Cancer Research Foundation

The Cancer Research Foundation is a tax-exempt, Public Charity based in the United States created exclusively to raise funds to further and support cancer research. The foundation is designed to minimize operating expenses and to donate a hundred percent of all net proceeds to cancer research.

The Cancer Research Foundation supports the research efforts of a select group of top institutes on the cutting edge of cancer research. consciously supporting diverse and innovative centers in the expectation that each institute will find a different piece to the puzzle and that, together, will find a cure or cures to more than 200 types of cancer.

See also

Cancer research

Cancer research is basic research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure.

Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatment. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, Immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy.

Areas of research

Cause

Early research on the cause of cancer was summarized by Haddow in 1958. The first chemical carcinogen was identified in 1928-29 as 1:2-5:6-dibenzanthracene, and the carcinogeneic substance in pitch was identified as 3:4-benzopyrene in 1933. Haddow concluded that “there can be little doubt of the importance of their [chemical] combination with the genetical material” as the source of the chemical mechanism of action of carcinogens. Brookes and Lawley, in 1964, summarized ongoing research into the causes of cancer. They referred to the competing hypotheses that carcinogens reacted mainly with proteins versus mainly with DNA. The direct research of Brookes and Lawley, testing carcinogenic hydrocarbons, indicated that they react with DNA. McCann et al. in 1975 and McCann and Ames, in 1976, tested 175 known carcinogens for interaction with DNA sufficient to cause mutations in their new Salmonella/microsome test. This test uses bacteria as sensitive indicators of DNA damage. They found that 90% of known carcinogens caused mutations in their test. They indicated that the carcinogens that did not cause mutations in their assay were likely due to the need for the carcinogens to be activated by enzymes not available in their system.

Cancer Research (journal)

Cancer Research is a peer-reviewed scientific journal published by the American Association for Cancer Research. It covers research on all aspects of cancer and cancer-related biomedical sciences and was established in 1941. The editor-in-chief is George C. Prendergast (Lankenau Institute for Medical Research). The journal was established in 1916 as the Journal of Cancer Research, was renamed American Journal of Cancer in 1931, and obtained its current name in 1941.

Abstracting and indexing

The journal is abstracted and indexed in:

According to the Journal Citation Reports, the journal has a 2014 impact factor of 9.329, ranking it 11th out of 211 journals in the category "Oncology".

References

External links