Eric Lander

Eric Steven Lander (born February 3, 1957), a mathematician and geneticist, is a Professor of Biology at the Massachusetts Institute of Technology (MIT), former member of the Whitehead Institute, and founding director of the Broad Institute of MIT and Harvard who has devoted his career to realizing the promise of the human genome for medicine. He is co-chair of U.S. President Barack Obama's Council of Advisors on Science and Technology.

Early life and education

Lander was raised in a Jewish family, the son of Harold and Rhoda Lander who were both lawyers. He was captain of the math team at Stuyvesant High School and an International Mathematical Olympiad Silver Medalist for the United States, graduating from high school in 1974. At the age of seventeen, he wrote a paper on quasiperfect numbers for which he won the Westinghouse Prize.

Lander attended Princeton University, where he graduated in 1978 as valedictorian. He then attended the University of Oxford as a Rhodes Scholar, and he wrote his doctoral D.Phil. thesis on algebraic coding theory and symmetric block designs, under the supervision of Peter Cameron.

Lander

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Eric

The given name Eric, Erik, or Erick is derived from the Old Norse name Eiríkr (or Eríkr in Eastern Scandinavia due to monophthongization). The first element, ei- is derived either from the older Proto-Norse *aina(z) meaning "one" or "alone" or from Proto-Norse *aiwa(z) meaning "ever" or "eternal". The second element -ríkr derives either from *rík(a)z meaning "ruler" or "prince" (cf. Gothic reiks) or from an even older Proto-Germanic *ríkiaz which meant "powerful" and "rich". The name is thus usually taken to mean "one ruler", "autocrat", "eternal ruler" or "ever powerful", "warrior", and "government".

The most common spelling in Scandinavia is Erik. In Norway, another form of the name (which has kept the Old Norse diphthong) Eirik is also commonly used. In Finland, the form Erkki is also used. The modern Icelandic version is Eiríkur, while the modern Faroese version is Eirikur. Éric [eʁik] is used in French, and in Germany Eric, Erik and Erich are used.

Although the name was in use in Anglo-Saxon England, its use was reinforced by Scandinavian settlers arriving before the Norman Invasion. It was an uncommon name in England until the Middle Ages, when it gained popularity, and finally became a common name in the 19th century. This was partly because of the publishing of the novel Eric, or, Little by Little by Frederick William Farrar in 1858.

Human genome

The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos.

The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.

Broad Institute

The Eli and Edythe L. Broad Institute of MIT and Harvard (/ˈbroʊd/), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and is partners with Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals.

History

The Broad Institute, formerly the Broad Institute of MIT and Harvard, evolved from a decade of research collaborations among MIT and Harvard scientists. One cornerstone was the Center for Genome Research of Whitehead Institute at MIT. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and human genetics. Another cornerstone was the Institute of Chemistry and Cell Biology established by Harvard Medical School in 1998 to pursue chemical genetics as an academic discipline. Its screening facility was one of the first high-throughput resources opened in an academic setting. It facilitated small molecule screening projects for more than 80 research groups worldwide.