Sele
Sele may refer to:
Places
People with the surname
E-selectin
E-selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), is a cell adhesion molecule expressed only on endothelial cells activated by cytokines. Like other selectins, it plays an important part in inflammation. In humans, E-selectin is encoded by the SELE gene.
Structure
E selectin has a cassette structure: an N-terminal, C-type lectin domain, an EGF (epidermal-growth-factor)-like domain, 6 Sushi domain (SCR repeat) units, a transmembrane domain (TM) and an intracellular cytoplasmic tail (cyto). The three-dimensional structure of the ligand-binding region of human E-selectin has been determined at 2.0 Å resolution in 1994. The structure reveals limited contact between the two domains and a coordination of Ca2+ not predicted from other C-type lectins. Structure/function analysis indicates a defined region and specific amino-acid side chains that may be involved in ligand binding. The E-selectin bound to sialyl-LewisX (SLeX; NeuNAcα2,3Galβ1,4[Fucα1,3]GlcNAc) tetrasaccharide was solved in 2000.
Taylor
Taylor may refer to:
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Taylor, Missouri
Taylor is an unincorporated community in northeastern Marion County, Missouri, United States. It is located at the northern junction of U.S. Routes 24 and 61. It is about five miles west of Quincy, Illinois and eight miles north of Palmyra.
The community is part of the Hannibal Micropolitan Statistical Area.
Coordinates: 39°56′17″N 91°31′26″W / 39.93806°N 91.52389°W / 39.93806; -91.52389
Taylor sept
Taylor is a sept ("branch") of Clan Cameron, a Scottish clan. Present day members of the Taylor sept hold the Scottish surname Taylor.
Sept namebearer
Some members of the Taylor sept are descendents of Donald Cameron ('Taillear Dubh na Tuaighe'), who lived in the Scottish Highlands Lochaber area ("Cameron country") circa mid 16th century. Others, with no documented connection to Taillear Dubh na Tuaighe or the Clan Cameron, are simply descended from those with an occupational surname meaning tailor. Though Donald's father was XIV Chief of Clan Cameron, Donald, born out of wedlock, could not inherit the title. Nursed by a tailor's wife, Donald received the nickname An Taillear Dubh (an, a diminutive; Taillear, an occupational reference to the caretaker's husband; Dubh, translated as "black" in the context of meaning "swarthy" or "dark tempered") as an infant.
As a young man, Donald became skilled in battle with the Lochaber axe, and his nickname evolved to Taillear Dubh na Tuaighe ("Black Taylor of the Axe") because of his fighting prowess. Taylor and his family eventually found safety in Cowal. There, descendents of his family and followers became known as Mac-an-taillear ("son of the tailor").
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