I bought injectable aqueous suspension ISRIB 10mg/ml.

I’m taking ISRIB for it’s potential cognitive benefits.

First day: Injected 20mg subcutaneously during the day and another 10 mg just before bed, no effect, except in the middle of the night I felt very stimulated.

Second day: 30 mg subcutaneously, no effect, so far.

Can anyone who has successfully used ISRIB tell me how long it took for it to work for them? Would appreciate it.

I already know that marijuana shouldn't be used alongside ISRIB-A15. I made that mistake. But I'm unsure of what else should be avoided and for how long before or after ISRIB-A15 something is safe to take. I'm unsure if there even is a time limit for after, or if you need to avoid many substances indefinitely, lest you lose your ISRIB-A15 benefits.

I've heard caffeine is safe, but aside from that and marijuana I have no idea. I've even been avoiding amino acid supplements. I'd like to use kava for anxiety, but I'm unsure if I should, and if so, how long before/after ISRIB-A15 would be safe. If it matters, I usually do ~20-25mg held under my tounge for 5 or so minutes before swallowing.