- published: 27 Mar 2015
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Aubrey David Nicholas Jasper de Grey (/dəˈɡreɪ/; born 20 April 1963) is an English author and biomedical gerontologist, currently the Chief Science Officer of the SENS Research Foundation. He is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is known for his view that medical technology may enable human beings alive today to live indefinitely.
De Grey's research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.
De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies. He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time and the Skeptics' Guide to the Universe. He is also a member of Flooved advisory Board.
Senescence (/sɪˈnɛsəns/) (from Latin: senescere, meaning "to grow old," from senex) or biological aging (also spelled biological ageing) is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation. The word "senescence" can refer either to cellular senescence or to senescence of the whole organism. It is commonly believed that cellular senescence underlies organismal senescence. The science of biological aging is biogerontology.
Senescence is not the inevitable fate of all organisms and can be delayed. The discovery, in 1934, that calorie restriction can extend lifespan twofold in rats, and the existence of species having negligible senescence and potentially immortal species such as Hydra, have motivated research into delaying and preventing senescence and thus age-related diseases. Organisms of some taxonomic groups (taxa), including some animals, even experience chronological decrease in mortality, for all or part of their life cycle. On the other extreme are accelerated aging diseases, rare in humans. There is also the extremely rare and poorly understood "Syndrome X," whereby a person remains physically and mentally an infant or child throughout one's life.
Khan Academy is a non-profit educational organization created in 2006 by educator Salman Khan with the aim of providing a free, world-class education for anyone, anywhere. The organization produces short lectures in the form of YouTube videos. In addition to micro lectures, the organization's website features practice exercises and tools for educators. All resources are available for free to anyone around the world. The main language of the website is English, but the content is also available in other languages.
The founder of the organization, Salman Khan, was born in New Orleans, Louisiana, United States to immigrant parents from Bangladesh and India. After earning three degrees from the Massachusetts Institute of Technology (a BS in mathematics, a BS in electrical engineering and computer science, and an MEng in electrical engineering and computer science), he pursued an MBA from Harvard Business School.
In late 2004, Khan began tutoring his cousin Nadia who needed help with math using Yahoo!'s Doodle notepad.When other relatives and friends sought similar help, he decided that it would be more practical to distribute the tutorials on YouTube. The videos' popularity and the testimonials of appreciative students prompted Khan to quit his job in finance as a hedge fund analyst at Connective Capital Management in 2009, and focus on the tutorials (then released under the moniker "Khan Academy") full-time.
Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the "process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs via stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs.
Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and safely implanting them when the body cannot heal itself. If a regenerated organ's cells would be derived from the patient's own tissue or cells, this would potentially solve the problem of the shortage of organs available for donation, and the problem of organ transplant rejection.
The term "regenerative medicine" was first found in a 1992 article on hospital administration by Leland Kaiser. Kaiser’s paper closes with a series of short paragraphs on future technologies that will impact hospitals. One paragraph had ‘‘Regenerative Medicine’’ as a bold print title and stated, ‘‘A new branch of medicine will develop that attempts to change the course of chronic disease and in many instances will regenerate tired and failing organ systems.’’
Tim Eliot, better known by his stage name Current Value, is a German drum & bass producer and DJ.
With substantial training in classical piano, Eliot began dabbling in electronic music in 1992, when he got a Casio keyboard for Christmas. Several years later he began receiving recognition on local Berlin radio stations.
In 2004, after 1 year of education, he received his Diploma at the School of Audio Engineering (SAE).
In 2012, his remix of a track from Björk's album Biophilia, was included on Biophilia Remix Series I.
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Created by Vishal Punwani. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/cells/cellular-development/v/cellular-movement?utm_source=YT&utm;_medium=Desc&utm;_campaign...
Dr. Judith Campisi, a professor at the Buck Institute for Research on Aging, focuses her lecture on senescent cells and their role in cancer and aging. She explains how cancer is an age-related disease by describing the many conditions beyond DNA mutations that must generally be met for a malignant tumor to form. Dr. Campisi acknowledges that while cellular senescence is a powerful anti-cancer mechanism and while senescent cells may even play a key role in wound healing, senescent cells can nonetheless cause inflammation in their local environment and actually support the formation of tumors. Visit www.sens.org/videos to view the rest of our course lecture videos.
What is SENESCENCE? What does SENESCENCE mean? SENESCENCE meaning - SENESCENCE pronunciation - SENESCENCE definition - SENESCENCE explanation - How to pronounce SENESCENCE? Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. Senescence is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation. The word "senescence" can refer either to cellular senescence or to senescence of the whole organism. It is commonly believed that cellular senescence underlies organismal senescence. The science of biological aging is biogerontology. Senescence is not the inevitable fate of all organisms and can be delayed. The...
Botany Paper-V Plant Physiology, Biochemistry and Biotechnology
Dr. Rhonda Patrick interviews Dr. Judith Campisi, a professor of biogerontology at the Buck Institute for Research on Aging, a co-editor in chief of the Aging Journal and an expert on the role of cellular senescence in the aging process and development of cancer. Cellular senescence is so important when we discuss aging and cancer because as our cells accumulate damage, which naturally happens as we age (even as a consequence of the energy generating processes and immune cell activation), there's only so many outcomes that we can expect. The first possibility is that the cells can die. The next is that they can become senescent where they stop dividing but stay alive all-the-while secreting molecules that influence surrounding tissue… or the worst of all possible outcomes, the cells can r...
Big collab on a big album! Check out Current Value’s new LP ‘Biocellulose’, which represents only the darkest styles of Drum & Bass! Out on Critical Music. Buy ‘Biocellulose’: Beatport: https://pro.beatport.com/release/biocellulose/1724878 iTunes: https://itunes.apple.com/us/album/biocellulose/id1089891682 Juno Download: http://www.junodownload.com/products/current-value-biocellulose/3049226-02 Follow Current Value: Facebook: https://www.facebook.com/currentvalue Soundcloud: https://soundcloud.com/tim-e-aka-current-value Follow Mefjus: Facebook: http://www.facebook.com/mefjus Soundcloud: https://soundcloud.com/mefjus Follow Critical Music: Facebook: https://www.facebook.com/criticalmusic Soundcloud: https://soundcloud.com/critical-music More from Biocellulose: - Footwork: https://www....
Video shows what senescence means. The state or process of ageing, especially in humans; old age.. Ceasing to divide by mitosis because of shortening of telomeres or excessive DNA damage.. Old age; accumulated damage to macromolecules, cells, tissues and organs with the passage of time.. Senescence Meaning. How to pronounce, definition audio dictionary. How to say senescence. Powered by MaryTTS, Wiktionary
We’d like to thank Focus Features for sponsoring this video – and for inviting us to pre-screen their summer 2015 film “Self/Less”. It’s a sci-fi flick that explores memory, consciousness, and immortality, and it made us think about the types of immortality that already exist here on Earth. A big thanks to Focus Features for supporting MinuteEarth! http://www.focusfeatures.com/selfless Thanks also to our Patreon patrons: - Today I Found Out - Jeff Straathof - Maarten Bremer - Mark - BurmansHealthShop - Alberto Bortoni - Avi Yashchin - Valentin - Nicholas Buckendorf - Antoine Coeur YOU can also support us on Patreon: https://www.patreon.com/minuteearth ___________________________________________ Want to learn more about the topic in this week’s video? Here are some key words/ph...
Time-lapse video of a forest undergoing seasonal change. For a more detailed description please refer to my educational website: http://www.iecology.net/tl_forest.html. This was a joint project with Sam Orr.
During the course of tumor progression, cancer cells aquire a number of characteristic alterations. These include the capacities to proliferate independently of exogenous growth-promoting or growth-inhibitory signals, to invade surrounding tissues and metastasize to distant sites, to elicit an angiogenic response, and to evade mechanisms that limit cell proliferation, such as apoptosis and replicative senescence. These properties reflect alterations in the cellular signalling pathways that in normal cells control cell proliferation, motility, and survival. http://www.polygonmedical.com/oncology.html For more info visit: www.polygonmedical.com
Senescence, or ageing, describes the decline in longevity and fertility suffered by all organisms as they age. According to evolutionary theory senescence is caused by relaxed Darwinian selection acting at old age, and can fuel fierce evolutionary conflict, including conflict between reproductive partners (sexual conflict). The focus my D. Phil., which I recently completed (Nov 2009) at the Department of Zoology of the University of Oxford (UK), has been to investigate how reproductive senescence suffered by males impacts on the reproductive success of their partners, in an avian model system, the fowl, Gallus gallus domesticus. Our dance depicts the evolutionary sexual battle between ageing roosters and hens. The scene is set in a bar – the arena for sexual selection in humans. The sex...
Aubrey de Grey received his BA, MA and PhD degrees from the University of Cambridge, Cambridge, UK, where he was formerly a research associate. He is chairman and chief science officer of the Methuselah Foundation and editor-in-chief of the academic journal Rejuvenation Research. His main research areas are the role and etiology of oxidative damage in mammalian aging, including both mitochondrial and extracellular free radical production and damage, and the design of interventions to reverse the age-related accumulation of oxidative and other damage. He is author of the book Ending Aging (2007) and subject of the British Channel 4 documentary Do You Want to Live Forever? (2007). He has developed a comprehensive plan, termed Strategies for Engineered Negligible Senescence (SENS), which brea...
Dr. Laura Briggs is the Director of Cell Biology at Sierra Sciences in Reno, Nevada. She earned her Ph.D. in Environmental Science and Health at the University of Nevada. Dr. Briggs joined Sierra Sciences in 2001, where she leads a team investigating approaches to transiently activate the expression of telomerase. One basic quality of human life is that every time our cells divide the tips of our chromosomes get shorter. This shortening of telomeres may be the molecular clock of aging. Indeed, the shortening of telomeres has been shown to be the trigger that induces senescence of human cells grown in culture; whether this can be extrapolated to include human organismal aging itself is not yet known. The correlation between telomere length and age is very strong and shorter telomeres di...
Join us for a fascinating discussion with Dr. Aubrey de Grey, Chief Science officer of the SENS Foundation (SENS stands for “Strategies for Engineered Negligible Senscence”), on the topic of “Regenerative Medicine Against Aging.” Dr. de Grey has been a provocative and polarizing figure in the scientific and medical communities’ dialogue on the topic of life extension, and the approaches that will lead to dramatic increases in quantity and quality of life. According to Dr. de Grey, “the first human who will live up to 1,000 years is probably already alive now, and might even be today between 50 and 60 years old.” Biography: Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK, and is the Chief Science Officer of SENS Foundation, a California-based 501(c)(3) charity de...
Join us for a fascinating discussion with Dr. Aubrey de Grey, Chief Science officer of the SENS Foundation (SENS stands for “Strategies for Engineered Negligible Senscence”), on the topic of “Regenerative Medicine Against Aging.” Dr. de Grey has been a provocative and polarizing figure in the scientific and medical communities’ dialogue on the topic of life extension, and the approaches that will lead to dramatic increases in quantity and quality of life. According to Dr. de Grey, “the first human who will live up to 1,000 years is probably already alive now, and might even be today between 50 and 60 years old.” Biography: Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK, and is the Chief Science Officer of SENS Foundation, a California-based 501(c)(3) charity de...
The Sensory Cottage By Rachel Ward Visual/Sensory Ethnography Project 26 minutes Represented Themes: Animism Embodiment Kinship Life Cycles Endeavored Constructions: Cottage as animate Cottage as person Cottage as kin Cottage as the universe Resultant formulaic: Parallel life cycle between myself, the cottage and the universe Questions considered: • Can the cottage be a person (if defined within the context of the Ojibwa worldview)? • Can the cottage and I have a notion of kinship (as based on notions of “collective memories” and contexts of personhood in Obijwa ontology)? • If the cottage is a “person,” does it have a biography? • Is there a reciprocal “making” of biographies between myself and the cottage (cf., Ingold 2000)? Between the cottage and the universe? Between m...
Dr. Aubrey de Grey is Chairman and Chief Science Officer of The Methuselah Foundation. His major research interests are the role and etiology of all forms of cellular and molecular damage in mammalian aging, and the design of interventions to reverse the age-related accumulation of such damage. He has published extensively on these and other areas of gerontology, and is also Editor-in-Chief of the high-impact journal Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging. He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organizer of an ongoing series of conferences and workshops th...
Aubrey de Grey (GB), Chief Science Officer & Co-Founder, SENS Research Foundation Topic Leader: Stephen Sackur (GB) Presenter HARDtalk, BBC Broadcasting House
Hello friends, welcome to Avatar Technology Digest / Extra. Today we are lucky to introduce you to an intriguing figure such as Aubrey de Grey, the British researcher who claims to have drawn a roadmap to defeat biological aging. He provocatively proposes that the first human beings who will live to 1,000 years old have already been born. Aubrey de Grey is the man who is convinced that only the lack of proper funding separates us from the final victory over the aging. He is the Co-founder and Director of Science of SENS Research Foundation, the organization that develops methods to combat aging. In addition, de Grey is the author of «Ending Aging», the book that discusses the possibility of a complete medical victory over the aging in the next few decades. By Olesya Yermakova With the ...
Interviewer - LEAF/Lifespan.io Board member Elena Milova. Support Aubrey de grey with SENS here: http://www.sens.org Subscribe for video's about talks with: - Ray Kurzweil - Lawrence krauss - Michio Kaku - Aubrey de Grey - Brian Greene - Neil deGrasse Tyson - Richard Dawkins - Elon Musk - And many more
Can we live to 1,000? It was outrageous when he said it at ideacity in 2008… and again in 2015. Now he’s back to update us on the incredible progress that has been made toward life extension. Michael Kramer of Zoomer Radio talks with Aubrey de Grey at ideacity 2017. Aubrey de Grey is an English author and biomedical gerontologist, currently the Chief Science Officer of the SENS Research Foundation.
Source: http://www.riskmindslive.com/will-rea... Is ageing a disease? Can it be cured? Can death be pushed back? Will you live to 1000 years? Aubrey de Grey, Chief Science Officer, SENS Research Foundation divulges the truth behind longevity and the ensuing risks and discover how you should transform your life insurance models. He spoke to Markus Salchegger, Managing Director at Accenture Risk & Finance at RiskMinds Insurance 2016, Amsterdam. Website: http://sens.org YouTube: https://www.youtube.com/user/SENSFVideo Facebook: https://www.facebook.com/sensf Aubrey de Grey: http://goo.gl/Tc5QHl Aubrey de Grey (GB), Chief Science Officer & Co-Founder, SENS Research Foundation. Aubrey David Nicholas Jasper de Grey is an English author and theoretician in the field of gerontology and the Chi...
Dr. Aubrey de Grey, Biomedical Gerontologist FULL EPISODE: https://londonrealacademy.com/episodes/aubrey-de-grey-how-to-live-forever/ Aubrey de Grey is a true frontiersman, daring to push out against what seems the most natural and unstoppable forces of nature - ageing. He’s not just another voice though, he’s a scientist and identifies ageing as a disease, one that can be cured with the right medicine. His work calls for serious scientific exploration of what causes tissue to age and to then find solutions to those components - what he calls the roadmap to defeat biological ageing. In fact, he believes that the first humans who will live to be 1,000 years old are already alive today! Ageing, and indeed death, are some of the most colossal challenges to humanity biologically and philosop...
Aubrey de Grey talking about tackling most important and hard but not impossible to solve problems as a visionary entrepreneur. Interview on how to overcome the obstacles of aging, how to adapt our minds to new realities and the importance of being a great communicator with Myriam Locher, Founder of Bettermind.
http://en.wikipedia.org/wiki/Aubrey_De_Grey Imagine life without aging. You could live for hundreds of years with the mental and physical attributes of your 25 year old self. Would you be tempted? HARDtalk speaks to a scientist and futurologist who believes it is a proposition that 21st century biotechnology will soon be able to deliver. Aubrey de Grey's Californian research foundation is spending millions of dollars in a bid to conquer the aging process. Is his vision inspiring, daft, or downright dangerous?
Full Interview: http://tinyurl.com/p93xfuc Website: http://www.sens.org Aubrey de Grey: http://tinyurl.com/7knmonn Aubrey de Grey (GB), Chief Science Officer & Co-Founder, SENS Research Foundation. Aubrey David Nicholas Jasper de Grey is an English author and theoretician in the field of gerontology and the Chief Science Officer of the SENS Research Foundation. He is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is known for his view that medical technology may enable human beings alive today to live to lifespans far in excess of any existing authenticated cases. De Grey's research focuses on whether regenerative medicine can thwart the aging process. He works on the...