Secret (Heart song)

"Secret" is a song recorded by American rock band Heart. It was released as the fourth and final single from the band's tenth studio album Brigade.

The track is a rock power ballad which did not meet with much mainstream success, peaking at number sixty-four on the U.S. Billboard Hot 100 and number seventy-nine on the UK Singles Chart. As an emotional song, it portrays forbidden love and the tragedy that the situation is. The communication in this power-ballad is often linked to the still on and off relationship Ann maintains with ex-guitarist Roger Fisher.

Chart performance

References

External links

Secret (chocolate bar)

Secret was a chocolate bar that was manufactured by Nestlé during the 1980s and the 1990s that was popular in the UK. It consisted of a bird's nest-styled chocolate coating with a creamy mousse centre similar to the filling of a Walnut Whip. It was packaged in a gold-coloured wrapper with the product's name printed on it in purple and white.

A television advert for the product, first shown in 1990, and set in a 1940s mystery film style featured an elegant lady riding a train when a man rushes into her cabin and hands her a Secret bar saying, "guard this with your life". He then runs off to divert the two mysterious men who've been following him, but while he's away, the woman eats the secret bar because she couldn't resist such a delicious temptation. When the man returns to retrieve it, it's gone, because she had eaten it. At the end of the advert the words accompanied by a voice-over says, "You can't trust anyone to keep a Secret." The product was discontinued a couple of years later, due to high production costs and low volume of sales.

Secret (disambiguation)

A secret is information kept hidden.

Secret or The Secret may also refer to:

General uses

Brands and Products

Places

Ships

Film and television

Évisa

Évisa is a commune in the Corse-du-Sud department of France on the island of Corsica.

Population

See also

References

Mitochondrial antiviral-signaling protein

Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. Aggregated MAVS forms protease resistant prion-like aggregates that activate IRF3 dimerization.

Function

Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI. These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK) and IKKB (IKBKB; MIM 603258), which activate NFKB, or TBK1 and IKBKE (IKBKE), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNβ (IFNB1). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1). For RIGI, the intermediary protein is mitochondria-bound MAVS.