- published: 19 Sep 2015
- views: 24167
Macrophages (Greek: big eaters, from Greek μακρος (makros) = large, φαγειν (phagein) = to eat) are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the types of proteins specific to the surface of healthy body cells on its surface in a process called phagocytosis. These large phagocytes are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune cells such as lymphocytes. For example, they are important as antigen presenters to T cells. In humans, dysfunctional macrophages cause severe diseases such as chronic granulomatous disease that result in frequent infections.
Beyond increasing inflammation and stimulating the immune system, macrophages also play an important anti-inflammatory role and can decrease immune reactions through the release of cytokines. Macrophages that encourage inflammation are called M1 macrophages, whereas those that decrease inflammation and encourage tissue repair are called M2 macrophages. This difference is reflected in their metabolism; M1 macrophages have the unique ability to metabolize arginine to the "killer" molecule nitric oxide, whereas M2 macrophages have the unique ability to metabolize arginine to the "repair" molecule ornithine.
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A short film about macrophages. These are specialized cells that patrol the body to protect it against invading bacteria and other pathogens. When they find they swallow & digest them. The action takes place amongst the villi of the bowel. The environments were modelled in Zbrush, whilst the animation and rendering were done in Modo. Compositing took place in Hitfilm 3 Pro and Fusion 7.
What is Sansamed? We at Sansamed know that medicine can be difficult at times, understanding basic medical concepts and processes can be very frustrating which brings us to our main goal which will be to produce videos that hopefully would make medicine simpler and more fun to understand. What is the immune system: The immune system is an organisms defense mechanism against pathogens (disease inducing microorganisms such as virus, bacteria, fungi, parasites, prions). Our immune system is divided into 2 major parts: innate and adaptive in which we have multiple cells and proteins that constantly works with neutralizing and removing countless pathogens that attack us on daily basis. What are the functions of macrophages? Macrophages are multifunctional cells. The functions include; APC (...
Macrophage, a central player in inflammation, innate and acquired immunity.
Human macrophage cell line engulfing red blood cells from sheep. Video by Dr. Richard Tsai.
http://www.cincinnatichildrens.org/hlh Meet Max, and learn about the rare immune disorder called hemophagocytic lymphohistiocytosis, better known as HLH. In patients with HLH, the immune system does not work as it should, and often requires a bone marrow transplant. Cincinnati Children’s is one of the most experienced facilities in the nation in treating HLH and the clinical and research pioneers at Cincinnati Children’s HLH Center of Excellence are committed to changing the outcome for children who have it. Credits: Medialab at Cincinnati Children's Animation: Jeff Cimprich and Ren Wilkey Medialab Direction and additional content expertise: Ken Tegtmeyer, MD Content Experts: Stella Davies, MBBS, Ashish Kumar, MD Additional Production Work: Julie Daisey Voiceover: Emma Perentesis 2D Ar...
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Difference between monocyte and macrophage romance youtube . , . . . . Difference between monocyte and macrophage . Monocyte vs differencebetween difference between monocyte and macrophage a class "_zkb" href " url?q webcache.Googleusercontent search. Here are some more compilation of topics and latest discussions relates to this video, which we found thorough the internet. Hope this information will helpful to get idea in brief about this. Monocyte vs macrophage the immune system is composed of few types of cells including lymphocytes, macrophages, monocytes, neutrophils, best answer when the cell is in blood it is called monocyte and when it enters tissues it becomes macrophages. There are also some other below information will help you to get some more though about the subje...
Macrophage, a central player in inflammation, innate and acquired immunity.