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Chronic wasting disease spotted in South Dakota's Buffalo County
PIERRE – Chronic wasting disease (CWD) was recently confirmed in a new area in central South Dakota. Confirmation of the disease was obtained from a hunter-harvested adult female white-tailed deer in Buffalo County. South Dakota has
Dr. Robert Young: Graphene Ribbons, Nano Networks, EMF Effects & True Cause of Disease
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Billy Connolly reveals he can’t use his left hand anymore due to Parkinson’s disease and ...
BILLY Connolly revealed he can no longer use his left hand to play musical instruments because his Parkinson's makes him shake so much. The comedy legend has remained stoic
Cytonus Therapeutics Announces Publication in Nature Biomedical Engineering of Preclinical Results to Support Disease-Specific Drug-Delivery ...
Maryville Daily Forum | 2021-12-21, 22:42
SAN DIEGO--(BUSINESS WIRE)--Dec 21, 2021-- Cytonus Therapeutics Inc., a US-based biotechnology company developing an innovative drug-delivery platform technology called Cargocytes, today announced the publication of a peer reviewed research paper in the high
Glaxosmithkline's HIV jab is approved by US regulators
An injectable drug made by Glaxosmithkline that prevents HIV has been approved by
FDA Approves Bimonthly HIV Prevention Shot More Effective Than Existing PrEP Medications
The US Food and Drug Administration (FDA) federal regulatory agency has approved Apretude as the nation’s first injectable pre-exposure prophylaxis (PrEP), a medication that prevents infection from Human Immunodeficiency Virus (HIV). ...
Cure for vaccine injuries! Protocol to remove graphene oxyde etc..
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Glaxosmithkline's HIV jab is approved by US regulators and it is found to be more ...
An injectable drug made by Glaxosmithkline that prevents HIV has been approved by US regulators. The Food and Drug Administration (FDA) became
NIH celebrates FDA approval of long-acting injectable drug for HIV prevention (NIH - National Institutes of Health)
) News Release Tuesday, December 21, 2021 NIH celebrates FDA approval of long-acting injectable drug for HIV prevention Approval marks pivotal expansion of HIV prevention options in the United States. Scanning electron micrograph of an HIV-infected H9 T
Dr. Judy Mikovits: Fear Is the Virus, Love Is the Cure
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A New, Long-Acting HIV Prevention Drug Just Got FDA Approval
The Food and Drug Administration has approved a new
Pandemic causes ‘creative work’ to help those with dementia, Alzheimer’s disease
Cascade Business News | 2021-12-21, 21:46
The pandemic has created challenges in many walks of life, including those with Alzheimer’s disease or any form of dementia, their families and their caregivers. Grace Knorr, a social worker at the Cleveland Clinic Lou Ruvo Center for Brain Health, has
Public Health (Control of Disease) Act 1984 & Mandatory Vaccination
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Covid – disease of vaccinated or unvaccinated?
Dear Editor, Serena Hunter (in her letter on December 11 – No jab, no job policy) wrote that “Gibraltar, population of 33,000, over 118% vaccinated (beat that), and facing a surge in cases”. She used this with similar situations in other countries to conclude
NIH celebrates FDA approval of long-acting injectable drug for HIV prevention
Yesterday the U.S. Food and Drug Administration announced its first approval of a long-acting HIV prevention medication. Developed by ViiV Healthcare, the medicine is long-acting cabotegravir injected once every two months. FDA has approved the medicine for
Woman shares ‘beautiful’ moment she informed her father with Alzheimer’s that she was pregnant
A woman has shared the heartwarming moment that she told her father with Alzheimer’s that she was pregnant after three years of fertility
Coronavirus Disease (COVID-19): Weekly Epidemiological Update (21 December 2021)
During the week 13-19 December, the global number of new cases remained similar to those reported during the previous week (Table 1 in the PDF); however, the weekly incidence of deaths decreased by 9%. Nonetheless, this corresponds to over 4.1 million new
HPTN Studies Inform FDA’s Approval of ViiV Healthcare’s Long-Acting Cabotegravir Injections for HIV Prevention
DURHAM, N.C., Dec. 21, 2021 (GLOBE NEWSWIRE) -- Data from the HIV Prevention Trials Network (HPTN) studies HPTN 083 and HPTN 084 helped provide
TRC Gen+ Clinical Research Shows Nic's KetoDiet Reduces Risks of Cardiovascular Disease in Individuals with ...
A study conducted by Prof. Tzenios and KGK
'Design and Healing' Shows How Epidemics Lead to Innovation
“Design and Healing” at the Cooper Hewitt shows adaptations to disease through history that shaped health care, behavior and the form of buildings. ...
FDA approves first long-acting injectable treatment for HIV prevention
The US has approved a long-acting pre-exposure prevention treatment (PrEP), named Apretude, to help people avoid HIV infection. The FDA announced on Monday that Apretude (cabotegravir
ADx Health released compelling data in their GenoRisk™ manuscript: A polygenic risk score for Alzheimer's ...
Victoria Advocate | 2021-12-21, 20:08
LARKSPUR, Calif. , Dec. 21, 2021 /PRNewswire/ -- Alzheimer's disease (AD) is notoriously difficult to treat. Part of the reason for these failures is the high heterogeneity across the disease that presents with diverse clinical symptoms and progression
Global Orphan Diseases Partnering 2021: Deal Trends, Players and Financials - ResearchAndMarkets.com
Herald-Standard | 2021-12-21, 19:47
DUBLIN--(BUSINESS WIRE)--Dec 21, 2021-- The "Global Orphan Diseases Partnering 2010-2021: Deal Trends, Players and Financials" report has been added to ResearchAndMarkets.com's offering. Global Orphan Diseases Partnering 2010 to 2021 provides the full
ADx Health released compelling data in their GenoRisk™ manuscript: A polygenic risk score for Alzheimer’s ...
LARKSPUR, Calif. , Dec. 21, 2021 /PRNewswire/ -- Alzheimer’s disease (AD) is notoriously difficult to treat. Part of the reason for these failures is the high heterogeneity across the disease that presents with diverse clinical symptoms and progression
Alzheimer's Drug Discovery Foundation (ADDF) and Target ALS Announce Partnership to Accelerate Biomarker Discovery and Development
The Salamanca Press | 2021-12-21, 19:38
NEW YORK, Dec. 21, 2021 /PRNewswire-PRWeb/ -- The Alzheimer's Drug Discovery Foundation (ADDF) and Target ALS announced today a new partnership to identify and develop biomarkers for neurodegenerative diseases, including Alzheimer's disease (AD), Amyotrophic
Women account for two-thirds of HIV-related arrests in Kentucky, report finds
Women in Kentucky are disproportionately affected by the state’s HIV criminalization laws, according to a new report. ...
Biogen cuts the price tag on its Alzheimer’s drug in half
Biogen is slashing the price of its Alzheimer's treatment in half months after it debuted to widespread criticism for an initial cost that could reach $56,000 annually. ...
ADx Health released compelling data in their GenoRisk™ manuscript: A polygenic risk score for Alzheimer's disease, which was published in Alzheimer's & Dementia: Translational Research & Clinical Interventions, a journal of the Alzheimer's Association, and provided valuable scientific data linking personalized genetic testing to the predictive risk of Alzheimer's disease
LARKSPUR, Calif. , Dec. 21, 2021 /PRNewswire/ -- Alzheimer's disease (AD) is notoriously difficult to treat. Part of the reason for these failures is the high heterogeneity across the disease that presents with diverse clinical symptoms and progression
It’s time to treat substance abuse like a chronic disease (UC Davis Health System)
) (SACRAMENTO) While concern over the COVID-19 pandemic has dominated the headlines over the past year, another public health crisis has been lurking in plain sight: the drug epidemic. The U.S. Centers for Disease Control and Prevention estimates that more
FDA approves new HIV prevention drug taken by injection every two months to replace daily ...
The Food and Drug Administration (FDA) has approved a new drug for HIV prevention that may be easier to take for many patients This new drug, called Apretude, is taken by injection every two months. It could replace daily pills, which are challenging to take
Clients scramble for shelter as HIV program in limbo
Atlanta Journal | 2021-12-21, 18:50
Just two weeks after David Perdue
First injectable HIV prevention drug gets FDA approval
The US Food and Drug Administration (FDA) has approved the first injectable prevention medication for HIV, offering an alternative to pre-exposure preventative tablets. The new drug, Apretude, is administered to patients every two months via injection. In
FDA approves first injectable form of HIV prevention medication
Midland Daily News | 2021-12-21, 18:32
when the cure is identical to the disease
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Eamon O’Connell: Vaccines, drying off and ‘wonder cures’ – crucial lessons I’ve learned in 2021
I picked up my young lad from school yesterday and, as is our ritual on the drive home, I asked him to tell me something he had learned that day. Sometimes it’s simple and sometimes it’s more long winded, but most importantly,
FDA approves first-ever injectable to prevent HIV
The Food & Drug Administration (FDA) approved a new drug Monday that will allow patients to ditch the daily pill and receive treatment every two months. The drug, named Apretude, is being considered the first long-acting injectable medication for use as
Dr. Judy Mikovits: Fear is the virus, love is the cure – Brighteon.TV
(Natural News) Former researcher Dr. Judy Mikovits told
The FDA Just Approved the First Injectable HIV Prevention Drug
The U.S. Food and Drug Administration for use as pre-exposure prevention, or PrEP, against HIV, has been approved. The long-acting drug, Apretude, is intended to reduce the risk of HIV transmission through sex among adults and teenagers who weigh at least 77
Women offered preventive health screenings and chronic disease management through Well Woman Program in Barbour and Henry counties (State of Alabama)
) FOR IMMEDIATE RELEASE CONTACT: Barbour County Health Department, (334) 687-4808 Henry County Health Department, (334) 585-2660 The Barbour and Henry county health departments in the Southeastern Public Health District currently offer a program called Well
Is untreated HIV behind emergence of Omicron?It has already been observed that Covid-19 can linger ...
The hypothesis that the emergence of new Covid-19 variants could be linked, in some cases, to untreated HIV is "highly plausible", according to South African scientists. To explore the link, a team of scientists have launched a probe into mutations taking
Edward Jones Surpasses $30 Million Goal to Advance Alzheimer's Research
The Joplin Globe | 2021-12-21, 16:52
ST. LOUIS, Dec. 21, 2021 /PRNewswire/ -- Financial services firm Edward Jones announced it has raised more than $30 million since 2016 toward the fight against Alzheimer's, with support for more than 600 walks and more than 11,000 Walk to End Alzheimer's
Germany’s disease control agency advises tougher curbs to fight omicron
Germany’s disease control agency on Tuesday called for tougher restrictions to prevent a new surge in coronavirus infections. The Robert Koch Institute (RKI) said stricter rules were now necessary to fight the omicron variant, which is spreading
FDA approves first HIV prevention injection
The Food and Drug Administration (FDA) has approved the first injectable treatment for HIV pre-exposure prevention (PrEP), providing another option to help individuals at-risk avoid sexually transmitted HIV. The drug, called Apretude, will be available to
TRC Gen+ Clinical Research Shows Nic’s KetoDiet Reduces Risks of Cardiovascular Disease in Individuals with ...
LONDON, Dec. 21, 2021 (GLOBE NEWSWIRE) -- to examine the efficacy of Nic’s Keto Diet (NKD), a very-low-carbohydrate ketogenic diet, on cardiovascular health in adults with mildly elevated LDL cholesterol.ADVERTISEMENT The , called Nic’s Keto Diet (NKD), on
A woman starting to suffer from Alzheimer’s is missing. Miami police want your help
Ionian Regalado is 52 years old and is dealing with schizophrenia and the early stages of Alzheimer’s disease. She lives in the Wynwood area, but also likes the Little Havana ...
Man charged with cannibalism believed eating victim would 'cure his brain'
A demented man was arrested in the US with charges of cannibalism after police said he tortured an aged victim and microwaved his body parts before eating the body to ‘cure his brain’. The incident took place in the Bonner County in the state of
Novaremed’s Non-opioid Lead Compound, NRD.E1, to be Tested in NIH HEAL Initiative Phase 2 Trial ...
Hastings Tribune | 2021-12-21, 15:53
BASEL, Switzerland--(BUSINESS WIRE)--Dec 21, 2021-- Novaremed AG, a privately held clinical-stage biopharmaceutical company, announces a study with the National Institutes of Health (NIH) under which the NIH will sponsor and conduct a clinical Phase 2b study
As Told To: 'Being HIV-positive enabled me to find a real passion and life purpose'
Christian Hui is a Toronto-based HIV+ activist and social worker who is dedicated to bringing awareness to HIV stigma and the importance of treatment. He is the Knowledge Exchange and Network Engagement Lead at the Ontario Harm Reduction Network (OHRN),
FDA Approves First Injection Regimen for HIV Prevention
Calhoun Times | 2021-12-21, 15:47
TUESDAY, Dec. 21, 2021 (HealthDay News) -- The first injection drug to prevent HIV infection was approved by the U.S. Food and Drug Administration on Monday. ...
Bayer receives positive CHMP opinion for finerenone as a new treatment for patients with chronic kidney disease and type 2 diabetes
Bayer receives positive CHMP opinion for finerenone as a new treatment for patients with chronic kidney disease and type 2 diabetes Finerenone, the first non-steroidal, selective mineralocorticoid receptor (MR) antagonist,1 is recommended by the CHMP for
Mechanical forces in a beating heart affect its cells' DNA, with implications for development and disease
Richmond Times Dispatch | 2021-12-21, 15:30
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) ...
VACCINE ENHACED DISEASE ADMITTED IN CONFIDENTIAL REPORTS
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GlaxoSmithKline’s long-acting HIV drug Apretude approved by US regulator
The US regulator has approved the first long-acting injectable medicine to prevent HIV, a milestone in the battle against the
New Seed Treatment Sets Higher Standard of Control for Peanut Disease (Syngenta Corporation)
) The text version of this document is not available. You can access
Scammers posing as Melania Trump promote weight loss pill as COVID cure
Telegram channels posing as prominent right-wing figures are hawking a supplement that supposedly prevents COVID-19. Some of the channels even claim that the supplement, Meticore, "will kill every infection." "Only 6 bottles to better health and protection
Multiple Sclerosis Drugs Market Report Up to 2031: Visiongain Research Inc
Visiongain has published a new report on Multiple Sclerosis Drugs Market Report 2021-2031:Forecasts By Drug Class (Corticosteroids, Interferon
Save the Date – “Healing Our Connection With Food In The Fake Food Era” at #ORFC2022
Oxford Real farming Conference Session 5 January 2022, 2pm – 3.30pm GMT Speakers Vandana Shiva, Navdanya Satish Kumar, Resurgence Trust Moderator: Ruchi Shroff, Navdanya International We live in an era where our connection with food and with the communities
"Our hydroponic systems use Spacer, prevents excess moisture and proliferation of root diseases"
Sustainability is one of the aspects most pursued by the agri-food industry and one of the most demanded by consumers. It is the cornerstone of both the evolution of the sector as a whole and of new developments, including hydroponics, which is gaining more
Wine Condom Creator Can’t Get Media Coverage For COVID Cures
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Coronavirus-Nigeria: Accelerating COVID-19 vaccination uptake among People Living with HIV in Nigeria
Download logo The emergence of the COVID 19 omicron variant, has continued to rage, with attendant consequences. The situation is posing an even greater strain on progress with ending AIDS, disrupting HIV prevention and treatment services, schooling, violence
If Peeps in Wash DC Would Stop Having Legal Sex w/Animals, Would All This Disease ...
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Towards Zero: the HIV Action Plan for England - 2022 to 2025 (UK Department of Health & Social Care)
) Policy paper Towards Zero: the HIV Action Plan for England - 2022 to 2025 The plan sets out how we will achieve an 80% reduction in new HIV infections in England by 2025. From:Department of Health and Social CarePublished1 December 2021Last updated 21
Accelerating COVID-19 vaccination uptake among People Living with HIV in Nigeria (WHO - World Health Organization Regional Office for Africa)
) Accelerating COVID-19 vaccination uptake among People Living with HIV in Nigeria 21 December 2021 Abuja, 21 December 2021- The emergence of the COVID 19 omicron variant, has continued to rage, with attendant consequences. The situation is posing an even
FDA approves first injectable PrEP medication to lower HIV risk
FDA approves first injectable PrEP medication to lower HIV risk ...
Women's mental health service to provide safe space for healing in Victoria
Women's mental health service to provide safe space for healing in Victoria ...
Diabetes, Thyroid, Arthritis, Headache & Covid-19 Cured Following DIP Diet and 3 Step Flu Diet
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Is untreated HIV behind emergence of Omicron?
London, Dec 21 : The hypothesis that the emergence of new Covid-19 variants could be linked, in some cases, to untreated HIV is "highly plausible Source:TeluguStop.com Read More.. ...
'Aleppo boil' disease infects thousands in northeast Syria
Cases of a disease known as "Aleppo boil" have soared across northeast Syria in recent months due to a lack of insecticides, according to a member of the Kurdish Red Crescent, a local medical NGO. The disease, officially named Leishmaniasis, is caused by a
Peripheral Artery Disease Market Growth, Key Business Strategies, and Covid-19 Impact Analysis - 2027
(MENAFN - EIN Presswire) The peripheral artery disease market is expected to reach $5,715.12 million by 2027, registering a CAGR of 8.5% from 2020 to 2027. PORTLAND, OREGON, US, December 21, 2021 ... ...
Claritas Completes Acquisition of Exclusive Worldwide Rights to Develop and Commercialize R-107 for Pulmonary Disease
(MENAFN - GlobeNewsWire - Nasdaq) SAN FRANCISCO, CA and TORONTO, ON, Dec. 21, 2021 (GLOBE NEWSWIRE) -- Claritas Pharmaceuticals, Inc. (TSX VENTURE: CLAS and OTC: KALTF) (the ' Company ' or ' ... ...
Covid-19, Cough and Cold Cured following 3 Step Flu Diet
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Do This Daily To Naturally Reverse Cavities & Heal Tooth Decay
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Cognition Therapeutics to Participate in Next-Generation Alzheimer’s Disease Panel at Virtual ...
Kentucky New Era | 2021-12-21, 13:34
PURCHASE, N.Y., Dec. 21, 2021 (GLOBE NEWSWIRE) -- Cognition Therapeutics, Inc. (Nasdaq: CGTX), a clinical-stage biopharmaceutical company engaged in the discovery and development of innovative, small molecule therapeutics targeting age-related degenerative
Across China: China increases accessibility to rare disease treatment
A nurse is giving an injection to a kid patient at the Sichuan Provincial People's Hospital on Dec. 15.(Xinhua/Dong Xiaohong) CHENGDU, Dec. 21 (Xinhua) -- Two-and-half-year-old Xuanxuan survived a rare kidney disease in early December, thanks to fast-track
DIABETES GOT CURED BY FOLLOWING DIP DIET
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FDA approves first injectable drug to prevent HIV
The Food and Drug Administration announced Monday it approved a new injectable medication, Apretude, to lower HIV risk. ...
Novaliq Announces POSITIVE Topline Results for SECOND PHASE 3 TRIAL (ESSENCE-2) of CyclASol® in Dry Eye Disease
HEIDELBERG, Germany, and CAMBRIDGE, Mass, Dec. 21, 2021 /PRNewswire/ -- Novaliq, a biopharmaceutical company focusing on first- and best-in-class ocular therapeutics based on the unique EyeSol® water-free technology, today announced key results of the second
XORTX Therapeutics Announces Filing of Provision Patent for Polycystic Kidney Disease (XORTX Therapeutics Inc)
) News & Events Overview Press Releases IR Calendar Email Alerts XORTX Therapeutics Announces Filing of Provision Patent for Polycystic Kidney Disease December 21, 2021 7:00am EST • Increased Xanthine Oxidase Expression in ADPKD Kidneys • CALGARY, Alberta,
XORTX Therapeutics Announces Filing of Provision Patent for Polycystic Kidney Disease - Form 6-K (XORTX Therapeutics Inc)
) XORTX Therapeutics Announces Filing of Provision Patent for Polycystic Kidney Disease · Increased Xanthine Oxidase Expression in ADPKD Kidneys · CALGARY, Alberta, Dec. 21, 2021 (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. ("XORTX" or the
Millions of Somalis Facing Conflict, Drought, Disease Need Lifesaving Assistance
Geneva -- The United Nations estimates 7.7 million people, half of Somalia's population, will require humanitarian assistance and protection in 2022.It is appealing for $1.5 billion to assist 5.5 million of the most vulnerable among them. ...
Accelerating COVID-19 vaccination uptake among People Living with HIV in Nigeria
WHO personnel sensitizing PLHIV on COVID-19 vaccine. © WHO Abuja, 21 December 2021- The emergence of the COVID 19 omicron variant, has continued to rage, with attendant consequences. The situation is posing an even greater strain on progress with ending AIDS,
The UK-based MS Society funds global research into the treatment and prevention of multiple sclerosis.
The UK-based MS Society funds global research into the treatment and prevention of multiple sclerosis. ↩︎ MS Society View Post → ...
Biogen cuts Alzheimer’s drug price 50% months after approval
Biogen said it would cut the wholesale price of its Alzheimer's disease drug Aduhelm in half in the U.S. — to $28,200 a year — in a move that comes after the treatment's high cost spurred concerns that it could strain Medicare and insurers. ...
Family in Nigeria Lost 3 Daughters to Sickle Cell. Can They Save a Fourth?
About 150,000 babies are born each year in Nigeria with sickle cell, a deadly disease. Tens of thousands of them die annually before their fifth birthdays. ...
XORTX Therapeutics Announces Filing of Provision Patent for Polycystic Kidney Disease
• Increased Xanthine Oxidase Expression in ADPKD Kidneys • • Increased Xanthine Oxidase Expression in ADPKD Kidneys • ...
Cognition Therapeutics to Participate in Next-Generation Alzheimer’s Disease Panel at Virtual Biotech Showcase on January ...
Lisa Ricciardi, CEO, to participate as a Panelist in, “Aduhelm: Stimulating the Next- Generation of AD Treatment” Lisa Ricciardi, CEO, to participate as a Panelist in, “Aduhelm: Stimulating the Next- Generation of AD Treatment” ...
Ixtlan Bioscience Announces the Filing of New Patent for the Psilocybin Treatment of Alzheimer's Disease and Brain Pathologies
TEL AVIV, Israel, Dec. 21, 2021 /PRNewswire/ -- Ixtlan Bioscience, a biotech company focused on developing psilocybin-based treatment for Alzheimer's Disease and Brain Pathologies, has announced today the filing of a new Provisional Patent with the United
FDA approves first injectable treatment to prevent HIV infection
The US Food and Drug Administration (FDA) has approved an injectable form of GlaxoSmithKline’s (GSK) cabotegravir drug that is given every two months to prevent an HIV infection. The injection —
Help with the Great Healing in 2022 Become a Hypnotherapist
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Living with Huntington’s Disease Chorea
Sunnyside Daily Sun | 2021-12-21, 11:30
(BPT) - Before experiencing any symptoms, James McGann decided to get tested for Huntington's Disease (HD) in his mid-50s. Since his mother had HD, he knew that he had a 50% chance of developing the disorder, and he wanted to tell his children if they too were
Biogen halves price tag on Alzheimer's drug; annual cost still $28K
Kingsport Times-News | 2021-12-21, 11:28
Biogen is slashing the price of its Alzheimer’s treatment in half months after it debuted to widespread criticism for an initial cost that could reach $56,000 annually. The drugmaker said Monday that it will cut the wholesale acquisition cost of the drug by
Biogen cuts the price tag on its Alzheimer's drug in half
Biogen is slashing the price of its Alzheimer's treatment in half months after it debuted to widespread criticism for an initial cost that could reach $56,000 annually. The drugmaker said Monday that it will cut the wholesale acquisition cost of the drug by
One year into TRAILBLAZER study, Carl Fox believes more than ever he'll get rid of HIV
COVINGTON, Ky. — One of the things that kept Carl Fox going after he contracted HIV in 1985 was a promise that he made to himself. Fox vowed to survive, he said, so he could testify to what people with HIV and AIDS encountered back then. “When they try and
Be careful of diseases caused by contaminated floodwater
From DR KOH KAR CHAI, Malaysian Medical Association president Read full story ...
Update on Implementation of National Policy for Rare Diseases (Ministry of Health and Family Welfare of the Republic of India)
) Ministry of Health and Family Welfare Update on Implementation of National Policy for Rare Diseases Posted On: 21 DEC 2021 3:07PM by PIB Delhi In order to provide facilities for treatment and care of patients suffering from rare diseases,eight (08) Centres
New Alzheimer’s prevention trial in young people
Washington University School of Medicine in St. Louis is launching an international clinical trial aimed at preventing Alzheimer’s disease in people genetically destined to develop the illness at a young age. Unlike most other Alzheimer’s prevention trials,
