Phyllis Christine Cast (born 1960) is an American romance/fantasy author, known for the House of Night series she writes with her daughter Kristin Cast, as well as her own Goddess Summoning and Partholon book series.
On her own, P.C. Cast is known for her Goddess Summoning and Partholon book series. Her first book, Goddess by Mistake, was originally published in 2001, won the Prism, Holt Medallion, and Laurel Wreath awards, and was a finalist for the National Readers' Choice Award; her subsequent books have won a variety of prizes.
In 2005, she and her daughter began co-writing the House of Night series. In the wake of the current popularity of vampire fiction led by Stephenie Meyer's Twilight series, the Casts' books have enjoyed substantial and increasing critical and commercial success, and in March 2009, the fifth book in their series, Hunted, opened at number one on the best-seller lists of USA Today and The Wall Street Journal.
According to P.C. Cast, the concept for the House of Night novels came from her agent, who suggested the theme "vampire finishing school." The books take place in an alternative universe version of Tulsa, Oklahoma inhabited by both humans and "vampyres" (Cast uses this alternative spelling in the books, explaining it as a choice she made "just 'cause I like the way it looks"). The protagonist, Zoey Redbird, age 16, is "marked" as a "fledgling" and moves to the "House of Night" school to undergo her transformation.
PC or pc may refer to:
A modular connector is an electrical connector that was originally designed for use in telephone wiring, but has since been used for many other purposes. Many applications that originally used a bulkier, more expensive connector have converted to modular connectors. Probably the most well known applications of modular connectors are for telephone jacks and for Ethernet jacks, both of which are nearly always modular connectors.
Modular connectors were originally used in the Registration Interface system, mandated by the Federal Communications Commission (FCC) in 1976 in which they became known as registered jacks. The registered jack specifications define the wiring patterns of the jacks, not the physical dimensions or geometry of the connectors of either gender. Instead, these latter aspects are covered by ISO standard 8877, first used in ISDN systems. TIA/EIA-568 is a standard for data circuits wired on modular connectors.
Other systems exist for assigning signals to modular connectors; physical interchangeability of plugs and jacks does not ensure interoperation, nor protection from electrical damage to circuits. For example, modular cables and connectors have been used to supply low-voltage AC or DC power and no clear standard exists for this application.
P&C may refer to:
The first Pentium microprocessor was introduced by Intel on March 22, 1993. Dubbed P5, its microarchitecture was the fifth generation for Intel, and the first superscalar IA-32 microarchitecture. As a direct extension of the 80486 architecture, it included dual integer pipelines, a faster floating-point unit, wider data bus, separate code and data caches and features for further reduced address calculation latency. In 1996, the Pentium with MMX Technology (often simply referred to as Pentium MMX) was introduced with the same basic microarchitecture complemented with an MMX instruction set, larger caches, and some other enhancements.
The P5 Pentium competitors included the Motorola 68060 and the PowerPC 601 as well as the SPARC, MIPS, and Alpha microprocessor families, most of which also used a superscalar in-order dual instruction pipeline configuration at some time.
Intel's Larrabee multicore architecture project uses a processor core derived from a P5 core (P54C), augmented by multithreading, 64-bit instructions, and a 16-wide vector processing unit. Intel's low-powered Bonnell microarchitecture employed in Atom processor cores also uses an in-order dual pipeline similar to P5.
1-Pyrroline-5-carboxylic acid, also known as 1-pyrroline-5-carboxylate, delta-1-pyrroline-5-carboxylic acid, and P5C, is an imino acid. The stereoisomer (S)-1-pyrroline-5-carboxylate is a biosynthetic metabolite that is synthesized from proline by the enzyme pyrroline-5-carboxylate reductase and converted into the amino acid glutamate by the enzyme 1-pyrroline-5-carboxylate dehydrogenase.
Cytochrome P450, family 1, subfamily A, polypeptide 1 is a protein that in humans is encoded by the CYP1A1 gene. The protein is a member of the cytochrome P450 superfamily of enzymes.
CYP1A1 is involved in phase I xenobiotic and drug metabolism (one substrate of it is theophylline). It is inhibited by fluoroquinolones and macrolides and induced by aromatic hydrocarbons.
CYP1A1 is also known as AHH (aryl hydrocarbon hydroxylase). It is involved in the metabolic activation of aromatic hydrocarbons (polycyclic aromatic hydrocarbons, PAH), for example, benzo(a)pyrene (BP), by transforming it to an epoxide. In this reaction, the oxidation of benzo[a]pyrene is catalysed by CYP1A1 to form BP-7,8-epoxide, which can be further oxidized by epoxide hydrolase (EH) to form BP-7,8-dihydrodiol. Finally CYP1A1 catalyses this intermediate to form BP-7,8-dihydrodiol-9,10-epoxide, which is the ultimate carcinogen.
However, an in vivo experiment with gene-deficient mice has found that the hydroxylation of benzo(a)pyrene by CYP1A1 can have an overall protective effect on the DNA, rather than contributing to potentially carcinogenic DNA modifications. This effect is likely due to the fact that CYP1A1 is highly active in the intestinal mucosa, and thus inhibits infiltration of ingested benzo(a)pyrene carcinogen into the systemic circulation.
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