Cetyl myristoleate

Cetyl myristoleate is a chemical compound which is a type of fatty acid ester or, more specifically, a cetylated fatty acid (CFA). It is the cetyl ester of myristoleic acid. Although it is used as a dietary supplement, there is little clinical evidence to support a benefit for any medical condition.

Synthesis

Cetyl myristoleate has been prepared by an esterification reaction between myristoleic acid and cetyl alcohol, catalyzed by p-toluenesulfonic acid monohydrate.

Animal pharmacology

In animal studies, cetyl myristoleate was first reported to block inflammation and prevent adjuvant-induced arthritis at very high doses in rats. Other studies using identical and similar methods have failed to replicate this effect. In follow-up studies in mice, a modest anti-inflammatory effect was observed.

Study in humans

Although cetyl myristoleate is sold as a dietary supplement, its possible benefits in the treatment of any medical condition are largely unknown and the Federal Trade Commission has taken legal action against supplement manufacturers for exaggerated claims.