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[–]omibus 48 points49 points  (12 children)

I’m a software architect leading 20 developers, and I’ve been in brain fog and migraine La La Land for 6 months now. Luckily I work from home or I wouldn’t be able to work at all (can’t drive, and can’t walk more than 1/2 mile)

Propranolol is the only thing so far that has helped me, but I haven’t tried novavax yet.

[–]yoda13041yr 25 points26 points  (9 children)

I'm also a SWE, the Novavax booster significantly reduced my brain fog a month and a half ago. It's been one of the biggest impacts, and I've tried an enormous number of treatments and procedures at this point.

[–]shimmeringmoss 5 points6 points  (2 children)

SWE with brain fog here too… was already considering Novavax, really interesting to read this. Mine had cleared up, but I believe I probably had an asymptomatic reinfection recently. Which means I have to wait to get boosted :/

[–]thoughtsinslowmotion 1 point2 points  (1 child)

I’m in the Netherlands and it’s available for us now.

this year in June for one heavenly month I could think again. The fog came back tho :( and I’m still not sure what caused the lift as I was doing a heap of supplements at the time

I had covid April 19th again; and I have been wondering if that was it as it was the only thing that changed and if novavax is worth the risk. I got severe after cormirnaty tho (pericarditis flare up and new symptoms) and was down and out for 4 months after and never got back to pre vax; so I’m very hesitant.

Your post says it “had cleared” up, meaning it came back again too?

I can’t function at all; with the fog I’m doing stuff like forgetting I’m cooking and thus burning things like rice, twice ! in a row stuff and like that. 😭

creative ideas ? Nope. It’s like being in a swamp up there.

On good days I can read (reading David copperfield now) but those days aren’t as frequent as I’d like so it goes very slow. :( I’m out of work because of it.

[–]shimmeringmoss 3 points4 points  (0 children)

Sorry, yes, I didn’t phrase that very clearly. My initial brain fog eventually cleared, but now it’s returned again and I believe it’s due to an asymptomatic infection from when it was going around the office a few weeks ago. It’s really hard to function like this at work—like you, it also affects my memory. It’s like suddenly mentally aging four decades, or having a stroke. I was telling my sister about this and she asked if I told my manager and I was like fuck no, why would I give them a reason to closely watch me, or to let me go? Just struggle as best I can until it goes away and hope no one notices.

I’m taking a ridiculous amount of supplements too, although I know what made a difference for me personally and it wasn’t the supplements at all, but rather aspirin and nicotine patches. I suspect my iron levels have tanked, though, and going to request some blood panels soon for monitoring and addressing that.

Sorry to hear you’re out of work. The bright side (if you can even call it that) of being unemployed is that at least you’re not forced to be in an office with a lot of people, where the odds of repeated reinfection are astronomically high. Hope it gets better for you.

[–]Sleepyblue 1 point2 points  (2 children)

Same boat here, dev with heavy brain fog. Had you had other boosters before Novavax? I had the Pfizer a few months back which might have helped slightly with the frequency and length of my crashes (although I started a bunch of supplements around the same time, so hard to know for sure), but did nothing for the brain fog. I'd be interested to seek out Novavax if there's something specific to it helping with how utterly stupid LC has made me!

[–]zaleen 7 points8 points  (0 children)

Software Engineer / dev too, fascinating stuff! My brain fog has been unreal too, I feel like I’ve been faking it at work for like a year lol, don’t know how people haven’t noticed! I’ve been terrified to get any other vaccines or boosters (I’ve had 2 and the first booster) as I wasn’t sure that my symptoms didn’t start somewhat after my last booster, then got a lot worse after I caught covid a few months later. Thank you so much for posting here, I’ll be researching this for sure.

[–]yoda13041yr 4 points5 points  (0 children)

I had a Pfizer booster a year before I got LC. There are a lot of patient reports on Twitter saying that the Novavax booster improved brain fog, it's what led me to get it in the first place.

[–]wyundsr 0 points1 point  (2 children)

Did it help with fatigue/PEM too? My brain fog is secondary to physical fatigue and PEM

[–]omibus 0 points1 point  (1 child)

I just don’t do much. I work from home, and if I need a nap I take a nap. My boss and coworkers all know what I’m going thru. Unfortunately that is all I got.

[–]wyundsr 0 points1 point  (0 children)

I was just curious if the Novovax helped with the fatigue and PEM at all or only the brain fog. I’ve also been staying home/working from home.

[–]Sleepyblue 0 points1 point  (1 child)

Does the Propranolol specifically helps with brain fog? Do you know the science behind how it works?

[–]omibus 1 point2 points  (0 children)

I don’t know the science behind it. It mostly helps with all the migraines I get, which in turn helps with my brain fog.

[–]locustbones 24 points25 points  (3 children)

I just did the updated pfizer vaccine 4 days ago and so many of my LC symptoms have diminished. Before I was taking propranolol, Xanax & chlorpenaramine maleate. I can’t tell what did it and I know it’s a gamble getting a vaccine while having LC but I’m choosing to believe that it helped me

[–]schirers 0 points1 point  (0 children)

any update ?

[–]EttaJamesKitty 0 points1 point  (1 child)

Any update to how you feel now?

[–]locustbones 0 points1 point  (0 children)

Symptoms came back, then I did IV ketamine infusions and all symptoms disappeared completely.

[–]DisasterSpinach 21 points22 points  (1 child)

!remindme 1 month

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[–]Comprehensive_Round2 yr+ 7 points8 points  (4 children)

A lot of software developers in this thread. I wonder if we have higher LC prevalence than other professions or we are more likely to be negatively affected by brain fog. I'm guessing the latter.

I also have LC and life became a real struggle with brain fog. I told my team and my manager about it. They were very supportive for the first few months but after that their expectations returned to normal and they started to get irritated at my inability to perform at a continuous 100%.

When layoffs came they couldn't get rid of me fast enough.

Interesting to hear that Novavax has helped people. Once it's available over here I will probably get one and start looking for another job.

[–]Slow_Ad_9872 10 points11 points  (0 children)

Or a higher proportion of software developers on Reddit?

[–]Big_Message_7824 2 points3 points  (0 children)

I’m a speech-language pathologist and brain fog has impacted me significantly, for two years. Improved some and then I got COVID again in Jan. 2023. I’ve been functioning but it’s hard.

[–]zaleen 0 points1 point  (1 child)

Did either of you end up doing it? I'm very interested in how its going for the other devs. My husband and I are both devs. And agreed the brain fog is a real productivity killer, let alone the major motivation issues

[–]Comprehensive_Round2 yr+ 0 points1 point  (0 children)

No I didn't. Apparently there is a big percentage of people who get worse. The risk is just too high.

[–]cloudfairy222 5 points6 points  (7 children)

Can I ask if those of you who are feeling better post novavax had bad reactions from any previous vaccines? I got very sick from the j & j - allergic type reactions including face swelling, pots, extreme fatigue, a rash that lasted 6 months and basically all my other lc symptoms. I had to go on a round of steroids to stop the “auto immune” reaction (doctors words). I’m terrified of the booster but so over all of this.

[–]Mags_Beau 2 points3 points  (1 child)

I have autoimmune issues and had reactions to the Moderna, but no issues with Novavax.

[–]cloudfairy222 0 points1 point  (0 children)

Good to know!

[–]gothictulle 0 points1 point  (2 children)

What is the auto immune reaction mean? I think I have that but can you take a test for it?

[–]zb0t13 yr+ 0 points1 point  (1 child)

You can test for autoantibodies e.g.

I did it.

[–]cloudfairy222 0 points1 point  (0 children)

I mean I have been tested for multiple autoimmune diseases. What text did you have? The doctor just diagnosed me based on my symptoms and treated it with steroids. It worked for most part. Have been seeing a rheumatologist since trying to pin down if it created a chronic condition or was just a reaction

[–]Comane97 0 points1 point  (1 child)

What kind of doctor did you see for this may I ask?

[–]cloudfairy222 0 points1 point  (0 children)

He was an internal medicine doc over teledoc. I got lucky with a doctor who had seen it in other patients. I didn’t have any primary care docs at the time - I’ve since seen 14 doctors/specialists as that and covid set off a whole storm in my body.

[–]InHonorOfOldandNew 5 points6 points  (0 children)

I'm so happy for you!

[–]UnlimitedScaler 24 points25 points  (1 child)

Temporary immune distraction, catching the flu would have the same effect. Report back in one month as many reverse to LC state.

[–]thoughtsinslowmotion 0 points1 point  (0 children)

I don’t experience this. I had one lucid month this year (post Covid 2020) and it happened after another (3rd ) acute Covid infection. Sadly the lucidity only lasted for about 5 weeks and gradually returned. I had flu for 6 weeks a few months ago and nothing happened to the fog… it’s still there.

[–]Dream_Imagination_58 4 points5 points  (0 children)

Congrats- glad to hear this! Definitely keep us posted!

[–]darkmakeslight 4 points5 points  (1 child)

Curious to see more people who have this. Currently debating if i want to get the new Pfizer or the Novavax. Either way I'm terrified of getting worse or more debilitated but living this way is also miserable.

I hate needles and the idea of injecting something I don't understand into my veins, or injecting anything into my veins at all. But this rollercoaster ride has been an exhausting 4 years, I'm thinking if it kills me then it'll be doing me a favor, if i get better than i finally can work towards living again maybe.

[–]Sleepyblue 1 point2 points  (0 children)

I had the Pfizer a few months ago, might have helped slightly with the frequency and length of my crashes but didn't help with the symtoms specifically. I'm curious to hear from anyone who saw a benefit from Novavax after not seeing any from Pfizer.

[–]Some_Shine_2324 2 points3 points  (5 children)

How was your brain fog bro? Any memory problem (like visualizing things)?

[–]LobsterAlpha[S] 19 points20 points  (3 children)

My memory from the last 2 years is very very blurry. I was experiencing things in the moment but barely recollecting them afterwards.

I struggled to focus and found it very hard to start things. Kinda like ADHD. Whenever I tried to think about something complex, I'll start feeling pressure at the back of my head. Sometimes I just have to reduce inputs to my brain (sitting in darkness) to feel better.

And after a full day of work, I'd feel so so hungover.

[–]naycati 1 point2 points  (2 children)

Yep. Have you tried to measure your temperature when that pain starts? I've been finding my temperature goes up when "exercising" my mind

[–]LobsterAlpha[S] 2 points3 points  (1 child)

Haven't measured it but I do get a fever when it starts

[–]naycati 0 points1 point  (0 children)

I've noticed that if I measure in the head, like using an ear or forehead thermometer the temperature rise is more evident than when using an under arm one

[–]JediWitch 19 points20 points  (0 children)

Isn't that fun? Earlier I saw a nod to the game Mortal Kombat in another game. I've been a gamer for 32 years. I run the video game department for a good size charity. I damn well know the name "Mortal Kombat"... Yet I couldn't point it out to my fiance because for the life of me I couldn't think of those two words.

I ran through the characters names, finishing moves, etc. Visualizing the game in detail but it's like a heavy fog was covering the name itself. This happens with very common words as well during conversation and my family has learned to give me time to fight the fog so to speak. I'm less anxious and embarrassed if I manage to do it myself.

[–][deleted] 2 points3 points  (8 children)

So you think getting revaccinated helped your long COVId ??

May I please ask if as a part of your brain dysfunction / brain fog you had any :

Dissasocation/ derealization type symptoms ?

[–]LobsterAlpha[S] 4 points5 points  (7 children)

I definitely felt dissociation. Wasn't able to be fully present anywhere or with myself. Not sure if it's from brain fog or from the depression that came with LC 🙃

[–][deleted] 0 points1 point  (6 children)

Was yours 24/7 ?

And this all went away when you had the nova vax ?

I’m trapped in 24/7 dissasociation due to LC :(

[–]LobsterAlpha[S] 1 point2 points  (5 children)

It wasn't 24/7, mainly post brain exertion.

Might be worth consulting with a psychiatrist/neurologist though. Might not all be LC.

Hoping you get better 🙏

[–][deleted] 0 points1 point  (4 children)

I’ve had a heap of brain scans

Unfortunately it is definitely from LC 😔

Nothing else was wrong prior

& thank you 🙏🏻

[–]Following_my_bliss 1 point2 points  (3 children)

Did your scans show anything? So far all tests are "normal" which is crazy considering the symptoms.

[–][deleted] 1 point2 points  (2 children)

Not at all :) my brain is entirely normal haha

Did you have some too?

[–]Following_my_bliss 1 point2 points  (1 child)

yes, normal :)

[–][deleted] 0 points1 point  (0 children)

Thats good!

How long have you had the 24/7 dissasocation / dpdr for now ??

[–]sweet_beeb2 yr+ 2 points3 points  (1 child)

excellent!! i’m hoping to get the novavax this week. did you have any side effects from it?

[–]LobsterAlpha[S] 2 points3 points  (0 children)

I was sick, mild flu symptoms, the day after and my arm was sore but that cleared up pretty quickly.

[–]Worldly-Marzipan-398 2 points3 points  (0 children)

First of all, super happy for you! And grateful for folks sharing things like this. Damn, I wished I'd worked even harder to find an accessible Novavax shot this fall. I got another Pfizer instead as it was a real struggle where we are to get in on the few places with the Nova's. Keep us posted. And cheers to your really good news!

[–]idkidekidekidk 2 points3 points  (0 children)

Did you have any issues with your emotional range?

[–]InsomniacSpaceJockey 2 points3 points  (0 children)

I sought out Novovax due to Twitter rumors saying it was more effective against the new variants. Didn't change my brain fog but I caught a variant this week and barely got a head cold. Worth the struggle to locate the rare CVS carrying the vax, imo.

[–]Apart-Slice-3589 2 points3 points  (0 children)

Brain fog can be incredibly challenging, especially in a demanding profession like software engineering. It's encouraging to hear that your energy levels are normalizing and that you're able to focus better. Fingers crossed that these positive changes continue for you. Remember, every small win counts on the road to recovery. Stay hopeful and take care!

[–]nokenito 4 points5 points  (3 children)

Where did you get the Novavax vaccine at? I'd like to get this one. The March 2021 Pfizer vaccine helped my Covid March 2020 damaged lungs dramatically.

[–]LobsterAlpha[S] 6 points7 points  (2 children)

I'm in NY. Got it at a rite aid. But the CVS website says all their branches carry it.

[–]nokenito 2 points3 points  (1 child)

Thank you, I made an appointment for Sunday thanks to you!

[–]LobsterAlpha[S] 1 point2 points  (0 children)

Good luck!

[–]Curious-Practice-473 1 point2 points  (3 children)

Yep, my brain fog symptoms also improved after Novavax.

[–]Homesickhomeplanet3 yr+ 1 point2 points  (2 children)

How long ago did you get it? Did the improvement last?

[–]Curious-Practice-473 7 points8 points  (1 child)

So, I'm a man in my 30s. Got Novavax 4 months after my infection. My neurological symptoms were always mild compared to others, I only experienced proper utterly debilitating brain fog once, during a stressful day a month out from my infection. After that, I avoided stress.

Usually my main symptoms were constant sluggishness, slight difficulties with finding words, delay in solving math problems etc. My thoughts felt as if I was walking on sticky asphalt on an average day or working my way through a bog on a bad day. And on good days, I barely noticed that anything was wrong.

It is possible that I was improving by myself. Given time, my brain was forming new connections to account for the lost neurons. Yet just before I had Novavax, I had another stressful day where the sluggishness, the feeling of your thoughts being hindered, of having to put in work to simply process ideas, were undeniable and overwhelming.

It has been more than a year since I had Novavax and I've yet to have a day like that again. There hasn't even been a hint of anything like it. I do have to mention that during the period I took Novavax, I also was temporarily on ADHD medication Concerta for two weeks (I am not diagnosed with ADHD, I was simply experimenting to improve my executive functioning). Maybe the latter changed my neurochemistry a bit.

That being said, it did take me at least half a year after Novavax to feel as if I was fully recovered. It involved intense journalling to recover my linguistic abilities - initially I still had to search for the right words when I was trying to write. I also solved many different math/physics exercises. But crucially, it felt as if any underlying neuroinflammation was gone after Novavax.

I don't feel dulled anymore, nor hindered. I feel as if I'm the old me again. Maybe a bit older, possibly less brilliant, but still myself. Could be I just got used to my new baseline, but who cares. I feel as if my mind can grow and learn.

On the other hand, I still have two new symptoms. I still make more grammatical errors than I used to - it feels as if I should relearn certain basic grammatical rules, as if my past knowledge of them got deleted, but I haven't bothered yet, instead concentrating on vocabulary and creative self-expression. My eyes also still occasionally lose focus and rapidly flicker when I try to intensely read, write and process new info, leading to what I can best describe as a reboot that requires about five seconds to regain my focus. The last time it happened was 6 months ago though.

I'm thankful about my recovery and aware that I got lucky.

[–]Homesickhomeplanet3 yr+ 1 point2 points  (0 children)

Thank you for sharing, this is really good to know! My brain fog is DENSE

[–]zaleen 1 point2 points  (2 children)

Hello I was trying to research this, thanks to your post! And found the below note. Do you happen to know which one you got? (The old or new?)

“An updated Novavax COVID-19 vaccine (XBB) was approved by Health Canada on December 5, 2023.”

[–]Comprehensive_Round2 yr+ 1 point2 points  (1 child)

I think the old one has been withdrawn, because it is not effective against Omicron strains - it was formulated before they existed. Anyone getting Novavax today would be getting the newer version.

[–]zaleen 0 points1 point  (0 children)

Thank you for the confirmation! I think here in Canada Toronto is one of the first to get the new one and those appointments are still a few days away so I’m thinking anyone who tried to get before then would get the older dated one. Because I was super interested in this, I tested last night only to find out this cold that started yesterday is Covid again. Gut wrenching. Hope my LC symptoms don’t get worse. But I guess that resets the clock for when I’ll be eligible for the vaccine too. Sigh. Anyway thx again for info

[–]Regular_Chart553 1 point2 points  (0 children)

The booster also helped me with my head feeling clearer/less painful daily. I suffer from many LC issues, but this was an unexpected improvement from the booster for me. Got long covid after omicron in May of ‘22. This XBB Novavax seems like it helped similarly for me. Next to no reactions the night of booster except for feeling very hot.

[–]Pyma21 1 point2 points  (1 child)

Hi, I did the new novavax yesterday and I had the same "brain clear" feeling. I hope too it will continue like that!

[–]zaleen 0 points1 point  (0 children)

Still clear feeling?

[–]bitingmytail 1 point2 points  (0 children)

I would love an update on this!!

[–]siege4255 1 point2 points  (0 children)

I got the new Pfizer vaccine which didn’t give me any side effects but didn’t really change much of my LC . Still glad to have some protection from reinfection which is my worst nightmare.

[–]eghie42 1 point2 points  (10 children)

I'm on day 3 now and do have the same experience. A clear brain. My POTS also is reduced a lot (around 30% now). Still do have POTS, but not every time anymore and when heart rate goes up, it doesn't go that high anymore.

I had J&J as my first vax and now Novavax.

One thing to keep in mind (personal opinion): I think Novavax can correct the immune misconfiguration from mRna vaxes and maybe even it's autoimmunity. But the effectiveness depends on how much mRna vaxes you got before the Novavax. If you got more mRna, you need more Novavax to correct your immune system for a complete immune reaction.

[–]LobsterAlpha[S] 6 points7 points  (6 children)

Yeah I'm planning to redo my entire vaccination with just Novavax. I had 3 Pfizer rounds before this.

Didn't know about potential immune issues from the mRNA vaccines. Got any links about that?

Also does anyone know how much time you should give between Novavax shots?

[–]eghie42 7 points8 points  (2 children)

There is some research in regards to IgG4 response from multiple boosters of mRNA: https://pubmed.ncbi.nlm.nih.gov/37243095/

Here is also some research in comparing vaccines: https://www.biorxiv.org/content/10.1101/2022.03.18.484953v1

citation: "mRNA vaccinees had substantial declines in neutralizing antibodies..." (Neutralizing antibodies are responsible for blocking the entry of a pathogen into a cell so that it is firstly unable to infect healthy cells and unable to replicate).

Some concerns on mRna:

https://www.nature.com/articles/s41586-023-06800-3

https://www.science.org/content/article/mrna-vaccines-may-make-unintended-proteins-there-s-no-evidence-harm

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1081933/full

Here about the novavax it's impact on immunity against covid in the nasal area (they are currently in the process of creating nasal vaccines for this as well): https://www.science.org/doi/10.1126/sciimmunol.adg7015

Some other research articles interesting to read on this:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108562/

https://www.nature.com/articles/s41467-023-36686-8

https://www.medrxiv.org/content/10.1101/2022.11.18.22282414v1.full

https://www.journalofinfection.com/article/S0163-4453(22)00548-5/fulltext00548-5/fulltext)

The immune issues are definitely NOT for everyone and of the change of it, I don't know either. But if you're struggling with Long Covid and the mRNA technology can't help, you might want to go for a more traditional well proven vaccine technology, like Novavax.

Non vaccinating is also an issue
Covid virus seems to deplete CD4, like HIV also does. Being unvaxed is therefor also dangerous even though the symptoms might look like a cold.

[–]schirers 1 point2 points  (1 child)

for me it depletes totally different cells

[–]eghie42 0 points1 point  (0 children)

Also CD8 has been noticed, but which ones in your case?

Having covid before vaccination also can reduce the immune response to a vax: https://www.nih.gov/news-events/news-releases/sars-cov-2-infection-weakens-immune-cell-response-vaccination

[–]LilyM1987 1 point2 points  (0 children)

I've read it's 8 weeks between Novavax shots.

[–]My1stNameisnotSteven -4 points-3 points  (1 child)

Bro, you’re doing good.. do not listen to bullshit!😂 Man even trusted Johnson & Johnson 1 shot, knowing damn well J&J will intentionally injure and close the company b4 you can ever sue.. he will not be back with links, and if he does, it’ll be some political Qanon horseshit.. 🤣Remember, these people tried horse paste b/c of Don Trump who invented “Operation Warp Speed” .. smh

You’re recovering bro .. keep going! 🙌

[–]schirers 1 point2 points  (1 child)

updates on your symptoms?

[–]eghie42 0 points1 point  (0 children)

Sure. The clear head stayed. I still can think clearly, which is amazing. My general symptoms which I still have improved, in the sense that the frequency lessened.
I still do have have them, POTS (still seriously awful), a bit of PEM (only now results in tiredness), numb legs/blue veins/blood pooling/etc (almost gone).

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    [–]analogsquid 0 points1 point  (0 children)

    !remindme 1 month

    [–]spiritualina 0 points1 point  (0 children)

    This is great news!! Thanks for posting and please keep us updated 😀

    [–]Remarkable-Cry7838 0 points1 point  (1 child)

    What is this?

    [–]darkmakeslight 2 points3 points  (0 children)

    Novavax is an alternative to the mRNA vaccines

    [–]Sleepyblue 0 points1 point  (2 children)

    This is awesome to hear!! Had you had any other vaccines since having LC or was this the first? I had the Pfizer a few months ago, but it didn't help massively. I'm wondering if Novavax is potentially more efficient - specifically for brain fog!

    [–]LobsterAlpha[S] 1 point2 points  (1 child)

    First vac. I had gotten 3 pfizers before catching the COVID that gave me LC tho

    [–]Sleepyblue 0 points1 point  (0 children)

    Same! Plus one Moderna.

    [–]nondescriptshadow 0 points1 point  (1 child)

    I felt good after the vaccine as well but I think I did too much too soon and crashed quickly. If I were to do it again, I would wait 2 weeks and see if it remains stable

    [–]LobsterAlpha[S] 2 points3 points  (0 children)

    Doing too much rn so I'll try to take it easy 😪

    [–]longhaullarry 0 points1 point  (2 children)

    hey OP! So its been a month, how do you feel? did it last? whats the story as of today?

    [–]LobsterAlpha[S] 0 points1 point  (1 child)

    I updated the original post. Basically still better but some symptoms still returned.

    [–]longhaullarry 0 points1 point  (0 children)

    sorry some returned :( but overall improvement is positive

    [–]TemporarySign898 0 points1 point  (1 child)

    I’m going try the Novavax. Getting in the car right now

    [–]LobsterAlpha[S] 1 point2 points  (0 children)

    Rooting for you!