Morris Island is an 840 acre (3.4 km²) uninhabited island in Charleston Harbor in South Carolina, accessible only by boat. The island lies in the outer reaches of the harbor and was thus a strategic location in the American Civil War.

Morris Island was heavily fortified to defend Charleston harbor, with the fortifications centered on Fort Wagner. It was the scene of heavy fighting during the Union Army's campaign to capture Charleston, and is perhaps best known today as the scene of the ill-fated assault by the 54th Massachusetts Volunteer Infantry, an African-American regiment. The regiment and this assault, where it suffered over 50% casualties, was immortalized in the film Glory.

After the Confederates abandoned Morris Island in 1863, the Union occupied it and transferred 520 Confederate officers from Fort Delaware to Morris Island. They were used as Human Shields in an attempt to silence the Confederate artillery at Fort Sumter and soon became known in the South as the Immortal Six Hundred. This was done by the Union when it was learned that the Confederacy had a similar number of human shields in Charleston to deter Union ships from firing on the city. Land Erosion has destroyed a great deal of the old fortifications on the island, including some parts of Fort Wagner.