I am in a very different life situation (single guy, 24), but I also made the move from GTA to Vancouver early this year. Immediate change: I do a lot more stuff outdoors. In Toronto (Danforth), everything felt a little too far away, even with a car. Here, no car, I can still get to a ski hill/hike within an hour. The food scene (I love eating out) is different but still great. Less diversity, but asian food in general is quite good. Both cities are about equal in terms of events, but Toronto has a slightly "easier to find" nightlife.

I thing I would say is if you're renting, it might be hard to find a place that allows pets. You might have trouble finding a place that does. Other than that, I don't see many problems you may face as long as you budget well enough (then again your household income is 250k). Vancouver is in general a pretty nice place to live. Similar is quality of life to Toronto, but different in obvious ways.