DNA

Deoxyribonucleic acid (ⁱ/diˈɒksiˌraɪboʊnjʊˌkliːɪk, -ˌkleɪɪk/;DNA) is a molecule that carries most of the genetic instructions used in the development, functioning and reproduction of all known living organisms and many viruses. DNA is a nucleic acid; alongside proteins and carbohydrates, nucleic acids compose the three major macromolecules essential for all known forms of life. Most DNA molecules consist of two biopolymer strands coiled around each other to form a double helix. The two DNA strands are known as polynucleotides since they are composed of simpler units called nucleotides. Each nucleotide is composed of a nitrogen-containing nucleobase—either cytosine (C), guanine (G), adenine (A), or thymine (T)—as well as a monosaccharide sugar called deoxyribose and a phosphate group. The nucleotides are joined to one another in a chain by covalent bonds between the sugar of one nucleotide and the phosphate of the next, resulting in an alternating sugar-phosphate backbone. According to base pairing rules (A with T, and C with G), hydrogen bonds bind the nitrogenous bases of the two separate polynucleotide strands to make double-stranded DNA. The total amount of related DNA base pairs on Earth is estimated at 5.0 x 10³⁷, and weighs 50 billion tonnes. In comparison, the total mass of the biosphere has been estimated to be as much as 4 TtC (trillion tons of carbon).

Girlfriend

A girlfriend is a female friend or acquaintance, often specifying a regular female companion with whom one is platonic, romantically and/or sexually involved. This could be a long-term committed relationship. This is normally a short-term committed relationship, where other titles (e.g. wife, partner) are more commonly used for long-term committed relationships. A girlfriend can also be called an admirer, beau, suitor and sweetheart.

Scope

Partners in committed relationships are also sometimes described as a "significant other" or simply "partner", especially if the individuals are cohabiting.

"Girlfriend" and "partner" mean different things to different people; the distinctions between the terms are subjective. How the term is used will ultimately be determined by personal preference.

In 2005, a study was conducted of 115 people ages 21 to 35 who were either living with or had lived with a romantic partner. It notes that the lack of proper terms often leads to awkward situations, such as someone becoming upset over not being introduced in social situations to avoid the question.

A-DNA

A-DNA is one of the possible double helical structures which DNA can adopt. A-DNA is thought to be one of three biologically active double helical structures along with B-DNA and Z-DNA. It is a right-handed double helix fairly similar to the more common B-DNA form, but with a shorter, more compact helical structure whose base pairs are not perpendicular to the helix-axis as in B-DNA. It was discovered by Rosalind Franklin, who also named the A and B forms. She showed that DNA is driven into the A form when under dehydrating conditions. Such conditions are commonly used in to form crystals, and many DNA crystal structures are in the A form. The same helical conformation occurs in double-stranded RNAs, and in DNA-RNA hybrid double helices.

Structure

A-DNA is fairly similar to B-DNA given that it is a right-handed double helix with major and minor grooves. However, as shown in the comparison table below, there is a slight increase in the number of base pairs (bp) per turn (resulting in a smaller twist angle), and smaller rise per per base pair (making A-DNA 20-25% shorter than B-DNA). The major groove of A-DNA is deep and narrow, while the minor groove is wide and shallow.

Jeremy Kyle

Jeremy Nicholas Kyle (born 7 July 1965) is an English radio and television presenter, best known for hosting the controversial tabloid talk show The Jeremy Kyle Show on ITV since 2005. In 2011, Kyle began hosting a U.S. version of his eponymous show; the U.S. version ran for two seasons.

Early life

Kyle was born in Reading, Berkshire. His father was an accountant and personal secretary to the Queen Mother. He attended the Reading Blue Coat School, an all-boys independent school in Sonning, Berkshire. He studied History and Sociology at the University of Surrey in Guildford.

Radio career

From 1986 to 1995, Kyle worked as a life insurance salesman, recruitment consultant, and radio advertising salesman. He then became a radio presenter and after a brief stint at Orchard FM in Taunton, Somerset and Leicester Sound in Leicester, before being signed by Kent's Invicta FM in 1996. In 1997, he joined BRMB in Birmingham, presenting the shows Late & Live and Jezza's Jukebox.

In 2000, Kyle moved to the Century FM network, taking this format with him. The show was called Jezza's Confessions. It was broadcast between 9:00 pm and 1:00 am. He won a Sony Award for Late & Live in 2001. On 1 July 2002, he made his first broadcast on Virgin Radio, presenting Jezza's Virgin Confessions every weekday from 8pm to midnight. In mid-2003, he broadcast the show from 9pm to 1am every weekday, and in January 2004 the show went out from 10pm to 1am, Sunday to Thursday. He left Virgin Radio in June 2004. From 5 September 2004, Kyle presented the Confessions show on London's Capital FM. The new programme aired Sunday to Thursday from 10pm to 1am with live calls on relationship issues of all kinds. Capital Confessions came to an end on 22 December 2005 to make way for The Jeremy Kyle Show, a similar show which ran from January 2006 to December 2006.

Music Inc.

Music Inc. is an album by American jazz trumpeter Charles Tolliver's Music Inc. with a Big Band recorded in 1970 and first released on the Strata-East label.

Reception

The Allmusic review by Jason Ankeny awarded the album 4½ stars stating "The remarkable Music, Inc. Big Band remains the apotheosis of trumpeter Charles Tolliver's singular creative vision. Rarely if ever has a big band exhibited so much freedom or finesse, while at the same time never overwhelming the virtuoso soloists on whom the performances pivots".

Track listing

All compositions by Charles Tolliver except as indicated

Personnel