OLIG1

OLIG1
Identifiers
Aliases	OLIG1, BHLHB6, BHLHE21, oligodendrocyte transcription factor 1
External IDs	MGI: 1355334 HomoloGene: 9667 GeneCards: OLIG1
Gene ontology Molecular function • DNA binding • protein binding • protein dimerization activity Cellular component • nucleus Biological process • multicellular organism development • neuron fate commitment • oligodendrocyte differentiation • regulation of transcription, DNA-templated • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	116448	50914
Ensembl	ENSG00000184221	ENSMUSG00000046160
UniProt	Q8TAK6	Q9JKN5
RefSeq (mRNA)	NM_138983	NM_016968
RefSeq (protein)	NP_620450	NP_058664.2
Location (UCSC)	Chr 21: 33.07 – 33.07 Mb	Chr 16: 91.27 – 91.27 Mb
PubMed search
Wikidata
View/Edit Human		View/Edit Mouse

Oligodendrocyte transcription factor 1 is a protein that in humans is encoded by the OLIG1 gene.

Further reading

• Zhou Q, Wang S, Anderson DJ (Feb 2000). "Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors". Neuron. 25 (2): 331–43. doi:10.1016/S0896-6273(00)80898-3. PMID 10719889. 
• Takebayashi H, Yoshida S, Sugimori M, Kosako H, Kominami R, Nakafuku M, Nabeshima Y (Dec 2000). "Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3". Mechanisms of Development. 99 (1-2): 143–8. doi:10.1016/S0925-4773(00)00466-4. PMID 11091082. 
• McLellan AS, Langlands K, Kealey T (Dec 2002). "Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening". Gene Expression Patterns. 2 (3-4): 329–35. doi:10.1016/S0925-4773(02)00390-8. PMID 12617822. 
• McLellan AS, Langlands K, Kealey T (Dec 2002). "Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening". Mechanisms of Development. 119 Suppl 1: S285–91. doi:10.1016/S0925-4773(03)00130-8. PMID 14516699. 
• Arnett HA, Fancy SP, Alberta JA, Zhao C, Plant SR, Kaing S, Raine CS, Rowitch DH, Franklin RJ, Stiles CD (Dec 2004). "bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS". Science. 306 (5704): 2111–5. doi:10.1126/science.1103709. PMID 15604411. 
• Jakovcevski I, Zecevic N (Nov 2005). "Olig transcription factors are expressed in oligodendrocyte and neuronal cells in human fetal CNS". The Journal of Neuroscience. 25 (44): 10064–73. doi:10.1523/JNEUROSCI.2324-05.2005. PMID 16267213. 
• Goris A, Yeo TW, Maranian M, Walton A, Ban M, Gray J, Compston A, Sawcer S (Nov 2006). "Novel Olig 1-coding variants and susceptibility to multiple sclerosis". Journal of Neurology, Neurosurgery, and Psychiatry. 77 (11): 1296–7. doi:10.1136/jnnp.2006.090639. PMC 2077377. PMID 16820418. 
• Ruf N, Martelli M, Weschke B, Uhlenberg B (Apr 2007). "Oligodendroglial transcription factor (OLIG1 and OLIG2) mutations are not associated with Pelizaeus-Merzbacher-like leukodystrophy". American Journal of Medical Genetics Part B. 144B (3): 365–6. doi:10.1002/ajmg.b.30434. PMID 17171653. 
• Brena RM, Morrison C, Liyanarachchi S, Jarjoura D, Davuluri RV, Otterson GA, Reisman D, Glaros S, Rush LJ, Plass C (Mar 2007). "Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer". PLoS Medicine. 4 (3): e108. doi:10.1371/journal.pmed.0040108. PMC 1831740. PMID 17388669. 

External links

• OLIG1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.