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We Are Building a Future Free of Age-Related Disease

SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. We are redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists.

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Research

Discover the science behind our strategies to extend a healthy lifespan.

Education

Training a new generation of scientists to tackle the roots of age-related disease.

Outreach

Keep up to date on SRF’s latest news and activities.

Research Highlight -

SRF MitoSENS team published on the Present and Future of Mitochondrial Therapeutics

We are proud to announce the publication of our review article “The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics” in Biomedicines, from our very own Dr. Amutha Boominathan and members at SENS.

Mitochondria are important organelles in the cell that generate energy from nutrients. The fitness of mitochondria throughout the lifespan is paramount and loss of mitochondrial function is linked to several age-related diseases as well as the aging process itself. In this review, the authors discuss the state of the art of “allotopic expression” (aka gene therapy for mtDNA proteins) and its potential to become an indispensable tool in restoring mitochondrial health in disease and aging.

In this review, we discuss the current therapeutic landscape in addressing the various pathologies that result from mtDNA mutations. We further evaluate existing gene therapy efforts, particularly allotopic expression and its potential to become an indispensable tool for restoring mitochondrial health in disease and aging.

Learn more about the paper

Outreach Highlights -

SRF Celebrates Women’s History Month

Throughout history, women interested in science and engineering have broken barriers to make important discoveries, conduct game-changing research, and pursue careers in science, technology, engineering, and math (STEM). 

SRF encourages the development and support of women in longevity research, both as scientists and as administrators and support personnel. Our Education program teaches the next generation of young women to follow their dreams and make new discoveries to drive our field forward.

We are proud to present the many women of SENS Research Foundation, including our researchers, executive, and administrative teams. SRF is currently 100% female-led internally, with an all-women Senior Staff Team and Chairperson on the Board of Directors. While it does take the entire community of SRF staff and supporters to move our mission forward, this month we are thrilled to highlight the women who continue to drive our progress in longevity research.

Please visit the Team section of our website to learn more about the amazing women of SRF.

Read more
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Education Highlight -

2022 Postbaccalaureate Fellowship Program Applications Open

Thanks to all of you who have been patiently waiting for SRF Education updates. We are currently undergoing some restructuring, and working to make our student internship and enrichment programs better than ever.

We are happy to announce that we have now opened applications for the 2022 Postbaccalaureate Fellowship program. Please visit the program homepage for details, eligibility requirements, and to apply.

Applications will be now accepted until noon PST on Friday April 1, 2022.

A list of host laboratories will be posted as soon as we have it available.

Program Homepage

News:

Michael Rae and Dr. Robert Rodgers discuss Parkinson’s and aging

SENS Research Foundation’s science writer Michael Rae was interviewed on the Parkinson’s Recovery radio program on “The coming rejuvenation biotechnology revolution for Parkinson’s disease.” In it, they discussed how the cellular and molecular damage of aging most closely involved in Parkinson’s can be removed, replaced, or repaired using rejuvenation biotechnologies, and research underway to make it happen.Read more and listen to the interview to learn how a “damage-repair” approach can prevent, arrest, and eventually consign Parkinson’s to history.

SENS Research Foundation & Underdog Pharmaceuticals jointly awarded $252,000 NIA research grant

The National Institute on Aging (NIA) division of the National Institutes of Health (NIH) has awarded a grant to advance research on Engineered Cyclodextrins targeting toxic oxidized cholesterol to eradicate atherosclerosis — the cause of most heart attacks and strokes.

Former SRF V.P. of Research and current Underdog Co-founder Matthew O’Connor, Ph.D. and current SRF V.P. of Research Alexandra Stolzing, Ph.D., are the Principal Investigators.

SRF’s researchers presenting our work at Indian biosciences conferences

Our VP of Research Dr. Alex Stolzing and Senescence Immunology Research Group Lead Dr. Amit Sharma will be presenting at conferences in India this week, including at the 35th Annual Conference of Aging Interventions, organized by the Society of Neurochemistry, India (SNCI), and the Darwin International Conference.

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