Epidemic

An epidemic (from Greek ἐπί epi "upon or above" and δῆμος demos "people") is the rapid spread of infectious disease to a large number of people in a given population within a short period of time, usually two weeks or less. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic.

Epidemics of infectious disease are generally caused by several factors including a change in the ecology of the host population (e.g. increased stress or increase in the density of a vector species), a genetic change in the pathogen reservoir or the introduction of an emerging pathogen to a host population (by movement of pathogen or host). Generally, an epidemic occurs when host immunity to either an established pathogen or newly emerging novel pathogen is suddenly reduced below that found in the endemic equilibrium and the transmission threshold is exceeded.

An epidemic may be restricted to one location; however, if it spreads to other countries or continents and affects a substantial number of people, it may be termed a pandemic. The declaration of an epidemic usually requires a good understanding of a baseline rate of incidence; epidemics for certain diseases, such as influenza, are defined as reaching some defined increase in incidence above this baseline. A few cases of a very rare disease may be classified as an epidemic, while many cases of a common disease (such as the common cold) would not.

United States

Coordinates: 40°N 100°W / 40°N 100°W / 40; -100

The United States of America (USA), commonly referred to as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major territories and various possessions. The 48 contiguous states and Washington, D.C., are in central North America between Canada and Mexico. The state of Alaska is in the northwestern part of North America and the state of Hawaii is an archipelago in the mid-Pacific. The territories are scattered about the Pacific Ocean and the Caribbean Sea. At 3.8 million square miles (9.842 million km²) and with over 320 million people, the country is the world's third or fourth-largest by total area and the third most populous. It is one of the world's most ethnically diverse and multicultural nations, the product of large-scale immigration from many countries. The geography and climate of the United States are also extremely diverse, and the country is home to a wide variety of wildlife.

Last Week Tonight with John Oliver

Last Week Tonight with John Oliver, often abridged as Last Week Tonight, is an American late-night talk and news satire television program airing on Sundays on HBO in the United States and HBO Canada, and on Mondays (originally Tuesdays) on Sky Atlantic in the United Kingdom. The half-hour long show premiered on Sunday, April 27, 2014, and is hosted by comedian John Oliver. Last Week Tonight shares some similarities with Comedy Central's The Daily Show with Jon Stewart, where Oliver was previously featured as a correspondent and fill-in host, as it takes a satirical look at news, politics and current events on a weekly basis.

Oliver has said that he has full creative freedom, including free rein to criticize corporations. His initial contract with HBO was for two years with an option for extension. In February 2015, it was announced that the show has been renewed for two additional seasons of 35 episodes each. Oliver and HBO programming president Michael Lombardo have discussed extending the show from half an hour to a full hour and airing more than once a week after Oliver "gets his feet under him".

Cleveland Clinic

The Cleveland Clinic is a multispecialty academic hospital located in Cleveland, Ohio that is owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation established in 1921. In addition to their flagship hospital in Cleveland, Cleveland Clinic also operates affiliated facilities in Florida, Nevada, Canada, and Abu Dhabi.

History

Early beginnings

Cleveland Clinic grew out of the surgical practice of Frank J. Weed (died 1891) at 16 Church Street on the near west side of Cleveland. The practice was purchased by his two assistants, Frank E. Bunts and George Washington Crile. In 1892 they brought Crile's cousin, William E. Lower into the practice. In 1897 they moved to the Osborn Building on Prospect Avenue in downtown Cleveland. Crile, Lower and Bunts became professors at Cleveland medical schools, and each would be elected president of the Academy of Medicine.

Crile organized the American military hospital in Paris in 1915, and later led the United States Army Base Hospital No. 4, in Rouen, France. It was the first contingent of the United States Army to see active duty in Europe during the First World War. Bunts and Lower also served in the Rouen hospital. In his autobiography, Crile reports that, while in France, the three doctors discussed starting a new medical center in Cleveland upon their return.