National Institutes of Health

The National Institutes of Health (NIH) is a biomedical research facility primarily located in Bethesda, Maryland. An agency of the United States Department of Health and Human Services, it is the primary agency of the United States government responsible for biomedical and health-related research. The NIH both conducts its own scientific research through its Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program.

With 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, the IRP is the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical research funding spent annually in the U.S., or about US$26.4 billion.

The NIH comprises 27 separate institutes and centers that conduct research in different disciplines of biomedical science. The IRP is responsible for many scientific accomplishments, including the discovery of fluoride to prevent tooth decay, the use of lithium to manage bipolar disorder, and the creation of vaccines against hepatitis, Haemophilus influenzae (HIB) and human papillomavirus (HPV).

Clash Royale

Clash Royale is a 2016 freemium mobile strategy video game developed and published by Supercell, a video game company based in Helsinki, Finland. The game was soft-launched in Canada, Hong Kong, Australia, Sweden, Norway, Denmark, Iceland, Finland and New Zealand for iOS platforms on January 4, 2016. More countries will be added in the near future as Supercell receives feedback about the game. The date for the game's release globally and on the Android platform is March 2016.

Gameplay

Clash Royale is a real-time strategy game where players collect and upgrade different cards that are based on characters from the Clash of Clans universe. Each card is unique, and you can only have 8 in a non deck at a time. They are used with the goal of destroying your opponent's towers. Victories lead to more cards, trophies and glory. Players can unlock new arenas, challenge other players online, and form clans to share cards and participate in private duels.

Chests

There are three main types of chests in Clash Royale. You get a free chest every four hours, but you can only store two of these at a time. They must be collected to activate the countdown timer for your next free chest. Crown chests are available every 24 hours. Crown chests offer free loot, cards and sometimes gems. To unlock them, you must earn 10 crowns in multiplayer battles. The final type of chests, treasure chests, come in three varieties: the silver chest, gold chest, and magical chest. These chests will be given to you whenever you win a battle (given that you have free chest slots available) and they can also be purchased using gems.

National Institutes of Health Stroke Scale

The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS) is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke. The NIHSS is composed of 11 items, each of which scores a specific ability between a 0 and 4. For each item, a score of 0 typically indicates normal function in that specific ability, while a higher score is indicative of some level of impairment. The individual scores from each item are summed in order to calculate a patient's total NIHSS score. The maximum possible score is 42, with the minimum score being a 0.

Performing the scale

Throughout the NIHSS it is important that the examiner does not coach or help with the assigned task. The examiner may demonstrate the commands to patients that are unable to comprehend verbal instructions, however the score should reflect the patient's own ability. It is acceptable for the examiner to physically help the patient get into position to begin the test, but the examiner must not provide further assistance while the patient is attempting to complete the task. For each item the examiner should score the patient's first effort, and repeated attempts should not affect the patient's score. An exception to this rule exist in the language assessment (Item 9) in which the patient's best effort should be scored. Some of the items contain "Default Coma Scores", these scores are automatically assigned to patients that scored a 3 in item 1a.