A groundbreaking international study is seeking Canberra volunteers to help unravel the genetic triggers of depression.
Believed to be the largest depression research project ever undertaken, the study is aiming to survey 200,000 participants across the globe in the next two years.
Australian researchers collaborating on the Genetics of Depression Study are hoping to contribute 10 per cent of this sample, or 20,000 participants.
Lead investigator Professor Nick Martin, from the Queensland Institute of Medical Research, said the study could revolutionise the way depression is diagnosed and treated.
"We are aiming to identify genetic factors that influence why various treatments for clinical depression are successful for some people, but not for others," he said.
"Identification of the genes that predispose people to clinical depression could revolutionise future research into causes, treatment and prevention of the illness."
The study is seeking volunteers aged 18 and older who either are being treated for clinical depression, or have been treated for it in the past.
Clinical depression is a complex illness that is caused by a combination of factors such as genetics and lifestyle.
At least one in seven Australians will experience clinical depression throughout their lifetime.
Professor Ian Hickie AM, from the University of Sydney, said there was still a huge knowledge gap regarding the genetic causes of depression.
"That's why we need Australian adults who have, or are continuing to be treated for clinical depression by a doctor, psychologist or psychiatrist," he said.
"[Participants who] understand how disabling and potentially life threatening this illness can be, to help us find the genetic causes."
The study requires volunteers to complete a quick online survey, with some then asked to provide saliva samples for DNA testing.
"Study volunteers will be making a genuine contribution to better understanding, and helping us to solve this devastating illness," Professor Hickie said.
Jennifer, 32, is one of the Canberra volunteers hoping to make a difference by contributing to the study.
"This study could help me find ways to prevent the onset of depression," she said.
To find out more about the Genetics of Depression Study visit: www.geneticsofdepression.org.au