Vicky Karayiannis, the wife of Soundgarden frontman Chris Cornell, has released a heartbreaking statement following the release of the toxicology report on Friday.
The report revealed the singer had several prescription drugs in his system when he took his own life last month in a Detroit hotel.
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Video surfaces of Chris Cornell's last performance
Audioslave and Soundgarden frontman Chris Cornell died on Wednesday night in Detroit. He was 52.
Cornell, 52, had anti-anxiety drugs, sedatives, barbiturates and sinus congestion medication in his system.
The medical examiner last month determined that the grunge singer took his own life on May 17 in his hotel bathroom.
He was found dead hours after playing a concert in Detroit with the band.
Cornell had spoken openly in interviews of his struggles with drugs as a teenager and later with alcohol.
But he said in 2007 that he had been sober since checking himself into rehab in 2002. He also spoke of periods of depression and agoraphobia.
Karayiannis has said her husband could not have been in his right mind when he died, saying his judgment may have been impaired by taking anti-anxiety drugs.
"Many of us who know Chris well noticed that he wasn't himself during his final hours and that something was very off," Karayiannis said in a statement released on Friday. "We have learned from this report that several substances were found in his system."
"After so many years of sobriety, this moment of terrible judgement seems to have completely impaired and altered his state of mind," Karayiannis continued. "Something clearly went terribly wrong and my children and I are heartbroken and are devastated that this moment can never be taken back."
She also thanked fans for their support.
"We very much appreciate all of the love we have received during this extremely difficult time and are dedicated to helping others in preventing this type of tragedy."
In an initial statement after his death, Karayiannis said she was concerned about her husband on the day of his death.
"When we spoke after the show, I noticed he was slurring his words; he was different," Karayiannis said. "When he told me he may have taken an extra Ativan or two, I contacted security and asked that they check on him."
She said it was "a loss that escapes words and has created an emptiness in my heart that will never be filled".
"As everyone who knew him commented, Chris was a devoted father and husband," said Karayiannis. "He was my best friend."
Fairfax Media with Reuters