136 points  (1 child)

                                                                  I have to remind myself that each day passing is one day closer to the end of this mess.

                                                                  [–]LevyMevy 9 points10 points  (0 children)

                                                                  There's gonna be a random weekend in 2023 when you'll be traveling to Europe and I'll be arguing with the sales lady at Sephora and some other guy will be freely strolling a bookstore, and the COVID restrictions will randomly pop into our heads and we'll be like "damn that was a nightmare, thank god it's over" and continue on with our lives.

                                                                  [–]bobbyOsullivan 54 points55 points  (0 children)

                                                                  Considering how long stuff like this usually takes it’s happening at a lightning fast pace. But I feel ya my friend.

                                                                  [–]VegetableSupport3 29 points30 points  (0 children)

                                                                  Think about the relief when we know it works, even if we can’t get it for 6-months.

                                                                  The fact that we know it’s out, and being distributed will relieve a ton of anxiety and almost certainly boost the economy.

                                                                  [–]pujpujaa 10 points11 points  (0 children)

                                                                  The end was in sight to begin with but the finish line kept moving

                                                                  [–][deleted] 38 points39 points  (3 children)

                                                                  Now you get to see the people who are really enjoying the apocalypse porn from r/collapse showing their true colors.

                                                                  "Sure it might start to be distributed in a month, but we'll be living with this for a looooooong time". They don't want the ride to end.

                                                                  [–]cologne1 4 points5 points  (0 children)

                                                                  Yes. We only have about another 9-12 months before enough people are vaccinated assuming the safety data holds up.

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                                                                    [–]Helloskellington 158 points159 points  (79 children)

                                                                    The article says the vaccine would provide protection for about 1 year. Assuming everyone in the world could get it quickly enough (impossible I know) does that mean the virus would effectively go extinct?

                                                                    [–]MagnesusBoosted! ✨💉✅ 304 points305 points  (41 children)

                                                                    Doubt it will be achieved - we've managed to eradicate o ly smallpox and mostly polio, the rest is still with us despite the vaccines. Antivaxxers will make sure such eridactions will never be repeated.

                                                                    We'll just get a covid shot every year from now on. Maybe combined with flu vaccine.

                                                                    [–]featsofstrength81 47 points48 points  (1 child)

                                                                    Are they still leaning towards the vaccines needing a booster 3 months later? Or is a full year looking more likely?

                                                                    [–][deleted] 46 points47 points  (0 children)

                                                                    Initial jab then second jab 28 days later is what most of the front runners have.

                                                                    We don't know how long the immunity will last given how short the trials are so far , it's being constantly monitored though so if we start seeing lots of those with the vaccine getting infected after 6 months then that would tell us for example it only lasts about 6 months. I think the expectation is that it's likely to be a year +

                                                                    [–]gilman3 6 points7 points  (3 children)

                                                                    Yea they hybrid a lot of vaccines these days; I can see it pairing with flu. Cant wait to hear what they call it. CoFlu, Fluvid. Im on the edge of my seat here.

                                                                    [–]MediumPlace[🍰] 4 points5 points  (0 children)

                                                                    Flu-rona

                                                                    [–]adlerhn 1 point2 points  (0 children)

                                                                    I'm sure they'll find a catchy name like SARS-CoV-2-INFL-2021

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                                                                      [–]CMcCord25 5 points6 points  (0 children)

                                                                      Plus you got crazy people who think that they will also inject a microchip in you while getting the vaccine

                                                                      [–]sickntwisted 19 points20 points  (17 children)

                                                                      even if we ignore anti-vaxxers, can the toughness of this virus also be taken into account? by this I mean the way it survives for a long period of time in surfaces and the transmission to household pets.

                                                                      I have no clue if this is something normal in other viruses.

                                                                      edit: ffs, I am only asking a question...

                                                                      [–]SwoleYaotl 64 points65 points  (11 children)

                                                                      We should never ignore antivaxxers. They're a serious threat to our collective health.

                                                                      What exactly are you asking? I'm unclear of what your question is.

                                                                      [–]audirtBoosted! ✨💉✅ 35 points36 points  (5 children)

                                                                      They're pointing out that Covid is somewhat robust, as it can live outside a host for a prolonged period of time. They're asking if that characteristic of Covid will impact a vaccine's effectiveness?

                                                                      NOTE: I have no idea what the answer is, I'm just restating the question.

                                                                      [–]sickntwisted 34 points35 points  (4 children)

                                                                      thank you.

                                                                      and in reply to the other commenter, I'm not ignoring anti-vaxxers in general. I'm ignoring them in the context of my question. even if anti-vaxxers didn't exist, would the virus be a permanent fixture in our life due to its robustness?

                                                                      [–]TvistedBoosted! ✨💉✅ 6 points7 points  (1 child)

                                                                      I don't think its ability to live on surfaces or infect pets has much to do with its spread.

                                                                      We'll probably be living with it for a while because it's really contagious among people who gather closely and talk/sing, particularly indoors without masks; that much seems established, and a lot of human activities are like that (sporting events, parties, bars, restaurants, churches, schools, workplaces etc.)

                                                                      But we've only been living with it for about a year. It's a novel virus. Nobody really knows how this will play out, because there's no way to know.

                                                                      I'll get the first Oxford jab I can get my hands on but I expect I'll have to get it every year, maybe more than that.

                                                                      [–]sickntwisted 2 points3 points  (0 children)

                                                                      yeah, I understand there's no way to know. my question was more a "what do you think?" it's nice to discuss these here and see if people's opinions/hopes align with mine.

                                                                      I'm very optimistic in regards to this vaccine. I'm in the UK and I can't wait to be able to receive it. my family is abroad and I haven't been able to be with them since last year... the day I will be able to not feel guilty over the potential spread of this virus is the day I will finally be with them. for now, I don't mind being overtly cautious and do my part.

                                                                      edit: words.

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                                                                        [–]HippGris 9 points10 points  (3 children)

                                                                        I mean they're not wrong, even if everyone gets vaccinated and there is no human contamination for a whole year, since the virus can apparently be passed on to different animals, then there's a possibility that it will keep reappearing once humans' vaccine-induced immunity decreases.

                                                                        [–]timetravelhunter 1 point2 points  (0 children)

                                                                        Antivaxxers are not a threat to ending COVID. The millions of people in the world that won't be able to get this even if they wanted to are.

                                                                        [–][deleted] 6 points7 points  (4 children)

                                                                        They are still trying to figure it out, but the general consensus is that in normal conditions the virus does not survive on surfaces in enough quantity to infect.

                                                                        Obviously, this is still being researched so we might be completely wrong.

                                                                        As for the pets one, it seems to be incredibly rare.

                                                                        [–]duffman7050 4 points5 points  (1 child)

                                                                        People's hesitancy or refusal of this vaccine aren't for reasons typical of antivaxxor logic.

                                                                        Most people I've asked DO want to get the vaccine but want to wait to see how others respond. I don't fault them for this seeing as how the potential financial and political gain is extraordinary, perhaps enough to trump safety concerns.

                                                                        Also, millions of people have been working throughout this entire pandemic and haven't fallen ill. Asking them to now take a warp speed vaccine for something that hasn't affected them is just another risk to incur.

                                                                        [–]Werty071345 1 point2 points  (1 child)

                                                                        what about sars and mers?

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                                                                          [–]RandomChurn 46 points47 points  (2 children)

                                                                          No virus with an animal reservoir can go extinct. We were able to eradicate smallpox only because it has no animal reservoir.

                                                                          [–]leaklikeasiv 11 points12 points  (1 child)

                                                                          Destroy all pangolins? /s

                                                                          [–]IanT86 9 points10 points  (4 children)

                                                                          Where does it say it would only be for 1 year?

                                                                          [–]corporate_shill721 9 points10 points  (0 children)

                                                                          I think people need to settle on the fact that the virus will never go extinct. It would be nice if it would but like you said it’s impossible+of course some people will just have the unluck of the draw and not be helped by the vaccine.

                                                                          But a vaccine would bring it down to simmering levels and allow everyone to return to normal.

                                                                          [–]birdsofterrordiseI'm fully vaccinated! 💉💪🩹 7 points8 points  (5 children)

                                                                          It may not go extinct- we don’t know how long the effect is induced for (this may be a twice or yearly shot at minimum) Nor have we figured out exactly where the virus came from. It could have a mutation or new strain we need to develop new vaccines against like the flu. We still haven’t eradicated polio unfortunately for example.

                                                                          [–]Werty071345 26 points27 points  (4 children)

                                                                          The only reason polio is still around is because of the geopolitics of the regions that it still resides in, not because there's anything wrong with the vaccine.

                                                                          [–]PartyOperator 2 points3 points  (0 children)

                                                                          There is something wrong with the most common vaccine - it’s a live attenuated vaccine taken orally that is excreted in faeces and can lose some of its attenuating characteristics. The live vaccine is great for getting most of the way to eradication but makes it quite hard to finish the job. Inactivated, injected vaccines exist but are more expensive and harder to administer.

                                                                          http://polioeradication.org/polio-today/polio-prevention/the-virus/vaccine-derived-polio-viruses/

                                                                          [–]birdsofterrordiseI'm fully vaccinated! 💉💪🩹 3 points4 points  (0 children)

                                                                          Yeah, but politics affect vaccination and that is precisely my point. If more people didn’t get the polio vaccine here, we probably would have polio outbreaks here. This is one of the huge worries with the Covid vaccine.

                                                                          [–]DarthYippee 4 points5 points  (0 children)

                                                                          And because the CIA planted agents posing as vaccination workers in their search for Osama bin Laden.

                                                                          https://www.scientificamerican.com/article/how-cia-fake-vaccination-campaign-endangers-us-all/

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                                                                            [–]zonadedesconfortoBoosted! ✨💉✅ 2 points3 points  (0 children)

                                                                            It wouldn't. Most likely it will evolve to become less lethal or less contagious. This virus however does not mutate as fast as the flu, unless something it goes through major structural changes, immunity should last a lot longer than 1 year

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                                                                              [–][deleted] 61 points62 points  (16 children)

                                                                              Just give me the vaccine already!

                                                                              On a a serious note, do you think we can get it at the start of 2021?

                                                                              [–]muncash 73 points74 points  (14 children)

                                                                              I don't think so. Medical staff and at-risk population have priority. Myself, as an 25 years old healthy person, can't see me getting the vaccine until 2021 Q3/Q4.

                                                                              [–][deleted] 43 points44 points  (4 children)

                                                                              Nope. Q 2.

                                                                              [–]muncash 19 points20 points  (2 children)

                                                                              Living in Argentina? Na, I'm being optimistic about Q2 for health personnel and Q3 for the rest.

                                                                              [–][deleted] 1 point2 points  (1 child)

                                                                              How intrusive would you say are the restrictions?

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                                                                                [–]gooner712004 12 points13 points  (1 child)

                                                                                We don't need to vaccinate every person to achieve herd immunity, they're not aiming for that.

                                                                                [–]muncash 1 point2 points  (0 children)

                                                                                I know, I'm just answering his question. I wouldn't take the vaccine if that means taking it away from a risk patient or frontline workers.

                                                                                [–]ZoonToBeHero 4 points5 points  (0 children)

                                                                                There are a lot of medical staff and at risk population in this world, so as they start to get vaccinated, it is already starting to help society.

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                                                                                    [–]kc44135I'm fully vaccinated! 💉💪🩹 39 points40 points  (16 children)

                                                                                    So in layman's terms, this means it works, right? It can fight off Covid? So, we're just waiting to see if it safe at this point?

                                                                                    [–]CrystalMentholBoosted! ✨💉✅ 67 points68 points  (12 children)

                                                                                    The real test is the phase iii trials going on now, where they inject half the people with a placebo, and half with the real vaccine, to see if the people that receive the vaccine get sick less often than the people that receive the control.

                                                                                    Biology is weird - just because they can see immune responses generated by the vaccine is not a guarantee that it will help you fight off the disease. However, it does make it seem much more likely that it will work for that purpose. That's why they run the big trials, to make really sure that it works before dosing the world.

                                                                                    [–][deleted] 24 points25 points  (10 children)

                                                                                    It’s also something of an open secret that the phase III trials have going swimmingly. Hence the rolling review, so the actual approval involves examining a spreadsheet that’s basically like one they’ve already seen, only with enough rows in it to pass a high statistical threshold. When the marketing approval is formally sought I imagine it’ll be turned around within a week, maybe even 24h

                                                                                    [–]69_fan 14 points15 points  (0 children)

                                                                                    The rolling review only looks at the results of prior phase 1 and 2 trials. Phase 3 trial is still blinded and therefore not part of this review yet.

                                                                                    [–]LevyMevy 2 points3 points  (0 children)

                                                                                    It’s also something of an open secret that the phase III trials have going swimmingly.

                                                                                    I wish more people understood this! The fact that more and more world governments are placing orders for the vaccine & the trials are expanding is AMAZING news. They're not just taking a stab at the dark with where they throw their money, multiple first world governments are pouring over Oxford's (and Moderna's and Pfizer's) data and really like what they're seeing.

                                                                                    [–]Nikiaf 5 points6 points  (1 child)

                                                                                    The fact of the matter is that we're dealing with a virus that's been known and studied for a very long time and without trying to make light of things, it's not a particularly dangerous virus. At least not on the level of an HIV or smallpox. What the researchers have been tasked with is something in the same general concept as a flu vaccine, just to protect against a different virus. There was really no reason to ever doubt they could find one that works, it'll really just come down to how long immunity lasts. Since coronaviruses don't mutate rapidly like influenza does, we can still hope for something in the 1+ year range.

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                                                                                      [–]Drunk_Lahey 1 point2 points  (0 children)

                                                                                      I think it's important to remember too that it's not just looking at people with the vaccine not getting infected at all, but also getting less sick if they do still catch it. I believe flu vaccines work the same way. There's a chance you could still get it but it will be way milder than if you didn't, which obviously for COVID would make a huge difference as well.

                                                                                      [–]Carlin47 4 points5 points  (0 children)

                                                                                      I think this is the problem with a lot of current scientific information. Many things in science are complicated and have clauses, you can't always break them down into laymens terms. I think the world needs to be a better job at ensuring rhat evrry citizen has a fundamental knowledge about basic biology and chemistry at least, since those fields literally govern our physical existence

                                                                                      PS. Physics isnimportnt too but not for the everyday like bio and chem are

                                                                                      [–][deleted] 8 points9 points  (0 children)

                                                                                      No, we won’t have a clue about how effective it is against Covid until the phase III is completed. And we won’t really know much about it until a few years from now after we’ve done a real phase III in the form of distributing the vaccine broadly.

                                                                                      [–]vectorian 1 point2 points  (0 children)

                                                                                      No. This finding just shows that the immune system reacts to the vaccine, and that it looks similar to the reaction to the real virus.

                                                                                      If it provides immunity is still unknown. Unfortunately. But it will be soon, when Phase III trial results come in.

                                                                                      [–]hotshot117 34 points35 points  (3 children)

                                                                                      We're in the endgame now

                                                                                      [–][deleted] 23 points24 points  (1 child)

                                                                                      Let's kill it properly this time.

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                                                                                        [–]Phyr8642 33 points34 points  (20 children)

                                                                                        Has there been any news about potential side effects yet? I'm not really worried myself, its just that if it does have side effects lots of people will not take it.

                                                                                        [–]RannashaBoosted! ✨💉✅ 99 points100 points  (7 children)

                                                                                        Results that have been made public so far have shown the usual vaccination-related side effects: soreness at the injection site, fatigue, low fever. All short term.

                                                                                        [–]Phyr8642 12 points13 points  (0 children)

                                                                                        Thank you for the information.

                                                                                        [–]Nikiaf 2 points3 points  (0 children)

                                                                                        Important to keep that all in mind. I've seen articles from established news outlets calling what you've listed as severe side effects; but having a low-grade fever for 24 hours is the furthest thing from "severe".

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                                                                                          [–]wallflower7522 37 points38 points  (6 children)

                                                                                          I’m in the Pfizer trial and my initial side effects were unpleasant but not severe. I have to follow up for two more years to monitor long term side effects.

                                                                                          [–]horrificabortion 23 points24 points  (0 children)

                                                                                          Thank you for being a part of the process 👍

                                                                                          [–]TheDrunkSemaphore 1 point2 points  (2 children)

                                                                                          Just curious, how'd you get into the trial and are you getting paid anything outside of travel reimbursements?

                                                                                          [–]wallflower7522 2 points3 points  (0 children)

                                                                                          Found an article about it on a local news site. The compensation is $120 a visit, 3 initial visits and 3 long term visits, and $5 a week to fill out a symptom tracker.

                                                                                          [–]bikebuyer 1 point2 points  (0 children)

                                                                                          There was a lot of publicity and links including on this sub to locate trials in your area. Once you sign up they contact you and they determine your eligibility based on your health history. I’m in Oxford and get $100 per visit and more if I get sick because it requires more appointments. Also, you can drop out at any point (the two years is not required as stated above). For example, if a vaccine is released, you can get the vaccine but will no longer be eligible for the study.

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                                                                                              [–]BobbyKristina 23 points24 points  (0 children)

                                                                                              Mall Santas across the USA cheering in unison!

                                                                                              [–]Werty071345 15 points16 points  (2 children)

                                                                                              When will they be done reviewing?

                                                                                              [–][deleted] 12 points13 points  (0 children)

                                                                                              early December I think

                                                                                              [–][deleted] 8 points9 points  (0 children)

                                                                                              I read pfizer was supposed to be early November, for what its worth.

                                                                                              [–]Trumpdefmolestedkids 9 points10 points  (6 children)

                                                                                              Is this an easily manufactured vaccine? And is it scalable? Not that I'm an expert but this one seemed the most hopeful from the beginning simply because it was a mature delivery system.

                                                                                              Tangentially, will this be available in the US or is there a vaccine using the same/similar technology being developed in the US?

                                                                                              Last question - have their been any instances of ADE on this vaccine?

                                                                                              [–][deleted] 17 points18 points  (3 children)

                                                                                              ' Is this an easily manufactured vaccine? And is it scalable? '

                                                                                              Reasonably, there likely won't be capacity for this vaccine to do the whole world but 1-2 billion doses over the next 6-9 months is acheivable, it will work in tandem with the other vaccines.

                                                                                              ' Tangentially, will this be available in the US or is there a vaccine using the same/similar technology being developed in the US?'

                                                                                              It will but probably later than it is in europe and elsewhere as the FDA seems to be slow (took them 7 weeks to restart the US trial compared to a week for elsewhere) and have more requirements than europe ect.

                                                                                              ' Last question - have their been any instances of ADE on this vaccine? '

                                                                                              No, all the vaccines have had a decent amount of research for this because obviously they do not want this.

                                                                                              [–]ConspiracyHorn 1 point2 points  (1 child)

                                                                                              took them 7 weeks to restart the US trial compared to a week for elsewhere

                                                                                              Can they not use data collected internationally to pass trials in other countries? I thought they had to do these phase III trials in Brazil because there was enough of an outbreak there to prove efficacy. Unless I misunderstand and it's a separate process that it took 7 weeks to restart.

                                                                                              [–][deleted] 1 point2 points  (0 children)

                                                                                              Basically the FDA requires those seeking approval to put it all in the format they like and there's an element of beaurocracy (the 7 weeks was mainly down to this).

                                                                                              The European and British bodies have moved themselves and are flexible on the format of the data provided the scientists who run it are happy.

                                                                                              That's the difference.

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                                                                                                [–]ifly4funn 2 points3 points  (1 child)

                                                                                                MRNA vaccines (Pfizer, Moderna) are extremely easy to mass-produce and very scalable. These adenovirus-vector ones from J&J and Oxford/AstraZeneca are harder to mass-produce.

                                                                                                [–]ifly4funn 13 points14 points  (1 child)

                                                                                                I have so much respect for these researchers and scientists working on these fantastic vaccines. True saviors. Everyone, from the data scientists to the biochem researchers to the immunologists and independent council boards are saving thousands of lives for each hour they put in to the work. This is how we as humans must survive. Through innovation. That’s the only reason we’ve come this far, and it’s the way to build a better future for our children.

                                                                                                [–]ModricTHFC 18 points19 points  (13 children)

                                                                                                Why does this particular vaccine trial (there are hundreds) always get lots of media attention?

                                                                                                [–]PFC1224[S] 72 points73 points  (8 children)

                                                                                                It's the furthest ahead

                                                                                                [–]iReddt 15 points16 points  (7 children)

                                                                                                Pfizer/BioNTech vaccine is pretty far along also. I’m in the trial and everyone in the follow up appointments seem really excited about the results that are coming in.

                                                                                                [–][deleted] 20 points21 points  (1 child)

                                                                                                It was the first one because the researchers were coincidentally already working on a coronavirus vaccine when the pandemic broke out. They just swapped in this one and hit the gas.

                                                                                                [–]rocketwidgetBoosted! ✨💉✅ 9 points10 points  (0 children)

                                                                                                There are 179 candidates, but "only" 56 in human trials and "only" 15 in Stage III (still vastly more than any other vaccine for anything ever)

                                                                                                https://biorender.com/covid-vaccine-tracker

                                                                                                Of those 15, only a couple are viewed as the "best shot" of being first to be approved in the US, the Oxford (AZD1222) is one of them.

                                                                                                [–]GhostRiders 4 points5 points  (0 children)

                                                                                                Simply down to how far ahead they are.

                                                                                                [–]krazykris93Boosted! ✨💉✅ 6 points7 points  (1 child)

                                                                                                I wonder if there will be vaccine only events (you must have a record of getting the covid vaccine) after the vaccine is approved?

                                                                                                [–]Argos_the_DogBoosted! ✨💉✅ 1 point2 points  (0 children)

                                                                                                Get a WHO yellow card from Médecins Sans Frontières and get it dated and initialed when you get the COVID shot. Will help with the travel into and out of other countries at least. I do fieldwork in a developing country and it's handy to have around at the airport coming in.

                                                                                                [–]NutinButAPeanut 3 points4 points  (0 children)

                                                                                                If only the FDA didn't delay this by a month reviewing one unexplained illness while other countries swiftly moved forward...

                                                                                                [–][deleted] 1 point2 points  (0 children)

                                                                                                I wonder how the world would be like if this vaccine is proven to be effective and can be rolled out to the masses.

                                                                                                [–]googllgoog 4 points5 points  (17 children)

                                                                                                i hear some people who really dont want the vaccine into their body, even tough they are arent antivaxxers. Tbh , im also not so sure, i try to wait and see what gives

                                                                                                [–]dvoecks 26 points27 points  (6 children)

                                                                                                I look at it like this: I've never thought for a minute that it was a matter of if I get COVID. Without a vaccine, it's a matter of when. There are all kinds of reports of the virus causing weird, lasting side effects, even when it doesn't kill people. I'm willing to bet that a vaccine given to tens of thousands of people who were closely monitored is significantly less risky than the virus itself.

                                                                                                People worry about it being "rushed", but the research has basically been ongoing for decades into how to make these vaccines, because of SARS and MERS.

                                                                                                I'm taking it as soon as it's offered to me. It's not as if other vaccines have absolutely zero risk. I don't even think about that. I don't know why I'd start now.

                                                                                                [–]team_xbladz 8 points9 points  (0 children)

                                                                                                I look at it like this: I've never thought for a minute that it was a matter of if I get COVID. Without a vaccine, it's a matter of when.

                                                                                                I'm taking it as soon as it's offered to me. It's not as if other vaccines have absolutely zero risk. I don't even think about that. I don't know why I'd start now.

                                                                                                Thank you for this perspective. The reframing is helpful to me.

                                                                                                [–][deleted] 11 points12 points  (1 child)

                                                                                                It's also being "rushed" because we're not waiting for each step to get the all clear before the money is released for the next step like it normally would. Money is essentially a non-factor with these vaccines. That speeds things up considerably.

                                                                                                [–]The_Bravinator 1 point2 points  (0 children)

                                                                                                Also, if phase III is a matter of waiting for a certain percentage of trial subjects to get infected, that's going to be A LOT faster with a disease that's causing about a million recorded cases every three days worldwide (or every two days now? Looks like we're approaching about a half million recorded cases a day).

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                                                                                                  [–]VeganBigMac 11 points12 points  (2 children)

                                                                                                  I'm kind of sick of the phrase "I'm not an antivaxxer but....". I'm sorry, but at this point, if you are refusing to take it do to some incredibly small risk of side effect versus the actually known and real chance of death from the virus, you are no more than an antivaxxer.

                                                                                                  I hate it most from people in the medical field. No, your understanding of the risks of rushed vaccine trials does not outweigh your bastardization of risk assessment regarding the virus.

                                                                                                  [–][deleted] 0 points1 point  (1 child)

                                                                                                  Fuck it. I’m gonna die if I get the vaccine. I’m gonna die if I don’t get it. I’m gonna die if I get coronavirus, maybe that won’t kill me, but something else will. The COVID vaccine can’t be nearly as dangerous as driving with all the lunatics on I95 in MA, so fuck it, put it into my body.

                                                                                                  We’re all just sacks of meat who got here by accident waiting for something to come along and fucking murk us.

                                                                                                  I guess a slightly more intelligent take isn that yeah, it’s hard not to be a little anxious about this. Just gotta read all the science and data and see for yourself if it seems safe.

                                                                                                  I can tell you I wouldn’t be getting one of those Russian COVID vaccines.

                                                                                                  But good chance I get one of the US approved ones.

                                                                                                  [–]googllgoog 1 point2 points  (0 children)

                                                                                                  goddamn right

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