By Lia Timson and Nick Miller
At least six people have died and 20 more are fighting for life following a massive blaze at a 24-storey block of flats in London.
More than 200 firefighters and 40 fire engines were called to the 120-apartment Grenfell Tower, on the Lancaster West Estate, north Kensington, in the early hours of Wednesday. The estate is on Latimer Road, White City.
More than 70 people were treated in hospital for injuries and smoke inhalation. On Wednesday afternoon 20 were in critical care, an ambulance services officer said.
London Fire Commissioner Dany Cotton said she was "very sad to confirm there have been fatalities. I cannot say how many at this time. The cause of the fire is not known at this time."
A resident peers out of a window from a small section of the building that was not on fire on Wednesday morning.Credit: AP
She said it was an "unprecedented incident". "In 25 years I have never seen anything of this scale," she said.
Crews wearing extended breathing apparatus "have been working in extremely challenging and difficult conditions to rescue people and to bring this major fire under control", she said.
Several firefighters received minor injuries while fighting the fire.
One firefighter, Terry, said he had seen a colleague hit by someone who had jumped out of a window.
Terry said it was the biggest fire he had seen.
London fire as broadcast by the BBC.Credit: Screengrab
"We had to literally run (to the building) under riot shields" held by police, he said. "We were struggling."
The London Ambulance Service said it had taken 50 patients to five hospitals while police say a "number of people are being treated for a range of injuries", including smoke inhalation, as pictures showed flames shooting metres into the sky, engulfing most of the block.
Smoke and flames engulfed Grenfell Tower on Wednesday morning.Credit: Twitter/@kafianoor
The Guardian reported more than 200 people live in the block, which is part of a large housing estate.
A building resident told the BBC she woke when her son noticed fire outside the window. "We grabbed what we could - when we opened up the door we saw a lot of smoke," she said.
The fire was still burning as the sun came up on Wednesday morning. Credit: AP
By the time she and her son escaped the building its entire left side was on fire "from top to bottom" she said. The woman said there had recently been works on the gas supply to the building - at Christmas half the building had lacked gas supply.
She added that the fire department had come to check the building on the weekend. "They said it was fine - it's not fine," she said. She and another resident said there had been no central fire alarm in the building.
Smoke and flames rise from the building. Credit: AP
A witness told BBC radio "It's just an inferno. I can hear people screaming, 'Help me, help me,' but the building is too big."
As dawn broke, columns of thick black smoke continued to rise from the building and ash filled the air, as firefighters tackled the blaze from the ground.
The housing estate tower is White City.Credit: London Fire Brigade
Councillor Robert Atkinson of the Royal Borough of Kensington and Chelsea (RBKC) told the BBC there were "people unaccounted for". Hundreds of people lived in the building, he said.
Churches, mosques and community centres in the area had opened their doors to those fleeing the blaze, he said, which had also meant it was harder to co-ordinate.
"One of the questions we will be asking is why the fire alarm system didn't work," he said. "We had received assurances that the system was looked at and it was given the all-clear. There are very serious questions to be asked as to how this could have happened."
Several residents have said they had been previously advised to stay in their apartments in case of fire.
One, Michael, told the BBC they had been told "if ever there was an outbreak of fire you must stay in the premises, they're fireproofed for up to an hour and by then you would have been rescued".
"But if we had stayed in the flat we would have perished," he said adding he had escaped in his boxer shorts through smoky corridors carrying his daughter wrapped in a dressing gown.
"Everyone was in shock, everyone was fleeing, screaming," he said.
"The block was just going up, it was like pyrotechnics, it was just unbelievable how quick it was burning."
He said it started on the fourth floor - he lived on the seventh. Once outside he could see people still in the building screaming "get me out of here". People outside were shouting at firefighters to use more water on the fire as "there are people in there burning to death". He had seen a lot of people escape, he said.
Actor and writer Tim Downie, who lives about 600 metres away, said he feared the block could collapse.
"It's horrendous. The whole building is engulfed in flames. It's gone. It's just a matter of time before this building collapses.
"I just hope they have got everyone out. People have been bringing water, clothes, anything they've got to help, out to the cordon," Downie said.
"I have seen people coming out in their bedclothes - it's just very distressing."
The London Fire Brigade said the cause of the fire was not yet known. At 6.30am local time it said 30 adjacent flats have been evacuated by police.
"We are dealing with a really serious fire that spread throughout the building," a spokesman for the fire brigade told Reuters. "The crews are doing all that they possibly can to tackle this fire."
A witness told Reuters that she feared not all the residents had escaped. Some were evacuated in their pyjamas.
Fabio Bebber wrote on Twitter: "More screams for help as the fire spreads to another side of the building.
"We can see how quick the fire spreads via the external panels. It's unbearable hearing someone screaming for their lives at #grenfelltower."
George Clarke, who presents the Channel 4 TV show Amazing Spaces, told Radio 5 Live: "I'm 100 metres away and I'm absolutely covered in ash.
"It's so heartbreaking, I've seen someone flashing their torches at the top level and they obviously can't get out.
"The guys are doing an incredible job to try and get people out of that building, but it's truly awful," he said.
He later told the BBC he was "getting covered in ash, that's how bad it is".
"I'm 100 metres away and I'm absolutely covered in ash."
Andy Moore who works for the BBC said the whole tower block was alight and there were fears the building might collapse.