Toxic! was a British weekly comic book published by Apocalypse Ltd. A total of 31 issues were published from March 28-October 24, 1991.
Toxic! was the idea of Pat Mills, Kevin O'Neill, Mike McMahon, John Wagner and Alan Grant. The aim was to provide creators an outlet for their work to be published with them retaining the rights and control of their work. This was in contrast to 2000 AD, which Mills had also launched in 1977. Toxic! was to be the main rival of 2000 AD, and Toxic! would be in full colour throughout as opposed to 2000AD, which was still mainly published in black and white.
Toxic! was published by Apocalypse Ltd, an offshoot of Neptune Distribution based in South Wigston, Leicester. Neptune also owned Trident Comics which printed black and white comics by mainly new, unpublished creators.
The first title released by Apocalypse was a Marshal Law special titled Kingdom of the blind published in October 1990. This was followed by the first issue of Toxic! in March 1991. Toxic! was initially dominated by Mills (Mills had rejected two of John Wagner's proposals, Button Man and Al's Baby for not fitting in with his vision for the comic. These two strips later appeared in 2000 AD and the Judge Dredd Megazine respectively). His Marshal Law strip was seen as the flagship title and a character to perhaps rival Judge Dredd. Mills also wrote Accident Man (with Tony Skinner) and Muto-Maniac in the first issue, which was rounded out by a short strip by Alan Grant and Simon Bisley.
Toxicity is the degree to which a substance can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large.
A central concept of toxicology is that effects are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass animal testing, while maintaining the concept of toxicity endpoints.
There are generally three types of toxic entities; chemical, biological, and physical:
Toxic is the fifth studio album by Japanese rock band the Gazette. It was released on October 5, 2011 in Japan and includes four singles: "Shiver", "Red", "Pledge", and "Vortex". The album scored number 3 on the Oricon Daily Charts and number 6 on the Oricon Weekly Charts, selling 25,412 copies in its first week.
Complementary metal–oxide–semiconductor (CMOS) /ˈsiːmɒs/ is a technology for constructing integrated circuits. CMOS technology is used in microprocessors, microcontrollers, static RAM, and other digital logic circuits. CMOS technology is also used for several analog circuits such as image sensors (CMOS sensor), data converters, and highly integrated transceivers for many types of communication. In 1963, while working for Fairchild Semiconductor, Frank Wanlass patented CMOS (US patent 3,356,858).
CMOS is also sometimes referred to as complementary-symmetry metal–oxide–semiconductor (or COS-MOS). The words "complementary-symmetry" refer to the fact that the typical design style with CMOS uses complementary and symmetrical pairs of p-type and n-type metal oxide semiconductor field effect transistors (MOSFETs) for logic functions.
Two important characteristics of CMOS devices are high noise immunity and low static power consumption. Since one transistor of the pair is always off, the series combination draws significant power only momentarily during switching between on and off states. Consequently, CMOS devices do not produce as much waste heat as other forms of logic, for example transistor–transistor logic (TTL) or NMOS logic, which normally have some standing current even when not changing state. CMOS also allows a high density of logic functions on a chip. It was primarily for this reason that CMOS became the most used technology to be implemented in VLSI chips.
CMOS is a complementary metal–oxide–semiconductor, a class of integrated circuits.
CMOS may also refer to:
Nonvolatile BIOS memory refers to a small memory on PC motherboards that is used to store BIOS settings. It was traditionally called CMOS RAM because it used a volatile, low-power complementary metal-oxide-semiconductor (CMOS) SRAM (such as the Motorola MC146818 or similar) powered by a small battery when system power was off (called the CMOS battery).
The term remains in wide use but it has grown into a misnomer: nonvolatile storage in contemporary computers is often in EEPROM or flash memory (like the BIOS code itself); the remaining usage for the battery is then to keep the real-time clock (RTC) going. The typical NVRAM capacity is 512 bytes, which is generally sufficient for all BIOS settings. The CMOS RAM and the real-time clock have been integrated as a part of the southbridge chipset and it may not be a standalone chip on modern motherboards.
The memory battery (aka motherboard, CMOS, real-time clock (RTC), clock battery) is generally a CR2032 lithium coin cell. These cells last two to ten years, depending on the type of motherboard, ambient temperature and the length of time that the system is powered off, while other common cell types can last significantly longer or shorter periods, such as the CR2016 which will generally last about 40% less than CR2032. Higher temperatures and longer power-off time will shorten cell life. When replacing the cell, the system time and CMOS BIOS settings may revert to default values. This may be avoided by replacing the cell with the power supply master switch on. On ATX motherboards, this will supply 5V power to the motherboard even if it is apparently "switched off" and keep the CMOS memory energized.