Brian Ferentz (born March 28, 1983 in Iowa City, Iowa) is an American football offensive line coach for the University of Iowa and a former offensive lineman in the National Football League.

Ferentz played football as an offensive lineman for his father, Iowa head coach Kirk Ferentz, from 2001 through 2005. After going undrafted in the 2006 NFL Draft, Ferentz signed a free agent contract with the Atlanta Falcons in May 2006. He was released by the Falcons on September 2, 2006, and spent the season on the Falcons' practice squad. He was waived by the Falcons on May 14, 2007 and signed by the New Orleans Saints on August 13, 2007, only to be released by the Saints on September 1, 2007.

Ferentz joined the New England Patriots in 2008 as a scouting assistant; his father Kirk was a former assistant coach under Patriots head coach Bill Belichick when Belichick coached the Cleveland Browns in the 1990s. In 2009, Ferentz became an offensive coaching assistant. Before the 2010 season, Ferentz's title was changed to offensive assistant coach, working primarily with the Patriots' tight ends. He was officially promoted to tight ends coach in 2011; that season, the Patriots' tight end duo of Aaron Hernandez and Rob Gronkowski set NFL records for receptions, yards, and touchdowns by tight ends, and Gronkowski became the first tight end in NFL history to lead the league in touchdown receptions.