This essay discusses the frontier borderlands of East Asia from the seventeenth through nineteenth century. I analyze Chinese dynastic political practice, its legacy on early twentieth and twenty-first century geopolitics, as well as the need for American progressive positioning regarding the Uyghurs. In my view, commentary on this issue needs to be firmly rooted in leftist opposition to international human rights abuses, (Pukr) while resisting Sinophobia, US militarism, and Cold War exaggeration and intervention. I highlight these borders by looking at multiple frontiers geographically and thematically. Generally speaking, the regions discussed are covered in terms of the following respective evolving institutional zones: (1) the northeast, Manchuria, eastern Mongolia and Chosŏn Korea, (2) the southwest, Yunnan, Tibet and India (3) the northwest, Turkestan and Xinjiang, and (4) the north, and Outer and Inner Mongolia. I will show how each area had its own set of social, political and economic implications of environmental territory and history “across forest, steppe and mountain.”[1] To understand the problematic nature of American imperialism and Frederick Jackson Turner’s “frontier thesis” is to understand China’s own borderlands and how Uyghurs today, or “people in the middle” get in the way of uncompromising nation-building. More