Baeocystin
 |
|
 |
|
| Clinical data | |
|---|---|
| Routes of administration |
Oral |
| ATC code | none |
| Legal status | |
| Legal status |
|
| Identifiers | |
|
|
| CAS Number | 21420-58-6  |
| PubChem (CID) | 161359 |
| ChemSpider | 141741 |
| Chemical and physical data | |
| Formula | C11H15N2O4P |
| Molar mass | 270.222 g/mol |
| 3D model (Jmol) | Interactive image |
|
|
|
|
| (verify) | |
Baeocystin is a psilocybin mushroom alkaloid and analog of psilocybin. It is found as a minor compound in most psilocybin mushrooms together with psilocybin, norbaeocystin, and psilocin. Baeocystin is an N-demethylated derivative of psilocybin, and a phosphorylated derivative of 4-HO-NMT (4-hydroxy-N-methyltryptamine). The structures at right illustrate baeocystin in its zwitterionic form.
Baeocystin was first isolated from the mushroom Psilocybe baeocystis,[1] and later from P. semilanceata,[2] Panaeolus renenosus, Panaeolus subbalteatus, and Copelandia chlorocystis.[3] It was first synthesized by Troxler et al. in 1959.[4]
Little information exists with regard to human pharmacology, but in the book Magic Mushrooms Around the World, author Jochen Gartz reports being aware of a study in which "10 mg of baeocystin were found to be about as psychoactive as a similar amount of psilocybin."[5] Gartz also reported in a research paper that a self-administered assay of 4 mg of baeocystin caused "a gentle hallucinogenic experience".[6]
References[edit]
- ^ Leung AY, Paul AG (1968). "Baeocystin and norbaeocystin: New analogs of psilocybin from Psilocybe baeocystis". Journal of Pharmaceutical Sciences. 57 (10): 1667–71. doi:10.1002/jps.2600571007. PMID 5684732.
- ^ Repke DB, Leslie DT, Guzman G (1977). "Baeocystin in Psilocybe, Conocybe and Panaeolus". Lloydia. 40 (6): 566–78. PMID 600026.
- ^ Brossi A. (1988). The Alkaloids: Chemistry and Pharmacology V32: Chemistry and Pharmacology. Academic Press. p. 46. ISBN 978-0-08-086556-0.
- ^ Troxler, F.; Seeman, F.; Hofmann, A. (1959). "Abwandlungsprodukte von Psilocybin und Psilocin. 2. Mitteilung über synthetische Indolverbindungen". Helvetica Chimica Acta (in German). 42 (6): 2073–2103. doi:10.1002/hlca.19590420638.
- ^ Gartz J. (1997). Magic Mushrooms Around the World. Los Angeles, California: LIS Publications. p. 27. ISBN 978-0-9653399-0-2.
- ^ Gartz J. (1991). "Further Investigations on Psychoactive Mushrooms of the Genera Psylocibe, Gymnopilus and Conocybe" (PDF). Ann. Mus. Civ. Rovereto. 7: 265–74.
