- published: 18 Apr 2012
- views: 7308
C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. This is the process by which T cells are attracted to specific tissue and organ targets. Many forms of HIV, the virus that causes AIDS, initially use CCR5 to enter and infect host cells. Certain individuals carry a mutation known as CCR5-Δ32 in the CCR5 gene, protecting them against these strains of HIV.
In humans, the CCR5 gene that encodes the CCR5 protein is located on the short (p) arm at position 21 on chromosome 3. Certain populations have inherited the Delta 32 mutation resulting in the genetic deletion of a portion of the CCR5 gene. Homozygous carriers of this mutation are resistant to M-tropic strains of HIV-1 infection.
The CCR5 protein belongs to the beta chemokine receptors family of integral membrane proteins. It is a G protein–coupled receptor which functions as a chemokine receptor in the CC chemokine group.
Questions asked during CAN GENE THERAPY CURE HIV?, our community forum with Nobel laureate David Baltimore and stem cell expert Paula Cannon. Hosted by Paris Mullen for the defeatHIV Community Advisory Board on August 12, 2015 at Fred Hutch.
http://sevens.exposed/ Do the genes on the pages tell us the story of what happened really in america? does it also tell us about how the cure for HIV has been hidden and locked away for the people that can "afford" it? https://en.wikipedia.org/wiki/CCR5 http://genetics.thetech.org/original_news/news13 https://www.google.com/url?sa=t&rct;=j&q;=&esrc;=s&source;=web&cd;=8&ved;=0ahUKEwiM3rjU4ZvTAhXJrVQKHQeuCAQQFgg1MAc&url;=https%3A%2F%2Fwww.newscientist.com%2Farticle%2Fmg22129562-100-ancestry-of-first-americans-revealed-by-a-boys-genome%2F&usg;=AFQjCNHPwZ9PSwBg85qXCgSHU4kzh2Du5Q&sig2;=yjTB2hWEFhJOeBHdJNjsTQ&bvm;=bv.152180690,d.cGw&cad;=rja
This is my entry for the Congress of Future Medical Leaders Medical School Scholarship Challenge. It covers the background of HIV infection and spread, as well as the CCR5-∆32 mutation. Also in the video is my proposal for a possible HIV/AIDS vaccine using the CCR5-∆32 mutation. futuredocsnow http://www.futuredocs.com
Video by Zachary Goldsmith, Univ. of Pennsylvania '14 For CHEM 251: Biochemistry, Spring 2014, Professor Jeffery Saven Brief introduction to the role of CCR5 in HIV binding and immune response followed by the biochemical discussion of Maraviroc inhibition of CCR5 from Tan et al. (2013) Science 341
This video features my analysis of the theory that the CCR5 - Delta32 DNA Gene mutation is responsible for gang-stalking, community harassment and covert electronic torture. The following video link features an interview with Cynthia Brewer who claims to be an experimentee because of her possession of the Delta32 mutation; https://www.youtube.com/watch?v=cHRr9lcR8Ys She mentions the following patent on the issue in her interview (#4237224) http://patents.com/us-4237224.html;
Hora ashimoto wo mite goran
Kore ga anata no ayumu michi
Hora mae wo mite goran
Are ga anata no mirai
Haha ga kureta takusan no yasashisa
Ai wo idaite ayumeto kurikaeshita
Ano toki wa mada osanakute imi nado shiranai
Donna watashi no te wo nigiri
Isshoni ayundekita
Yume wa itsumo sora takaku aru kara
Todokanakute kowai ne dakedo oitsuzukeru no
Jibun no sutori dakara koso akirametakunai
Fuan ni naruto te wo nigiri
Isshoni ayundekita
Sono yasashisa wo toki ni wa iyagari
Hanareta haha e sunao ni narezu
Hora ashimoto wo mite goran
Kore ga anata no ayumu michi
Hora mae wo mite goran
Are ga anata no mirai
Sono yasashisa wo toki ni wa iyagari
Hanareta haha e sunao ni narezu
Hora ashimoto wo mite goran
Kore ga anata no ayumu michi
Hora mae wo mite goran
Are ga anata no mirai
Hora ashimoto wo mite goran
Kore ga anata no ayumu michi
Hora mae wo mite goran
Are ga anata no mirai
Mirai e mukatte