Ethacizine

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Ethacizine
Ethacizine.svg
Clinical data
Trade names Ethacizin
AHFS/Drugs.com International Drug Names
ATC code C01BC09 (WHO)
Legal status
Legal status
Pharmacokinetic data
Bioavailability ~40% (oral)[1]
Protein binding 90%
Metabolism Extensive hepatic
Biological half-life 2.5 hours
Identifiers
CAS Number 33414-33-4 YesY
PubChem (CID) 107841
ChemSpider 96982 YesY
UNII FE5SPV1Z6G YesY
ChEMBL CHEMBL1997663 N
Chemical and physical data
Formula C22H27N3O3S
Molar mass 413.54 g/mol
3D model (Jmol) Interactive image

Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent, related to moracizine. It is used in Russia and some other CIS countries for the treatment of severe and/or refractory ventricular and supraventricular arrhythmias, especially those accompanied by organic heart disease. It is also indicated as a treatment of refractory tachycardia associated with Wolff–Parkinson–White syndrome.[1]

It is manufactured under the brand name Ethacizin (Этацизин) by Olainfarm.[2]

References[edit]

  1. ^ a b "Этацизин (Ethacyzin) Prescribing Information. VIDAL Drug Compendium" (in Russian). Retrieved 5 February 2014. 
  2. ^ "Этацизин—4DOKTOR.RU Drug Information Handbook" (in Russian). Retrieved 5 February 2014.