- published: 19 Feb 2010
- views: 573738
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Review of B cells, CD4+ T cells and CD8+ T cells
More free lessons at: http://www.khanacademy.org/video?v=xaz5ftvZCyI
Introduction to helper T cells and their role in activating B cells
More free lessons at: http://www.khanacademy.org/video?v=uwMYpTYsNZM
- published: 19 Feb 2010
- views: 669786
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study materials here-
http://shomusbiology.weebly.com/bio-materials.html
Source of the article published in description is Wikipedia. Thanks to original content developers.
Link- http://en.wikipedia.org/wiki/Main_Page
T cells or T lymphocytes are a type of lymphocyte (itself a type of white blood cell) that play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They do not have antigen-presenting properties (but rather, requiring B cells or NK cells for its antigen-presenting property). They are called T cells because they mature in the thymus.[1] There are several subsets of T cells, each with a distinct function.
Activation of CD4+ T cells occurs through the simultaneous engagement of the T cell receptor and a costimulatory molecule (like CD28, or ICOS) on the T cell by the major histocompatibility complex (MHCII) peptide and costimulatory molecules on the APC. Both are required for production of an effective immune response; in the absence of co-stimulation, T-cell receptor signalling alone results in anergy. The signalling pathways downstream from costimulatory molecules usually engages the PI3K pathway generating PIP3 at the plasma membrane and recruiting PH domain containing signaling molecules like, PDK1 that are essential for the activation of PKCtheta, and eventual IL-2 production.
The first signal is provided by binding of the T cell receptor its cognate peptide presented on MHCII on an antigen presenting cell. MHCII is restricted to so called professional antigen presenting cells, like dendritic cells, B cells and macrophages to name a few. The peptides presented to CD8+ T cells by MHC class I molecules are 8--9 amino acids in length; the peptides presented to CD4+ cells by MHC class II molecules are longer, usually 12--25 amino acids in length,[11] as the ends of the binding cleft of the MHC class II molecule are open.
The second signal comes from co-stimulation, in which surface receptors on the APC are induced by a relatively small number of stimuli, usually products of pathogens, but sometimes breakdown products of cells, such as necrotic-bodies or heat shock proteins. The only co-stimulatory receptor expressed constitutively by naïve T cells is CD28, so co-stimulation for these cells comes from the CD80 and CD86 proteins, which together constitute the B7 protein, (B7.1 and B7.2 respectively) on the APC. Other receptors are expressed upon activation of the T cell, such as OX40 and ICOS, but these largely depend upon CD28 for their expression. The second signal licenses the T cell to respond to an antigen. Without it, the T cell becomes anergic, and it becomes more difficult for it to activate in future. This mechanism prevents inappropriate responses to self, as self-peptides will not usually be presented with suitable co-stimulation.
- published: 20 Nov 2013
- views: 12139
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, from stem cells right through to their mature helper and cytotoxic forms. This video also looks at some of the cell markers used for differentiation. For more entirely FREE tutorials and the accompanying PDFs visit http://www.handwrittentutorials.com
- published: 21 Aug 2012
- views: 80104
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T cell "braking."This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
- published: 12 Feb 2013
- views: 103121
Cambridge University's Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. Check out the rest of the series here: http://bit.ly/A6bwCE
In this video we see a killer T cell of the immune system attacking a cancer cell.
Professor Gillian Griffiths:
"Cells of the immune system protect the body against pathogens. If cells in our bodies are infected by viruses, or become cancerous, then killer cells of the immune system identify and destroy the affected cells. Cytotoxic T cells are very precise and efficient killers. They are able to destroy infected or cancerous cells, without destroying healthy cells surrounding them. The Wellcome Trust funded laboratory of Professor Gillian Griffiths, at the Cambridge Institute for Medical Research, investigates just how this is accomplished. By understanding how this works, we can develop ways to control killer cells. This will allow us to find ways to improve cancer therapies, and ameliorate autoimmune diseases caused when killer cells run amok and attack healthy cells in our bodies."
Cytotoxic T cells are just 10 microns in length: approximately one-tenth the width of a human hair. These movies are 92 times real time.
The original footage shown was made by Alex Ritter, a PhD student on the NIH-OxCam programme, in the laboratory of Professor Gillian Griffiths at the Cambridge Institute for Medical Research and the Department of Medicine of the Clinical School of the University of Cambridge. The images were acquired using an Andor Revolution spinning disk system with an Olympus microscope. Professor Griffiths is a Wellcome Trust Principal Research Fellow.
Links for more information:
http://www.cimr.cam.ac.uk
http://www.cimr.cam.ac.uk/investigators/griffiths/index.html
http://www.immunology.cam.ac.uk/about
Music by Intercontinental Music Lab
http://www.intercontinentalmusiclab.com
Find more Cambridge University research here:
http://www.cam.ac.uk/research
- published: 03 Feb 2012
- views: 1070131
T cell
T cells (also known as Thymocytes cells) or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.
Types
Helper
T helper cells (TH cells) assist other white blood cells in immunologic processes, including maturation of B cells into plasma cells and memory B cells, and activation of cytotoxic T cells and macrophages. These cells are also known as CD4+ T cells because they express the CD4 glycoprotein on their surfaces. Helper T cells become activated when they are presented with peptide antigens by MHC class II molecules, which are expressed on the surface of antigen-presenting cells (APCs). Once activated, they divide rapidly and secrete small proteins called cytokines that regulate or assist in the active immune response. These cells can differentiate into one of several subtypes, including TH1, TH2, TH3, TH17, Th9, or TFH, which secrete different cytokines to facilitate different types of immune responses. Signalling from the APC directs T cells into particular subtypes.
This page contains text from Wikipedia, the Free Encyclopedia -
https://wn.com/T_cell
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
Cell
Cell(s) may refer to:
Science and technology
- Cell, area of radio coverage in a cellular network
- Galvanic cell or Voltaic cell, a particular kind of electrochemical cell
This page contains text from Wikipedia, the Free Encyclopedia -
https://wn.com/Cell
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
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11:07Review of B cells, CD4+ T cells and CD8+ T cells
Review of B cells, CD4+ T cells and CD8+ T cellsReview of B cells, CD4+ T cells and CD8+ T cells
Review of B cells, CD4+ T cells and CD8+ T cells More free lessons at: http://www.khanacademy.org/video?v=xaz5ftvZCyI -
20:34Helper T Cells
Helper T CellsHelper T Cells
Introduction to helper T cells and their role in activating B cells More free lessons at: http://www.khanacademy.org/video?v=uwMYpTYsNZM -
3:38T-Cell Activation
T-Cell ActivationT-Cell Activation
-
6:56Immunology Map III - T cell development I
Immunology Map III - T cell development I -
1:55Killer T Cell: The Cancer Assassin
Killer T Cell: The Cancer Assassin -
32:37T cell development
T cell developmentT cell development
For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Source of the article published in description is Wikipedia. Thanks to original content developers. Link- http://en.wikipedia.org/wiki/Main_Page T cells or T lymphocytes are a type of lymphocyte (itself a type of white blood cell) that play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They do not have antigen-presenting properties (but rather, requiring B cells or NK cells for its antigen-presenting property). They are called T cells because they mature in the thymus.[1] There are several subsets of T cells, each with a distinct function. Activation of CD4+ T cells occurs through the simultaneous engagement of the T cell receptor and a costimulatory molecule (like CD28, or ICOS) on the T cell by the major histocompatibility complex (MHCII) peptide and costimulatory molecules on the APC. Both are required for production of an effective immune response; in the absence of co-stimulation, T-cell receptor signalling alone results in anergy. The signalling pathways downstream from costimulatory molecules usually engages the PI3K pathway generating PIP3 at the plasma membrane and recruiting PH domain containing signaling molecules like, PDK1 that are essential for the activation of PKCtheta, and eventual IL-2 production. The first signal is provided by binding of the T cell receptor its cognate peptide presented on MHCII on an antigen presenting cell. MHCII is restricted to so called professional antigen presenting cells, like dendritic cells, B cells and macrophages to name a few. The peptides presented to CD8+ T cells by MHC class I molecules are 8--9 amino acids in length; the peptides presented to CD4+ cells by MHC class II molecules are longer, usually 12--25 amino acids in length,[11] as the ends of the binding cleft of the MHC class II molecule are open. The second signal comes from co-stimulation, in which surface receptors on the APC are induced by a relatively small number of stimuli, usually products of pathogens, but sometimes breakdown products of cells, such as necrotic-bodies or heat shock proteins. The only co-stimulatory receptor expressed constitutively by naïve T cells is CD28, so co-stimulation for these cells comes from the CD80 and CD86 proteins, which together constitute the B7 protein, (B7.1 and B7.2 respectively) on the APC. Other receptors are expressed upon activation of the T cell, such as OX40 and ICOS, but these largely depend upon CD28 for their expression. The second signal licenses the T cell to respond to an antigen. Without it, the T cell becomes anergic, and it becomes more difficult for it to activate in future. This mechanism prevents inappropriate responses to self, as self-peptides will not usually be presented with suitable co-stimulation. -
10:00T Cell Development
T Cell DevelopmentT Cell Development
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, from stem cells right through to their mature helper and cytotoxic forms. This video also looks at some of the cell markers used for differentiation. For more entirely FREE tutorials and the accompanying PDFs visit http://www.handwrittentutorials.com -
26:36T Cell Activation and Control
T Cell Activation and ControlT Cell Activation and Control
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T cell "braking."This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology. To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology. -
10:07Cytotoxic T Cells
Cytotoxic T Cells -
1:02Killer T cell attacking cancer
Killer T cell attacking cancerKiller T cell attacking cancer
Cambridge University's Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. Check out the rest of the series here: http://bit.ly/A6bwCE In this video we see a killer T cell of the immune system attacking a cancer cell. Professor Gillian Griffiths: "Cells of the immune system protect the body against pathogens. If cells in our bodies are infected by viruses, or become cancerous, then killer cells of the immune system identify and destroy the affected cells. Cytotoxic T cells are very precise and efficient killers. They are able to destroy infected or cancerous cells, without destroying healthy cells surrounding them. The Wellcome Trust funded laboratory of Professor Gillian Griffiths, at the Cambridge Institute for Medical Research, investigates just how this is accomplished. By understanding how this works, we can develop ways to control killer cells. This will allow us to find ways to improve cancer therapies, and ameliorate autoimmune diseases caused when killer cells run amok and attack healthy cells in our bodies." Cytotoxic T cells are just 10 microns in length: approximately one-tenth the width of a human hair. These movies are 92 times real time. The original footage shown was made by Alex Ritter, a PhD student on the NIH-OxCam programme, in the laboratory of Professor Gillian Griffiths at the Cambridge Institute for Medical Research and the Department of Medicine of the Clinical School of the University of Cambridge. The images were acquired using an Andor Revolution spinning disk system with an Olympus microscope. Professor Griffiths is a Wellcome Trust Principal Research Fellow. Links for more information: http://www.cimr.cam.ac.uk http://www.cimr.cam.ac.uk/investigators/griffiths/index.html http://www.immunology.cam.ac.uk/about Music by Intercontinental Music Lab http://www.intercontinentalmusiclab.com Find more Cambridge University research here: http://www.cam.ac.uk/research
-
Review of B cells, CD4+ T cells and CD8+ T cells
Review of B cells, CD4+ T cells and CD8+ T cells More free lessons at: http://www.khanacademy.org/video?v=xaz5ftvZCyI
published: 19 Feb 2010 -
Helper T Cells
Introduction to helper T cells and their role in activating B cells More free lessons at: http://www.khanacademy.org/video?v=uwMYpTYsNZM
published: 19 Feb 2010 -
T-Cell Activation
published: 02 Jan 2014 -
-
-
T cell development
For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Source of the article published in description is Wikipedia. Thanks to original content developers. Link- http://en.wikipedia.org/wiki/Main_Page T cells or T lymphocytes are a type of lymphocyte (itself a type of white blood cell) that play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They do not have antigen-presenting properties (but rather, requiring B cells or NK cells for its antigen-presenting property). They are called T cells because they mature in the thymus.[1] The...
published: 20 Nov 2013 -
T Cell Development
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, from stem cells right through to their mature helper and cytotoxic forms. This video also looks at some of the cell markers used for differentiation. For more entirely FREE tutorials and the accompanying PDFs visit http://www.handwrittentutorials.com
published: 21 Aug 2012 -
T Cell Activation and Control
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T cell "braking."This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology. To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
published: 12 Feb 2013 -
-
Killer T cell attacking cancer
Cambridge University's Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. Check out the rest of the series here: http://bit.ly/A6bwCE In this video we see a killer T cell of the immune system attacking a cancer cell. Professor Gillian Griffiths: "Cells of the immune system protect the body against pathogens. If cells in our bodies are infected by viruses, or become cancerous, then killer cells of the immune system identify and destroy the affected cells. Cytotoxic T cells are very precise and efficient killers. They are able to destroy infected or cancerous cells, without destroying healthy cells surrounding them. The Wellcome Trust funded laboratory of Professor Gillian Griffiths, at the Cambridge Institute for Medic...
published: 03 Feb 2012
Review of B cells, CD4+ T cells and CD8+ T cells
- Order: Reorder
- Duration: 11:07
- Updated: 19 Feb 2010
- views: 573738
Review of B cells, CD4+ T cells and CD8+ T cells
More free lessons at: http://www.khanacademy.org/video?v=xaz5ftvZCyI
Review of B cells, CD4+ T cells and CD8+ T cells
More free lessons at: http://www.khanacademy.org/video?v=xaz5ftvZCyI
wn.com/Review Of B Cells, Cd4 T Cells And Cd8 T Cells
Review of B cells, CD4+ T cells and CD8+ T cells
More free lessons at: http://www.khanacademy.org/video?v=xaz5ftvZCyI
- published: 19 Feb 2010
- views: 573738
Helper T Cells
- Order: Reorder
- Duration: 20:34
- Updated: 19 Feb 2010
- views: 669786
Introduction to helper T cells and their role in activating B cells
More free lessons at: http://www.khanacademy.org/video?v=uwMYpTYsNZM
Introduction to helper T cells and their role in activating B cells
More free lessons at: http://www.khanacademy.org/video?v=uwMYpTYsNZM
wn.com/Helper T Cells
Introduction to helper T cells and their role in activating B cells
More free lessons at: http://www.khanacademy.org/video?v=uwMYpTYsNZM
- published: 19 Feb 2010
- views: 669786
T-Cell Activation
- Order: Reorder
- Duration: 3:38
- Updated: 02 Jan 2014
- views: 40053
- published: 02 Jan 2014
- views: 40053
Immunology Map III - T cell development I
- Order: Reorder
- Duration: 6:56
- Updated: 20 Jan 2013
- views: 106614
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wn.com/Immunology Map Iii T Cell Development I
Killer T Cell: The Cancer Assassin
- Order: Reorder
- Duration: 1:55
- Updated: 19 May 2015
- views: 567740
How does a Killer T Cell Kill its target?
Our new film captures the behaviour of cytotoxic T cells – the body’s ‘serial killers’ – as they hunt down and elimin...
How does a Killer T Cell Kill its target?
Our new film captures the behaviour of cytotoxic T cells – the body’s ‘serial killers’ – as they hunt down and eliminate cancer cells before moving on to their next target.
wn.com/Killer T Cell The Cancer Assassin
T cell development
- Order: Reorder
- Duration: 32:37
- Updated: 20 Nov 2013
- views: 12139
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study materials here-
http://shomusbiology.weebly.com/bio-materials.html
Source o...
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study materials here-
http://shomusbiology.weebly.com/bio-materials.html
Source of the article published in description is Wikipedia. Thanks to original content developers.
Link- http://en.wikipedia.org/wiki/Main_Page
T cells or T lymphocytes are a type of lymphocyte (itself a type of white blood cell) that play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They do not have antigen-presenting properties (but rather, requiring B cells or NK cells for its antigen-presenting property). They are called T cells because they mature in the thymus.[1] There are several subsets of T cells, each with a distinct function.
Activation of CD4+ T cells occurs through the simultaneous engagement of the T cell receptor and a costimulatory molecule (like CD28, or ICOS) on the T cell by the major histocompatibility complex (MHCII) peptide and costimulatory molecules on the APC. Both are required for production of an effective immune response; in the absence of co-stimulation, T-cell receptor signalling alone results in anergy. The signalling pathways downstream from costimulatory molecules usually engages the PI3K pathway generating PIP3 at the plasma membrane and recruiting PH domain containing signaling molecules like, PDK1 that are essential for the activation of PKCtheta, and eventual IL-2 production.
The first signal is provided by binding of the T cell receptor its cognate peptide presented on MHCII on an antigen presenting cell. MHCII is restricted to so called professional antigen presenting cells, like dendritic cells, B cells and macrophages to name a few. The peptides presented to CD8+ T cells by MHC class I molecules are 8--9 amino acids in length; the peptides presented to CD4+ cells by MHC class II molecules are longer, usually 12--25 amino acids in length,[11] as the ends of the binding cleft of the MHC class II molecule are open.
The second signal comes from co-stimulation, in which surface receptors on the APC are induced by a relatively small number of stimuli, usually products of pathogens, but sometimes breakdown products of cells, such as necrotic-bodies or heat shock proteins. The only co-stimulatory receptor expressed constitutively by naïve T cells is CD28, so co-stimulation for these cells comes from the CD80 and CD86 proteins, which together constitute the B7 protein, (B7.1 and B7.2 respectively) on the APC. Other receptors are expressed upon activation of the T cell, such as OX40 and ICOS, but these largely depend upon CD28 for their expression. The second signal licenses the T cell to respond to an antigen. Without it, the T cell becomes anergic, and it becomes more difficult for it to activate in future. This mechanism prevents inappropriate responses to self, as self-peptides will not usually be presented with suitable co-stimulation.
wn.com/T Cell Development
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study materials here-
http://shomusbiology.weebly.com/bio-materials.html
Source of the article published in description is Wikipedia. Thanks to original content developers.
Link- http://en.wikipedia.org/wiki/Main_Page
T cells or T lymphocytes are a type of lymphocyte (itself a type of white blood cell) that play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They do not have antigen-presenting properties (but rather, requiring B cells or NK cells for its antigen-presenting property). They are called T cells because they mature in the thymus.[1] There are several subsets of T cells, each with a distinct function.
Activation of CD4+ T cells occurs through the simultaneous engagement of the T cell receptor and a costimulatory molecule (like CD28, or ICOS) on the T cell by the major histocompatibility complex (MHCII) peptide and costimulatory molecules on the APC. Both are required for production of an effective immune response; in the absence of co-stimulation, T-cell receptor signalling alone results in anergy. The signalling pathways downstream from costimulatory molecules usually engages the PI3K pathway generating PIP3 at the plasma membrane and recruiting PH domain containing signaling molecules like, PDK1 that are essential for the activation of PKCtheta, and eventual IL-2 production.
The first signal is provided by binding of the T cell receptor its cognate peptide presented on MHCII on an antigen presenting cell. MHCII is restricted to so called professional antigen presenting cells, like dendritic cells, B cells and macrophages to name a few. The peptides presented to CD8+ T cells by MHC class I molecules are 8--9 amino acids in length; the peptides presented to CD4+ cells by MHC class II molecules are longer, usually 12--25 amino acids in length,[11] as the ends of the binding cleft of the MHC class II molecule are open.
The second signal comes from co-stimulation, in which surface receptors on the APC are induced by a relatively small number of stimuli, usually products of pathogens, but sometimes breakdown products of cells, such as necrotic-bodies or heat shock proteins. The only co-stimulatory receptor expressed constitutively by naïve T cells is CD28, so co-stimulation for these cells comes from the CD80 and CD86 proteins, which together constitute the B7 protein, (B7.1 and B7.2 respectively) on the APC. Other receptors are expressed upon activation of the T cell, such as OX40 and ICOS, but these largely depend upon CD28 for their expression. The second signal licenses the T cell to respond to an antigen. Without it, the T cell becomes anergic, and it becomes more difficult for it to activate in future. This mechanism prevents inappropriate responses to self, as self-peptides will not usually be presented with suitable co-stimulation.
- published: 20 Nov 2013
- views: 12139
T Cell Development
- Order: Reorder
- Duration: 10:00
- Updated: 21 Aug 2012
- views: 80104
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, from stem cells right through to their mature helper and cytotoxic form...
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, from stem cells right through to their mature helper and cytotoxic forms. This video also looks at some of the cell markers used for differentiation. For more entirely FREE tutorials and the accompanying PDFs visit http://www.handwrittentutorials.com
wn.com/T Cell Development
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, from stem cells right through to their mature helper and cytotoxic forms. This video also looks at some of the cell markers used for differentiation. For more entirely FREE tutorials and the accompanying PDFs visit http://www.handwrittentutorials.com
- published: 21 Aug 2012
- views: 80104
T Cell Activation and Control
- Order: Reorder
- Duration: 26:36
- Updated: 12 Feb 2013
- views: 103121
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T cell "braking."This webcast is part of an interactive online series de...
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T cell "braking."This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
wn.com/T Cell Activation And Control
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T cell "braking."This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
- published: 12 Feb 2013
- views: 103121
Cytotoxic T Cells
- Order: Reorder
- Duration: 10:07
- Updated: 19 Feb 2010
- views: 346674
How cytotoxic T cells get activated by MHC-I/antigen complexes and then proceed to kill infected cells
More free lessons at: http://www.khanacademy.org/video?v=...
How cytotoxic T cells get activated by MHC-I/antigen complexes and then proceed to kill infected cells
More free lessons at: http://www.khanacademy.org/video?v=oqI4skjr6lQ
wn.com/Cytotoxic T Cells
Killer T cell attacking cancer
- Order: Reorder
- Duration: 1:02
- Updated: 03 Feb 2012
- views: 1070131
Cambridge University's Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. Check out the r...
Cambridge University's Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. Check out the rest of the series here: http://bit.ly/A6bwCE
In this video we see a killer T cell of the immune system attacking a cancer cell.
Professor Gillian Griffiths:
"Cells of the immune system protect the body against pathogens. If cells in our bodies are infected by viruses, or become cancerous, then killer cells of the immune system identify and destroy the affected cells. Cytotoxic T cells are very precise and efficient killers. They are able to destroy infected or cancerous cells, without destroying healthy cells surrounding them. The Wellcome Trust funded laboratory of Professor Gillian Griffiths, at the Cambridge Institute for Medical Research, investigates just how this is accomplished. By understanding how this works, we can develop ways to control killer cells. This will allow us to find ways to improve cancer therapies, and ameliorate autoimmune diseases caused when killer cells run amok and attack healthy cells in our bodies."
Cytotoxic T cells are just 10 microns in length: approximately one-tenth the width of a human hair. These movies are 92 times real time.
The original footage shown was made by Alex Ritter, a PhD student on the NIH-OxCam programme, in the laboratory of Professor Gillian Griffiths at the Cambridge Institute for Medical Research and the Department of Medicine of the Clinical School of the University of Cambridge. The images were acquired using an Andor Revolution spinning disk system with an Olympus microscope. Professor Griffiths is a Wellcome Trust Principal Research Fellow.
Links for more information:
http://www.cimr.cam.ac.uk
http://www.cimr.cam.ac.uk/investigators/griffiths/index.html
http://www.immunology.cam.ac.uk/about
Music by Intercontinental Music Lab
http://www.intercontinentalmusiclab.com
Find more Cambridge University research here:
http://www.cam.ac.uk/research
wn.com/Killer T Cell Attacking Cancer
Cambridge University's Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. Check out the rest of the series here: http://bit.ly/A6bwCE
In this video we see a killer T cell of the immune system attacking a cancer cell.
Professor Gillian Griffiths:
"Cells of the immune system protect the body against pathogens. If cells in our bodies are infected by viruses, or become cancerous, then killer cells of the immune system identify and destroy the affected cells. Cytotoxic T cells are very precise and efficient killers. They are able to destroy infected or cancerous cells, without destroying healthy cells surrounding them. The Wellcome Trust funded laboratory of Professor Gillian Griffiths, at the Cambridge Institute for Medical Research, investigates just how this is accomplished. By understanding how this works, we can develop ways to control killer cells. This will allow us to find ways to improve cancer therapies, and ameliorate autoimmune diseases caused when killer cells run amok and attack healthy cells in our bodies."
Cytotoxic T cells are just 10 microns in length: approximately one-tenth the width of a human hair. These movies are 92 times real time.
The original footage shown was made by Alex Ritter, a PhD student on the NIH-OxCam programme, in the laboratory of Professor Gillian Griffiths at the Cambridge Institute for Medical Research and the Department of Medicine of the Clinical School of the University of Cambridge. The images were acquired using an Andor Revolution spinning disk system with an Olympus microscope. Professor Griffiths is a Wellcome Trust Principal Research Fellow.
Links for more information:
http://www.cimr.cam.ac.uk
http://www.cimr.cam.ac.uk/investigators/griffiths/index.html
http://www.immunology.cam.ac.uk/about
Music by Intercontinental Music Lab
http://www.intercontinentalmusiclab.com
Find more Cambridge University research here:
http://www.cam.ac.uk/research
- published: 03 Feb 2012
- views: 1070131
-
-
I can't wait to buy a new cell phone and drop it like this
published: 09 Sep 2016 -
-
-
Sar e Aam crime show ( Don't Give Your Cell No To Beautiful Girls ) – 15th June 2016
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each . The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each . The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
published: 09 Sep 2016 -
Hands on Review T Mobile - 4G LTE Personal cell spot
Boost Connectivity with 4G LTE Cellspsot by TMobile Thumbnail Pic Courtesy - Stock photo from T Mobile website
published: 08 Sep 2016 -
SKYWARS KB DOS INFERNO! FT:T-RedPlayer e CELL X
like para mais skywars! canal do T-redPlayer:https://www.youtube.com/channel/UCqIUvl9mjxD5BbZxHeVUKFQ canal do cell x:https://www.youtube.com/channel/UCYAX8FBLIIFCU7vb0pjBchQ
published: 08 Sep 2016 -
Don't Let your kids play with Old mobile (cell) phones
GSM (and 3G-UTMS) Mobile phones, even without sim cards can call Emergency services (112/911/999/000/111 etc) even when locked - Prank calls to emergency services waste time of the operators and can mean someone who's in need is waiting longer or can't get through - If your phone calls emergency, even by accident - DO NOT HANG UP - Wait until an operator answers, explain the mistake and everyone is happy -
published: 08 Sep 2016 -
Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna
Click here ►► http://amzn.to/1olz1Po Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna Supports voice and 3G data for 3G/4G/LTE mobile phones, including iPhone, Android, Windows Phone, Blackberry, etc. Simple setup process using quick setup guide - Note that you must have an official AT&T account (not a 3rd-party carrier) Status Indicators: Cell Signal, GPS Signal, Internet Connectivity, Power Works at home or the office (broadband internet connection via Ethernet is required) Note that satellite internet connections often have too much delay for this device to work properly High quality design and construction by Cisco Systems, a leader in cellular and network technology B00NZI5QMQ
published: 07 Sep 2016 -
AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Ph...
Click here ►► http://amzn.to/230MvQg AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Phones) Supports voice and 3G data for 3G/4G/LTE mobile phones, including iPhone, Android, Windows Phone, Blackberry, etc. Simple setup process using quick setup guide - Note that you must have an official AT&T account (not a 3rd-party carrier) Status Indicators: Cell Signal, GPS Signal, Internet Connectivity, Power Works at home or the office (broadband internet connection via Ethernet is required) Note that satellite internet connections often have too much delay for this device to work properly High quality design and construction by Cisco Systems, a leader in cellular and network technology B004F1F9P6
published: 06 Sep 2016
Splinter cell:"Road To Blacklist" #3 T'BILISI 2/2
- Order: Reorder
- Duration: 10:06
- Updated: 10 Sep 2016
- views: 5
Ecco il terzo episodio della serie Road To Blacklist in cui completeremo la prima missione a T'bilisi...se il video vi è piaciuto lasciate un like ed iscrivetev...
Ecco il terzo episodio della serie Road To Blacklist in cui completeremo la prima missione a T'bilisi...se il video vi è piaciuto lasciate un like ed iscrivetevi.
wn.com/Splinter Cell Road To Blacklist 3 T'Bilisi 2 2
I can't wait to buy a new cell phone and drop it like this
- Order: Reorder
- Duration: 0:07
- Updated: 09 Sep 2016
- views: 79
- published: 09 Sep 2016
- views: 79
T-Raz ft. Cell "If You Didn't Know (Tha Don) (Prod. T-Raz)
- Order: Reorder
- Duration: 3:36
- Updated: 09 Sep 2016
- views: 37
Torture Cell of N League Politician Discovered Police Can't Arrest Him Coz He is a Politician angry
- Order: Reorder
- Duration: 1:38
- Updated: 09 Sep 2016
- views: 2
Sar e Aam crime show ( Don't Give Your Cell No To Beautiful Girls ) – 15th June 2016
- Order: Reorder
- Duration: 63:53
- Updated: 09 Sep 2016
- views: 0
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of ea...
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
wn.com/Sar E Aam Crime Show ( Don't Give Your Cell No To Beautiful Girls ) – 15Th June 2016
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide. What precisely is a criminal offence is defined by criminal law of each .
- published: 09 Sep 2016
- views: 0
Hands on Review T Mobile - 4G LTE Personal cell spot
- Order: Reorder
- Duration: 3:41
- Updated: 08 Sep 2016
- views: 10
Boost Connectivity with 4G LTE Cellspsot by TMobile
Thumbnail Pic Courtesy - Stock photo from T Mobile website
Boost Connectivity with 4G LTE Cellspsot by TMobile
Thumbnail Pic Courtesy - Stock photo from T Mobile website
wn.com/Hands On Review T Mobile 4G Lte Personal Cell Spot
Boost Connectivity with 4G LTE Cellspsot by TMobile
Thumbnail Pic Courtesy - Stock photo from T Mobile website
- published: 08 Sep 2016
- views: 10
SKYWARS KB DOS INFERNO! FT:T-RedPlayer e CELL X
- Order: Reorder
- Duration: 9:35
- Updated: 08 Sep 2016
- views: 38
like para mais skywars!
canal do T-redPlayer:https://www.youtube.com/channel/UCqIUvl9mjxD5BbZxHeVUKFQ
canal do cell x:https://www.youtube.com/channel/UCYAX8FBL...
like para mais skywars!
canal do T-redPlayer:https://www.youtube.com/channel/UCqIUvl9mjxD5BbZxHeVUKFQ
canal do cell x:https://www.youtube.com/channel/UCYAX8FBLIIFCU7vb0pjBchQ
wn.com/Skywars Kb Dos Inferno Ft T Redplayer E Cell X
like para mais skywars!
canal do T-redPlayer:https://www.youtube.com/channel/UCqIUvl9mjxD5BbZxHeVUKFQ
canal do cell x:https://www.youtube.com/channel/UCYAX8FBLIIFCU7vb0pjBchQ
- published: 08 Sep 2016
- views: 38
Don't Let your kids play with Old mobile (cell) phones
- Order: Reorder
- Duration: 6:25
- Updated: 08 Sep 2016
- views: 13
GSM (and 3G-UTMS) Mobile phones, even without sim cards can call Emergency services (112/911/999/000/111 etc) even when locked - Prank calls to emergency servic...
GSM (and 3G-UTMS) Mobile phones, even without sim cards can call Emergency services (112/911/999/000/111 etc) even when locked - Prank calls to emergency services waste time of the operators and can mean someone who's in need is waiting longer or can't get through -
If your phone calls emergency, even by accident - DO NOT HANG UP - Wait until an operator answers, explain the mistake and everyone is happy -
wn.com/Don't Let Your Kids Play With Old Mobile (Cell) Phones
GSM (and 3G-UTMS) Mobile phones, even without sim cards can call Emergency services (112/911/999/000/111 etc) even when locked - Prank calls to emergency services waste time of the operators and can mean someone who's in need is waiting longer or can't get through -
If your phone calls emergency, even by accident - DO NOT HANG UP - Wait until an operator answers, explain the mistake and everyone is happy -
- published: 08 Sep 2016
- views: 13
Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna
- Order: Reorder
- Duration: 1:51
- Updated: 07 Sep 2016
- views: 130
Click here ►► http://amzn.to/1olz1Po Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna Supports voice and 3G data for 3G/4G/LTE mobile phones,...
Click here ►► http://amzn.to/1olz1Po Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna Supports voice and 3G data for 3G/4G/LTE mobile phones, including iPhone, Android, Windows Phone, Blackberry, etc. Simple setup process using quick setup guide - Note that you must have an official AT&T account (not a 3rd-party carrier) Status Indicators: Cell Signal, GPS Signal, Internet Connectivity, Power Works at home or the office (broadband internet connection via Ethernet is required) Note that satellite internet connections often have too much delay for this device to work properly High quality design and construction by Cisco Systems, a leader in cellular and network technology B00NZI5QMQ
wn.com/Cisco At Amp T Microcell Wireless Cell Signal Booster Tower Antenna
Click here ►► http://amzn.to/1olz1Po Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna Supports voice and 3G data for 3G/4G/LTE mobile phones, including iPhone, Android, Windows Phone, Blackberry, etc. Simple setup process using quick setup guide - Note that you must have an official AT&T account (not a 3rd-party carrier) Status Indicators: Cell Signal, GPS Signal, Internet Connectivity, Power Works at home or the office (broadband internet connection via Ethernet is required) Note that satellite internet connections often have too much delay for this device to work properly High quality design and construction by Cisco Systems, a leader in cellular and network technology B00NZI5QMQ
- published: 07 Sep 2016
- views: 130
AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Ph...
- Order: Reorder
- Duration: 1:46
- Updated: 06 Sep 2016
- views: 138
Click here ►► http://amzn.to/230MvQg AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Phones) Supports voice and 3...
Click here ►► http://amzn.to/230MvQg AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Phones) Supports voice and 3G data for 3G/4G/LTE mobile phones, including iPhone, Android, Windows Phone, Blackberry, etc. Simple setup process using quick setup guide - Note that you must have an official AT&T account (not a 3rd-party carrier) Status Indicators: Cell Signal, GPS Signal, Internet Connectivity, Power Works at home or the office (broadband internet connection via Ethernet is required) Note that satellite internet connections often have too much delay for this device to work properly High quality design and construction by Cisco Systems, a leader in cellular and network technology B004F1F9P6
wn.com/At Amp T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible With 3G, 4G, And Lte Ph...
Click here ►► http://amzn.to/230MvQg AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Phones) Supports voice and 3G data for 3G/4G/LTE mobile phones, including iPhone, Android, Windows Phone, Blackberry, etc. Simple setup process using quick setup guide - Note that you must have an official AT&T account (not a 3rd-party carrier) Status Indicators: Cell Signal, GPS Signal, Internet Connectivity, Power Works at home or the office (broadband internet connection via Ethernet is required) Note that satellite internet connections often have too much delay for this device to work properly High quality design and construction by Cisco Systems, a leader in cellular and network technology B004F1F9P6
- published: 06 Sep 2016
- views: 138
-
T Cell Effector Function: Part 1 -- TH 1 and 2 in Granulomatous Infection, Autoimmunity, and Allergy
Dr. Leonard Calabrese addresses cytokines, biologic roles, and polarization of TH1 and TH2 cell populations. This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology. To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
published: 12 Feb 2013 -
B & T Cell Activation & Development, Cytokines, MHC 1 CD40 TNF B7 IL 2 LTB4 CD4 CD8
http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il-2-ltb4-cd4-cd8/ SKIP AHEAD: 1:04 – Intro to the Adaptive Immune Response & Types of Lymphocytes 3:44 – T & B Cell Function & Activation 7:32 – B & T Cell Development (Hematopoietic Stem Cells, Secondary & Primary Lymphoid Organs) 9:36 – Negative Selection through Central & Peripheral Tolerance 11:18 – Major Histocompatibility Complex (MHC 1 & 2) 13:44 – T Cell Activation: Helper CD4 & Cytotoxic CD8 16:06 – B Cell Activation: T Cell Dependent & Independent 17:54 – Cytokines: Interleukin 1 (IL-1), IL-2, IL-8, Tumor Necrosis Factor (TNF), Interferon There are 2 main types of T-Cell, each of which is part of Cell-Mediated Immunity. CD8 T-cells, named for its CD8 surface marker, are the “Cytotoxic” T...
published: 01 Jan 2015 -
T-Cell Memory and Exhaustion
CEND-20160325-210342_2
published: 26 Apr 2016 -
Immunotherapy: CAR-T Cells - Stephan Grupp, MD, PhD
published: 11 Dec 2014 -
T Cell Effector Function: Part 2 - Th17 and T Regulatory Cells in Health and Disease
Hear Dr. Scott Plevy describe the biologic functions and role of TH17 cells in autoimmune diseases. This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology. To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
published: 12 Feb 2013 -
Nicole Weit - Advanced flow cytometric analysis of human T cell memory subsets
Watch on LabRoots at http://labroots.com/webinar/id/169 T-cells form an integral part of the human immune system by fighting off infection and eliminating transformed cells. Over the last decades numerous T-cells subsets with different functions and abilities have been identified (Farber et al. Nat Rev Immunol 2014). The wide spread use of monoclonal antibodies and multi-color flow cytometry allows for the routine identification of these subsets based on their immune-phenotype (Chattopadhyay et al. Cytometry 2012). However, the increasingly detailed understanding and the dynamic nature of different T-cell subsets also results in a dramatic increase in the complexity of the antibody panels used. Here, we will demonstrate the identification of naïve, memory and effector T cells at various s...
published: 06 Nov 2015 -
T-cell Adoptive Therapy for Melanoma - Melanoma Education Symposium, Patrick Hwu MD
Dr. Patrick Hwu, Deparment Chair of Melanoma Medical Oncology at MD Anderson Cancer Center discusses the future of T-cell adoptive therapy and upcoming clinical trials for metastatic melanoma at the 2013 Melanoma Education Symposium hosted by The Angeles Clinic Foundation and AIM at Melanoma
published: 22 Jul 2013
T Cell Effector Function: Part 1 -- TH 1 and 2 in Granulomatous Infection, Autoimmunity, and Allergy
- Order: Reorder
- Duration: 22:19
- Updated: 12 Feb 2013
- views: 13289
Dr. Leonard Calabrese addresses cytokines, biologic roles, and polarization of TH1 and TH2 cell populations. This webcast is part of an interactive online serie...
Dr. Leonard Calabrese addresses cytokines, biologic roles, and polarization of TH1 and TH2 cell populations. This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
wn.com/T Cell Effector Function Part 1 Th 1 And 2 In Granulomatous Infection, Autoimmunity, And Allergy
Dr. Leonard Calabrese addresses cytokines, biologic roles, and polarization of TH1 and TH2 cell populations. This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
- published: 12 Feb 2013
- views: 13289
B & T Cell Activation & Development, Cytokines, MHC 1 CD40 TNF B7 IL 2 LTB4 CD4 CD8
- Order: Reorder
- Duration: 20:59
- Updated: 01 Jan 2015
- views: 14043
http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il-2-ltb4-cd4-cd8/
SKIP AHEAD:
1:04 – Intro to the Adaptive Immune Respo...
http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il-2-ltb4-cd4-cd8/
SKIP AHEAD:
1:04 – Intro to the Adaptive Immune Response & Types of Lymphocytes
3:44 – T & B Cell Function & Activation
7:32 – B & T Cell Development (Hematopoietic Stem Cells, Secondary & Primary Lymphoid Organs)
9:36 – Negative Selection through Central & Peripheral Tolerance
11:18 – Major Histocompatibility Complex (MHC 1 & 2)
13:44 – T Cell Activation: Helper CD4 & Cytotoxic CD8
16:06 – B Cell Activation: T Cell Dependent & Independent
17:54 – Cytokines: Interleukin 1 (IL-1), IL-2, IL-8, Tumor Necrosis Factor (TNF), Interferon
There are 2 main types of T-Cell, each of which is part of Cell-Mediated Immunity. CD8 T-cells, named for its CD8 surface marker, are the “Cytotoxic” T-Cell. These lymphocytes release perforin and granzyme to cause lysis of infected cells, similar to how NK cells function. These CD8 cells cause apoptosis of cells that are infected by intracellular pathogens (primarily viruses and intracellular bacteria like chlamydia). Cytotoxic T-Cells also play a role in triggering apoptosis of cancerous cells. CD4 T-Cells, named for their CD4 surface marker, are referred to as the “Helper” T-cells. They do not fight pathogens directly, but help various other cells to do so by releasing cytokines signals. There are 2 subtypes of CD4 Helper T-Cells, Th1 and Th2. Th1 Helper T-Cells primarily activate cytotoxic CD8 T-cells and Macrophages. Th2 helper T-cells primarily activate B-Cells.
Both T-Cells & B-Cells begin life in the bone marrow and arise from multipotent hematopoietic stem cells. Immature B-Cells remain in the bone marrow to complete maturation (Think B for Bone Marrow), while the immature T-Cells leave the bone marrow and travel to the thymus to complete maturation (Think T for Thymus). The bone marrow and thymus are referred to as Primary Lymphoid Organs. These Primary Lymphoid Organs are where B-Cells and T-Cells differentiate and mature. Absence of a primary lymphoid organ, such as the absence of the thymus in DiGeorge Syndrome, prevents the normal development of white blood cells and can lead to immunodeficiency.
Once mature, B-Cells and T-Cells move to Secondary Lymphoid Organs such as the lymph node and spleen. This is where these cells come into contact with foreign pathogens. If the pathogen the cell can interact with is present the cell will be activated. After activation the cells proliferate making clones of themselves that are all capable of recognizing and fighting against the same antigen. However, not all T & B Cells will be activated. A large majority of these cells will not encounter the type of foreign material they recognize. If the foreign material the B or T Cell can fight against isn’t present in the body there is no need to be activated.
The foreign material or pathogen that the T & B Cells recognize is determined by their unique surface receptors. An Antigen is the specific structural sequence the receptor can bind to. For example, a protein fragment of a pathogen you want to mount an immune response against. All of the receptors on a given T or B Cell are the same and recognize the same antigen. When the receptor binds to the appropriate antigen it signals the cell to become activated and proliferate. You need a nearly infinite variability in these receptors so that you can fight almost any pathogen encountered. Therefore, while the leukocytes are in the primary lymphoid organs a wide variety of receptor variability is randomly generated through VDJ Recombination. This change in the portion of the genome that encodes for the cell’s receptors allows the different leukocytes to interact with a huge variety of antigens.
The problem with randomly generating surface receptors is that some of these leukocytes will now be able to bind the body’s own cells. If these self-reactive lymphocytes where activated they would cause autoimmune damage where the immune system targets the body’s tissue instead of foreign material. The body has a 2 step process for preventing this called Negative Selection. In the primary lymphoid organs self-reactive leukocytes are removed by Central Tolerance (AKA Clonal Deletion). Developing T & B lymphocytes that interact too strongly with self-antigens undergo apoptosis or programmed cell death. In the secondary lymphoid organs there is a similar process called Peripheral Tolerance or Clonal Anergy. Here self-reactive T or B Cells that bind to soluble self-antigens undergo anergy. Anergy is when a cell is prevented from becoming active. These anergic cells are not killed, but they are prevented from proliferating.
The text for this video is too long and exceeds the maximum allowed length by youtube. To see the full text please go here http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il-2-ltb4-cd4-cd8/
wn.com/B T Cell Activation Development, Cytokines, Mhc 1 Cd40 Tnf B7 Il 2 Ltb4 Cd4 Cd8
http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il-2-ltb4-cd4-cd8/
SKIP AHEAD:
1:04 – Intro to the Adaptive Immune Response & Types of Lymphocytes
3:44 – T & B Cell Function & Activation
7:32 – B & T Cell Development (Hematopoietic Stem Cells, Secondary & Primary Lymphoid Organs)
9:36 – Negative Selection through Central & Peripheral Tolerance
11:18 – Major Histocompatibility Complex (MHC 1 & 2)
13:44 – T Cell Activation: Helper CD4 & Cytotoxic CD8
16:06 – B Cell Activation: T Cell Dependent & Independent
17:54 – Cytokines: Interleukin 1 (IL-1), IL-2, IL-8, Tumor Necrosis Factor (TNF), Interferon
There are 2 main types of T-Cell, each of which is part of Cell-Mediated Immunity. CD8 T-cells, named for its CD8 surface marker, are the “Cytotoxic” T-Cell. These lymphocytes release perforin and granzyme to cause lysis of infected cells, similar to how NK cells function. These CD8 cells cause apoptosis of cells that are infected by intracellular pathogens (primarily viruses and intracellular bacteria like chlamydia). Cytotoxic T-Cells also play a role in triggering apoptosis of cancerous cells. CD4 T-Cells, named for their CD4 surface marker, are referred to as the “Helper” T-cells. They do not fight pathogens directly, but help various other cells to do so by releasing cytokines signals. There are 2 subtypes of CD4 Helper T-Cells, Th1 and Th2. Th1 Helper T-Cells primarily activate cytotoxic CD8 T-cells and Macrophages. Th2 helper T-cells primarily activate B-Cells.
Both T-Cells & B-Cells begin life in the bone marrow and arise from multipotent hematopoietic stem cells. Immature B-Cells remain in the bone marrow to complete maturation (Think B for Bone Marrow), while the immature T-Cells leave the bone marrow and travel to the thymus to complete maturation (Think T for Thymus). The bone marrow and thymus are referred to as Primary Lymphoid Organs. These Primary Lymphoid Organs are where B-Cells and T-Cells differentiate and mature. Absence of a primary lymphoid organ, such as the absence of the thymus in DiGeorge Syndrome, prevents the normal development of white blood cells and can lead to immunodeficiency.
Once mature, B-Cells and T-Cells move to Secondary Lymphoid Organs such as the lymph node and spleen. This is where these cells come into contact with foreign pathogens. If the pathogen the cell can interact with is present the cell will be activated. After activation the cells proliferate making clones of themselves that are all capable of recognizing and fighting against the same antigen. However, not all T & B Cells will be activated. A large majority of these cells will not encounter the type of foreign material they recognize. If the foreign material the B or T Cell can fight against isn’t present in the body there is no need to be activated.
The foreign material or pathogen that the T & B Cells recognize is determined by their unique surface receptors. An Antigen is the specific structural sequence the receptor can bind to. For example, a protein fragment of a pathogen you want to mount an immune response against. All of the receptors on a given T or B Cell are the same and recognize the same antigen. When the receptor binds to the appropriate antigen it signals the cell to become activated and proliferate. You need a nearly infinite variability in these receptors so that you can fight almost any pathogen encountered. Therefore, while the leukocytes are in the primary lymphoid organs a wide variety of receptor variability is randomly generated through VDJ Recombination. This change in the portion of the genome that encodes for the cell’s receptors allows the different leukocytes to interact with a huge variety of antigens.
The problem with randomly generating surface receptors is that some of these leukocytes will now be able to bind the body’s own cells. If these self-reactive lymphocytes where activated they would cause autoimmune damage where the immune system targets the body’s tissue instead of foreign material. The body has a 2 step process for preventing this called Negative Selection. In the primary lymphoid organs self-reactive leukocytes are removed by Central Tolerance (AKA Clonal Deletion). Developing T & B lymphocytes that interact too strongly with self-antigens undergo apoptosis or programmed cell death. In the secondary lymphoid organs there is a similar process called Peripheral Tolerance or Clonal Anergy. Here self-reactive T or B Cells that bind to soluble self-antigens undergo anergy. Anergy is when a cell is prevented from becoming active. These anergic cells are not killed, but they are prevented from proliferating.
The text for this video is too long and exceeds the maximum allowed length by youtube. To see the full text please go here http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il-2-ltb4-cd4-cd8/
- published: 01 Jan 2015
- views: 14043
T-Cell Memory and Exhaustion
- Order: Reorder
- Duration: 35:50
- Updated: 26 Apr 2016
- views: 92
CEND-20160325-210342_2
CEND-20160325-210342_2
wn.com/T Cell Memory And Exhaustion
CEND-20160325-210342_2
- published: 26 Apr 2016
- views: 92
Immunotherapy: CAR-T Cells - Stephan Grupp, MD, PhD
- Order: Reorder
- Duration: 52:23
- Updated: 11 Dec 2014
- views: 9698
- published: 11 Dec 2014
- views: 9698
T Cell Effector Function: Part 2 - Th17 and T Regulatory Cells in Health and Disease
- Order: Reorder
- Duration: 45:59
- Updated: 12 Feb 2013
- views: 10577
Hear Dr. Scott Plevy describe the biologic functions and role of TH17 cells in autoimmune diseases. This webcast is part of an interactive online series designe...
Hear Dr. Scott Plevy describe the biologic functions and role of TH17 cells in autoimmune diseases. This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
wn.com/T Cell Effector Function Part 2 Th17 And T Regulatory Cells In Health And Disease
Hear Dr. Scott Plevy describe the biologic functions and role of TH17 cells in autoimmune diseases. This webcast is part of an interactive online series designed to bring you, the busy clinician, up to speed with the remarkable advances occurring every day in the field of basic and clinical immunology.
To learn more or to claim CME credit, visit http://www.ccfcme.org/TCell
This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology.
- published: 12 Feb 2013
- views: 10577
Nicole Weit - Advanced flow cytometric analysis of human T cell memory subsets
- Order: Reorder
- Duration: 58:25
- Updated: 06 Nov 2015
- views: 683
Watch on LabRoots at http://labroots.com/webinar/id/169
T-cells form an integral part of the human immune system by fighting off infection and eliminating trans...
Watch on LabRoots at http://labroots.com/webinar/id/169
T-cells form an integral part of the human immune system by fighting off infection and eliminating transformed cells. Over the last decades numerous T-cells subsets with different functions and abilities have been identified (Farber et al. Nat Rev Immunol 2014). The wide spread use of monoclonal antibodies and multi-color flow cytometry allows for the routine identification of these subsets based on their immune-phenotype (Chattopadhyay et al. Cytometry 2012). However, the increasingly detailed understanding and the dynamic nature of different T-cell subsets also results in a dramatic increase in the complexity of the antibody panels used.
Here, we will demonstrate the identification of naïve, memory and effector T cells at various stages of differentiation, but also the detection of rare populations such as stem cell like memory T cells and different Treg subpopulations using a 13-color marker combination that allows for the identification of T cell subtypes according to classical and more recent characterization criteria. We will outline the panel design rational taking into account expression patterns as well as fluorochrome characteristics. The applied gating strategies will be discussed.
wn.com/Nicole Weit Advanced Flow Cytometric Analysis Of Human T Cell Memory Subsets
Watch on LabRoots at http://labroots.com/webinar/id/169
T-cells form an integral part of the human immune system by fighting off infection and eliminating transformed cells. Over the last decades numerous T-cells subsets with different functions and abilities have been identified (Farber et al. Nat Rev Immunol 2014). The wide spread use of monoclonal antibodies and multi-color flow cytometry allows for the routine identification of these subsets based on their immune-phenotype (Chattopadhyay et al. Cytometry 2012). However, the increasingly detailed understanding and the dynamic nature of different T-cell subsets also results in a dramatic increase in the complexity of the antibody panels used.
Here, we will demonstrate the identification of naïve, memory and effector T cells at various stages of differentiation, but also the detection of rare populations such as stem cell like memory T cells and different Treg subpopulations using a 13-color marker combination that allows for the identification of T cell subtypes according to classical and more recent characterization criteria. We will outline the panel design rational taking into account expression patterns as well as fluorochrome characteristics. The applied gating strategies will be discussed.
- published: 06 Nov 2015
- views: 683
T-cell Adoptive Therapy for Melanoma - Melanoma Education Symposium, Patrick Hwu MD
- Order: Reorder
- Duration: 23:09
- Updated: 22 Jul 2013
- views: 3373
Dr. Patrick Hwu, Deparment Chair of Melanoma Medical Oncology at MD Anderson Cancer Center discusses the future of T-cell adoptive therapy and upcoming clinical...
Dr. Patrick Hwu, Deparment Chair of Melanoma Medical Oncology at MD Anderson Cancer Center discusses the future of T-cell adoptive therapy and upcoming clinical trials for metastatic melanoma at the 2013 Melanoma Education Symposium hosted by The Angeles Clinic Foundation and AIM at Melanoma
wn.com/T Cell Adoptive Therapy For Melanoma Melanoma Education Symposium, Patrick Hwu Md
Dr. Patrick Hwu, Deparment Chair of Melanoma Medical Oncology at MD Anderson Cancer Center discusses the future of T-cell adoptive therapy and upcoming clinical trials for metastatic melanoma at the 2013 Melanoma Education Symposium hosted by The Angeles Clinic Foundation and AIM at Melanoma
- published: 22 Jul 2013
- views: 3373
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11:07
Review of B cells, CD4+ T cells and CD8+ T cells
Review of B cells, CD4+ T cells and CD8+ T cells
More free lessons at: http://www.khanaca...
published: 19 Feb 2010
Review of B cells, CD4+ T cells and CD8+ T cells
Review of B cells, CD4+ T cells and CD8+ T cells
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- published: 19 Feb 2010
- views: 573738
20:34
Helper T Cells
Introduction to helper T cells and their role in activating B cells
More free lessons at: ...
published: 19 Feb 2010
Helper T Cells
Helper T Cells
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- published: 19 Feb 2010
- views: 669786
3:38
T-Cell Activation
published: 02 Jan 2014
T-Cell Activation
T-Cell Activation
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- published: 02 Jan 2014
- views: 40053
6:56
Immunology Map III - T cell development I
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published: 20 Jan 2013
Immunology Map III - T cell development I
Immunology Map III - T cell development I
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- published: 20 Jan 2013
- views: 106614
1:55
Killer T Cell: The Cancer Assassin
How does a Killer T Cell Kill its target?
Our new film captures the behaviour of cytotoxi...
published: 19 May 2015
Killer T Cell: The Cancer Assassin
Killer T Cell: The Cancer Assassin
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- published: 19 May 2015
- views: 567740
32:37
T cell development
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study mater...
published: 20 Nov 2013
T cell development
T cell development
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- published: 20 Nov 2013
- views: 12139
10:00
T Cell Development
http://www.handwrittentutorials.com - This tutorial explores the development of T Cells, f...
published: 21 Aug 2012
T Cell Development
T Cell Development
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- published: 21 Aug 2012
- views: 80104
26:36
T Cell Activation and Control
Dr. John Looney reviews T cell activation contributors, T cell antigen recognition, and T ...
published: 12 Feb 2013
T Cell Activation and Control
T Cell Activation and Control
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- published: 12 Feb 2013
- views: 103121
10:07
Cytotoxic T Cells
How cytotoxic T cells get activated by MHC-I/antigen complexes and then proceed to kill in...
published: 19 Feb 2010
Cytotoxic T Cells
Cytotoxic T Cells
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- published: 19 Feb 2010
- views: 346674
1:02
Killer T cell attacking cancer
Cambridge University's Under the Microscope is a collection of videos that show glimpses o...
published: 03 Feb 2012
Killer T cell attacking cancer
Killer T cell attacking cancer
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- published: 03 Feb 2012
- views: 1070131
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10:06
Splinter cell:"Road To Blacklist" #3 T'BILISI 2/2
Ecco il terzo episodio della serie Road To Blacklist in cui completeremo la prima missione...
published: 10 Sep 2016
Splinter cell:"Road To Blacklist" #3 T'BILISI 2/2
Splinter cell:"Road To Blacklist" #3 T'BILISI 2/2
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- published: 10 Sep 2016
- views: 5
0:07
I can't wait to buy a new cell phone and drop it like this
published: 09 Sep 2016
I can't wait to buy a new cell phone and drop it like this
I can't wait to buy a new cell phone and drop it like this
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- published: 09 Sep 2016
- views: 79
3:36
T-Raz ft. Cell "If You Didn't Know (Tha Don) (Prod. T-Raz)
First song off of T-Raz new tape "All On Me" Releasing early 2017 Turn Up!!!!
published: 09 Sep 2016
T-Raz ft. Cell "If You Didn't Know (Tha Don) (Prod. T-Raz)
T-Raz ft. Cell "If You Didn't Know (Tha Don) (Prod. T-Raz)
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- published: 09 Sep 2016
- views: 37
1:38
Torture Cell of N League Politician Discovered Police Can't Arrest Him Coz He is a Politician angry
Torture Cell of N League Politician Discovered Police Can't Arrest Him Coz He is a Politic...
published: 09 Sep 2016
Torture Cell of N League Politician Discovered Police Can't Arrest Him Coz He is a Politician angry
Torture Cell of N League Politician Discovered Police Can't Arrest Him Coz He is a Politician angry
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- published: 09 Sep 2016
- views: 2
63:53
Sar e Aam crime show ( Don't Give Your Cell No To Beautiful Girls ) – 15th June 2016
The notion that acts such as murder, rape and theft are to be prohibited exists worldwide....
published: 09 Sep 2016
Sar e Aam crime show ( Don't Give Your Cell No To Beautiful Girls ) – 15th June 2016
Sar e Aam crime show ( Don't Give Your Cell No To Beautiful Girls ) – 15th June 2016
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- published: 09 Sep 2016
- views: 0
3:41
Hands on Review T Mobile - 4G LTE Personal cell spot
Boost Connectivity with 4G LTE Cellspsot by TMobile
Thumbnail Pic Courtesy - Stock photo ...
published: 08 Sep 2016
Hands on Review T Mobile - 4G LTE Personal cell spot
Hands on Review T Mobile - 4G LTE Personal cell spot
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- published: 08 Sep 2016
- views: 10
9:35
SKYWARS KB DOS INFERNO! FT:T-RedPlayer e CELL X
like para mais skywars!
canal do T-redPlayer:https://www.youtube.com/channel/UCqIUvl9mjxD...
published: 08 Sep 2016
SKYWARS KB DOS INFERNO! FT:T-RedPlayer e CELL X
SKYWARS KB DOS INFERNO! FT:T-RedPlayer e CELL X
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- published: 08 Sep 2016
- views: 38
6:25
Don't Let your kids play with Old mobile (cell) phones
GSM (and 3G-UTMS) Mobile phones, even without sim cards can call Emergency services (112/9...
published: 08 Sep 2016
Don't Let your kids play with Old mobile (cell) phones
Don't Let your kids play with Old mobile (cell) phones
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- published: 08 Sep 2016
- views: 13
1:51
Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna
Click here ►► http://amzn.to/1olz1Po Cisco AT&T Microcell Wireless Cell Signal Booster...
published: 07 Sep 2016
Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna
Cisco AT&T Microcell Wireless Cell Signal Booster Tower Antenna
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- published: 07 Sep 2016
- views: 130
1:46
AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Ph...
Click here ►► http://amzn.to/230MvQg AT&T Microcell Wireless Cell Signal Booster Tower...
published: 06 Sep 2016
AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Ph...
AT&T Microcell Wireless Cell Signal Booster Tower Antenna (Compatible with 3G, 4G, and LTE Ph...
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- published: 06 Sep 2016
- views: 138
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22:19
T Cell Effector Function: Part 1 -- TH 1 and 2 in Granulomatous Infection, Autoimmunity, and Allergy
Dr. Leonard Calabrese addresses cytokines, biologic roles, and polarization of TH1 and TH2...
published: 12 Feb 2013
T Cell Effector Function: Part 1 -- TH 1 and 2 in Granulomatous Infection, Autoimmunity, and Allergy
T Cell Effector Function: Part 1 -- TH 1 and 2 in Granulomatous Infection, Autoimmunity, and Allergy
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- published: 12 Feb 2013
- views: 13289
20:59
B & T Cell Activation & Development, Cytokines, MHC 1 CD40 TNF B7 IL 2 LTB4 CD4 CD8
http://www.stomponstep1.com/b-t-cell-activation-development-cytokines-mhc-1-cd40-tnf-b7-il...
published: 01 Jan 2015
B & T Cell Activation & Development, Cytokines, MHC 1 CD40 TNF B7 IL 2 LTB4 CD4 CD8
B & T Cell Activation & Development, Cytokines, MHC 1 CD40 TNF B7 IL 2 LTB4 CD4 CD8
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- published: 01 Jan 2015
- views: 14043
35:50
T-Cell Memory and Exhaustion
CEND-20160325-210342_2
published: 26 Apr 2016
T-Cell Memory and Exhaustion
T-Cell Memory and Exhaustion
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- published: 26 Apr 2016
- views: 92
52:23
Immunotherapy: CAR-T Cells - Stephan Grupp, MD, PhD
published: 11 Dec 2014
Immunotherapy: CAR-T Cells - Stephan Grupp, MD, PhD
Immunotherapy: CAR-T Cells - Stephan Grupp, MD, PhD
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- published: 11 Dec 2014
- views: 9698
45:59
T Cell Effector Function: Part 2 - Th17 and T Regulatory Cells in Health and Disease
Hear Dr. Scott Plevy describe the biologic functions and role of TH17 cells in autoimmune ...
published: 12 Feb 2013
T Cell Effector Function: Part 2 - Th17 and T Regulatory Cells in Health and Disease
T Cell Effector Function: Part 2 - Th17 and T Regulatory Cells in Health and Disease
- Report rights infringement
- published: 12 Feb 2013
- views: 10577
58:25
Nicole Weit - Advanced flow cytometric analysis of human T cell memory subsets
Watch on LabRoots at http://labroots.com/webinar/id/169
T-cells form an integral part of t...
published: 06 Nov 2015
Nicole Weit - Advanced flow cytometric analysis of human T cell memory subsets
Nicole Weit - Advanced flow cytometric analysis of human T cell memory subsets
- Report rights infringement
- published: 06 Nov 2015
- views: 683
23:09
T-cell Adoptive Therapy for Melanoma - Melanoma Education Symposium, Patrick Hwu MD
Dr. Patrick Hwu, Deparment Chair of Melanoma Medical Oncology at MD Anderson Cancer Center...
published: 22 Jul 2013
T-cell Adoptive Therapy for Melanoma - Melanoma Education Symposium, Patrick Hwu MD
T-cell Adoptive Therapy for Melanoma - Melanoma Education Symposium, Patrick Hwu MD
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- published: 22 Jul 2013
- views: 3373
T Cell Effector Function: Part 1 -- TH 1 and 2 in ...
B & T Cell Activation & Development, Cytokines, MH...
T-Cell Memory and Exhaustion...
Immunotherapy: CAR-T Cells - Stephan Grupp, MD, Ph...
T Cell Effector Function: Part 2 - Th17 and T Regu...
Nicole Weit - Advanced flow cytometric analysis of...
T-cell Adoptive Therapy for Melanoma - Melanoma Ed...
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Lyrics list:lyrics
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The Day I Die
-
Echoes
-
Pushed Into Ruin
-
These Stings
-
Forget Everything
-
Unspoken
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Viper
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Forever The Enemy
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Cross The Great Divide
The Day I Die
Among the edge of life I turn myself
The mirror shows past days times of light
More times of darkness unsettled I stand
Towards the gods of hate
The ones to whom I prayed
Transcience of life now a manifest
Fragmentary tales of yesterday - I back myself
Some things pretended more things I regret
Here I stand between the gods of emptiness
The ones that determined my life
Transcience of life now a manifest
Am I going to rest?
Not today, not tonight, not tomorrow
Not today - the day I die
Mirror falls to pieces - the day I die
Am I going to rest?
photo: NASA / JPL-Caltech/MSSS
UFO Enthusiast Claims Discovery Of Ancient Alien Writing On ‘Abandoned Spacecraft’ On Mars
Edit Inquisitr 17 Sep 2016
A UFO enthusiast has claimed to have discovered what appears to be an “abandoned spaceship” on Mars. And that’s not all. The supposed craft, captured in a NASA Mars photo, has strange markings in the manner of hieroglyphs on its surface that the enthusiast believes could very well be a form of alien writing ... UFOmania described the object ... Scott C ... One commenter insisted all that was discovered was a rock....
photo: GFDL / Whit Welles
[VIDEO] Humpback Whales Interrupt Man Doing Pushups On His Kayak
Edit WorldNews.com 16 Sep 2016
The challenge asks participants to complete 22 pushups for 22 days.Pelayo was switching it up a little bit by performing his pushups on a kayak in the middle of the ocean off Grover Beach near San Luis Obispo, California....
photo: AP / Manuel Balce Ceneta
[UPDATE]: Trump Admits Obama Born In US, Blames Clinton For Birther Issue
Edit WorldNews.com 16 Sep 2016
In the blink of an eye, Republican presidential candidate Donald Trump admitted what has taken him 5+ years to admit Friday. U.S. President Barack Obama “was born in the United States. Period,” Variety reported ... As he weighed whether to run for president in 2012, Trump capitalized on media publicity as he pushed the birther theory ... “Trump’s actions today were disgraceful....
photo: UN / Kim Haughton
U.N. chief: Israeli's comment on ethnic cleansing 'outrageous'
Edit Arkansas Online 17 Sep 2016
UNITED NATIONS -- Secretary-General Ban Ki-moon on Thursday called Israeli Prime Minister Benjamin Netanyahu's insistence that Palestinians want the "ethnic cleansing" of Jews in the West Bank "unacceptable and outrageous.". Ban told the U.N. Security Council that he wanted to be absolutely clear. "Settlements are illegal under international law." ... U.S ... Israel's U.N ... Power said the U.S ... A Section on 09/17/2016 ....
photo: Creative Commons / Gage Skidmore
Third-Party Candidates Excluded From First U.S. Presidential Debate
Edit WorldNews.com 16 Sep 2016
The commission that oversees U.S. presidential debates has invited only Hillary Clinton and Donald Trump to the first presidential debate, The Associated Press reports ... 26 event. The commission since 2000 has invited only candidates polling at 15 percent or above in an average of five polls....
« back to news headlines
BrainStorm CEO to Present at Two Investor Conferences in September (Brainstorm Cell Therapeutics Inc)
Edit Public Technologies 17 Sep 2016
Brainstorm Cell Therapeutics Inc) ... 6, 2016 /PRNewswire/ -- BrainStorm Cell Therapeutics Inc ... BCLI), a leading developer of adult stem cell technologies for neurodegenerative diseases, announced today that Chaim Lebovits, Chief Executive Officer, will provide a corporate overview at two upcoming investor conferences ... About BrainStorm Cell Therapeutics Inc. BrainStorm Cell Therapeutics Inc ... Brainstorm Cell Therapeutics Inc....
Govindachamy may be shifted to regular cell
Edit The Times of India 17 Sep 2016
As Govindachamy is no longer a death row prisoner, he will be assigned works normally given to life-term prisoners and will be accommodated in regular cell blocks, along with other prisoners ... If needed, we will shift him to another cell but no decision has been taken yet," said the superintendent in charge Ashokan Arippa ... Hence, a section of the prison officials do not see any major problem in shifting him to another cell....
Dissident who had list of police and judges in his cell is jailed for a further 12 months
Edit Belfast Telegraph 17 Sep 2016Mast Therapeutics Joins New Sickle Cell Disease Coalition, Supports Campaign To Improve Treatment And Care (Mast Therapeutics Inc)
Edit Public Technologies 17 Sep 2016
MSTX), a biopharmaceutical company developing novel, clinical-stage therapies for sickle cell disease and heart failure, today announced that it is joining other industry leaders, patient advocacy groups, researchers, clinicians, policymakers, and foundations in a collective effort to improve sickle cell disease (SCD) care, early diagnosis, treatment, and research both in the United States and globally....
Tip sheet: Combustible cell phone batteries should concern all smartphone makers (George Mason University)
Edit Public Technologies 17 Sep 2016
(Source. George Mason University) ... 'Today's cell phone companies are mainly relying on lithium ion batteries to power up their phones,' said Houman Homayoun, assistant professor in the Electrical and Computer Engineering Department in George Mason's Volgenau School of Engineering. 'However, lithium, which is a silver white metal material, can catch fire easily, especially when it is exposed to oxygen.' ... About George Mason ... (noodl....
CytRx Announces the Completion of Enrollment in Its Global Phase 2b Clinical Trial of Aldoxorubicin in Patients with Second-Line Small Cell Lung Cancer (CytRx Corporation)
Edit Public Technologies 17 Sep 2016
CYTR), a biopharmaceutical research and development company specializing in oncology, today announced that it has reached its enrollment target of 132 patients for the company's global Phase 2b clinical trial of aldoxorubicin in patients with previously treated small cell lung cancer (SCLC) ... About Small Cell Lung Cancer....
FDA Approves BLINCYTO® (blinatumomab) For Use In Pediatric Patients With Philadelphia Chromosome-Negative Relapsed Or Refractory B-cell Precursor Acute Lymphoblastic Leukemia (Amgen Inc)
Edit Public Technologies 17 Sep 2016
Food and Drug Administration (FDA) has approved the supplemental Biologics License Application (sBLA) for BLINCYTO(blinatumomab) to include new data supporting the treatment of pediatric patients with Philadelphia chromosome-negative (Ph-) relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) ... for the treatment of Ph- relapsed or refractory B-cell precursor ALL....
Ministry of Labor starts secret cell phone shop inspections
Edit Arabnews 17 Sep 2016
Author. . ARAB NEWS. Sat, 2016-09-17. ID. . 1474062284576268700. RIYADH. The Ministry of Labor and Social Development confirmed it has directed secret inspections on mobile phone sale and maintenance facilities to monitor violations, and to impose punishments on violators. Main category. . Saudi Arabia ... ....
Amgen Obtains Global Development And Commercial Rights From Boehringer Ingelheim For Investigational BiTE® Immuno-Oncology Drug For Multiple Myeloma (Amgen Inc)
Edit Public Technologies 17 Sep 2016
Immuno-oncology and T cell engagers remain a key area of focus for Boehringer Ingelheim as well as providing innovative treatments for lung and blood cancers.' ... on multiple myeloma cells ... This includes non-small cell lung cancer, squamous cell carcinoma of the lung, acute myeloid leukemia, chronic lymphocytic leukemia and myelodysplastic syndromes....
Dissidents granted leave to challenge lock-up order
Edit Belfast Telegraph 17 Sep 2016
Two dissident republican prisoners confined to cells for refusing jailhouse orders have won High Court permission to challenge the adjudication process. Londonderry men Seamus McLaughlin (39) and Nathan Hastings (23) were granted leave to seek a judicial review of decisions to find them guilty of refusing orders to lock up their cells....
Varsity develops gadget to spot cancer in 30 minutes
Edit The Times of India 17 Sep 2016
The signals that came from the material, based on principles of Raman spectroscopy, showed distinct patterns, and Nair thought why not bounce laser off human tissue to detect abnormal cells like cancer ... The technology uses a laser with a nano substrate to detect pre-cancerous and cancerous cells. Use of laser to read the nature of cells is not new, but the signals that have been found to be weak and difficult to analyze....
Yingli to Launch New UL-Certified PV Module Series in the U.S. (Yingli Green Energy Holding Company Limited)
Edit Public Technologies 17 Sep 2016
Besides, Yingli's TwinMAX 60 Cell is a frameless module comprised of two layers of 2.5 mm thick semi-tempered glass, which replaced the conventional back sheet and glass structure ... YLM Series are available in both 60-cell and 72-cell series which enhances its versatility for a wide range of applications going from residential and commercial projects to large-scale power plants....
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