Ethylone
![]() |
|
Clinical data | |
---|---|
Pregnancy category |
|
Routes of administration |
Oral, nasal, IV |
Legal status | |
Legal status |
|
Identifiers | |
|
|
CAS Number | 1112937-64-0 ![]() |
PubChem (CID) | 57252245 |
ChemSpider | 21106271 ![]() |
UNII | L91C78FW96 ![]() |
Chemical and physical data | |
Formula | C12H15NO3 |
Molar mass | 221.2524 g/mol |
3D model (Jmol) | Interactive image |
Chirality | Racemic mixture |
|
|
|
|
![]() ![]() |
Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, βk-MDEA), is recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone.[citation needed] In the United States, it began to be found in cathinone products in late 2011.[1]
Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, but several ethylone-related deaths have been reported.[1]
Pharmacokinetics[edit]
Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[2]
- N-deethylation to the primary amine.
- Reduction of the keto moiety to the respective alcohol.
Legal Status[edit]
As of October 2015 Ethylone is a controlled substance in China.[3]
See also[edit]
References[edit]
- ^ a b Dayong Lee; Chris W. Chronister; Jennifer Hoyer; Bruce A. Goldberger (September 2015). "Ethylone-Related Deaths: Toxicological Findings". Journal of Analytical Toxicology. 39 (7): 567–571. doi:10.1093/jat/bkv053. PMID 26025164.
- ^ Meyer, Markus R; Jens Wilhelm; Frank T. Peters; Hans H. Maurer (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry. 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362.
- ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.
External links[edit]
Phenylalkyl- amines (other than cathinones) |
|
---|---|
Cyclized phenyl- alkylamines |
|
Cathinones | |
Tryptamines | |
Chemical classes |
Adamantanes | |
---|---|
Adenosine antagonists | |
Alkylamines | |
Ampakines | |
Arylcyclohexylamines | |
Benzazepines | |
Cholinergics |
|
Convulsants | |
Eugeroics | |
Oxazolines | |
Phenethylamines |
|
Phenylmorpholines | |
Piperazines | |
Piperidines |
|
Pyrrolidines | |
Racetams | |
Tropanes |
|
Tryptamines | |
Others |
|
α1 |
|
||||||
---|---|---|---|---|---|---|---|
α2 |
|
||||||
β |
|
||||||
Phenethylamines |
|
---|---|
Amphetamines |
|
Phentermines |
|
Cathinones |
|
Phenylisobutylamines | |
Phenylalkylpyrrolidines | |
Catecholamines (and close relatives) |
|
Miscellaneous |
|
![]() |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
- CS1 Chinese-language sources (zh)
- Articles with changed CASNo identifier
- Articles with changed ChemSpider identifier
- Articles with changed FDA identifier
- Articles with changed InChI identifier
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Drugboxes with an unspecified ATC code
- Drugboxes which contain changes to verified fields
- Drugboxes which contain changes to watched fields
- All articles with unsourced statements
- Articles with unsourced statements from May 2015
- All stub articles