I take Pregablin/Lyrica 50mg PRN for chronic pain.
I enjoy exercising. However, my DOMS/pain after exercise has worsened recenty, leading to exercise intolerance. The only thing that helps me post-exercise is Pregablin.
Question: Does Pregablin impact exercise gains in any way? If so, does Gabapentin also ?
I am clarifying because NSAIDS can curtail inflamation necessary for muscle growth and vitamin C can reduce the insulin sensitising effects of exercise.
Thank you
History: 33F chronic pain & fatigue, PCOS.
Daily meds: Metformin 1000 mg, LDN 4.5 mg
Hello! ❗Just a starting statement, I am at no risk to myself, I've been there and done that with self harm and vowed to never go there again. I have a very good support network and I am very honest with my partner about how I am feeling.❗
I'm on 50mg X3 a day of pregabalin. Not been on them too long, I've only just doubled the dose from 25 to 50 last Friday 🫠 but it has been VERY effective for my recent sciatica nerve pain (other details about me and my situation down below).
I've had quite a lot of really bad self harm thoughts - I'd even call them cravings, and, a few 'it wouldn't hurt this much if I didn't exist' thoughts when my pain is really bad. It's upped since I went to 50mg which makes sense, I just wanted to see if anyone had the same thing and it went away - I don't know whether to white knuckle it until it's done, if it ever will be. I know it says to talk to your GP/doctor if these side effects turn up, but I am of the opinion I'd rather battle this for a short amount of time then go back to the pain 😞 but I do want to be realistic. So I'd really appreciate some insight into other people's experiences with pregabalin and any of the above side effects you may have had too.
Other deets, for info/background;
Pregabalin was suggested by my rheumatologist (and historically by my neurologist) to help with my pain levels. I've got idiopathic intracranial hypertension, chronic migraines, 2 prolapsed discs in my neck (4-5, 5-6 but not pressing on anything), chronic fatigue, slightly hyper mobile joints (I'm quite flexible but it's causing issues now I think) very likely fibromyalgia too (rheumatology just wants a few more blood tests on top of what chronic fatigue clinic has done, scores 16/18 tender spots, but the ones I didn't I had botox treatment for migraines done a week prior) - and recently my sciatic nerve has become the bane of my life for no reason. I've pretty much got a constant migraine, and pain in my limbs/joints/random pain across my body, I have a high threshold for pain unfortunately which I'm sure is not a rarity here.
I'm also on duloxetine 30mg, acetazolamide 250mg SR X2, omepralzole 20mg, propanol when and if, zapain when and if, sumatriptan when and if and recently some diazapam to relax muscles but it's not on repeat and tbh doesn't do much.
Sorry for the essay 🥔 and thank you to the mods who responded to my message - I would respond back but I've lost our message into the void 🌌🐙