Neuromedin U receptor 1

NMUR1
Identifiers
Aliases	NMUR1, (FM-3), FM-3, FM3, GPC-R, GPR66, NMU1R, Neuromedin U receptor 1
External IDs	MGI: 1341898 HomoloGene: 68501 GeneCards: NMUR1
Gene ontology Molecular function • neuromedin U receptor activity • G-protein coupled receptor activity • signal transducer activity • neuropeptide receptor activity Cellular component • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane • intracellular Biological process • smooth muscle contraction • G-protein coupled receptor signaling pathway • phospholipase C-activating G-protein coupled receptor signaling pathway • chloride transport • neuropeptide signaling pathway • inositol phosphate-mediated signaling • activation of phospholipase C activity • calcium ion transport • calcium-mediated signaling • positive regulation of protein targeting to mitochondrion • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10316	14767
Ensembl	ENSG00000171596	ENSMUSG00000026237
UniProt	Q9HB89	O55040
RefSeq (mRNA)	NM_006056	NM_010341 NM_001319227
RefSeq (protein)	NP_006047	NP_034471.1 NP_001306156.1 NP_001306156 NP_034471
Location (UCSC)	Chr 2: 231.52 – 231.53 Mb	Chr 1: 86.39 – 86.43 Mb
PubMed search
Wikidata
View/Edit Human		View/Edit Mouse

Neuromedin-U receptor 1 is a protein that in humans is encoded by the NMUR1 gene.

See also

• Neuromedin U receptor
• Limostatin

Further reading

• Fujii R, Hosoya M, Fukusumi S, et al. (2000). "Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3.". J. Biol. Chem. 275 (28): 21068–74. doi:10.1074/jbc.M001546200. PMID 10783389. 
• Szekeres PG, Muir AI, Spinage LD, et al. (2000). "Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3.". J. Biol. Chem. 275 (27): 20247–50. doi:10.1074/jbc.C000244200. PMID 10811630. 
• Raddatz R, Wilson AE, Artymyshyn R, et al. (2000). "Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system.". J. Biol. Chem. 275 (42): 32452–9. doi:10.1074/jbc.M004613200. PMID 10899166. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Mori K, Miyazato M, Ida T, et al. (2005). "Identification of neuromedin S and its possible role in the mammalian circadian oscillator system.". EMBO J. 24 (2): 325–35. doi:10.1038/sj.emboj.7600526. PMC 545815. PMID 15635449. 
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621. 

External links

• "Neuromedin U Receptors: NMU1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 
• NMUR1 human gene location in the UCSC Genome Browser.
• NMUR1 human gene details in the UCSC Genome Browser.